EPI Update, March 14, 2008

Weekly newsletter for Center For Acute Disease Epidemiology of Iowa Department of Public Health.

Kansanedustaja Erkki Huurtamo 14/12 1973

Kirje 14.12.1973

Helsinki 14.7.1924

Kirje

Effects of a treatment gap during adjuvant chemotherapy in node-positive breast cancer: results of International Breast Cancer Study Group (IBCSG) Trials 13-93 and 14-93.

BACKGROUND: The International Breast Cancer Study Group (IBCSG) conducted two complementary randomized trials to assess whether a treatment-free gap during adjuvant chemotherapy influenced outcome. PATIENTS AND METHODS: From 1993 to 1999, IBCSG Trials 13-93 and 14-93 enrolled 2215 premenopausal and postmenopausal women with axillary node-positive, operable breast cancer. All patients received cyclophosphamide (Cytoxan, C) plus either doxorubicin (Adriamycin, A) or epirubicin (E) for four courses followed immediately (No Gap) or after a 16-week delay (Gap) by classical cyclophosphamide, methotrexate, and fluorouracil (CMF) for three courses. The median follow-up was 7.7 years. RESULTS: The Gap and No-Gap groups had similar disease-free survival (DFS) and overall survival (OS). No identified subgroup showed a statistically significant difference, but exploratory subgroup analysis noted a trend towards decreased DFS for Gap compared with No Gap for women with estrogen receptor (ER)-negative tumors not receiving tamoxifen, especially evident during the first 2 years. CONCLUSIONS: A 16-week gap between adjuvant AC/EC and CMF provided no benefit and may have increased early recurrence rates in patients with ER-negative tumors.

Lottery Action, Vol. 15, no. 14 July 12-August 3, 2008

Iowa Lottery Authority Newsletter For Lottery Retailers

Kansanedustaja Pertti Salolainen 14/4 1971

Kirje 14.4.1971

Imparidade de Activos e o Impacto da sua Aplicação

O presente trabalho tem como objectivo, por um lado, debruçar sobre a Norma de Relato Financeiro que trata de imparidade de activos (NRF 17), e, por outro lado, identificar os possíveis impactos decorrentes da sua aplicação. Assim, depois de todo o desenvolvimento teórico da Norma, foi então realizado um estudo de caso, a fim de analisar e identificar os possíveis impactos. Os principais resultados indicam que a aplicação da NRF 17 tem tido um impacto significativo, visto que, essa norma ainda não é aplicada pela maioria das empresas, os contabilistas, assim como as empresas necessitam de maior qualificação no que diz respeito a essa matéria, e também, constata-se que a sua aplicação tem muito impacto nos activos como nas fases do processo contabilístico. Conclui-se também que, das que aplicam a norma, a sua maioria tem identificado activos com imparidade e que essa aplicação tem dado contributo positivo na qualidade das demonstrações financeiras (DF).

EPI Update, November 14, 2008

Weekly newsletter for Center For Acute Disease Epidemiology of Iowa Department of Public Health.

Fil. dr Johannes Salminen 14.2.1967 Härstädes

Kirje

Evaluación de la contaminación marina en la Bahía Ferrol, Chimbote. 14 - 18 Julio 1994

Evalúa la calidad del medio marino en la Bahía de Ferrol, Chimbote; donde se realizó un muestreo simultáneo por mar y playa, durantre una época de intensa actividad industrial pesquera. Los resultados del análisis concluyen en que la bahía presenta signos serios de deterioro ambiental, con el desarrollo de procesos eutróficos que conllevan a una pérdida de condiciones ambientales apropiadas, en perjuicio de los recursos hidrobiológicos costeros.

IFRS introduction and its effect on listed companies in Spain

From the beginning of January 2005 publicly traded companies in the European Union have to comply with the International Financial Reporting Standards (IFRS) for their consolidated accounts, as required by 1606/2002 European Commission Regulation. It had been suggested that the new accounting rules will facilitate not only the process of international harmonization of financial statements, but also efficient performance of financial markets and capital flows worldwide. This study analyzes the first results of IFRS implementation by Spanish non-financial listed companies.