Sevoflurano e desflurano sobre o ritmo cardíaco de cães tratados com infusão contínua de doses crescentes de adrenalina

Os anestésicos inalatórios sensibilizam o miocárdio ou seu sistema de condução à ação das catecolaminas endógenas e/ou exógenas, predispondo o animal às arritmias cardíacas. Dentre os anestésicos voláteis, o sevoflurano e o desflurano são fármacos relativamente recentes e, embora sejam dotados de características relacionadas a não sensibilização do miocárdio às catecolaminas, desconhecem-se estudos que comparem suas eventuais propriedades antiarritmogênicas. Com o objetivo de estudar, comparativamente, o comportamento do ritmo cardíaco e observar eventuais bloqueios atrioventriculares em cães anestesiados pelo sevoflurano e desflurano e submetidos à infusão contínua de adrenalina, foram utilizados 20 animais adultos, os quais foram separados em dois grupos de igual número (G1 e G2). Aos cães do G1, foi administrado propofol, na dose média de 10mmg.kg-1; em seguida os animais receberam sevoflurano, a 1,5CAM. Decorridos 30 minutos do início da administração do anestésico volátil, iniciou-se a infusão de adrenalina na dose de 1mmg.kg-1.min-1. A cada 10 minutos, a dose da catecolamina foi acrescida em uma unidade, cessando-se a administração em 6mmg.kg-1.min-1. Para o G2, empregou-se a mesma metodologia, substituindo-se o sevoflurano pelo desflurano, administrado a 1,5CAM. A cada dose de adrenalina, foi feita contagem de batimentos ventriculares ectópicos, bem como a observação de bloqueios atrioventriculares. Os achados foram tratados pelos métodos estatísticos de Análise de Perfil e Kruskall-Wallis. Os resultados permitiram concluir que o desflurano minimiza de maneira mais eficiente a arritmia induzida pela adrenalina, além de reduzir a incidência de bloqueios atrioventriculares.

Diretrizes para desenvolvimento coletivo de melhoria contínua em arranjos produtivos locais

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Capacidade de suporte de pastagens de capim-tifton 85 adubado com nitrogênio manejadas em lotação contínua com ovinos

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Efeitos de diferentes frações inspiradas de oxigênio sobre a dinâmica respiratória em cães submetidos à infusão contínua de propofol e mantidos em ventilação espontânea

The effects of several inspired oxygen fractions (FiO 2) on the respiratory dynamics in spontaneously breathing dogs submitted to continuous infusion of propofol were evaluated. Eight adult mongrel dogs were used. Each animal underwent five anesthesias, in each procedure the patient was allowed to breath a different FiO 2, thereby resulting in five groups, namely: G100 (FiO 2 = 1), G80 (FiO 2 = 0.8), G60 (FiO 2 =0.6), G40 (FiO 2 = 0.4), and G20 (FiO 2 = 0.21). To induce anesthesia, propofol was given until the animals allowed orotracheal intubation, followed by immediate continuous infusion of drug. The initial measurement (M0) was recorded thirty minutes after the infusion of propofol has begun. Additional recordings were performed at 15 minute intervals for 60 minutes (M15, M30, M45 and M60). Numeric data were submitted to Analysis of Variance followed by Tukey Test (p<0.05). We recorded significantly lower values of SpO 2 and SaO 2 at G20, whereas PaO 2 varied according to the changes in oxygen. Regarding PaCO 2, the mean of G100 was greater than G20 at M30. However, spontaneously breathing dogs anesthetized with propofol at the rate of 0.7mg/kg/min should not be provided with 100%, 80%, and 21% oxygen owing to the significant compromise of respiratory system.

Raquianestesia contínua em paciente submetido à gastrectomia parcial. Relato de caso

BACKGROUND AND OBJECTIVES: Due to the high incidence of technical and neurological complications, continuous spinal blocks were not performed for several years. With the advent of intermediate catheters the technique has been used more often and gaining acceptance among anesthesiologists. The objective of this report was to demonstrate the usefulness of the technique as a viable alternative for medium and major size surgeries. CASE REPORT: This is a 58 years old female patient, weighing 62 kg, physical status ASA I, with a history of migraines, low back pain, and prior surgeries under spinal block without intercurrence. The patient was scheduled for exploratory laparotomy for a probable pelvic tumor. After venoclysis with an 18G catheter, monitoring with cardioscope, non-invasive blood pressure and pulse oximetry was instituted; she was sedated with 2 mg of midazolam and 100 μg of fentanyl, and placed in left lateral decubitus. The patient underwent continuous spinal block through the median approach in L 3-L 4; 9 mg of 0.5% hyperbaric bupivacaine and 120 μ g of morphine sulfate were administered. Inspection of the abdominal cavity revealed a gastric stromal tumor that required an increase in the incision for a partial gastrectomy. A small dose of hyperbaric solution was required for the entire procedure, which was associated with complete hemodynamic stability. Postoperative admission to the ICU was not necessary; the patient presented a good evolution without complaints and with a high degree of satisfaction. She was discharged from the hospital after 72 hours without intercurrence. CONCLUSIONS: Intermediate catheters used in continuous spinal blocks have shown the potential to turn it an attractive and useful technique in medium and large size surgeries and it can even be an effective alternative in the management of critical patients to whom hemodynamic repercussions can be harmful.

Número de perfilhos do capim-braquiária em regime de lotação contínua

The study was conducted to identify, through assessments of tillering, appropriate management strategies for Brachiaria decumbens cv. Basilisk under continuous stocking with cattle. Two management strategies were studied: pasture with 25 cm throughout the experimental period, and pasture with 15 cm in winter and 25 cm in spring and summer. A split-plot and randomized block design with four replications were adopted. The management strategies represented the primary factor, and the seasons (winter, spring and summer) were the secondary factor. The lowest balance between rates of appearance (TAR) and mortality (TMR) of tillers and the lowest number of vegetative tillers occurred in winter. In spring and summer, the balance and number of vegetative tillers were higher and did not differ. The lowering of pasture in winter resulted in greater balance between TAR and TMR and higher number of tillers in relation to management on sward fixed at 25 cm. There were greater numbers of reproductive and dead tillers in summer and winter, respectively. The pastures with fixed height of 25 cm contained a higher number of dead tiller. Under continuous stocking, the lowering of B. decumbens pasture in winter and its increase to 25 cm in spring and summer optimizes turnover of tillers.

Produção de forragem de Tifton 85 adubado com nitrogênio e submetido à lotação contínua

The present assay was conducted at the Research and Development of Adamantina, SP, of the Agência Paulista de Tecnologia dos Agronegócios (APTA) - Pólo da Alta Paulista to evaluate the effect of nitrogen fertilization on morphological composition, density of tillers, leaf area index, light interception and herbage accumulation in grazed Tifton 85 subjected to continuous stocking system. The treatments consisted of four levels of nitrogen (0; 100; 200 and 400kg/ha/year of N), arranged in a randomized complete blocks experimental design with four replications. The grasslands of Cynodon cv. Tifton 85 studied influenced the time of evaluation and of nitrogen levels with a marked effect in morphological composition of the pasture, leaf area index, light interception and population density of tillers that were instrumental in the accumulation of forage. It was found a positive linear effect of nitrogen fertilization on the density of vegetative tillers, totals and herbage accumulation nitrogen fertilization had a marked effect on the amount of total and vegetative tillers, leaf area index in light interception and herbage accumulation. The cultivar Tifton 85 has not reached the necessary conditions for crop growth rate maximum when managed under continuous stocking keeping the grass to 10cm tall.

Efeito da corrente elétrica contínua isolada e da iontoforese transdermal, associada ao zinco, sobre a resistência mecânica e o conteúdo de hidroxiprolina de cicatrizes realizadas na pele de ratos diabéticos aloxânicos

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Efeitos do citrato de sufentanil, administrado em infusão contínua, na concentração alveolar mínima (CAM) de isofluorano em felinos

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Experiências de educadores: convite para reflexão sobre a formação contínua

Pós-graduação em Artes - IA

Atividade eletromiográfica dos músculos eretores da espinha durante contração isométrica contínua em diferentes níveis de carga: efeito de um protocolo de treinamento de resistência isométrica

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Respostas metabólicas e da técnica de nado durante o exercício realizado na velocidade correspondente à máxima fase estável de lactato sanguíneo determinada de forma contínua e intermitente

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Efeitos cardiorrespiratórios e motilidade gastrointestinal da infusão contínua de butorfanol em equinos anestesiados pelo isofluorano

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Parâmetros ventilométricos, cardiovasculares, hematológicos e índice biespectral, em cães anestesiados com infusão contínua de propofol, associado ou não ao tramadol

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Infusão contínua de morfina ou fentanil, associados à licodaína e cetamina, em cães anestesiados com isofluorano

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)