992 resultados para Pratt, Daniel, 1799-1873.
Resumo:
dargest. von Paul Volz
Resumo:
[M. Roest]
Resumo:
The MET receptor tyrosine kinase is deregulated primarily via overexpression or point mutations in various human cancers and different strategies for MET inhibition are currently evaluated in clinical trials. We observed by Western blot analysis and by Flow cytometry that MET inhibition by different MET small molecule inhibitors surprisingly increases in a dose-dependent manner total MET levels in treated cells. Mechanistically, this inhibition-related MET accumulation was associated with reduced Tyr1003 phosphorylation and MET physical association with the CBL ubiquitin ligase with concomitant decrease in MET ubiquitination. These data may suggest careful consideration for design of anti-MET clinical protocols.
Resumo:
von Wolf Meyer Dessauer
Resumo:
hrsg. von dem israelitischen Lehrerverein in Ulm. Von Friedrich Pressel
Resumo:
[Hrsg.: David Gunzburg]
Resumo:
hrsg. von den Dozenten
Resumo:
Enth.: Verzeichnis der von 1873-1898 gehaltenen Vorlesungen