Memoirs of an aristocrat, and reminiscences of the Emperor Napoleon.

Mode of access: Internet.

The life of the emperor Napoleon. With an appendix, containing an examination of Sir W. Scott's "Life of Napoleon Bonaparte;" and a notice of the principal errors of other writers, respecting his character and conduct.

No more published under this title. "Subsequently enlarged and published in Paris and London as the Life of Napoleon Bonaparte down to the peace of Tolentino."--Brown, Cyclopaedia of American biographies.

Journal of the private life and conversations of the emperor Napoleon at Saint Helena.

[In 8 separately paged parts, each vol. containing 2 pts.]

The history of Etruria... [microform]

pt. 1. Tarchun and his times. From the foundation of Tarquinia to the foundation of Rome.--pt. II. From the foundation of Rome to the general peace of anno Tarquiniae, 839 (B.C. 348)--pt. III. With an account of the manners and customs, arts and literature of the Etruscans, tr. from the German of Karl Otfried Müller.

The substance of some letters written from Paris during the last reign of the Emperor Napoleon : and addressed principally to the Right Hon. Lord Byron /

Mode of access: Internet.

The last days of the Emperor Napoleon, /

Mode of access: Internet.

The religion of ancient Rome;

"Works bearing on the early religion of Rome": p. [114]

Campaigns of the armies of France, in Prussia, Saxony, and Poland, under the command of His Majesty the emperor and king, in MDCCCVI and VII : a work destined to record the great events of that memorable era, and the brilliant achievements of the generals, officers, and soldiers : accompanied with biographical notices upon those who fell during that memorable campaign : also, with historical and military details of the sieges and battles which have signalized the different countries, through which the French have just marched their armies /

Includes index.

Recollections of the Emperor Napoleon : during the first three years of his captivity on the island of St. Helena, including the time of his residence at her father's house, "The Briars" /

Mode of access: Internet.

Syn Velikoĭ Ekateriny; Imperator Pavel I, ego zhiznʹ, t︠s︡arstvovanīe i smertʹ, 1754-1801. Po novym, bolʹshei︠u︡ chastʹi︠u︡ neizdannym dokumentam. S 68 illi︠u︡strat︠s︡īi︠a︡mi na otdi︠e︡lʹnykh listakh i 61 risunkom.

Mode of access: Internet.

Topographical study in Rome in 1581. A series of views with a fragmentary text

Introduction includes a catalogue of archaeological sketch-books which include views of Rome (p. 7-16)

The home and court life of the Emperor Napoleon and his family, with pictures of the most distinguished persons of the time,

Added title page: The autobiography and recollections of Laura, duchess of Abrantès (widow of General Junot) : with reminiscences of her life in Corsica, Paris, and in Spain and Portugal.

A METÁFORA DO CORPO NA I CARTA DE CLEMENTE DE ROMA AOS CORÍNTIOS (37.5-38.1): Uma análise dialógica

A I Carta de Clemente de Roma aos Coríntios faz parte de uma coleção de escritos cristãos antigos intitulados Pais Apostólicos. Esse texto é uma autêntica correspondência enviada da comunidade cristã de Roma para a comunidade cristã de Corinto, escrita pelo seu secretário Clemente. Esta pesquisa, em contraposição às desenvolvidas pela disciplina teológica chamada patrologia , analisa a carta a partir das teorias de Mikhail M. Bakhtin e seu círculo e da micro-história assumidamente relacionada com as teorias do mesmo autor delimitando o trecho 37.5-38.1, onde se encontra a metáfora do corpo.

Influence of ABCB1 polymorphisms and haplotypes on tacrolimus nephrotoxicity and dosage requirements in children with liver transplant

WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT • Currently tacrolimus is the mainstay of immunosuppression for most children undergoing liver transplantation (LT). • The clinical use of this agent, however, is complicated by its various adverse effects (mainly nephrotoxicity), its narrow therapeutic-index and considerable pharmacokinetic variability. • The low and variable oral bioavailability of tacrolimus is thought to result from the action of the multidrug efflux-pump P-glycoprotein, encoded by the ABCB1 gene. WHAT THIS STUDY ADDS • A significant association between ABCB1 genetic polymorphisms and tacrolimus-associated nephrotoxicity in paediatric patients following LT is reported for the first time. Genotyping such polymorphisms may have the potential to individualize better initial tacrolimus therapy and enhance drug safety. • The long-term effect of ABCB1 polymorphisms on tacrolimus trough concentrations were investigated up to 5 years post-transplantation. A significant effect of intestinal P-glycoprotein genotypes on tacrolimus pharmacokinetics was found at 3 and 4 years post-transplantation suggesting that the effect is maintained long term. AIMS - The aim of this study was to investigate the influence of genetic polymorphisms in ABCB1 on the incidence of nephrotoxicity and tacrolimus dosage-requirements in paediatric patients following liver transplantation. METHODS - Fifty-one paediatric liver transplant recipients receiving tacrolimus were genotyped for ABCB1 C1236>T, G2677>T and C3435>T polymorphisms. Dose-adjusted tacrolimus trough concentrations and estimated glomerular filtration rates (EGFR) indicative of renal toxicity were determined and correlated with the corresponding genotypes. RESULTS - The present study revealed a higher incidence of the ABCB1 variant-alleles examined among patients with renal dysfunction (≥30% reduction in EGFR) at 6 months post-transplantation (1236T allele: 63.3% vs 37.5% in controls, P= 0.019; 2677T allele: 63.3% vs. 35.9%, p = 0.012; 3435T allele: 60% vs. 39.1%, P= 0.057). Carriers of the G2677->T variant allele also had a significant reduction (%) in EGFR at 12 months post-transplant (mean difference = 22.6%; P= 0.031). Haplotype analysis showed a significant association between T-T-T haplotypes and an increased incidence of nephrotoxicity at 6 months post-transplantation (haplotype-frequency = 52.9% in nephrotoxic patients vs 29.4% in controls; P= 0.029). Furthermore, G2677->T and C3435->T polymorphisms and T-T-T haplotypes were significantly correlated with higher tacrolimus dose-adjusted pre-dose concentrations at various time points examined long after drug initiation. CONCLUSIONS - These findings suggest that ABCB1 polymorphisms in the native intestine significantly influence tacrolimus dosage-requirement in the stable phase after transplantation. In addition, ABCB1 polymorphisms in paediatric liver transplant recipients may predispose them to nephrotoxicity over the first year post-transplantation. Genotyping future transplant recipients for ABCB1 polymorphisms, therefore, could have the potential to individualize better tacrolimus immunosuppressive therapy and enhance drug safety.

Factors Affecting De Novo Urinary Retention after Holmium Laser Enucleation of the Prostate

Objective Patients can experience urinary retention (UR) after Holmium laser enucleation of the prostate (HoLEP) that requires bladder distension during the procedure. The aim of this retrospective study is to identify factors affecting the UR after HoLEP. Materials and Methods 336 patients, which underwent HoLEP for a symptomatic benign prostatic hyperplasia between July 2008 and March 2012, were included in this study. Urethral catheters were routinely removed one or two days after surgery. UR was defined as the need for an indwelling catheter placement following a failure to void after catheter removal. Demographic and clinical parameters were compared between the UR (n = 37) and the non-urinary retention (non-UR; n = 299) groups. Results The mean age of patients was 68.3 (±6.5) years and the mean operative time was 75.3 (±37.4) min. Thirty seven patients (11.0%) experienced a postoperative UR. UR patients voided catheter free an average of 1.9 (±1.7) days after UR. With regard to the causes of UR, 24 (7.1%) and 13 (3.9%) patients experienced a blood clot-related UR and a non-clot related UR respectively. Using multivariate analysis (p<0.05), we found significant differences between the UR and the non-UR groups with regard to a morcellation efficiency (OR 0.701, 95% CI 0.498–0.988) and a bleeding-related complication, such as, a reoperation for bleeding (OR 0.039, 95% CI 0.004–0.383) or a transfusion (OR 0.144, 95% CI 0.027–0.877). Age, history of diabetes, prostate volume, pre-operative post-void residual, bladder contractility index, learning curve, and operative time were not significantly associated with the UR (p>0.05). Conclusions De novo UR after HoLEP was found to be self-limited and it was not related to learning curve, patient age, diabetes, or operative time. Efficient morcellation and careful control of bleeding, which reduces clot formation, decrease the risk of UR after HoLEP.