Manuscript copy of the book of Harvard, 1767

Handwritten copy of the Book of Harvard written on one large sheet of paper and signed Boston, January 10th, 1767.

Collection of humorous verses and sketches relating to Harvard College, 1769

Manuscript volume in various hands containing three general sections: satirical poems about Harvard tutors, a section of "last words & dying" speeches of Harvard tutors, and a copy of the Book of Harvard."

Commonplace book of Clement Weeks

Commonplace book containing a transcription of the "The Book of Harvard," a satirical account of the Butter Rebellion of 1766 followed with supplementary text of "The Arguments in Defence of the Proceedings of the Scholars" and "The Confession that was made after all was done." The above occupies pp. 1-14; pp. 15-18 missing. Pages 19-23 hold excerpts from Edward Young's Conjectures on Original Composition. Pages 24-62 hold excerpts from Saint Augustine's Heresies. Finally pages 62-64 hold an excerpt of Druidical maxims from the introduction of the first volume of Paul Rapin de Thoyras' The History of England (1724).

Historic Letter Collection, 1796-1940 (inclusive). 1844-1872. Joseph Dalton Hooker letters, 1844-1872

Historic Letter Collection, 1796-1940; Joseph Dalton Hooker letters, 1844-1872. HL Hook 1-3. Gray Herbarium Archives, Harvard University, Cambridge, Mass.

Doença inflamatória intestinal associada a colangite esclerosante primária : um fenótipo raro

Trabalho Final do Curso de Mestrado Integrado em Medicina, Faculdade de Medicina, Universidade de Lisboa, 2014

Human naïve regulatory T-cells feature high steady-state turnover and are maintained by IL-7

Naïve FoxP3-expressing regulatory T-cells (Tregs) are essential to control immune responses via continuous replenishment of the activated-Treg pool with thymus-committed suppressor cells. The mechanisms underlying naïve-Treg maintenance throughout life in face of the age-associated thymic involution remain unclear. We found that in adults thymectomized early in infancy the naïve-Treg pool is remarkably well preserved, in contrast to conventional naïve CD4 T-cells. Naïve-Tregs featured high levels of cycling and pro-survival markers, even in healthy individuals, and contrasted with other circulating naïve/memory CD4 T-cell subsets in terms of their strong γc-cytokine-dependent signaling, particularly in response to IL-7. Accordingly, ex-vivo stimulation of naïve-Tregs with IL-7 induced robust cytokine-dependent signaling, Bcl-2 expression, and phosphatidylinositol 3-kinase (PI3K)-dependent proliferation, whilst preserving naïve phenotype and suppressive capacity. Altogether, our data strongly implicate IL-7 in the thymus-independent long-term survival of functional naïve-Tregs, and highlight the potential of targeting the IL-7 pathway to modulate Tregs in different clinical settings.

Greater Europe. Putin's vision of European (dis)integration. OSW Study 46/2013

On several occasions since 2001 Vladimir Putin has raised the concept of ‘Greater Europe’, a partly-integrated common space comprising mainly Russia and the European Union. This concept has never been recast into a detailed political programme. While it has been championed as‘a Europe without dividing lines’, the concept would in practice permanently split Europe into two geopolitical blocs – the Western bloc of the European Union, with Germany in the dominant role, and the Eastern bloc, consisting of the emerging Eurasian Union, with Russia in a hegemonic position. In recent years Russia has undertaken a number of initiatives aimed at implementing some elements of the concept. However, most of these have failed to become reality. In this context, we should expect Russia’s policy to focus on implementing its priority project of Eurasian integration, based on the structures of the Customs Union/the Eurasian Union. The Greater Europe project, on the other hand, will be postponed until the time when, as Moscow believes, a weakened EU will be ready to accept Russian proposals.

Proglacial river dataset from the Akuliarusiarsuup Kuua River northern tributary, Southwest Greenland, 2008 - 2010, version 1.0

Pressing scientific questions concerning the Greenland ice sheet's climatic sensitivity, hydrology, and contributions to current and future sea level rise require hydrological datasets to resolve. While direct observations of ice sheet meltwater losses can be obtained in terrestrial rivers draining the ice sheet and from lake levels, few such datasets exist. We present a new dataset of meltwater river discharge for the vicinity of Kangerlussuaq, Southwest Greenland. The dataset contains measurements of river stage and discharge for three sites along the Akuliarusiarsuup Kuua (Watson) River's northern tributary, with 30 minute temporal resolution between June 2008 and August 2010. Additional data of water temperature, air pressure, and lake water depth and temperature are also provided. Discharge data were measured at sites with near-ideal properties for such data collection. Regardless, high water bedload and turbulent flow introduce considerable uncertainty. These were constrained and quantified using statistical techniques, thereby providing a high quality dataset from this important site. The greatest data uncertainties are associated with streambed elevation change and measurements. Large portions of stream channels deepened according to statistical tests, but poor precision of streambed depth measurements also added uncertainty. Quality checked data are freely available for scientific use as supplementary online material.

Synoptical flora of North America /

Vol. I. pt. II. Caprifollaceæ to Compositæ first published in 1884; vol. II. pt. I, Gamopetalæ after Composilæ, in 1878.

First lessons in botany and vegetable physiology : illustrated by over 360 wood engravings from original drawings by Isaac Sprague : to which is added a copious glossary, or dictionary of botanical terms /

Mode of access: Internet.

The best books of the decade,

Mode of access: Internet.

Reports of cases argued and determined in the Superior Court of Judicature for the State of New-Hampshire.

Imprint varies: Concord, N.H., -1841/42.

Reports of cases in the Superior Court of Judicature of New-Hampshire.

Vol. 13-18 called also 2nd ser., v. 1-6.

The most important parts of Blackstone's Commentaries : reduced to questions and answers /

Mode of access: Internet.