Huanglongbing (ex-greening): um alerta aos citricultores da Bahia.

A produção de citros no Brasil é uma das principais atividades do agronegócio nacional, apresentando significativa importância econômica e social devido aos números vultosos de produção. A Bahia destaca-se como o segundo produtor nacional de laranja. Para manter esse desempenho, cuidados devem ser empregados a fim de garantir a sanidade dos pomares do estado. Dentre as doenças que afetam os citros, o huanglongbing (HLB), comumente chamado de ?greening? é altamente devastador e amplamente distribuído no mundo. Essa doença tornou-se importante no cenário brasileiro desde 2004, quando ocorreram os primeiros registros no estado de São Paulo. O HLB é causado pela bactéria Candidatus Liberibacter, que no Brasil está associada às formas Ca. L. asiaticum e Ca. L. americans. A disseminação do HLB pode ocorrer por enxertia de material contaminado ou pelo inseto vetor da bactéria, o psilídeo Diaphorina citri Kuwayama (Hemyptera: Psyllidae). Além dos citros, o D. citri também utiliza como hospedeiro a espécie Murraya paniculata, popularmente conhecida como murta.

Diagnose das principais doenças do cupuaçuzeiro (Theobroma grandiflorum (Willd. ex Spreng.) Schum.) e seu controle.

Cupuaçu: vassoura-de-bruxa, morte progressiva, podridao vermelha, mancha de Phomopsis.

Produção de mudas de cupuaçu (Theobroma grandiflorum (Willd. ex Spreng. Schum.).

Informacoes tecnicas sobre producao de mudas de cupuacu: propagacao por sementes (selecao, preparo e conservacao), embalagem, preparo do substrato, semeadura, propagacao vegetativa por enxertia (borbulhia: obtencao das hastes, preparo do porta-enxerto e execucao da enxertia), viveiro (escolha do local, construcao, arrumacao e cuidados), transporte das mudas, legislacao e orcamento para producao de 10.000 mudas de cupuacu, em Manaus, Amazonas, Brasil.

A cultura do cupuaçu (Theobroma grandiflorum (Willd. ex Spreng.) Schum.).

Cupuaçu: classificacao botanica, origem e distribuicao, condicoes climaticas e fenologia, propagacao, implantacao da cultura, tratos culturais, doencas e pragas e seu controle, produtividade, colheita e beneficiamento, produtos derivados, comercializacao, coeficientes tecnicos, no Estado do Amazonas (Brasil).

Estudo preliminar da cadeia produtiva do cupuaçu (Theobroma grandiflorum (Willd. ex Spreng.) Schum) no Amazonas.

Caracterização geral da cadeia produtiva do cupuaçu. Setor produtivo. Agregação de valores - Agroindústria. Comercialização. Consumidor final. Análise diagnóstica. Análise prognóstica. Identificação de limitações estruturais e tecnológicas da cadeia produtiva do cupuaçu. Demandas identificadas.

Comparative proteomics of excretory-secretory proteins released by the liver fluke Fasciola hepatica in sheep host bile and during in vitro culture ex host

Russell M. Morphew, Hazel A. Wright, E. James LaCourse, Debra J. Woods and Peter M. Brophy (2007). Comparative proteomics of excretory-secretory proteins released by the liver fluke Fasciola hepatica in sheep host bile and during in vitro culture ex host. Molecular and Cellular Proteomics, 6 (6), 963-972. Sponsorship: BBSRC / EU RAE2008

Equal citizenship for a new society? An analysis of training and employment opportunities for republican ex-prisoners in Belfast

Previous research evidence appears to suggest that while they suffer from similiar socio-economic problems to the wider nationalist community, the problems for republican ex-prisoners seem to be on a greater scale. The primary objective of this research was to investigate the current obstacles facing republication ex-prisoners in training and employment and to make proposals for change.

Ex vivo culture of patient tissue and examination of gene delivery

Gene therapy has emerged as a realistic prospect for the treatment of cancer due to its potential for selective tumour cell targeting. The greatest challenge gene delivery vectors face is the ability to safely and efficiently deliver genes into target cells. The overall objectives of this thesis are to evaluate the efficacy of various gene delivery methods in a clinically relevant tumour model and to also investigate potential strategies for tumour selective delivery. We began with the development of a tumour slice model system using patient waste tissue. This model involves the use of fresh human tumour tissue, cut into thin slices and maintained ex vivo and is universally applicable to gene delivery methods, using a real-time luminescence detection method to assess gene delivery. The nature of the ex vivo culture system permitted examination of specific physiological variables, the influence of intratumoural factors and tissue specific effects on vector expression. Adenoviral vectors under the control of the human CXCR4 promoter demonstrated a 'tumour on' and 'normal off' expression profile when compared with the ubiquitously active CMV promoter when tested in patient tumour tissue. In addition, we developed an ex vivo system of changing oxygenation using the hypoxia inducer, cobalt, to mimic the transient hypoxic conditions found in solid tumours. We found that Adenoviral transgene expression was robust in the cycling hypoxic conditions relevant to solid tumours and re-oxygenation of chronically hypoxic tissue enhanced transgene expression. Finally, we demonstrated an AAV-based tumour targeting strategy using a tumour-selective promoter allowing for the efficient targeting of AAV vectors to cancer cells and the sparing of normal tissue in both murine metastatic liver tumours models and patient tissue. The thesis highlights the importance of indepth preclinical assessment of novel therapeutics and may serve as a platform for further testing of novel gene delivery approaches.

Empirical Evidence on Relationships between Ex Ante Innovation Pursuit and Post-M&A Performance in the Vietnamese M&A Industry, 2005-2012

This research aims to communicate new results of empirical investigations to learn about the relationship between determination of controlling an acquired firm’s capital, assets and brand versus its capability of innovation and ex post performance of the rising Vietnamese M&A industry in the 2005-2012 period. The analysis employs a categorical data sample, consisting of 212 M&A cases reported by various information sources, and performs a number of logistic regressions with significant results as follows. Firstly, the overall relationship between pre-M&A pursuit’s determination on acquiring resources and performance of the post-M&A performance is found significant. There exist profound effects of a ‘size matters’ strategy in M&A ex post performance. When there is an overwhelming ‘resources acquiring’ strategy, the innovation factor’s explanatory power becomes negligible. Secondly, for negative performance of post-M&A operations, the emphasis on both capital base and asset size, and the brand value at the time of the M&A pursuit is the major explanation in the post-M&A period. So does the absence of innovation as a goal in the pre-M&A period. These two insights together are useful in careful M&A planning. Lastly, expensive pre-M&A expenditures tend to adversely affect the post-M&A performance. As a general conclusion, this study shows that innovation can be an important factor to pursue in M&A transitions, together with the need to emphasize and find capable and willing human capital, rather than a capital base (equity or debt) and existing values of the acquired brands.

Silene acutifolia Link ex Rohrb.en El Bierzo (León)

En esta nota se da a conocer una nueva localidad de Silene acutifolia situada en la comarca leonesa de El Bierzo. Sin rebasar su ámbito Orensano-Sanabriense, esta localidad amplía considerablemente su área española.

Contribución al estudio anatómico de los géneros Elaeoselinum Koch ex DC., Margotia Boiss. y Distichoselinum García Martín & Silvestre (Umbelliferae), en la Península Ibérica

Se realiza el estudio anatómico de los tallos, hojas y frutos de los taxones ibéricos del género Elaeoselinum s.l. y se discute el valor de los caracteres anatómicos, en orden a considerar como géneros independientes Elaeoselinum Koch ex DC., Margotia Boiss. y Distichoselinum García Martín & Silvestre.