Report on the Iowa Department of Justice for the year ended June 30, 2014

Report on the Iowa Department of Justice for the year ended June 30, 2014

Recovery of a persistent Canine distemper virus expressing the enhanced green fluorescent protein from cloned cDNA.

Wild-type A75/17-Canine distemper virus (CDV) is a highly virulent strain, which induces a persistent infection in the central nervous system (CNS) with demyelinating disease. Wild-type A75/17-CDV, which is unable to replicate in cell lines to detectable levels, was adapted to grow in Vero cells and was designated A75/17-V. Sequence comparison between the two genomes revealed seven nucleotide differences located in the phosphoprotein (P), the matrix (M) and the large (L) genes. The P gene is polycistronic and encodes two auxiliary proteins, V and C, besides the P protein. The mutations resulted in amino acid changes in the P and V, but not in the C protein, as well as in the M and L proteins. Here, a rescue system was developed for the A75/17-V strain, which was shown to be attenuated in vivo, but retains a persistent infection phenotype in Vero cells. In order to track the recombinant virus, an additional transcription unit coding for the enhanced green fluorescent protein (eGFP) was inserted at the 3' proximal position in the A75/17-V cDNA clone. Reverse genetics technology will allow us to characterize the genetic determinants of A75/17-V CDV persistent infection in cell culture.

Predictors of functional recovery in patients admitted to geriatric postacute rehabilitation.

OBJECTIVE: To examine characteristics associated with functional recovery in older patients undergoing postacute rehabilitation. DESIGN: Observational study. SETTING: Postacute rehabilitation facility. PARTICIPANTS: Patients (N=2754) aged ≥65 years admitted over a 4-year period. INTERVENTIONS: Not applicable. MAIN OUTCOME MEASURE: Functional status was assessed at admission and again at discharge. Functional recovery was defined as achieving at least 30% improvement on the Barthel Index score from admission compared with the maximum possible room for improvement. RESULTS: Patients who achieved functional recovery (70.3%) were younger and were more likely to be women, live alone, and be without any formal home care before admission, and they had fewer chronic diseases (all P<.01). They also had better cognitive status and a higher Barthel Index score both at admission (mean ± SD, 63.3±18.0 vs 59.6±24.7) and at discharge (mean ± SD, 86.8±10.4 vs 62.2±22.9) (all P<.001). In multivariate analysis, patients <75 years of age (adjusted odds ratio [OR]=1.51; 95% confidence interval [CI], 1.16-1.98; P=.003), women (adjusted OR=1.24; 95% CI, 1.01-1.52; P=.045), patients living alone (adjusted OR=1.61; 95% CI, 1.31-1.98; P<.001), and patients without in-home help prior to admission (adjusted OR=1.39; 95% CI, 1.15-1.69; P=.001) remained at increased odds of functional recovery. In addition, compared with those with moderate-to-severe cognitive impairment (Mini-Mental State Examination score <18), patients with mild-to-moderate impairment (Mini-Mental State Examination score 19-23) and those cognitively intact also had increased odds of functional recovery (adjusted OR=1.56; 95% CI, 1.13-2.15; P=.007; adjusted OR=2.21; 95% CI, 1.67-2.93; P<.001, respectively). CONCLUSIONS: Apart from sociodemographic characteristics, cognition is the strongest factor that identifies older patients more likely to improve during postacute rehabilitation. Further study needs to determine how to best adapt rehabilitation processes to better meet the specific needs of this population and optimize their outcome.

Audit report on the Black Hawk County Criminal Justice Information System for the year ended June 30, 2015

Audit report on the Black Hawk County Criminal Justice Information System for the year ended June 30, 2015

Nouveaux règlemens pour l'administration de la justice, avec les tarifs des droits dûs aux officiers de justice pour leurs frais et salaires, et la taxe des dépens de tous les procès. 3e éd.. Edition 3,Tome 1

[Acte royal]

Nouveaux règlemens pour l'administration de la justice, avec les tarifs des droits dûs aux officiers de justice pour leurs frais et salaires, et la taxe des dépens de tous les procès. 3e éd.. Edition 3,Tome 2

[Acte royal]

Ministère de la guerre. Direction (du contentieux, de la justice militaire et de) la gendarmerie (sous-direction de la gendarmerie, bureau technique). Décret sur l'organisation de la gendarmerie. Document abrogé : décret du 1er novembre 1928...

[Décret. 1928-11-01]

HLA-Bw4 homozygosity is associated with an impaired CD4 T cell recovery after initiation of antiretroviral therapy.

We assessed the influence of human leukocyte antigen (HLA) alleles HLA-Bw4 and HLA-Bw6 on CD4 T cell recovery after starting successful combination antiretroviral therapy in 265 individuals. The median gains in the CD4 T cell count after 4 years were 258 cells/microL for HLA-Bw4 homozygotes, 321 cells/microL for HLA-Bw4/Bw6 heterozygotes, and 363 cells/microL for HLA-Bw6 homozygotes (P = .01, compared with HLA-Bw4 homozygotes). HLA-Bw4 homozygosity appears to predict an impaired CD4 T cell recovery after initiation of combination antiretroviral therapy.

Auguste Ott on Commercial Crises and Distributive Justice: An Early Input-Output Scheme

In 1851 the French Social economist Auguste Ott discussed the problem of gluts and commercial crises, together with the issue of distributive justice between workers in co-operative societies. He did so by means of a 'simple reproduction scheme' sharing some features with modern intersectoral transactions tables, in particular in terms of their graphical representation. This paper presents Ott's theory of crises (which was based on the disappointment of expectations) and the context of his model, and discusses its peculiarities, supplying a new piece for the reconstruction of the prehistory of input-output analysis.

Justice et criminalité (Vaud, XVe-XXIe siècles)

A la veille de l'introduction de la réforme pénale et civile fédérale dans le canton de Vaud en 2011, la Revue historique vaudoise s'est intéressée à l'histoire de la justice et de la criminalité. Le présent numéro réunit des contributions d'historiens, historiens du droit et historiens de l'art, jeunes ou confirmés, qui livrent ici les résultats de leurs recherches en cours ou récentes, ainsi que des témoignages de magistrats sur l'exercice de la justice et sur les conséquences des changements à venir. Pour cette thématique qui est un champ dynamique de la recherche historiques en Suisse et en Europe depuis la fin des années 1970, deux axes principaux ont été privilégies pour interroger l'exercice de la justice et les interactions entre l'Etat et les justiciables. Le premier traite de la figure du criminel et de la représentation du crime par un examen des pratiques et des discours judiciaires. Le second se concentre sur les acteurs de la justice et sur leurs modes d'actions et leurs motivations. En privilégiant un traitement sur la longue durée, du Moyen Âge à nos jours, ainsi que des études de cas, ce dossier thématique propose des éclairages successifs sur la justice et la criminalité en terres vaudoises. Ils mettent en évidence des transitions, des ruptures et des innovations révélatrices des institutions, de leur fonctionnement et du rôle social de leurs agents