738 resultados para Annotation de génomes


Relevância:

10.00% 10.00%

Publicador:

Resumo:

With Japanese annotation.

Relevância:

10.00% 10.00%

Publicador:

Resumo:

Illustrated with reproduction of a drawing of a female nude, p. [2] of cover.

Relevância:

10.00% 10.00%

Publicador:

Resumo:

Mode of access: Internet.

Relevância:

10.00% 10.00%

Publicador:

Resumo:

Annotation: marginalia in unknown hand.

Relevância:

10.00% 10.00%

Publicador:

Resumo:

(Annotation on back says Sept. 1937)

Relevância:

10.00% 10.00%

Publicador:

Resumo:

[annotation on verso: [Perry on his way for a TD after a long run."]

Relevância:

10.00% 10.00%

Publicador:

Resumo:

[annotation on back is "Wakabayashi"]

Relevância:

10.00% 10.00%

Publicador:

Resumo:

[annotation on verso: "Willie Heston, 20-yard run against Chicago, 1903 -- Eckersall at far right."]

Relevância:

10.00% 10.00%

Publicador:

Resumo:

Heft 2 contains an unnumbered signature, separately paged (1-11), cntaining: I, Verzeichnis der anzuwendenden abkürzungen der autoren (p. [1]-6); II, Verzeichnis der abkürzungen für die haüfiger benutzten zeitschriften nebst beispielen für die angabe der bände und seitenzahlen (p. [7]-9); III, Verzeichnis der abkürzungen für einige hauptwerke nebst biespielen für die angabe der bände und seitenzahlen (p. [10]-11)

Relevância:

10.00% 10.00%

Publicador:

Resumo:

Thesis (Ph.D.)--University of Washington, 2016-06

Relevância:

10.00% 10.00%

Publicador:

Resumo:

The chromodomain is 40-50 amino acids in length and is conserved in a wide range of chromatic and regulatory proteins involved in chromatin remodeling. Chromodomain-containing proteins can be classified into families based on their broader characteristics, in particular the presence of other types of domains, and which correlate with different subclasses of the chromodomains themselves. Hidden Markov model (HMM)-generated profiles of different subclasses of chromodomains were used here to identify sequences encoding chromodomain-containing proteins in the mouse transcriptome and genome. A total of 36 different loci encoding proteins containing chromodomains, including 17 novel loci, were identified. Six of these loci (including three apparent pseudogenes, a novel HP1 ortholog, and two novel Msl-3 transcription factor-like proteins) are not present in the human genome, whereas the human genome contains four loci (two CDY orthologs and two apparent CDY pseuclogenes) that are not present in mouse. A number of these loci exhibit alternative splicing to produce different isoforms, including 43 novel variants, some of which lack the chromodomain. The likely functions of these proteins are discussed in relation to the known functions of other chromodomain-containing proteins within the same family.

Relevância:

10.00% 10.00%

Publicador:

Resumo:

With the completion of the human and mouse genome sequences, the task now turns to identifying their encoded transcripts and assigning gene function. In this study, we have undertaken a computational approach to identify and classify all of the protein kinases and phosphatases present in the mouse gene complement. A nonredundant set of these sequences was produced by mining Ensembl gene predictions and publicly available cDNA sequences with a panel of InterPro domains. This approach identified 561 candidate protein kinases and 162 candidate protein phosphatases. This cohort was then analyzed using TribeMCL protein sequence similarity clustering followed by CLUSTALV alignment and hierarchical tree generation. This approach allowed us to (1) distinguish between true members of the protein kinase and phosphatase families and enzymes of related biochemistry, (2) determine the structure of the families, and (3) suggest functions for previously uncharacterized members. The classifications obtained by this approach were in good agreement with previous schemes and allowed us to demonstrate domain associations with a number of clusters. Finally, we comment on the complementary nature of cDNA and genome-based gene detection and the impact of the FANTOM2 transcriptome project.

Relevância:

10.00% 10.00%

Publicador:

Resumo:

The number of known mRNA transcripts in the mouse has been greatly expanded by the RIKEN Mouse Gene Encyclopedia project. Validation of their reproducible expression in a tissue is an important contribution to the study of functional genomics. In this report, we determine the expression profile of 57,931 clones on 20 mouse tissues using cDNA microarrays. Of these 57,931 clones, 22,928 clones correspond to the FANTOM2 clone set. The set represents 20,234 transcriptional units (TUs) out of 33,409 TUs in the FANTOM2 set. We identified 7206 separate clones that satisfied stringent criteria for tissue-specific expression. Gene Ontology terms were assigned for these 7206 clones, and the proportion of 'molecular function' ontology for each tissue-specific clone was examined. These data will provide insights into the function of each tissue. Tissue-specific gene expression profiles obtained using our cDNA microarrays were also compared with the data extracted from the GNF Expression Atlas based on Affymetrix microarrays. One major outcome of the RIKEN transcriptome analysis is the identification of numerous nonprotein-coding mRNAs. The expression profile was also used to obtain evidence of expression for putative noncoding RNAs. In addition, 1926 clones (70%) of 2768 clones that were categorized as unknown EST, and 1969 (58%) clones of 3388 clones that were categorized as unclassifiable were also shown to be reproducibly expressed.