A home environment test battery for status assessment in patients with motor fluctuations

Background and aims Evaluating status in patients with motor fluctuations is complex and occasional observations/measurements do not give an adequate picture as to the time spent in different states. We developed a test battery to assess advanced Parkinson patients' status consisting of diary assessments and motor tests. This battery was constructed and implemented on a handheld computer with built-in mobile communication. In fluctuating patients, it should typically be used several times daily in the home environment, over periods of about one week. The aim of this battery is to provide status information in order to evaluate treatment effects in clinical practice and research, follow up treatments and disease progression and predict outcome to optimize treatment strategy. Methods Selection of diary questions was based on a previous study with Duodopa® (DIREQT). Tapping tests (with and without visual cueing) and a spiral drawing test were added. Rapid prototyping was used in development of the user interface. An evaluation with two pilot patients was performed before and after receiving new treatments for advanced disease (one received Duodopa® and one received DBS). Speed and proportion missed taps were calculated for the tapping tests and entropy of the radial drawing velocity was calculated for the spiral tests. Test variables were evaluated using non-parametric statistics. Results Post-treatment improvement was detected in both patients in many of the test variables. Conclusions Although validation work remains, preliminary results are promising and the test battery is currently being evaluated in a long-term health economics study with Duodopa® (DAPHNE).

Hälsofrämjande friskvårdsarbete : En fallstudie om friskvårdsarbete inom kommunal vård- och omsorgsförvaltning

Under senare år har frågan om ett hållbart arbetsliv blivit allt viktigare. Det innebär att goda arbetsförhållanden kommer att bidra till att människor orkar arbeta fram till pensionen. Friskvård har gått från att enbart vara en förmån till att bli en investering för att främja hälsa. Anställdas hälsa och arbetsmiljö är en del av personalfunktionens övergripande arbete för att behålla personal. Fysiskt krävande yrken som omsorgsarbete är ett stort arbetsmiljöproblem som kräver att organisationer försöker förhindra att arbetsrelaterad sjukdom inträffar. Syftet med detta examensarbete är att undersöka vilka förutsättningarna, ur ett medarbetarperspektiv, organisationer bör ta i beaktande för att skapa ett framgångsrikt arbete med hälsofrämjande friskvårdsaktiviteter inom kommunal vård- och omsorgsförvaltning. Arbetet är begränsat till personal inom Ludvika kommun. Friskvård kan förebygga sjukdom, men det kan också öka individens välbefinnande och kan därmed utgöra en framgångsrik strategi för att skapa hälsosammare arbetsplatser. En kombination av metoder användes för datainsamling, i form av en kvantitativ enkätundersökning och en kvalitativ fokusgruppintervju. Resultaten visade bland annat att majoriteten av de anställda är positiva till friskvård på arbetstid och att det är ett fördelaktigt sätt att öka deltagandet, även för dem som är mindre fysiskt aktiva. Tidsbrist och socialt stöd är skäl till varför fysisk aktivitet är lägre eller uteblir. Förutom att de anställda som har ett individuellt ansvar är det chefer, i samråd med organisationen, som har det övergripande ansvaret för att skapa goda förutsättningar för att främja hälsan.

Kostnader och risker med internationell verksamhet i Mexiko

Detta examensarbetes syfte är att identifiera vilka faktorer som påverkar kostnader och risker som kan finnas vid internationellt företagande i Mexiko utifrån ett perspektiv där företagande samt företagsomgivningar vanligtvis är stöttande och välfungerande. En litteraturstudie utfördes på Internationella verksamheter (International Business), och skapade intervjuunderlaget som användes för att intervjua företagare i Mexiko med erfarenheter av både internationell verksamhet samt USA/EU, och enbart erfarenheter från företagande inom landet. Resultat visar att det finns sex stycken samlingsområden som påverkar kostnader och risker; Politiska faktorer som innebär att drastiska förändringar orsakas i ett lands affärsomgivning, och som negativt påverkar ett företags vinster eller andra mål; Ekonomiska faktorer som innebär att det kostar mer att ha verksamhet på grund av brister inom infrastruktur och stödjande verksamheter; Den ekonomiska utvecklingen; Det finns utbredd korruption hos Mexikanska myndigheter på både lokal- och statsnivå; Ledningsprocesser och metoder kan behöva anpassas enligt kulturellt bestämda arbetsrelaterade värderingar; och Internationella verksamheter bör anställa lokala individer till hjälp att utföra affärer inom en specifik kultur.

Using adaptive automata in a multi-paradigm programming environment

In this paper the architecture of an experimental multiparadigmatic programming environment is sketched, showing how its parts combine together with application modules in order to perform the integration of program modules written in different programming languages and paradigms. Adaptive automata are special self-modifying formal state machines used as a design and implementation tool in the representation of complex systems. Adaptive automata have been proven to have the same formal power as Turing Machines. Therefore, at least in theory, arbitrarily complex systems may be modeled with adaptive automata. The present work briefly introduces such formal tool and presents case studies showing how to use them in two very different situations: the first one, in the name management module of a multi-paradigmatic and multi-language programming environment, and the second one, in an application program implementing an adaptive automaton that accepts a context-sensitive language.

Coaching for mindfulness and wisdom in complex environment

The primary objective for this paper is to build a compendium for a systemic intervention program for managers working in high-reliability organizations on an offshore rig. The second objective is then to work as a coach for these managers.

Shape changes of longan fruits during growth in a tropical environment

In this work we propose a new indicator to classify the best period for longan fruit harvest, based on measurements of its longitudinal and transversal axis during growth. Shape analysis based on area per volume ratio (AN) and sphericity show that those indicators stabilize after during longan growth period, independently of variety, in a specific environment. As sphericity increases 6% during fruits growth, AN ratio decreases dramatically (75%) closing to maturity, at 120 days after anthesis. The first derivative of A/V ratio indicates three distinct phases that are related to the growth phases of fruits. We believe that those shape indicators could be used to probe the right point of longan fruits maturity in different environments in a quantitative way.

Effects of sex and age on genotype x environment interaction for beef cattle body weight studied using reaction norm models

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

The work and health process in the sugarcane agroindustry in Franca, Brazil

This study aimed to discuss the interrelation between social determinants and the health conditions of workers in the sugarcane agroindustry in the region of Franca, in the countryside of São Paulo State, Brazil, from 2005 to 2006, considering the present socio-economic, historical, political and cultural conditions.

Does ISO 14001 work in Brazil?

As a result of increasing global awareness about the importance of the environment, depletion of natural resources and legal pressures for companies to manage their processes in a sustainable manner, ISO 14001 systems have been gaining increasingly more importance in the organizational scenario. These elements are even more critical in emerging nations due to less awareness and fewer demands by governments and the population in relation to environmental issues. Therefore, the main objective of this study is to verify the benefits and difficulties of Environmental Management Systems based on ISO 14001 at industries in the state of São Paulo - Brazil (an emerging country) by conducting a survey to subsidize the proposal for actions in the public, academic and private sectors to promote the use of this standard of reference and strengthen its results in Brazil. A questionnaire was sent to 194 companies from the National Institute of Metrology, Standardization and Industrial Quality database. 69 answered, representing a return rate of 35.36%. The main benefits identified are related to the development of preventive environmental actions, reduction in the consumption of power, water, gas and fuel oil, and a positive influence on other internal management processes. The main difficulties are related to cost increases from ISO 14001 management systems and the constant changes in environmental legislation in Brazil. Some actions are proposed at the end of the analyses to intensify the use and improve the results of this standard, such as changes in government legislation and its collective development and implementation in industries. (C) 2010 Elsevier Ltd. All rights reserved.

Participatory design in the project of virtual learning environment of histology

This present article describes a research on the development, under the approach of participatory design, a virtual teaching-learning of Histology in which students and teachers participated actively in all stages of development of the educational environment. We postulates that the development of virtual learning environment of Histology, through the Participatory Design approach, contributes to greater acceptance and use by students and that the adoption of virtual environment for teaching and learning by teachers is a determining factor of use by students

Interactions between environment, wild animals and human leptospirosis

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Genotype by environment interaction for 450-day weight of Nelore cattle analyzed by reaction norm models

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Classification and characterization of places for mapping of environment using hierarchical neural network and omnivision

Mobile robots need autonomy to fulfill their tasks. Such autonomy is related whith their capacity to explorer and to recognize their navigation environments. In this context, the present work considers techniques for the classification and extraction of features from images, using artificial neural networks. This images are used in the mapping and localization system of LACE (Automation and Evolutive Computing Laboratory) mobile robot. In this direction, the robot uses a sensorial system composed by ultrasound sensors and a catadioptric vision system equipped with a camera and a conical mirror. The mapping system is composed of three modules; two of them will be presented in this paper: the classifier and the characterizer modules. Results of these modules simulations are presented in this paper.

Image analysis for assessing broiler breeder behavior response to thermal environment

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Some comments on the F ring-Prometheus-Pandora environment

The system formed by the F ring and two close satellites, Prometheus and Pandora, has been analysed since the time that Voyager visited the planet Saturn. During the ring plane crossing in 1995 the satellites were found in different positions as predicted by the Voyager data. Besides the mutual effects of Prometheus and Pandora, they are also disturbed by a massive F ring. Showalter et al. [Icarus 100 (1992) 394] proposed that, the core of the ring has a mass which corresponds to a moonlet varying in size from 15 to 70 kin in radius which can prevent the ring from spreading due to dissipative forces, such as Poynting-Robertson drag and collisions. We have divided this work into two parts. Firstly we analysed the secular interactions between Prometheus-Pandora and a massive F ring using the secular theory. Our results show the variation in eccentricity and inclination of the satellites and the F ring taking into account a massive ring corresponding to a moonlet of different sizes. There is also a population of dust particles in the ring in the company of moonlets at different sizes [Icarus 109 (1997) 304]. We also analysed the behaviour of these particles under the effects of the Poynting-Robertson drag and radiation pressure. Our results show that the time scale proposed for a dust particle to leave the ring is much shorter than predicted before even in the presence of a coorbital moonlet. This result does not agree with the confinement model proposed by Dermott et al. [Nature 284 (1980) 309]. In 2004, Cassini mission will perform repeated observations of the whole system, including observations of the satellites and the F ring environment. These data will help us to better understand this system. (C) 2003 COSPAR. Published by Elsevier Ltd. All rights reserved.