918 resultados para Globe céleste


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O presente ensaio aborda a literatura de viagem sobre o Brasil, escrita ao longo dos séculos XVI, XVII e XVIII, com o intuito de extrair, daí, uma pequena amostra da imagem que os europeus construíram de um dos traços que, aos seus olhos, mais se destacavam na população local: a religiosidade desmedida e festiva. Trata-se, pois, de uma tentativa muito limitada de mapear uma pequena parte das “verdades” sobre o Brasil e suas gentes que o habitante do Velho Mundo construiu e partilhou ao longo dos séculos, verdades que, em larga medida, guiaram as suas ações nesta parte do globo.

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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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Obesity is increasing throughout the globe and characterized by excess adipose tissue, which represents a complex endocrine organ. Adipose tissue secrets bioactivemolecules called adipokines, which act at endocrine, paracrine, and autocrine levels. Obesity has recently been shown to be associated with periodontitis, a disease characterized by the irreversible destruction of the tooth-supporting tissues, that is, periodontium, and also with compromised periodontal healing. Although the underlying mechanisms for these associations are not clear yet, increased levels of proinflammatory adipokines, such as leptin, as found in obese individuals, might be a critical pathomechanistic link. The objective of this study was to examine the impact of leptin on the regenerative capacity of human periodontal ligament (PDL) cells and also to study the local leptin production by these cells. Leptin caused a significant downregulation of growth (TGF beta 1, and VEGFA) and transcription (RUNX2) factors as well as matrix molecules (collagen, and periostin) and inhibited SMAD signaling under regenerative conditions. Moreover, the local expression of leptin and its full-length receptor was significantly downregulated by inflammatory, microbial, and biomechanical signals. This study demonstrates that the hormone leptin negatively interferes with the regenerative capacity of PDL cells, suggesting leptin as a pathomechanistic link between obesity and compromised periodontal healing.

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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The globalization is each day more aggressive and demanding even more that new products be manufactured and therefore be delivered to many places in the globe. Thus, an efficient and vigorous transport system is demanded. There are many ways to transport a product, but one of the most used in the world is shipping. A marine vessel presents diversified structures of size and functions. In order to this system has more efficiency, alternatives should be used to obtain important energy savings. Usually, a vessel present a propulsion system purely mechanical, therefore the use of alternatives propulsions, like diesel-electric, is increasing. This graduation work has as main focus demonstrate the functioning of a diesel-electric propulsion system, since the main characteristics of each component of the system, likewise the analysis and electrical calculation, showing the advantages in relation to the conventional diesel propulsion system

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Along the Earth globe we can find many types of psychoactive plants. Among them is the Ipomoea violacea, popularly known as Morning Glory. There are ergotalkaloids producer associated-fungus in its leaves and seeds. One of these alkaloids that can be found is the ergine (or LSA), a homologous substance of the lysergic acid diethylamide (LSD). There are many discussions around the world about the inclusion of LSA in the list of controlled substances. In Brazil, this was recently prohibited. One of the most important point of view in the study of isotopic composition of 13C and 15N of this plant is the fact that there is a total alkaloid variation in function of its geographic origin like was verified in 1960’s, besides to aggregate knowledge about it. This work was made to verify if the isotopic ratio can be used as a tool in tracing this illegal Brazilian plant. We could conclude that this plant presents a C3 photosynthetic pathway, its parts has different isotopic carbon and nitrogen composition and that stable isotope analysis can be successfully used as a tool to detect its geographic origin

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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

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Pós-graduação em Economia - FCLAR

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Pós-graduação em Comunicação - FAAC

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Pós-graduação em Agronomia (Horticultura) - FCA

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Pós-graduação em Ciência e Tecnologia Animal - FEIS

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Pós-graduação em Televisão Digital: Informação e Conhecimento - FAAC