836 resultados para Age factors in disease.
Resumo:
Interface discontinuity factors based on the Generalized Equivalence Theory are commonly used in nodal homogenized diffusion calculations so that diffusion average values approximate heterogeneous higher order solutions. In this paper, an additional form of interface correction factors is presented in the frame of the Analytic Coarse Mesh Finite Difference Method (ACMFD), based on a correction of the modal fluxes instead of the physical fluxes. In the ACMFD formulation, implemented in COBAYA3 code, the coupled multigroup diffusion equations inside a homogenized region are reduced to a set of uncoupled modal equations through diagonalization of the multigroup diffusion matrix. Then, physical fluxes are transformed into modal fluxes in the eigenspace of the diffusion matrix. It is possible to introduce interface flux discontinuity jumps as the difference of heterogeneous and homogeneous modal fluxes instead of introducing interface discontinuity factors as the ratio of heterogeneous and homogeneous physical fluxes. The formulation in the modal space has been implemented in COBAYA3 code and assessed by comparison with solutions using classical interface discontinuity factors in the physical space
Resumo:
ABSTRACT: Transcription factors (TFs) are proteins that have played a central role both in evolution and in domestication, and are major regulators of development in living organisms. Plant genome sequences reveal that approximately 7% of all genes encode putative TFs. The DOF (DNA binding with One Finger) TF family has been associated with vital processes exclusive to higher plants and to their close ancestors (algae, mosses and ferns). These are seed maturation and germination, light-mediated regulation, phytohormone and plant responses to biotic and abiotic stresses, etc. In Hordeum vulgare and Oryza sativa, 26 and 30 different Dof genes, respectively, have been annotated. Brachypodium distachyon has been the first Pooideae grass to be sequenced and, due to its genomic, morphological and physiological characteristics, has emerged as the model system for temperate cereals, such as wheat and barley. RESULTS: Through searches in the B. distachyon genome, 27 Dof genes have been identified and a phylogenetic comparison with the Oryza sativa and the Hordeum vulgare DOFs has been performed. To explore the evolutionary relationship among these DOF proteins, a combined phylogenetic tree has been constructed with the Brachypodium DOFs and those from rice and barley. This phylogenetic analysis has classified the DOF proteins into four Major Cluster of Orthologous Groups (MCOGs). Using RT-qPCR analysis the expression profiles of the annotated BdDof genes across four organs (leaves, roots, spikes and seeds) has been investigated. These results have led to a classification of the BdDof genes into two groups, according to their expression levels. The genes highly or preferentially expressed in seeds have been subjected to a more detailed expression analysis (maturation, dry stage and germination). CONCLUSIONS: Comparison of the expression profiles of the Brachypodium Dof genes with the published functions of closely related DOF sequences from the cereal species considered here, deduced from the phylogenetic analysis, indicates that although the expression profile has been conserved in many of the putative orthologs, in some cases duplication followed by subsequent divergence may have occurred (neo-functionalization).
Resumo:
Las biomasas almacenadas en silos son potencialmente capaces de absorber oxígeno produciendo reacciones exotérmicas de oxidación. Si el calor producido en estas reacciones no se dispersa adecuadamente, provoca un auto-calentamiento de la materia orgánica que puede ser causa de descomposición e inflamación. En el ámbito de la posible auto-combustión en el almacenamiento y manipulación de las biomasas existen diversos factores que influyen en la susceptibilidad térmica de las biomasas, es decir, en su tendencia a la oxidación y posterior inflamación de la materia. Con el fin de analizar este comportamiento se han estudiado diferentes tipos de biomasas. En este estudio se ha trabajado con biomasas de origen agrícola, forestal y residual con distinta composición química. Las muestras de estudio se han acondicionado mediante distintos tratamientos físicos para valorar la influencia de diferentes factores en su auto-combustión.
Resumo:
This paper analyzed the building techniques based in the use of rammed earth in the Late Medieval fortifications in the province of Soria, Spain. The manorial castles of Serón de Nágima and Yanguas were built completely with rammed earth. However, these techinques are different. Through the study of the constructive signals, we can reconstruct the constructive process and made an hypothesis of the auxiliary scaffolding necessary for the construction. After, other four cases in which there is presence of rammed earth are described: Ágreda, Arcos de Jalón, Caracena and the tower of Martín González or castle of La Raya (the Border). Rammed earth is used in some secondary architectural elements and also as a filling of the masonry walls, but somtimes there are ancient rammed earth walls overlaid with stone masonry.
Resumo:
The DOF (DNA binding with One Finger) transcription factor (TF) family is characterized by a binding domain of 52 amino acid residues that is structured as a Cys2/Cys2 Zn2+ finger that recognizes the common core 5?-T/AAAAG-3? in the promoter regions of their target genes. DOF TFs have been associated with biological processes exclusive to higher plants and their close ancestors (algae, mosses and ferns).
Resumo:
The paper presents the results of a study on cultural trends in the abandonment of sports and physical activity among the Spanish youth. The study, that is being conducted due to a grant awarded by the Superior Sports Council (CSD) (Ref. 007/UPB10/12), examines how the adoption of this new lifestyle (sedentary) that is gradually taking root among the Spanish youth can influence one way or another the self-perceived health and well-being among this population.
Resumo:
Se describe la expresión por RTqPCR de los genes que codifican los factores transcripcionales bZIP44 y bZIP9. Asimismo se establece la interacción entre ambas proteínas en el sistema de 2 híbridos de levadura y in planta por complementación bimolecular fluorescente.