Healing of normal and osteopenic bone with titanium implant and low-level laser therapy (GaAlAs): a histomorphometric study in rats

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Atores, cenários e planos: o planejamento estratégico situacional e a educação

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Search for pair production of third-generation scalar leptoquarks and top squarks in proton-proton collisions at v root s=8 TeV

A search for pair production of third-generation scalar leptoquarks and supersymmetric top quark partners, top squarks, in final states involving tau leptons and bottom quarks is presented. The search uses events from a data sample of proton-proton collisions corresponding to an integrated luminosity of 19.7 fb(-1), collected with the CMS detector at the LHC with root s = 8 TeV. The number of observed events is found to be in agreement with the expected standard model background. Third-generation scalar leptoquarks with masses below 740 GeV are excluded at 95% confidence level, assuming a 100% branching fraction for the leptoquark decay to a tau lepton and a bottom quark. In addition, this mass limit applies directly to top squarks decaying via an R-parity violating coupling. lambda(') (333). The search also considers a similar signature from top squarks undergoing a chargino-mediated decay involving the Rparity violating coupling. lambda(')(3jk). Each top squark decays to a tau lepton, a bottom quark, and two light quarks. Top squarks in this model with masses below 580 GeV are excluded at 95% confidence level. The constraint on the leptoquark mass is the most stringent to date, and this is the first search for top squarks decaying via. lambda(')(3jk). (C) 2014 The Authors. Published by Elsevier B. V.

Diagnosis of gastric cryptosporidiosis in birds using a duplex real-time PCR assay

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Rubella Vaccination of Unknowingly Pregnant Women: The Sao Paulo Experience, 2001

Background. Rubella vaccination is contraindicated during pregnancy. During mass immunization of women of childbearing age against rubella, women unknowingly pregnant may be vaccinated. To evaluate the effects of rubella vaccination during pregnancy, the Brazilian state of Sao Paulo conducted a follow-up study of pregnant women vaccinated during a rubella campaign in 2001.Methods. Women vaccinated during pregnancy were reported to a national surveillance system. In the state of Sao Paulo, follow-up of vaccinated women included household interviews. Serum samples from vaccinated women were tested for antirubella antibodies to classify susceptibility to rubella infection. Children born to susceptible mothers were tested for evidence of congenital rubella infection and evaluated for signs of congenital rubella syndrome.Results. The Sao Paulo State Health Department received 6473 notifications of women vaccinated during pregnancy. Serology performed for 5580 women identified 811 (15%) that were previously susceptible. Incidence of spontaneous abortion or stillbirth among previously susceptible vaccinated women was similar to women with prior immunity. Twenty-seven (4.7%) of 580 newborns tested had evidence of congenital rubella infection; none had congenital rubella syndrome.Conclusions. Mass rubella vaccination of women of childbearing age was not associated with adverse birth outcomes or congenital rubella syndrome among children born to women vaccinated during pregnancy.

Clinicopathologic features and outcome of mycophenolate-induced colitis in renal transplant recipients

Reports on the clinical course of mycophenolic acid (MPA)-related colitis in kidney transplant recipients are scarce. This study aimed at assessing MPA-related colitis incidence, risk factors, and progression after kidney transplantation. All kidney transplant patients taking MPA who had colonic biopsies for persistent chronic diarrhea, between 2000 and 2012, at the Kidney Transplantation Unit of Botucatu Medical School Hospital, Brazil, were included. Cytomegalovirus (CMV) immunohistochemistry was performed in all biopsy specimens. Data on presenting symptoms, medications, immunosuppressive drugs, colonoscopic findings, and follow-up were obtained. Of 580 kidney transplant patients on MPA, 34 underwent colonoscopy. Colonoscopic findings were associated with MPA usage in 16 patients. The most frequent histologic patterns were non-specific colitis (31.3%), inflammatory bowel disease (IBD)-like colitis (25%), normal/near normal (18.8%), graft-versus-host disease-like (18.8%), and ischemia-like colitis (12.5%). All patients had persistent acute diarrhea and weight loss. Six of the 16 MPA-related diarrhea patients (37.5%) showed acute dehydration requiring hospitalization. Diarrhea resolved when MPA was switched to sirolimus (50%), discontinued (18.75%), switched to azathioprine (12.5%), or reduced by 50% (18.75%). No graft loss occurred. Four patients died during the study period. Late-onset MPA was more frequent, and no correlation with MPA dose or formulation was found.

Water buffalo genome characterization by the Illumina BovineHD BeadChip

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Efeito de hipercabia no desenvolvimento de ovos de Trachemys scripta

Females of the painted turtle, Trachemys scripta, have an annual reproductive cycle. Their nest periods in Brazil starts around September and they lay about 7 - 10 eggs in nests dug in the soil. The eggs hatch in December. It is possible that the nest cover cause problems for the gas diffusion, also, the rain can wet or compact the soil covering the nest, or even soaked the whole area. Those problems may change the nests intern atmosphere decreasing O2 partial pressure (hypoxia) and increasing CO2 partial pressure (hypercarbia). The main objective of this study was to determine if and how hypercarbia (3% and 6%CO2), could influence the eggs and early posthatching development of the Trachemys scripta. We used three experimental groups of eggs incubated in: normal atmosphere (Control group CG, n = 14), hypercarbia with 3% of CO2 (G3%, n = 16) and with 6% of CO2 (G6%, n = 15). The profile of the mass increment during the egg development were not different among the groups, GC = 9.89±0.81g; G3% = 10.11±0.60g and G6% = 10.58±0.36g. In addition, the mass of the post-hatching turtles were the not different. There were not differences between the duration of the incubation period among the experimental groups, GC = 60.12±0.97days, G3% = 59.00±0.98days and G6% = 60.80±1.14days. The mortality rates were not affected by the hypercarbia, GC = 0.43 (43%), G3% = 0.27 (27%) and G6% = 0.37 (37%). Furthermore, the mass increment and the metabolic rate were the same among the early development of the turtles until 3 month after hatching. We conclude that hypercarbia (up to 6% of CO2) does not cause any alteration on the eggs or post-hatching normal development. It is possible that the combination of hypercarbia and hypoxia change those results

Aplicação de melhorias na organização e nos processos de usinagem pesada

Currently productivity is a concern in large firms and in heavy machining industries could not be otherwise . The issue of time in the process becomes a relevant and worthy of analysis point , especially that the setup time becomes a critical issue to be addressed . Due to the size of the equipment studied ( heavy machining ) and especially with regard to the characteristics of the machine tool and the parts to be machined , generally robust and large parts , the preparation of such parts shall be made accurately to the machining has a good result as planned . With the setup acting as a limiter of productivity growth in this sector , actions constantly in search of reducing downtimes and optimization are taken . This study aimed to conduct a study that confirms increased productivity by reducing the machining time , especially setup time and also with the implementation of organizational tools. Actions taken in heavy machining industry Arm L- 580 Liebherr company in Brazil specifically in CNC Boring PAMA Speedram 3000 were analyzed . Through a qualitative study using the method of case study , it was examined before and after the sector and reducing setup times . Evidencing the shares through figures and collection times . The end result of this analysis was to verify that through simple actions productivity and organization in the area were directly affected in a positive way , and supporting organizational change throughout training were taught to be incorporated into the company culture

Produção de celulases fúngicas por fermentação em estado sólido: ampliação de escala de biorreatores de leito fixo

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Length-weight relationship of 37 fish species from the Taquari River (Paranapanema Basin, Brazil)

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Effect of mucoadhesive polymers on the in vitro performance of insulin-loaded silica nanoparticles: Interactions with mucin and biomembrane models

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Source and frequency of dry season lipid supplementation of grazing, finishing cattle

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Hydrochemical and stable isotopes (H, O, S) signatures in deep groundwaters of Parana basin, Brazil

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

The glasgow prognostic score. An useful tool to predict survival in patients with advanced esophageal squamous cell carcinoma

To evaluate the usefulness of the Glasgow Prognostic Score (GPS) in patients with esophageal carcinoma (EC). A total of 50 patients with EC were analyzed for GPS, nutritional and clinicopathologic parameters. Patients with CRP ≤ 1.0mg/L and albumin ≥ 3.5mg/L were considered as GPS=0. Patients with only CRP increased or albumin decreased were classified as GPS=1 and patients with CRP > 1.0mg/L and albumin < 3.5mg/L were considered as GPS=2. GPS of 0, 1 and 2 were observed in seven, 23 and 20 patients, respectively. A significant inverse relationship was observed between GPS scores and the survival rate. The survival rate was greatest in patients with GPS= 0 and significantly higher than those from patients with GPS=1 and GPS=2. Minimum 12-month survival was observed in 71% patients with GPS=0 and in 30% patients with GPS=1. None of the patients with GPS=2 survived for 12 months. A significant relationship between CRP or albumin individually and the survival rate was observed. No significant relationship among nutritional, clinic pathological parameters and survival was found. Glasgow Prognostic Score is an useful tool to predict survival in patients with esophageal carcinoma.