909 resultados para Age-of-onset


Relevância:

100.00% 100.00%

Publicador:

Resumo:

"An appeal on behalf of the Oberlin institute": p. [v]-xix.

Relevância:

100.00% 100.00%

Publicador:

Resumo:

Reprinted in part from McClure's magazine.

Relevância:

100.00% 100.00%

Publicador:

Resumo:

Mode of access: Internet.

Relevância:

100.00% 100.00%

Publicador:

Resumo:

Introduction. - Sir Henry Bessemer. - Sir William Siemens. - Sir Joseph Whitworth. - Sir John Brown. - Mr. S.G. Thomas. - Mr. G.J. Snelus.

Relevância:

100.00% 100.00%

Publicador:

Resumo:

Mode of access: Internet.

Relevância:

100.00% 100.00%

Publicador:

Resumo:

Mode of access: Internet.

Relevância:

100.00% 100.00%

Publicador:

Resumo:

"First published 1895; reprinted 1897 ... 1920."

Relevância:

100.00% 100.00%

Publicador:

Resumo:

"These essays...were originally delivered as lectures before the Lowell Institute, in the spring of 1859, and were first printed in the Atlantic monthly during the years 1867 and 1868."

Relevância:

100.00% 100.00%

Publicador:

Resumo:

Mode of access: Internet.

Relevância:

100.00% 100.00%

Publicador:

Resumo:

Originally presented as the author's thesis (Ph. D.)--Yale.

Relevância:

100.00% 100.00%

Publicador:

Resumo:

Himalayan adventure travel is a burgeoning industry in some mountainous regions of Nepal, India, and the Tibet Autonomous Region of the People‘s Republic of China. The development of a trekking and expedition mountaineering infrastructure has created economic opportunities in remote areas and allowed foreign visitors to embark on life-changing explorations. However, with the industry’s rapid, uneven, and largely unregulated growth have come environmental and resource challenges, the creation of new economic and social arrangements, and renewed questions of equity and safety. The current Himalayan adventure travel paradigm is unsustainable, and I argue that only a profound reimagining of sociopolitical relationships—those between the state, local and global civil society actors, and adventure travel practitioners and participants—will allow it to continue. A series of recent disasters in the mountains may serve as the necessary catalyst for previously underrepresented stakeholders to translate their growing assertiveness into meaningful and durable solutions.

Relevância:

100.00% 100.00%

Publicador:

Resumo:

Migraine is a common complex disorder characterized by severe recurrent headache and usually accompanied by nausea and vomiting. Previous studies in our laboratory have utilized three large multigenerational Australian pedigrees affected with migraine to indicate that the disease is genetically heterogeneous, with linkage results implicating genomic susceptibility regions on both chromosomes 19p and Xq. The present study explores the possibility of a correlation between genetic and clinical heterogeneity in these affected pedigrees. Specifically, the clinical characteristics of migraine including subtype, age of onset, frequency, duration, and disease symptoms were compared between the migraine pedigrees, and gender differences were also assessed. Our exploratory analyses revealed no significant differences in any of the clinical characteristics tested between the chromosome 19-linked family and the two X-linked families. Also, we did not detect any differences in male vs. female clinical features for these pedigrees. In conclusion, migraine is considered to be a clinically and genetically heterogeneous disorder; however, our study provided no conclusive evidence that variation in genomic susceptibility region is related to heterogeneity at the clinical level in these migraine-affected pedigrees.

Relevância:

100.00% 100.00%

Publicador:

Resumo:

Background: Previous research into age of onset in affective disorders has produced conflicting results. This paper examines the influence of heterogeneity on the age-at-first-registration distribution for the ICD-9 diagnostic group 'affective psychosis'. Method: For 1979-1991, data for age-at-first-registration for 4985 individuals diagnosed with affective psychosis (ICD-9 296.x) were extracted from a name-linked mental health register. These data were divided into (i) '296.1 only', a category used to code unipolar depression (males = 700; females = 1321); and (ii) '296 other', all 296 cases other than 296.1 (males = 1280; females = 1684). Inception rates for each 5-year age division were adjusted for the background population age-structure as a rate per 100 000 population. Results: The age-at-first-registration distribution for affective psychosis has a wide age range, with women outnumbering men. There is a near-linear increase in inception rates for both men and women with 296.1 only, while the bulk of those with affective psychoses (296 other) have an inverted U-shaped age distribution. Males have an earlier modal age-at-first-registration for 296 other compared to females. Conclusion: The heterogeneity in terms of subtypes and sex in affective psychosis clouds the interpretation of age-at-first-registration. Separating those with unipolar psychotic depression from other subclassifications and differentiating by sex may provide clues to factors that precipitate the onset of affective psychosis.