700 resultados para Stoltze, FriedrichStoltze, FriedrichFriedrichStoltze


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Stoltze in Königstein, Warnung vor der Rückkehr

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Bitte um Unterstützung einer armen Familie

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Bittbrief, Persönliche Nachrichten, Johann Albrecht Vogtherr, Seydewitz, Prüning, Leopold Sonnemann, Carl Holthof, Oppel, Miquel

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Persönliche Nachrichten

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Glückwünsche zum 80. Geburtstag

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Stoltze: Totenmaske, Friedrich Schierholz

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"Schalck-Stoltzesche Angelegenheit", Auseinandersetzung um Eigentumsrechte an der Frankfurter Latern

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Eigentumsrechte an der Frankfurter Latern

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Bitte um Nachdruck-Erlaubnis für eine Hampelmann-Kolumne im "Stuttgarter Beobachter", Bitte um Auskunft zu einer historischen Anekdote

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Im Gefängnis Heilbronn, "Alte Neuigkeiten", Persönliche Nachrichten

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FOXP3-expressing naturally occurring CD4(+)CD25(high) T regulatory cells (Treg) are relevant in the control of autoimmunity, and a defect in this cell population has been observed in several human autoimmune diseases. We hypothesized that altered functions of peripheral Treg cells might play a role in the immunopathogenesis of myasthenia gravis, a T cell-dependent autoimmune disease characterized by the presence of pathogenic autoantibodies specific for the nicotinic acetylcholine receptor. We report in this study a significant decrease in the in vitro suppressive function of peripheral Treg cells isolated from myasthenia patients in comparison to those from healthy donors. Interestingly, Treg cells from prednisolone-treated myasthenia gravis patients showed an improved suppressive function compared with untreated patients, suggesting that prednisolone may play a role in the control of the peripheral regulatory network. Indeed, prednisolone treatment prevents LPS-induced maturation of monocyte-derived dendritic cells by hampering the up-regulation of costimulatory molecules and by limiting secretion of IL-12 and IL-23, and enhancing IL-10. In addition, CD4(+) T cells cultured in the presence of such tolerogenic dendritic cells are hyporesponsive and can suppress autologous CD4(+) T cell proliferation. The results shown in this study indicate that prednisolone treatment promotes an environment that favors immune regulation rather than inflammation.

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in altfrankfurter Tagen begründet von Friedrich Stoltze

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Friedrich Stoltze

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von Brunnenhilde Sündflutia Wolkenbruch, Wasserdichterin