spotlight europe #2012/07 — Dezember 2012: Die Union gegen die Banken = The Union against the banks

No abstract.

Russian sanctions against Moldova. Minor effects, major potential. OSW COMMENTARY No. 152, 2014-11-06

Russia has been Moldova’s main trade partner and Russian capital has accounted for a large part of its foreign investments, dominating in the energy and the banking sectors. Moreover, Russia has been a key job market for Moldovan expatriate workers. In the economic sphere, this is making Moldova unilaterally dependent on Russia. Moscow has been attempting to exploit this situation to put pressure on the authorities in Chișinău for quite some time. In recent months Russia has increasingly used instruments for exerting economic pressure on Moldova, as a means of responding to the current authorities’ pro-Western policy. A key element of this policy was Moldova’s signing on 27 June 2014 of the Association Agreement with the EU (which came into force on 1 September 2014). Over the last year, Russia has implemented a number of import restrictions on Moldovan goods. The aim of the Russian actions is to fuel social disappointment, and ultimately – to prevent the pro-European coalition currently in power from winning the parliamentary elections scheduled for 30 November 2014. Another aim might be to convince the Moldovan authorities to suspend the implementation of the Association Agreement – a plan openly put forward by Vladimir Putin during the CIS summit in Minsk on 10 October 2014. So far, however, the Russian economic sanctions have failed to produce the expected results. Support for the pro-European parties has been high, and there is little chance that the pro-Russian groups might achieve a parliamentary majority. It is not inconceivable, then, that in the upcoming months Moscow might decide to resort to other, more potent instruments of economic pressure such as speculation on the financial market, carried out as part of its de facto control over the banking sector. Another possibility is further tightening of trade restrictions, issuing expatriate workers from Russia or using Moldova’s dependence on Russian energy.

Immunization with a circumsporozoite epitope fused to Bordetella pertussis adenylate cyclase in conjunction with cytotoxic T-lymphocyte-associated antigen 4 blockade confers protection against Plasmodium berghei liver-stage malaria

The adenylate cyclase toxoid (ACT) of Bordetella pertussis is capable of delivering its N-terminal catalytic domain into the cytosol of CD11b-expressing professional antigen-presenting cells such as myeloid dendritic cells. This allows delivery of CD8+ T-cell epitopes to the major histocompatibility complex (MHC) class I presentation pathway. Recombinant detoxified ACT containing an epitope of the Plasmodium berghei circumsporozoite protein (CSP), indeed, induced a specific CD8+ T-cell response in immunized mice after a single application, as detected by MHC multimer staining and gamma interferon (IFN-gamma) ELISPOT assay. This CSP-specific response could be significantly enhanced by prime-boost immunization with recombinant ACT in combination with anti-CTLA-4 during the boost immunization. This increased response was accompanied by complete protection in a number of mice after a challenge with P. berghei sporozoites. Transient blockade of CTLA-4 may overcome negative regulation and hence provide a strategy to enhance the efficacy of a vaccine by amplifying the number of responding T cells.

Complete protection against P. berghei malaria upon heterologous prime/boost immunization against circumsporozoite protein employing Salmonella type III secretion system and Bordetella adenylate cyclase toxoid

Sterile immunity against malaria can be achieved by the induction of IFNgamma-producing CD8(+) T cells that target infected hepatocytes presenting epitopes of the circumsporozoite protein (CSP). In the present study we evaluate the protective efficacy of a heterologous prime/boost immunization protocol based on the delivery of the CD8(+) epitope of Plasmodium berghei CSP into the MHC class I presentation pathway, by either a type III secretion system of live recombinant Salmonella and/or by direct translocation of a recombinant Bordetella adenylate cyclase toxoid fusion (ACT-CSP) into the cytosol of professional antigen-presenting cells (APCs). A single intraperitoneal application of the recombinant ACT-CSP toxoid, as well as a single oral immunization with the Salmonella vaccine, induced a specific CD8(+) T cell response, which however conferred only a partial protection on mice against a subsequent sporozoite challenge. In contrast, a heterologous prime/boost vaccination with the live Salmonella followed by ACT-CSP led to a significant enhancement of the CSP-specific T cell response and induced complete protection in all vaccinated mice.

Every woman's right : the right to quality education and economic independence /

"National Chicana Foundation, Inc., Montebello, California."

Data pertinent to the establishment of minimum wage rates under the Fair labor standards act for employment newly covered by the amendments of 1966 in the construction industry in Puerto Rico /

"WH67-641."

Data pertinent to the establishment of minimum wage rates under the Fair labor standards act for newly covered employment in the laundry and cleaning industry in Puerto Rico /

"WH67-301"

Data pertinent to the establishment of minimum wage rates under the Fair labor standards act for newly covered employment in the local transit industry in Puerto Rico /

"WH67-378."

Report of the United States Commission on Civil Rights on the Civil Rights Act of 1990.

Item 288-A

Data pertinent to the review of minimum wage rates under the Fair Labor Standards Act in the construction industry in Puerto Rico : Part 1, General information /

"September 1968."

The Virginia workmen's compensation act. With annotations, court decisions construing the act and formal rules of the Industrial commission. Industrial Commission of Virginia.

Amendments ... enacted ... 1952, bound with.

Long-Term Care Assistance Act of 1988 [microform] : hearings before the Subcommittee on Health of the Committee on Finance, United States Senate, One Hundredth Congress, second session, on S. 2305, May 27, and June 17, 1988.

CIS Microfiche Accession Numbers: CIS 89 S361-23

Report, proceedings and evidence of the Select Standing Committee on Industrial and International relations upon the question of insurance against unemployment, sickness and invalidity as ordered by the House on the 14th of February, 1929 : Third session of the sixteenth Parliament of Canada.

Includes index.

Canadian workmen's compensation acts and cases : containing comparative tables and references to the acts of British Columbia, Alberta, Manitoba and Saskatchewan, together with a digest of cases decided thereunder and comparative references to the English act of 1906 /

Mode of access: Internet.

Women's educational equity act; annual report.

Includes index.