979 resultados para alfredo aquino


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The aim of the study was to compare the efficacy and safety of transvaginal trocar-guided polypropylene mesh insertion with traditional colporrhaphy for treatment of anterior vaginal wall prolapse.This is a randomized controlled trial in which women with advanced anterior vaginal wall prolapse, at least stage II with Ba a parts per thousand yenaEuro parts per thousand+1 cm according to the Pelvic Organ Prolapse Quantification (POP-Q) classification, were randomly assigned to have either anterior colporrhaphy (n = 39) or repair using trocar-guided transvaginal mesh (n = 40). the primary outcome was objective cure rate of the anterior compartment (point Ba) assessed at the 12-month follow-up visit, with stages 0 and I defined as anatomical success. Secondary outcomes included quantification of other vaginal compartments (POP-Q points), comparison of quality of life by the prolapse quality of life (P-QOL) questionnaire, and complication rate between the groups after 1 year. Study power was fixed as 80 % with 5 % cutoff point (p < 0.05) for statistical significance.The groups were similar regarding demographic and clinical preoperative parameters. Anatomical success rates for colporrhaphy and repair with mesh placement groups were 56.4 vs 82.5 % (95 % confidence interval 0.068-0.54), respectively, and the difference between the groups was statistically significant (p = 0.018). Similar total complication rates were observed in both groups, with tape exposure observed in 5 % of the patients. There was a significant improvement in all P-QOL domains as a result of both procedures (p < 0.001), but they were not distinct between groups (p > 0.05).Trocar-guided transvaginal synthetic mesh for advanced anterior POP repair is associated with a higher anatomical success rate for the anterior compartment compared with traditional colporrhaphy. Quality of life equally improved after both techniques. However, the trial failed to detect differences in P-QOL scores and complication rates between the groups.

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RESUMO: Este trabalho teve como objetivo comparar a severidade da mancha de Alternaria de genótipos de girassol em ambientes do Cerrado do Distrito Federal. Três experimentos foram avaliados, dois na Embrapa Cerrados (Planaltina, DF) e um localizado na Embrapa Produtos e Mercado (Recanto das Emas, DF). Foram feitas análises ao longo do ciclo da cultura com um intervalo de 15 dias, sendo a primeira aos 35 dias após emergência. Cada planta foi analisada em três partes: terço inferior, terço médio e terço superior. Ao final de cada experimento, a área abaixo da curva de progresso da doença (AACPD) foi calculada para cada genótipo. De acordo com os resultados observados, o ambiente de sequeiro na Embrapa Cerrados, que deteve a maior média da severidade da doença, entre os ambientes avaliados. Dentre os genótipos avaliados, MG 360 mostrou menor severidade da doença no sequeiro e AGUARA 06 no irrigado da Embrapa Cerrados. O genótipo BSG 42 na Embrapa Produtos e Mercado, se destacou pela menor severidade do fungo. Houve influência significativa do ambiente nos resultados de severidade da doença, que está estreitamente relacionada com os fatores climáticos como temperatura e umidade relativa do ar. A compreensão dessas condições favoráveis ao desenvolvimento do fungo é essencial quando se avalia a resistência em genótipos de girassol. ABSTRACT: This study had the purpose of comparing the severity of Alternaria leaf spot on genotypes of sunflower in the Brazilian Cerrado. Three field trials were established, two at Embrapa Cerrados (Planaltina, DF) and one at Embrapa Produtos e Mercados (Recanto das Emas, DF). Evaluations were made during the crop cycle every 15 days, the first one happening 35 days after crop emergency. Each plant was analyzed in three parts: lower, middle and upper thirds. At the end of each trial the average area under the disease progress curve (AUDPC), for each third, was calculated for all genotypes. According to the observed results, the dryland environment at Embrapa Cerrados had the highest mean disease severity, among the studied environments. Between the evaluated genotypes, MG360 showed less severity in dryland and AGUARA 06 in the irrigated environment at Embrapa Cerrados. At Embrapa Produtos e Mercado the genotype that presented the best performance was BRS G42. Environmental conditions deeply affected the trials, mainly temperature and relative humidity. Their influence on Alternaria leaf spot epidemics in the Cerrado region must be studied in more detail, to avoid misinterpreting data when evaluating sunflower genotypes for resistance to this important fungal disease.

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RESUMO: O presente trabalho tem por objetivo caracterizar o comportamento de 16 genótipos de girassol em ambiente de sequeiro e ambiente irrigado do Cerrado do Distrito Federal visando aumentar disponibilidade de cultivares mais produtivas e adaptadas. Os ensaios foram conduzidos na área experimental da Embrapa Cerrados, Planaltina, DF. Os ensaios foram arranjados experimentalmente em blocos ao acaso, com quatro repetições. Os genótipos avaliados foram: CF 101, ADV 5504, BRS G42, BRS 323, HELIO 250, HELIO 251, SYN 045, SYN 3950HO, MG 305, MG 360, AGUARÁ 04, AGUARÁ 06, PARAÍSO 20, GNZ NEON, HLA 2012 e M734. Os caracteres avaliados foram rendimento estimado de grãos, tamanho do capítulo, peso de mil aquênios, altura de plantas, teor de óleo e dias para floração inicial. Houve diferenças significativas entre os genótipos para todas as características avaliadas. Dos 16 genótipos avaliados, os híbridos SYN 045 (3.786,2 kg ha-1) e MG 305 (4.987,2 kg ha-1) se sobressaíram quanto ao rendimento estimado de grãos. Quanto ao teor de óleo, os híbridos MG 306 (53,95%) e SYN 3950HO (49,49%) se destacaram. Foram identificados os genótipos mais promissores dentre os avaliados, podendo ser explorados em programas de melhoramento que visam o desenvolvimento de cultivares mais adaptadas.

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RESUMO: O objetivo deste trabalho foi estimar caracteres genéticos, fenotípicos e ambientais relacionados aos componentes de produção e caracteres agromorfológicos de girassol em três núcleos rurais do Distrito Federal. Os experimentos foram conduzidos nas áreas experimentais da Embrapa Cerrados, Planaltina, DF, Embrapa Produtos e Mercado, Recanto das Emas, DF e na Fazenda Agua Limpa, da Universidade de Brasília. Através dos resultados obtidos, foram verificadas diferenças significativas entre os genótipos de girassol nos três núcleos rurais do Cerrado para todas as características agronômicas avaliadas. Ainda, baixos coeficientes de variação ambiental para quase todas as características, exceto para o tamanho de capitulo, indicaram boa precisão experimental e altos valores de herdabilidade, coeficientes de variação genéticos e acurácia evidenciaram condições favoráveis à seleção dos materiais para as características agronômicas avaliadas. ABSTRACT: The purpose of this study was to assess genetic, phenotypic and environmental characteristics related to agro-morphological traits of sunflower in three rural centers of Distrito Federal. The experiments were conducted at the experimental areas of Embrapa Cerrados, Planaltina, DF, Embrapa Produtos e Mercado, Recanto das Emas, DF e na Fazenda Agua Limpa, da Universidade de Brasília. Through the obtained results, were verified significate genotypic differences of sunflower at the three rural centers of Brazilian Savannah for all traits evaluated. In addition, low coefficients of environmental variation for almost all trait, except the head size, indicate good experimental precision and high values of heritability, genetic variation and accuracy showed favorable conditions to selecting materials for the agronomic traits evaluated.

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RESUMO:Com o objetivo de avaliar o comportamento agronômico de genótipos de girassol no Cerrado do Distrito Federal, foram conduzidos ensaios na safrinha dos anos de 2014 e 2015, na estação experimental da Embrapa Cerrados, Planaltina, DF. O delineamento experimental foi de blocos ao acaso com quatro repetições, e foram avaliados 12 genótipos de girassol: HLA 2015, NTC 90, SYN 065, M734, BRS G44, HLA 2014, BRS G45, BRS G43, HLA 2013, HLA 2017, BRS G46, HLA 2016. As características avaliadas foram rendimento de grãos, tamanho do capitulo, peso de mil aquênios, altura de plantas e dias de floração inicial. Diferenças significativas foram encontradas para as características avaliadas. Os genótipos que se destacaram em relação ao rendimento de grãos foram HLA 2014 (3.161 kg ha-1) e a testemunha M743 (3.212 kg ha-1). Além disso, o ensaio do ano 2014 apresentou uma média de rendimento maior (2.829 kg ha-1) e mais precoces (63,10 dias) em relação a 2015. O trabalho permitiu a identificação de materiais promissores para exploração em programas de melhoramento genético. ABSTRACT: Aiming the evaluation on agronomic behavior of sunflower genotypes in the Brazilian savannah, experiments were carried on in the second crop of 2014 and 2015 at Centro de Pesquisa Agropecuária dos Cerrados (Embrapa), Planaltina, DF. A complete randomized block design was used with four replications and 12 genotypes of sunflower were analyzed: HLA 2015, NTC 90, SYN 065, M734, BRS G44, HLA 2014, BRS G45, BRS G43, HLA 2013, HLA 2017, BRS G46, HLA 2016.The evaluated characteristics were grain yield, head, weight thousand achenes, plant height, and flowering time. Significant differences were found in all evaluated characteristics. The genotypes that stood out in seed yield were HLA 2014 (3161 kg ha-1) and M743 (3212 kg ha-1). Besides, the 2014 experiment presented a seed yield average higher (2829 kg ha-1), and earlier flowering (63,10 days) when compared to 2015 experiment. This study allowed the identification of promising materials to explore in breeding programs.

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McArdle disease is arguably the paradigm of exercise intolerance in humans. This disorder is caused by inherited deficiency of myophosphorylase, the enzyme isoform that initiates glycogen breakdown in skeletal muscles. Because patients are unable to obtain energy from their muscle glycogen stores, this disease provides an interesting model of study for exercise physiologists, allowing insight to be gained into the understanding of glycogen-dependent muscle functions. Of special interest in the field of muscle physiology and sports medicine are also some specific (if not unique) characteristics of this disorder, such as the so-called 'second wind' phenomenon, the frequent exercise-induced rhabdomyolysis and myoglobinuria episodes suffered by patients (with muscle damage also occurring under basal conditions), or the early appearance of fatigue and contractures, among others. In this article we review the main pathophysiological features of this disorder leading to exercise intolerance as well as the currently available therapeutic possibilities.

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The objective of this study is to compare the incidence and epidemiology of bacteremic community-acquired pneumonia (CAP) in the setting of changes in 13-valent pneumococcal conjugate vaccine (PCV13) coverage. In the region of Madrid, universal immunization with the PCV13 started in May 2010. In July 2012, public funding ceased. Vaccination coverage decreased from >95% to 82% in 2013 and to 67% in 2014. We performed a multicenter surveillance and case-control study from 2009-2014. Cases were hospitalized children with bacteremic CAP. Controls were children selected 1:1 from next-admitted with negative blood cultures and typical, presumed bacterial CAP. Annual incidence of bacteremic CAP declined from 7.9/100 000 children (95% CI 5.1-11.1) in 2009 to 2.1/100 000 children (95% CI 1.1-4.1) in 2012. In 2014, 2 years after PCV13 was withdrawn from the universal vaccination program, the incidence of bacteremic CAP increased to 5.4/100 000 children (95% CI 3.5-8.4). We enrolled 113 cases and 113 controls. Streptococcus pneumoniae caused most of bloodstream infections (78%). Empyema was associated with bacteremia (P = .003, OR 3.6; 95% CI 1.4-8.9). Simple parapneumonic effusion was not associated with bacteremia. Incomplete PCV immunization was not a risk factor for bacteremic pneumonia.

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The intent of this review is to summarize current body of knowledge on the potential implication of the xanthine oxidase pathway (XO) on skeletal muscle damage. The possible involvement of the XO pathway in muscle damage is exemplified by the role of XO inhibitors (e.g., allopurinol) in attenuating muscle damage. Reliance on this pathway (as well as on the purine nucleotide cycle) could be exacerbated in conditions of low muscle glycogen availability. Thus, we also summarize current hypotheses on the etiology of both baseline and exertional muscle damage in McArdle disease, a condition caused by inherited deficiency of myophosphorylase. Because myophosphorylase catalyzes the first step of muscle glycogen breakdown, patients are unable to obtain energy from their muscle glycogen stores. Finally, we provide preliminary data from our laboratory on the potential implication of the XO pathway in the muscle damage that is commonly experienced by these patients.

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The potential of the violoncello as a solo instrument was recognized and supported by cellists such as Luigi Boccherini (1743-1805), Luis Duport (1749-1819), Auguste Franchomme (1808-1884), and Alfredo Piatti (1822-1901). These pioneers composed technically demanding etudes, exercises, and caprices for the cello that were comparable to those already present in the violin literature. Even so, in the late nineteenth century and early twentieth century, considerably fewer substantial works were brought forth for the cello as compared with the violin. Consequently, many cellists such as Luigi Silva (1903-1961), Gregor Piatigorsky (1903-1976), Pierre Fournier (1906-1986), and Janos Starker (b. 1924) selected notable pieces from the violin repertoire and transcribed these for the cello. Some composers themselves actually adapted for the cello their own works originally written for the violin. Johannes Brahms with his Violin Sonata Op. 78, Igor Stravinsky with his Suite Italienne, and Béla Bartók with his First Rhapsody all belong to this category. Adaptations such as these further raised awareness among composers and performers of the possibilities of the cello as an independent and expressive instrument. Thus, many composers from the early 1900s to the present were encouraged to write increasing numbers of more soloistic and demanding works for cello. Herein, I explore the repertoire of cello transcriptions in order to analyze the differences between the original and transcribed versions and the challenges found therein. The performer may attempt to recreate the effect originally intended for the violin or, more daringly, may strive to search for alternate presentations of the music more suitable and expressive of the cello's own character. The project includes two recitals of the following transcribed works presented at the University of Maryland College Park, School of Music: Sonata in A by César Franck, transcribed by Jules Delsart, Variations on a Theme from Rossini by Nicolo Paganini, transcribed by Fournier, Suite Italienne by Igor Stravinsky, transcribed with the help of Piatigorsky, Sonatina Op. 137, No. 1 by Franz Schubert, transcribed by Starker, First Rhapsody by Béla Bartók and Sonata, Op. 108 by Johannes Brahms, transcribed by Hsiao-mei Sun.

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Motivated by the Minimal Dark Matter scenario, we consider the annihilation into gamma rays of candidates in the fermionic 5-plet and scalar 7-plet representations of SU(2)L, taking into account both the Sommerfeld effect and the internal bremsstrahlung. Assuming the Einasto profile, we show that present measurements of the Galactic Center by the H.E.S.S. instrument exclude the 5-plet and 7-plet as the dominant form of dark matter for masses between 1 TeV and 20 TeV, in particular, the 5-plet mass leading to the observed dark matter density via thermal freeze-out. We also discuss prospects for the upcoming Cherenkov Telescope Array, which will be able to probe even heavier dark matter masses, including the scenario where the scalar 7-plet is thermally produced.

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Los contenidos de carbono y nitrógeno orgánicos del suelo están relacionados con su capacidad productiva. Esta relación es esperable que sea más estrecha en suelos de zonas áridas y semiáridas. La cantidad de carbono que puede secuestrar el suelo es, a la vez, de interés por la posibilidad de usar a los suelos como sumideros de carbono y mitigar el efecto invernadero. Esta tesis tiene como objetivo determinar los efectos del sistema de labranza sobre la dinámica del carbono y el nitrógeno en un suelo de una región semiárida. Se realizó un experimento de campo de larga duración en el que se contrastó un manejo tradicional, que empleaba un arado de disco en la labor principal, con un manejo tradicional, que empleaba un arado de disco en la labor principal, con un manejo de siembra directa. Los contenidos de humedad del suelo fueron superiores bajo siembra directa y mayores también los rendimientos de los cultivos que integraban la rotación siendo, consecuentemente, los aportes de carbono en forma de residuos al suelo también mayores. El flujo anual de carbono emitido a la atmósfera como C - CO2 fue similar entre sistemas de labranza, de lo que resultó un balance de carbono neutro bajo siembra directa y negativo bajo labranza con arado. La producción de C - CO2 aumentó con la cantidad de residuos presentes en el suelo y la temperatura y decrecía al incrementarse la cantidad de nitratos. La descomposición de los residuos vegetales y la liberación al suelo de su nitrógeno fue más rápida en el suelo labrado, lo que llevó a mayores niveles de nitratos a la siembra de algunos cultivos en el tratamiento con labranza en casi todos los cultivos integrantes de la rotación. Bajo siembra directa el suelo no perdió carbono durante el experimento mientras que bajo arado de disco el stock de carbono orgánico del suelo decreció. En regiones semiáridas la adopción de siembra directa determina balances de carbono menos negativos que bajo manejos con labranza, por incrementar las entradas de carbono al suelo y no afectar las salidas por respiración heterótrofa.

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El objetivo de este trabajo fue evaluar la eficiencia del modelo de Green-Ampt en la predicción de la infiltración del agua en el suelo haciendo uso de funciones de pedotransferencia (FPT) de Saxton y Rawls (SR), Wösten y Nemes (WN) y las del programa Rosetta (ROS) y analizar el efecto de la carga animal sobre este proceso, por medio de los modelos empíricos de Mezencev (Mez) y el de Swarzendruber (SW), en un establecimiento de producción animal. El estudio se llevó a cabo en un establecimiento sito en la localidad de Marcos Paz, Pcia. de Bs.As. Se eligieron dentro del predio, cuatro grupos de sectores de acuerdo a la intensidad de carga (Ic) : nula (testigo), media, alta y muy alta. El proceso de infiltración se relevó por medio de anillos de Muntz hasta alcanzar la tasa de infiltración básica (TIB). Se tomaron muestras para determinar la densidad aparente (DA), carbono total (CT), humedad gravimétrica (H), conductividad hidráulica saturada (Ks) y se midió la resistencia a la penetración (Rp). Se llevaron a cabo en total 70 ensayos de infiltración y los resultados permitieron concluir que: 1) La carga animal produjo solamente efectos notorios de disminución de la TIB para muy alta Ic. 2) El modelo de SW resultó describir el fenómeno desde el punto de vista físico mejor que el de Mez. 3) La predicción del modelo de GA resultó satisfactoria utilizando las FPT de WN, pero no con las de SR o ROS. 4) Los valores de Ks medidos resultaron entre 5 y 10 veces mayores que los correspondientes de TIB. 5) La TIB dependió sólo de las variables Ic, DA y CT en un modelo de regresión lineal

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El cultivo de maíz pisingallo (Zea mays L. var. everta) es una alternativa conveniente en la diversificación de la producción de granos en Argentina, sin embargo las bases ecofisiológicas de la determinación del rendimiento y la calidad han sido fundamentadas sobre maíces de tipo dentado, mientras que en maíces pisingallo se desconocen. El objetivo de esta tesis es entender cómo los maíces pisingallos determinan sus componentes del rendimiento, el nivel de proteína en grano y su volumen de expansión (principal criterio de calidad comercial) por medio de un marco conceptual basado en el crecimiento y partición de biomasa del cultivo en torno a floración y durante el llenado efectivo de los granos. Durante 2007 y 2008 se llevaron a cabo tres experimentos a campo en donde la tasa de crecimiento por planta fue alterada por medio de tratamientos de densidad de siembra y de raleo de plantas y defoliaciones (en torno a floración y durante el llenado efectivo) en 4 genotipos dentados y 8 pisingallos. Ambos tipos de maíz tuvieron en común una fuerte asociación de su rendimiento con la capacidad potencial de rendimiento establecida en torno a floración (R2 igual a 0,93, p menor a 0,001), pero difirieron en la determinación del peso de grano. El peso de grano potencial en maíces pisingallos siempre fue menor ante una misma disponibilidad de asimilados por grano en torno a floración (p menor a 0,05), mientras que el peso final de grano se redujo menos que el de los dentados ante una misma disminución en la disponibilidad de asimilados durante el llenado (p menor a 0,05). La concentración y contenido de proteínas del grano, y su volumen de expansión, estuvieron asociados principalmente a la tasa de crecimiento por planta por grano durante el llenado efectivo, y en menor medida con dicha tasa en torno a floración. Los resultados de esta tesis resaltan la importancia de las condiciones de crecimiento en torno a floración para la determinación del rendimiento dentro de un conjunto diverso de germoplasma de maíz (dentado y pisingallo) y demuestran, por primera vez, que el volumen de expansión de grano de maíz pisingallo puede ser predicho a partir del crecimiento del cultivo.