Of missing fathers and Big Fish: reconstructive tendencies after postmodernism

Many things have been said about literature after postmodernism, but one point there seems to be some agreement on is that it does not turn its back radically on its postmodernist forerunner, but rather generally continues to heed and value their insights. There seems to be something strikingly non-oedipal about the recent aesthetic shift. It is a project of reconstruction that remains deeply rooted in postmodernist tenets. Such an essentially non-oedipal attitude, I would argue, is central to the nature of the reconstructive shift. This, however, also raises questions about the wider cultural context from which such an aesthetic stance arises. If postmodernism was nurtured by the revolutionary spirits of the late 1960s, reconstruction faces a different world with different strategies. Instead of the postmodernist urge to subvert, expose and undermine, reconstruction yearns towards tentative and fragile intersubjective understanding, towards responsibility and community. Instead of revolt and rebellion it explores reconciliation and compromise. One instance in which this becomes visible in reconstructive narratives is the recurring figure of the lost father. Missing father figures abound in recent novels by authors like Mark Z. Danielewski, Dave Eggers, Yann Mantel, David Mitchell etc. It almost seems like a younger generation is yearning for the fathers which postmodernism has struggled hard to do away with. My paper will focus on one particularly striking example to explore the implications of this development: Daniel Wallace’s novel Big Fish and Tim Burton’s well-known film adaptation of the same. In their negotiation of fact and fiction, of doubt and belief, of freedom and responsibility, all of which converge in a father-son relationship, they serve well to illustrate central characteristics and concerns of recent attempts to leave postmodernism behind.

Chemical studies of elements with Z ⩾ 104 in gas phase

Chemical investigations of superheavy elements in the gas-phase, i.e. elements with Z≥104Z≥104, allow assessing the influence of relativistic effects on their chemical properties. Furthermore, for some superheavy elements and their compounds quite unique gas-phase chemical properties were predicted. The experimental verification of these properties yields supporting evidence for a firm assignment of the atomic number. Prominent examples are the high volatility observed for HsO4 or the very weak interaction of Cn with gold surfaces. The unique properties of HsO4 were exploited to discover the doubly-magic even–even nucleus 270Hs and the new isotope 271Hs. The combination of kinematic pre-separation and gas-phase chemistry allowed gaining access to a new class of relatively fragile compounds, the carbonyl complexes of elements Sg through Mt. A not yet resolved issue concerns the interaction of Fl with gold surfaces. While competing experiments agree on the fact that Fl is a volatile element, there are discrepancies concerning its adsorption on gold surfaces with respect to its daughter Cn. The elucidation of these and other questions amounts to the fascination that gas-phase chemical investigations exert on current research at the extreme limits of chemistry today.

A full pedigree based method for the statistical assessment of genetic anticipation

Genetic anticipation is defined as a decrease in age of onset or increase in severity as the disorder is transmitted through subsequent generations. Anticipation has been noted in the literature for over a century. Recently, anticipation in several diseases including Huntington's Disease, Myotonic Dystrophy and Fragile X Syndrome were shown to be caused by expansion of triplet repeats. Anticipation effects have also been observed in numerous mental disorders (e.g. Schizophrenia, Bipolar Disorder), cancers (Li-Fraumeni Syndrome, Leukemia) and other complex diseases. ^ Several statistical methods have been applied to determine whether anticipation is a true phenomenon in a particular disorder, including standard statistical tests and newly developed affected parent/affected child pair methods. These methods have been shown to be inappropriate for assessing anticipation for a variety of reasons, including familial correlation and low power. Therefore, we have developed family-based likelihood modeling approaches to model the underlying transmission of the disease gene and penetrance function and hence detect anticipation. These methods can be applied in extended families, thus improving the power to detect anticipation compared with existing methods based only upon parents and children. The first method we have proposed is based on the regressive logistic hazard model. This approach models anticipation by a generational covariate. The second method allows alleles to mutate as they are transmitted from parents to offspring and is appropriate for modeling the known triplet repeat diseases in which the disease alleles can become more deleterious as they are transmitted across generations. ^ To evaluate the new methods, we performed extensive simulation studies for data simulated under different conditions to evaluate the effectiveness of the algorithms to detect genetic anticipation. Results from analysis by the first method yielded empirical power greater than 87% based on the 5% type I error critical value identified in each simulation depending on the method of data generation and current age criteria. Analysis by the second method was not possible due to the current formulation of the software. The application of this method to Huntington's Disease and Li-Fraumeni Syndrome data sets revealed evidence for a generation effect in both cases. ^

Volume 11, Number 2: April/May 2005

Page 2 – The Vice Provost cites 2004/2005 as a year of significant accomplishments for the Libraries. • The Dodd Research Center and the Human Rights Institute plan a conference on economic human rights for October. Page 3 - Researcher Bill V. Mullen talks about the work of avant garde musician, composer, and author Fred Ho, whose archive is in Archives & Special Collections. Page 4 - Students tell us why they come to the library. • The Dodd Research Center commissions two students to create a logo for its 10th anniversary celebration. • Fragile pamphlets are given new life in the Conservation Lab. Page 5 - The library sponsors a national symposium to explore new technology. • Our newest digital project can lead you to everything you ever wanted to know about Connecticut. • A new Pharmacy Library will open its doors in June. Page 6 - Staff News: service anniversaries and new faces. Page 7 - The Class of 1955 is raising $50,000 for an undergraduate instruction classroom in the library.

DNA incisions stimulate genetic instability of triplet repeat sequences related to human hereditary neurological diseases

The molecular mechanisms responsible for the expansion and deletion of trinucleotide repeat sequences (TRS) are the focus of our studies. Several hereditary neurological diseases including Huntington's disease, myotonic dystrophy, and fragile X syndrome are associated with the instability of TRS. Using the well defined and controllable model system of Escherichia coli, the influences of three types of DNA incisions on genetic instability of CTG•CAG repeats were studied: DNA double-strand breaks (DSB), single-strand nicks, and single-strand gaps. The DNA incisions were generated in pUC19 derivatives by in vitro cleavage with restriction endonucleases. The cleaved DNA was then transformed into E. coli parental and mutant strains. Double-strand breaks induced deletions throughout the TRS region in an orientation dependent manner relative to the origin of replication. The extent of instability was enhanced by the repeat length and sequence (CTG•CAG vs. CGG•CCG). Mutations in recA and recBC increased deletions, mutations in recF stabilized the TRS, whereas mutations in ruvA had no effect. DSB were repaired by intramolecular recombination, versus an intermolecular gene conversion or crossover mechanism. 30 nt gaps formed a distinct 30 nt deletion product, whereas single strand nicks and gaps of 15 nts did not induce expansions or deletions. Formation of this deletion product required the CTG•CAG repeats to be present in the single-stranded region and was stimulated by E. coli DNA ligase, but was not dependent upon the RecFOR pathway. Models are presented to explain the DSB induced instabilities and formation of the 30 nucleotide deletion product. In addition to the in vitro creation of DSBs, several attempts to generate this incision in vivo with the use of EcoR I restriction modification systems were conducted. ^

Counts of benthos communities in Kongsfjorden in 2009

In order to reveal the structure of the sparsely known deeper sublittoral hard bottom communities of glacial Kongsfjorden, the macroepibenthos from six depth zones (30-200 m) was analysed. A total of 180 still images derived from 6-h video recorded at the Kongsfjordneset remotely operated vehicle station were assessed quantitatively. Overall 27 mainly suspension-feeding species/taxa were observed. Of these, two-thirds have an arcto-boreal distribution, while the remainder are cosmopolitan. The overall mean epibenthos abundance was 33 ind./m**2 with maximum values at 150 m depth (97.9 ind./m**2). The majority of the taxa inhabited the entire depth range. Encrusting red algae, an unidentified sponge and the sea anemone Urticina eques, characterized the assemblage of the shallow zone. The sea anemones Hormathia spp. were important below 30 m, the Serpulid polychaete Protula tubularia was characteristic for the community below 50 m and the demosponge Haliclona sp. was a key taxon between 100 and 200 m depth. Cluster analysis and non-metrical multidimensional scaling based on abundance data showed differences between the assemblages along the bathymetric gradient, but only in the shallower depths in relation to the substratum surface incline. As surface and tidal current impacts attenuate with increasing depth, there is a gradual trend from robust key species towards more fragile ones (i.e. P. tubularia), in line with the 'Physical control hypothesis'.

El ordenamiento territorial en Argentina : editorial

La Revista Proyección dedica este número a presentar estudios realizados en distintas provincias argentinas luego de la crisis económica del año 2001. Muestran el estado de situación actual y plantean la necesidad del Ordenamiento Territorial para poder superar algunos de los efectos que provoca el modelo neoliberal instaurado a principios de los ’90: desequilibrios territoriales, crecimiento urbano sin control, pérdida permanente y progresiva de capital natural, cultural y social, conflictos sociales.

Tratamiento de superficie de las restauraciones de porcelana feldespática y su implicancia en la propagación de las fallas estructurales propias del material

Durante el proceso de elaboración de las porcelanas feldespáticas se producen en su interior micro rajaduras las cuales se propagan a través de la matriz vítrea aumentando la fragilidad del material cuando se lo expone a los esfuerzos mecánicos. Las restauraciones rígidas de porcelanas feldespáticas son sometidas a distintos tratamientos en su superficie para aumentar la adhesión a las estructuras dentarias cuando son cementadas. Estos tratamientos son acondicionamiento con ácido fluorhídrico y microarenado. Objetivos de este trabajo: 1. Evaluar la resistencia flexural de este material mediante ensayo mecánico en máquina Instron, previo tratamiento en su superficie con ácido fluorhídrico y microarenado. 2. Observar al MEB las alteraciones de superficie producidas por el microarenado y el ácido fluorhídrico. Los resultados obtenidos demostraron que el tratamiento de microarenado produjo una reducción de la resistencia flexural. El MEB confirmó la presencia de mayor cantidad de microgrietas que podrían ser responsables de la disminución de la resistencia flexural.

El camino recorrido por la concepción de desarrollo : Discusiones y prácticas

Relevar y evidenciar aspectos vinculados con el concepto de desarrollo puede permitir aprehender sus áreas imprecisas e incongruentes. La noción ha resultado una fuerza directriz sobre el pensamiento occidental a la vez que el núcleo de una constelación semántica a través de la cual las personas piensan, sienten y actúan. De este modo, al constituir un significante quereúne elementos heterogéneos, puede ejercer atracción sobre demandas sociales insatisfechas y en relación con interrogantes de investigación en disciplinas sociales. Sin embargo, bajo su denominación suelen albergarse ideas diversas, cambiantes y hasta contradictorias. Frente a su supuesta fortaleza, pocas palabras pueden resultar tan vagas, frágiles e incapaces de ofrecer sustancia y significado. Considerando esto, pretendemos describir y analizar el desarrollo en tanto concepción, concepto y práctica, con el objetivo de aportar al cuestionamiento de sus preceptos básicos y replantear nuestra práctica en tanto investigadores.

Degradación de la tierra en un sector de la estepa patagónica en la provincia de Neuquén

En este trabajo se analiza la relación entre degradación y el uso y manejo de la tierra para ganadería extensiva, de acuerdo al tipo de tenencia de la tierra. El sector elegido se localiza al Oeste de la localidad de las Coloradas, Departamento Catan Lil en la provincia de Neuquén, y comprende una superficie de 9.000 ha; una parte de la misma corresponde a un campo privado y el resto a un sector fiscal ocupado por crianceros. La elección del área de estudio se justifica en el hecho de que este departamento es uno de los más pobres y frágiles de la provincia en cuanto a la potencialidad del ecosistema para uso ganadero y en que en él se dan los distintos tipos de tenencia de la tierra, tanto fiscal como privada y de comunidades indígenas. En el caso de este estudio, se considera un sector ocupado por un campo privado y el resto por crianceros. Del análisis realizado surge que la dinámica y evolución del paisaje responde a las formas de manejo de acuerdo al tipo de tenencia de la tierra.

El camino recorrido por la concepción de desarrollo : Discusiones y prácticas

Relevar y evidenciar aspectos vinculados con el concepto de desarrollo puede permitir aprehender sus áreas imprecisas e incongruentes. La noción ha resultado una fuerza directriz sobre el pensamiento occidental a la vez que el núcleo de una constelación semántica a través de la cual las personas piensan, sienten y actúan. De este modo, al constituir un significante quereúne elementos heterogéneos, puede ejercer atracción sobre demandas sociales insatisfechas y en relación con interrogantes de investigación en disciplinas sociales. Sin embargo, bajo su denominación suelen albergarse ideas diversas, cambiantes y hasta contradictorias. Frente a su supuesta fortaleza, pocas palabras pueden resultar tan vagas, frágiles e incapaces de ofrecer sustancia y significado. Considerando esto, pretendemos describir y analizar el desarrollo en tanto concepción, concepto y práctica, con el objetivo de aportar al cuestionamiento de sus preceptos básicos y replantear nuestra práctica en tanto investigadores.

Degradación de la tierra en un sector de la estepa patagónica en la provincia de Neuquén

En este trabajo se analiza la relación entre degradación y el uso y manejo de la tierra para ganadería extensiva, de acuerdo al tipo de tenencia de la tierra. El sector elegido se localiza al Oeste de la localidad de las Coloradas, Departamento Catan Lil en la provincia de Neuquén, y comprende una superficie de 9.000 ha; una parte de la misma corresponde a un campo privado y el resto a un sector fiscal ocupado por crianceros. La elección del área de estudio se justifica en el hecho de que este departamento es uno de los más pobres y frágiles de la provincia en cuanto a la potencialidad del ecosistema para uso ganadero y en que en él se dan los distintos tipos de tenencia de la tierra, tanto fiscal como privada y de comunidades indígenas. En el caso de este estudio, se considera un sector ocupado por un campo privado y el resto por crianceros. Del análisis realizado surge que la dinámica y evolución del paisaje responde a las formas de manejo de acuerdo al tipo de tenencia de la tierra.

El camino recorrido por la concepción de desarrollo : Discusiones y prácticas

Relevar y evidenciar aspectos vinculados con el concepto de desarrollo puede permitir aprehender sus áreas imprecisas e incongruentes. La noción ha resultado una fuerza directriz sobre el pensamiento occidental a la vez que el núcleo de una constelación semántica a través de la cual las personas piensan, sienten y actúan. De este modo, al constituir un significante quereúne elementos heterogéneos, puede ejercer atracción sobre demandas sociales insatisfechas y en relación con interrogantes de investigación en disciplinas sociales. Sin embargo, bajo su denominación suelen albergarse ideas diversas, cambiantes y hasta contradictorias. Frente a su supuesta fortaleza, pocas palabras pueden resultar tan vagas, frágiles e incapaces de ofrecer sustancia y significado. Considerando esto, pretendemos describir y analizar el desarrollo en tanto concepción, concepto y práctica, con el objetivo de aportar al cuestionamiento de sus preceptos básicos y replantear nuestra práctica en tanto investigadores.

Degradación de la tierra en un sector de la estepa patagónica en la provincia de Neuquén

En este trabajo se analiza la relación entre degradación y el uso y manejo de la tierra para ganadería extensiva, de acuerdo al tipo de tenencia de la tierra. El sector elegido se localiza al Oeste de la localidad de las Coloradas, Departamento Catan Lil en la provincia de Neuquén, y comprende una superficie de 9.000 ha; una parte de la misma corresponde a un campo privado y el resto a un sector fiscal ocupado por crianceros. La elección del área de estudio se justifica en el hecho de que este departamento es uno de los más pobres y frágiles de la provincia en cuanto a la potencialidad del ecosistema para uso ganadero y en que en él se dan los distintos tipos de tenencia de la tierra, tanto fiscal como privada y de comunidades indígenas. En el caso de este estudio, se considera un sector ocupado por un campo privado y el resto por crianceros. Del análisis realizado surge que la dinámica y evolución del paisaje responde a las formas de manejo de acuerdo al tipo de tenencia de la tierra.

Silicoflagellates and ebridians from ODP Leg 138 holes

The biostratigraphic distribution and abundance of middle Miocene to Pleistocene silicoflagellates is documented from Ocean Drilling Program (ODP) Leg 138 Holes 844B, 847B, 848B, 849B, 850B, 85 IB, 852B, and 854B from the eastern Equatorial Pacific Ocean. The silicoflagellates were generally abundant and well preserved and frequently exhibited an unusually large range of variation. The upper Miocene of near-equatorial sites includes an assemblage of Bachmannocena diodon nodosa, which includes a bridge across the width of the basal ring. Stratigraphically below this, at sites within 5° of the equator is a lengthy interval of specimens of Distephanus speculum tenuis, which have a fragile apical structure. Both the intervals of Bachmannocena diodon nodosa plexus and Distephanus speculum tenuis are biostratigraphically useful within 5° of the equator, but are less useful beyond that. An unusual range of variation also is observed for Dictyocha in the Pliocene sediments at about the point where D. perlaevis and D. messanensis appear in the geologic record. This variation may be explained by hybridization between diverging species.