Mitochondrial polymorphisms are associated both with increased and decreased longevity

artículo (arbitrado) -- Universidad de Costa Rica, Centro de investigaciones en Biología Celular y Molecular, 2008. Este documento es privado debido a limitaciones de derechos de autor.

The Demobilized Body: Transgressions of Personal Space and Political Participation

Grounded in the intersection between gender politics and electoral studies, this dissertation examines the demobilizing effects of violations of personal space (in the form of domestic violence, control over mobility, emotional abuse, and sexual harassment) on the propensity to vote. Using quantitative methods across four survey datasets concerning Lebanon, the United States, Morocco, and Yemen, this research concludes that cross-regionally, familial control over mobility reduces the propensity to vote among women. Conversely, mechanisms of empowerment such as education and employment increase the propensity to vote.

Os forrós da Serra da Gameleira (São Tomé/RN) : etnicidade, festa e sociabilidade

This work intends to describe and analyze the parties of forró that happen in Serra da Gameleira, in São Tomé/RN. Serra is a divided social space: groups of different ethnic origins live together in Gameleira de Baixo, Salgadinho (or Gameleira de Cima) and Chaves Belas. They are approximately two hundred families that live exclusively from agriculture. We try to understand how the parties inform about the social organization, the ethnic composition of the families that live there and the past of Serra, through the genealogy offorró players. In the discussion, we identify the festive places: in the total, we have Five houses of forró that function regularly one of them has been described. The private and public spaces inside them are intimate related, with no clear limits between the house of forró and the residence. Each house of forró has an owner, that regularly makes the parties, mobilizing a big part of the inhabitants, and provoking the straitening of the social relations. Observing the festive sociability between different social segments, the forró appears like na element that minimizes social conflicts, providing news ways of association and cooperation in the space of Serra da Gameleira. For the collection of facts, we used the ethnographic method, through the direct observation, interviewing and documentary research. The local history is recounted following the routes of oral memory and historical documents analysis. In the end of the analysis, we concluded that music and party are elements that aggregate the different groups that live in the location and determine forms of expression of what is seen as a traditional culture

Diccionario biográfico de la Catedral de Córdoba (I): Los miembros del cabildo en época moderna

Esta publicación recoge la primera parte del estudio biográfico de un conjunto representativo de los miembros del cabildo de una catedral española, la de Córdoba, entre finales del siglo XV y los primeros años del XIX. Para ello, he optado por el formato de entradas simplificadas con los datos básicos sobre el origen, la filiación, los estudios y la carrera de varios cientos de eclesiásticos.

Práctica genealógica y legitimación social en la España moderna. Los Macanaz (siglos XVII-XVIII)

En este texto analizamos el uso del discurso genealógico como medio de legitimación social en la España Moderna. Estudiamos el caso de la familia castellana de los Macanaz y las imágenes genealógicas construidas ad hoc por don Melchor Macanaz. Finalmente nos interesamos por las implicaciones del relato genealógico tradicional en las primeras aproximaciones historiográficas sobre la familia.

The dynamics of Brazilian protozoology over the past century

Brazilian scientists have been contributing to the protozoology field for more than 100 years with important discoveries of new species such as Trypanosoma cruzi and Leishmania spp. In this work, we used a Brazilian thesis database (Coordination for the Improvement of Higher Education Personnel) covering the period from 1987-2011 to identify researchers who contributed substantially to protozoology. We selected 248 advisors by filtering to obtain researchers who supervised at least 10 theses. Based on a computational analysis of the thesis databases, we found students who were supervised by these scientists. A computational procedure was developed to determine the advisors’ scientific ancestors using the Lattes Platform. These analyses provided a list of 1,997 researchers who were inspected through Lattes CV examination and allowed the identification of the pioneers of Brazilian protozoology. Moreover, we investigated the areas in which researchers who earned PhDs in protozoology are now working. We found that 68.4% of them are still in protozoology, while 16.7% have migrated to other fields. We observed that support for protozoology by national or international agencies is clearly correlated with the increase of scientists in the field. Finally, we described the academic genealogy of Brazilian protozoology by formalising the “forest” of Brazilian scientists involved in the study of protozoa and their vectors over the past century.

Figure(s) de sang : amours secrètes, troubles fratries et « miscégénation » dans The Searchers, The Unforgiven et The Missing

International audience

Dialética, linguagem e genealogia : sobre o programa da dialética negativa de Adorno

Gostaria aqui de formular o programa mais geral, contido na Dialética Negativa de Adorno, a partir de algumas perspectivas histórico-filosóficas. Na primeira parte, procuro desenvolver a ideia de que a crítica de Adorno a Hegel, compreendida como um novo enlace entre dialética e ontologia, beneficia-se da interpretação proposta por Adorno de temas da filosofia kantiana (1). Em seguida, procuro mostrar como Adorno conecta sua reformulação da dialética a uma compreensão de linguagem fortemente devedora de estratégias genealógicas de argumentação (2). ______________________________________________________________________________ ABSTRACT

Charcot Marie Tooth disease (CMT4A) due to GDAP1 mutation: report of a colombian family

Background: Mutations of GDAP1 gene cause autosomal dominant and autosomal recessive Charcot-Marie-Tooth disease and more than 40 different mutations have been reported. The recessive Q163X mutation has been described in patients of Spanish ancestry, and a founder mutation in South American patients, originating in Spain has been demonstrated. Objective: We describe physical and histological features, and the molecular impact of mutation Q163X in a Colombian family. Methods: We report two female patients, daughters of consanguineous parents, with onset of symptoms within the first two years of life, developing severe functional impairment, without evidence of dysmorphic features, hoarseness or diaphragmatic paralysis. Electrophysiology tests showed a sensory and motor neuropathy with axonal pattern. Sequencing of GDAP1 gene was requested and the study identified a homozygous point mutation (c.487 C>T) in exon 4, resulting in a premature stop codon (p.Q163X). This result confirms the diagnosis of Charcot-Marie-Tooth disease, type 4A. Results: The patients were referred to Physical Medicine and Rehabilitation service, in order to be evaluated for ambulation assistance. They have been followed by Pulmonology service, for pulmonary function assessment and diaphragmatic paralysis evaluation. Genetic counseling was offered. The study of the genealogy of the patient, phenotypic features, and electrophysiological findings must be included as valuable tools in the clinical approach of the patient with Charcot-Marie-Tooth disease, in order to define a causative mutation. In patients of South American origin, the presence of GDAP1 gene mutations should be considered, especially the Q163X mutation, as the cause of CMT4A disease.

Charcot Marie Tooth disease (CMT4A) due to GDAP1 mutation: report of a colombian family

Background: Mutations of GDAP1 gene cause autosomal dominant and autosomal recessive Charcot-Marie-Tooth disease and more than 40 different mutations have been reported. The recessive Q163X mutation has been described in patients of Spanish ancestry, and a founder mutation in South American patients, originating in Spain has been demonstrated. Objective: we describe physical and histological features, and the molecular impact of mutation Q163X in a Colombian family. Methods: We report two female patients, daughters of consanguineous parents, with onset of symptoms within the first two years of life, developing severe functional impairment, without evidence of dysmorphic features, hoarseness or diaphragmatic paralysis. Electrophysiology tests showed a sensory and motor neuropathy with axonal pattern. Sequencing of GDAP1 gene was requested and the study identified a homozygous point mutation (c.487 C>T) in exon 4, resulting in a premature stop codon (p.Q163X). This result confirms the diagnosis of Charcot-Marie-Tooth disease, type 4A. Results: The patients were referred to Physical Medicine and Rehabilitation service, in order to be evaluated for ambulation assistance. They have been followed by Pulmonology service, for pulmonary function assessment and diaphragmatic paralysis evaluation. Genetic counseling was offered. The study of the genealogy of the patient, phenotypic features, and electrophysiological findings must be included as valuable tools in the clinical approach of the patient with Charcot-Marie-Tooth disease, in order to define a causative mutation. In patients of South American origin, the presence of GDAP1 gene mutations should be considered, especially the Q163X mutation, as the cause of CMT4A disease.

"10 años y divorciada", un film de Khadija Al-Salami

En Yemen no hay que ser mayor de edad para contraer matrimonio, ni tan siquiera se exige una edad mínima. Nojoom es obligada a casarse a los 10 años de edad con un hombre que solo busca una mujer joven para complacerse sexualmente y una sierva para sustituir a su madre en las labores domésticas. Un arreglo legítimo según las leyes locales, aceptado por todos, excepto para la pequeña Nojoom. La cineasta Khadija Al-Salami denuncia la situación que viven miles de niñas en su país, sometidas a leyes atávicas que hoy siguen constituyendo una grave violación de los derechos humanos que afecta a los seres más indefensos, los niños.

The official roster of South Carolina soldiers, sailors and marines in the World War, 1917-18, volume 1, part 1

This is the Official Roster of the South Carolina soldiers, sailors and marines who served in the World War and contains the names and records, briefly compiled, of the men and women from this state who responded to the call of the President when the United States entered the great conflict. This record gives in as compact form as practicable the following : name; serial number; residence; branch of service; date and place of entry into service; place of birth and age; organizations served in, with dates of assignments and transfers; grades with dates of appointment; engagements, if any; wound received in action, with degree and date; if killed in action or died while in service; person notified, relationship and address; oversea service; date of discharge; citations.

The official roster of South Carolina soldiers, sailors and marines in the World War, 1917-18, volume 1, part 2

This is the Official Roster of the South Carolina soldiers, sailors and marines who served in the World War and contains the names and records, briefly compiled, of the men and women from this state who responded to the call of the President when the United States entered the great conflict. This record gives in as compact form as practicable the following : name; serial number; residence; branch of service; date and place of entry into service; place of birth and age; organizations served in, with dates of assignments and transfers; grades with dates of appointment; engagements, if any; wound received in action, with degree and date; if killed in action or died while in service; person notified, relationship and address; oversea service; date of discharge; citations.

The official roster of South Carolina soldiers, sailors and marines in the World War, 1917-18, volume 1, part 3

This is the Official Roster of the South Carolina soldiers, sailors and marines who served in the World War and contains the names and records, briefly compiled, of the men and women from this state who responded to the call of the President when the United States entered the great conflict. This record gives in as compact form as practicable the following : name; serial number; residence; branch of service; date and place of entry into service; place of birth and age; organizations served in, with dates of assignments and transfers; grades with dates of appointment; engagements, if any; wound received in action, with degree and date; if killed in action or died while in service; person notified, relationship and address; oversea service; date of discharge; citations.