Discurso sobre que relaciones esisten entre la hidrologia y ciencias naturales y memoria de los baños de Caldelas de Tuy /

Este trabajo fué leído por el autor en el primer ejercicio de la oposición a baños de 1866.

Dictionariu[m] Aelij Antonij Nebrissen[sis] ...

Mode of access: Internet.

Memorias de las Reynas Catholicas de España : historia genealogica de la casa real de Castilla y de Leon, todos los infantes, trages de las reynas en estampas y nuevo aspecto de la historia de España.

Aguilar Piñal 4153 (Los dos vol. de la obra)

Encyclopédie du commerçant. Dictionnaire du commerce et des marchandises

Paged continuously; v. 1: 1 p. l., 996 p.; v. 2: 2 p. l., [997]-2252 p.

An analysis of selected issues in the minor construction program : a consultative report for the Director, Facility Engineering, Planning, and Construction Office, Department of Medicine and Surgery /

"September 1985."

A rapid HPLC-mass spectrometry cyclosporin method suitable for current monitoring practices

Objectives: Cyclosporin is an immunosuppressant drug with a narrow therapeutic window. Trough and 2-h post-dose blood samples are currently used for therapeutic drug monitoring in solid organ transplant recipients. The aim of the current study was to develop a rapid HPLC-tandem mass spectrometry (HPLC-MS) method for the measurement of cyclosporin in whole blood that was not only suitable for the clinical setting but also considered a reference method. Methods: Blood samples (50 mu L) were prepared by protein precipitation followed by C-18 solid-phase extraction while using d(12) cyclosporin as the internal standard. Mass spectrometric detection was by selected reaction monitoring with an electrospray interface in positive ionization mode. Results: The assay was linear from 10 to 2000 mu g/L (r(2) > 0.996, n = 9). Inter-day,analytical recovery and imprecision using whole blood quality control samples at 10, 30, 400, 1500, and 2000 mu g/L were 94.9-103.5% and