Desenvolvimento do cultivo 3D a partir de células primarias de neoplasias mamárias caninas: estudo da apoptose sobre efeito ou não da carboplatina

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Aspectos culturais como fios condutores de interações em Tandem na aprendizagem de português língua estrangeira: interculturalidade, estereótipos e identidade(s)

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Análise das células tronco tumorais em neoplasias mamárias de cães

Mammary tumors are the most frequent cancers in dogs, representing about 50% of tumors, and have a higher incidence in females of middle aged and elderly. These tumors have been used as a model for breast cancer in women due to several common characteristics such as histological and immunohistochemical similarities. In the last decade, studies based on molecular profiles of breast cancer, made possible the identification of some neoplastic cells with characteristics of stem cells - cancer stem cells (CSC). One of the putative molecules of CSCs is CD44. Recent studies have established a crucial link between the epithelial-mesenchymal transition (EMT) and the acquisition of molecular and functional properties of stem cells. For that reason we analyzed the expression of proteins CD44, Cytokeratins AE1/AE3 and Vimentin, in dogs mammary tumors, to investigate the potencial for CSC markers, and its relation with the EMT using immunohistochemistry in paraffin embedded tissues making use of techniques such as Tissue MicroArrays (TMA). Immunostaining of cytokeratin had no significant difference between benign and malignant tumors (p ≥ 0,05), being more intense in malignant tumors. However vimentina showed higher staining intensity in benign tumors, but with no significant difference (p ≤ 0,05). The expression of CD44 was higher in malignant tumors that have greater proliferative and metastatic potencial, however its relation with EMT was not detected in the analyzed tumors. The techniques applied for the TMAs were efficient and can be used in routine and later researches.

Carcinoma escamoso oral: análise retrospectiva de 185 casos

The squamous cell carcinoma is the most common malignancy in the oral cavity, representing over 90% of cancers in this region. This study aimed to conduct an epidemiological study of oral squamous carcinoma cases diagnosed by the Department of Pathology, Department of Pathology and Clinical Propaedeutics in the Dentistry Faculty of Araçatuba - UNESP, in the period between 1995 and 2005. 185 cases were studied, it was observed that the oral floor and tongue were the sites most affected, with predominance in males, white race and aged between 41 and 60 years, noting that the majority of patients were smokers. Knowledge of these data is important for the dental surgeon to act preventively, contributing to early diagnosis of cancer.

O ensino de língua estrangeira nas escolas públicas estaduais paulistas e as novas tecnologias

Pós-graduação em Televisão Digital: Informação e Conhecimento - FAAC

Avaliação do ler e do escrever de surdos pela língua brasileira de sinais

The use of Brazilian Sign Language (BSL) in the education of deaf people is guaranteed by Brazilian laws, but its adoption in educational policies requires an adjustment in terms of stimulus and response modalities. This study aimed at characterizing reading and writing performances of four deaf students who are BSL users and are in early literacy phases. The assessment was performed through selection tasks – signaling and writing – using an evaluation and teaching procedure that is usually adopted with hearing children. The results replicated data that has been documented in hearing children: performance was satisfactory in copying and identity matching tasks among pictures and graphic stimulus; performance was lower in reading and dictation tasks. Data show that investment targets regarding reading and writing teaching conditions programming require adjustments that are more related to the communication modality than to the teaching procedures.

O desafio da interação no ensino de língua estrangeira em cursos on-line e presenciais nas escolas públicas paulistas

La popularización de los medios digitales y los recursos de comunicación difunde las narrativas no lineales y agrava la crisis de la enseñanza en el aula, con la expansión de diferentes modelos presenciales virtuales de la educación (PVE). Es evidente la demasificación de los nuevos medios, en un contexto que agudiza la percepción individual y social de los individuos, que son atraídos por el enorme flujo global de mensajes informativos (BRIGGS; BURKE, 2006). La transición de los métodos de enseñanza en el aula para modelar la educación virtual e interactiva ganó un nuevo formato en la educación pública en São Paulo en 2012, con el lanzamiento de cursos electivos de enseñanza de Inglés y Español para estudiantes de la secundaria, con la mediación de el PC y con el contenido producido por la Escuela Virtual de Programas Educativos del Estado de São Paulo - Evesp. Aún continua presencia en los salones de las grandes clases del sistema escolar, la falta de materiales de enseñanza y aprendizaje adecuados en las clases impartidas por los profesores cuyos repertorios están alejados de la vida cotidiana de los estudiantes. En este contexto, se comprueban las actuaciones de aprendizaje cualitativos más bien negativos de las cuatro habilidades comunicativas: escuchar, hablar, leer y escribir (CAMERON, 2001). La investigación que llevamos a cabo es analizar las experiencias de enseñanza de Inglés y Español en la plataforma computarizada Evesp y de la clase de Inglés y Español de los Centros para el Curso de idiomas (CELS), para la escuela secundaria, y el piloto Early Bird, de enseñanza y el aprendizaje de Inglés de la escuela primaria, todos bajo la Junta de Educación de Bauru (SP).

As contribuições do dialogismo de bakhtin e do signo em umberto eco para o ensino de língua estrangeira

This article discusses the dialogism in Mikhail Bakhtin and the grounds of the linguistic sign in Umberto Eco, with the intention to use the themes and authors, to support the teaching-learning methodologies of foreign language (English and Spanish) at the public school of São Paulo state. The conceptual approach of the two authors allows us to infer that learning a foreign language is effected by the appropriation of utterances and cultural knowledge, pedagogical concept that confronts the traditional method used in the São Paulo school, which is based mainly on grammar teaching and lexicons. The paper derives the theoretical research used to support a dissertation, posing and evaluates preliminary, the integration of traditional theaters in foreign language in public schools, with digital environments (in online courses), and also the educational effects -the use of audiovisual material at the classroom and online learning.

Concepção de produção de texto na escola: os reflexos no ensino da língua materna na sala do 5º ano do Ensino Fundamental

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

O hipertexto na escola: a retextualização digital nas aulas de língua portuguesa

Pós-graduação em Letras - FCLAR

Repositórios de objetos de aprendizagem de língua portuguesa no ensino fundamental: alternativas para professores

Pós-graduação em Letras - FCLAR

Análise dos conteúdos de língua portuguesa do “Programa Ler e Escrever” em uma escola municipal de ensino fundamental

Pós-graduação em Educação - FFC

Língua portuguesa no ensino médio: repertórios de ensino no âmbito do programa São Paulo faz Escola

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

A língua portuguesa no 5º ano do ensino fundamental: repertórios de ensino no contexto da Prova Brasil/ SAEB

Pós-graduação em Psicologia do Desenvolvimento e Aprendizagem - FC

Uma análise do ensino de língua inglesa por meio do uso das Tecnologias Digitais da Informação e Comunicação

Pós-graduação em Educação - FFC