Shooting for the Moon or Flying Too Near the Sun? Crossing the Value Rubicon in Precision Cancer Care

In his last two State of the Union addresses, President Barack Obama has focused on the need to deliver innovative solutions to improve human health, through the Precision Medicine Initiative in 2015 and the recently announced Cancer Moonshot in 2016. Precision cancer care has delivered clear patient benefit, but even for high-impact medicines such as imatinib mesylate (Glivec) in chronic myeloid leukaemia, the excitement at the success of this practice-changing clinical intervention has been somewhat tempered by the escalating price of this 'poster child' for precision cancer medicine (PCM). Recent studies on the costs of cancer drugs have revealed significant price differentials, which are a major causative factor behind disparities in the access to new generations of immunological and molecularly targeted agents. In this perspective, we will discuss the benefits of PCM to modern cancer control, but also emphasise how increasing costs are rendering the current approaches to integrating the paradigm of PCM unsustainable. Despite the ever increasing pressure on cancer and health care budgets, innovation will and must continue. Value-based frameworks offer one of the most rational approaches for policymakers committed to improving cancer outcomes through a public health approach.

Pose estimation of a humanoid robot using images from a mobile external camera

NOGUEIRA, Marcelo B. ; MEDEIROS, Adelardo A. D. ; ALSINA, Pablo J. Pose Estimation of a Humanoid Robot Using Images from an Mobile Extern Camera. In: IFAC WORKSHOP ON MULTIVEHICLE SYSTEMS, 2006, Salvador, BA. Anais... Salvador: MVS 2006, 2006.

Multimodal attention system for an interactive robot

[EN]Social robots are receiving much interest in the robotics community. The most important goal for such robots lies in their interaction capabilities. An attention system is crucial, both as a filter to center the robot’s perceptual resources and as a mean of letting the observer know that the robot has intentionality. In this paper a simple but flexible and functional attentional model is described. The model, which has been implemented in an interactive robot currently under development, fuses both visual and auditive information extracted from the robot’s environment, and can incorporate knowledge-based influences on attention.

CASIMIRO: a robot head for human-computer interaction

The physical appearance and behavior of a robot is an important asset in terms of Human-Computer Interaction. Multimodality is also fundamental, as we humans usually expect to interact in a natural way with voice, gestures, etc. People approach complex interaction devices with stances similar to those used in their interaction with other people. In this paper we describe a robot head, currently under development, that aims to be a multimodal (vision, voice, gestures,...) perceptual user interface.

Integrating an entertainment robot

[EN]In this paper we will present Eldi, a mobile robot that has been in opertation at the Elder Museum of Science and Technology at Las Palmas de Gran Canaria since december 1999. This is an ongoing project that was organized in three different stages of which only the first one has been accomplished. The initial phase, termed "The Player", the second stage, actually under develpment, has been called "The Cicerone" and in the final phase, termed "The Vagabond", in which Eldi will be allowed to move erratically across the Museum. This paper will focus on the accomplished first stage to succinctly describe the physical robot and the environment and demos developed. Finally we will summarize some important lessons learnt.

Eldi: an agent based museum robot

[EN]In this paper we will present Eldi, a mobile robot that has been in daily operation at the Elder Museum of Science and Technology at Las Palmas de Gran Canaria since December 1999. This is an ongoing project that was organized in three di erent stages, describing here the one that has been accomplished. The initial phase, termed \The Player", the second stage, actually under development, has been called "The Cicerone" and in a nal phase, termed \The Vagabond", Eldi will be allowed to move erratically across the Museum. This paper will focus on the accomplished rst stage to succinctly describe the physical robot and the environment and demos developed. Finally we will summarize some important lessons learnt.

Experiences with a museum robot

In this paper we will present Eldi, a mobile robot that has been in daily operation at the Elder Museum of S ien e and Te hnology at Las Palmas de Gran Canaria sin e last De ember. This is an ongoing pro je t that was organized in three di erent stages of whi h only the rst one has been a omplished. The initial phase, termed \The Player", the se ond stage, a tually under development, has been alled "The Ci erone" and in a nal phase, termed \The Vagabond", Eldi will be allowed to move errati ally a ross the Museum...

Localization of a mobile robot based on odometry and natural landmarks using extended kalman filter

SANTANA, André M.; SOUZA, Anderson A. S.; BRITTO, Ricardo S.; ALSINA, Pablo J.; MEDEIROS, Adelardo A. D. Localization of a mobile robot based on odometry and natural landmarks using extended Kalman Filter. In: INTERNATIONAL CONFERENCE ON INFORMATICS IN CONTROL, AUTOMATION AND ROBOTICS, 5., 2008, Funchal, Portugal. Proceedings... Funchal, Portugal: ICINCO, 2008.

Fast and accurate hand pose detection for human-robot interaction

[EN]Enabling natural human-robot interaction using computer vision based applications requires fast and accurate hand detection. However, previous works in this field assume different constraints, like a limitation in the number of detected gestures, because hands are highly complex objects difficult to locate. This paper presents an approach which integrates temporal coherence cues and hand detection based on wrists using a cascade classifier. With this approach, we introduce three main contributions: (1) a transparent initialization mechanism without user participation for segmenting hands independently of their gesture, (2) a larger number of detected gestures as well as a faster training phase than previous cascade classifier based methods and (3) near real-time performance for hand pose detection in video streams.

Disciplinary differences: a flying visit W1: taking an interdisciplinary approach

Overview of disciplinary differences taking a web science perspective as a starting point.

Diseño, construcción y control de un robot balancín.

Se diseñó, construyó, simuló e implementó un dispositivo robot balancín para la aplicación y estudio de técnicas avanzadas de control. Para esto se realizó el diseño mecánico del dispositivo, de acuerdo a una elección entre dos modelos distintos y cuatro tipos diferentes de transmisión. Luego se instrumentó el dispositivo con encoders de posición , acelerómetro y giróscopo para obtener el estado del dispositivo y controlarlo. Se realizó una placa electrónica para la lectura y procesamiento de señales de sensores con un micro controlador, un regulador de tensión, y un driver para los motores, capaz de obtener las señales de los encoders y el módulo acelerómetro-giróscopo y enviarlas por comunicación hacia una mini-computadora, la cual ejecuta el control, y se comunica nuevamente a la placa diseñada para comandar los motores. Se desarrolló un modelo teórico simplificado en dos dimensiones para facilitar la posterior identificación de planta. Se realizaron experimentos para lograr una identificación de planta. A partir de lo obtenido, se diseñó y simuló el control necesario para mantener la estabilidad. Se implementó posteriormente el control diseñado. Se reajustaron los parámetros correspondientes de acuerdo a la práctica experimental para mejorar la respuesta dinámica del sistema.

Sistema di guida robot per operazioni di pick and place

Uno dei fattori che ha favorito la diffusione della robotica è legato alla nascita, allo sviluppo e al perfezionamento dei sistemi di guida robot. Per guida robot si intende un sistema di visione artificiale capace di guidare un robot durante lo svolgimento di un determinato compito. All'interno di questo elaborato di tesi, verrà illustrato in dettaglio un sistema di guida robot realizzato per una operazione di pick and place 2D multistrato. Sebbene la procedura proposta sia stata sviluppata per risolvere un problema specifico, la sua validità è del tutto generale e può essere estesa anche ad altre applicazioni appartenenti alla stessa categoria.

Modélisation de la sécurité des tâches coopératives humain-robot

L’interaction physique humain-robot est un domaine d’étude qui s’est vu porter beaucoup d’intérêt ces dernières années. Une optique de coopération entre les deux entités entrevoit le potentiel d’associer les forces de l’humain (comme son intelligence et son adaptabilité) à celle du robot (comme sa puissance et sa précision). Toutefois, la mise en service des applications développées reste une opération délicate tant les problèmes liés à la sécurité demeurent importants. Les robots constituent généralement de lourdes machines capables de déplacements très rapides qui peuvent blesser gravement un individu situé à proximité. Ce projet de recherche aborde le problème de sécurité en amont avec le développement d’une stratégie dite "pré-collision". Celle-ci se caractérise par la conception d’un système de planification de mouvements visant à optimiser la sécurité de l’individu lors de tâches d’interaction humain-robot dans un contexte industriel. Pour ce faire, un algorithme basé sur l’échantillonnage a été employé et adapté aux contraintes de l’application visée. Dans un premier temps, l’intégration d’une méthode exacte de détection de collision certifie que le chemin trouvé ne présente, a priori, aucun contact indésirable. Ensuite, l’évaluation de paramètres pertinents introduit notre notion de sécurité et définit un ensemble d’objectifs à optimiser. Ces critères prennent en compte la proximité par rapport aux obstacles, l’état de conscience des êtres humains inclus dans l’espace de travail ainsi que le potentiel de réaction du robot en cas d'évènement imprévu. Un système inédit de combinaison d’objectifs guide la recherche et mène à l’obtention du chemin jugé comme étant le plus sûr, pour une connaissance donnée de l’environnement. Le processus de contrôle se base sur une acquisition minimale de données environnementales (dispositif de surveillance visuelle) dans le but de nécessiter une installation matérielle qui se veut la plus simple possible. Le fonctionnement du système a été validé sur le robot industriel Baxter.