974 resultados para Paleography, Indo-Aryan.


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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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The effect of indomethacin (Indo), a cyclo-oxygenase inhibitor, on the monocyte-mediated killing of a low- (Pb265) and a high- (Pb18) virulence strain of Paracoccidioides brasiliensis was examined. The Pb18 strain was not killed by either non-activated or interferon-gamma (IFN-gamma) -activated human monocytes but these cells did show fungicidal activity if pretreated with Indo. In contrast with IFN-gamma, tumour necrosis factor-alpha (TNF-alpha) was very effective at stimulating the fungicidal activity of monocytes. While the low-virulence strain, Pb265, could not be killed by monocytes, cells preincubated with IFN-gamma demonstrated fungicidal activity. The killing of this strain was also induced by pretreatment of monocytes with Indo. The results suggest a negative role for prostaglandins, which are synthesized via the cyclo-oxygenase pathway, in the regulation of monocyte-mediated killing of virulent and avirulent strains of P. brasiliensis and that TNF-alpha generation during the fungus-monocyte interaction is more important in the killing of Pb265 than Pb18.

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This study had two objectives: to build theoretically the hypothetical landmarks of the environmental crisis and to conjecture new horizons or utopias which can fulfill themselves in the future in search of another being of the man in the world. Therefore, a bibliographic research has been done and, as methodology of analysis, a dialectic critical method has been used to understand the reality in its contradictions and in the totality of the history, through some suggestions, going toward the domain of the state of things which we can verify in the world nowadays. It has been observed that the hypothetical landmarks of the environmental crisis had and have its origins in the Jewish-Christian monotheism, in the exacerbation of the reason as the only way of knowledge and in the process of capitalist accumulation. Therefore, these landmarks, in almost their totality, have historically been built even before the advent of the capitalism. From this point, three suggestions were launched as questions, or so, possibilities, to open a discussion about the construction of another paradigm: Is it necessary another sense of religion? Is it necessary another sense of reason? Is it necessary another sense of sustainable development? Thus, these questions which have been launched, were thought as the current necessities for the environmental education and they implicate in another historical condition to the mankind.

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This paper will discuss some aspects of the problem of child sexual abuse, specifically incest, drawing on psychoanalysis and in particular the psychoanalytic proposed by Françoise Dolto allowing their concepts of castration simboligênica, symbolic function, image and body language unconsciously take incest as the object of study to propose a psychoanalytic clinic devoted to listening to the subject, going beyond the legal concerns of policies on reporting and complaints, but not meddle in them, reflecting on the role of the psychologist and psychoanalyst in the clinic for children of sexual abuse.

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You can set the resistance training such as making a move against a resistance by performing a muscle contraction and generating a muscular adaptation. This form of training, was initially used only in training athletes aiming to strengthen and improve fitness. Some coaches did not give proper focus, as the increase in muscle mass would cause loss of flexibility and agility. But over time a huge evolution occurred within this area and the practitioners of resistance training are no longer just athletes, and reached the whole community, from young to elderly, being a physical activity that generates a large caloric expenditure and has several health benefits, improve the cardiovascular system and decreasing the amount of body fat in the body. Cortisol is a hormone secreted from a stressful stimulus to the body, secretion undergoes control of the hypothalamic-pituitary axis, which releases the hormone into the bloodstream andrenocorticotrópico, going to the adrenal cortex responsible for their release. This has catabolic function, acting in the metabolism of carbohydrates, proteins and lipids, as well as having an important effect antiflamatório. Testosterone is a steroid hormone cholesterol from being produced by the testicles in men, as in women is produced to a lesser extent in ovary and adrenal glands, has functions androgenic and anabolic. Androgen function is responsible for the development of male sexual characteristics, while on anabolic function operates in the growth of muscles and bones, influencing the development of the human body organs. Within the metabolic changes that occur in the resistance training testosterone plays an important role in protein synthesis, influencing the production of strength and / or power during exercise. The objective of this work is through a literature review to assess the effects of resistance training on the production of these hormones and the relationship between them

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Pós-graduação em Educação Escolar - FCLAR

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O Desenvolvimento Sustentável tem sido pauta de diversos encontros globais que tentam solucionar as crises ambientais que vêm ocorrendo nas últimas décadas. Este trabalho tem como objetivo analisar as relações entre os impasses identificados na concepção de Desenvolvimento Sustentável e o modelo de desenvolvimento econômico capitalista tal como está configurado pelos princípios do neoliberalismo. Partimos da hipótese da inviabilidade do Desenvolvimento Sustentável em um sistema capitalista neoliberal. Utilizamos como metodologia de análise a cartografia, por meio da qual desenhamos as paisagens emergentes na dinâmica do poder ao indicar os limites do modelo de desenvolvimento econômico. Contrapomos as deficiências do modelo de desenvolvimento econômico com as premissas do que poderiam caracterizar o Desenvolvimento Sustentável. Desenvolvemos algumas reflexões acerca da sociedade de consumo e seus impactos na natureza. Apresenta-se as linhas de pensamento ecológico que discutem as maneiras de solucionar os problemas ambientais. Exercícios educacionais podem ser usados para a formação do compromisso de cada sujeito com a construção da comunidade. Refletir apenas nas contradições sociais não resolverá completamente a pressão exercida sobre os recursos naturais. A natureza não pode ser vista como um simples objeto estático que só se realiza a partir do trabalho humano, sua dinâmica deve ser considerada em sua totalidade. A sociedade não pode continuar a desenvolver meios de produção que aumentam a exploração da natureza. Uma nova estrutura social deve ser pensada, indo além das concepções marxistas e naturalistas, que promova justiça social e ambiental

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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

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The world's river dolphins (Inia, Pontoporia, Lipotes and Platanista) are among the least known and most endangered of all cetaceans. The four extant genera inhabit geographically disjunct river systems and exhibit highly modified morphologies, leading many cetologists to regard river dolphins as an unnatural group. Numerous arrangements have been proposed for their phylogenetic relationships to one another and to other odontocete cetaceans. These alternative views strongly affect the biogeographical and evolu- tionary implications raised by the important, although limited, fossil record of river dolphins. We present a hypothesis of river dolphin relationships based on phylogenetic analysis of three mitochondrial genes for 29 cetacean species, concluding that the four genera represent three separate, ancient branches in odontocete evolution. Our molecular phylogeny corresponds well with the first fossil appearances of the primary lineages of modern odontocetes. Integrating relevant events in Tertiary palaeoceanography, we develop a scenario for river dolphin evolution during the globally high sea levels of the Middle Miocene. We suggest that ancestors of the four extant river dolphin lineages colonized the shallow epicontinental seas that inundated the Amazon, Parana, Yangtze and Indo-Gangetic river basins, subsequently remaining in these extensive waterways during their transition to freshwater with the Late Neogene trend of sea-level lowering.

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O Desenvolvimento Sustentável tem sido pauta de diversos encontros globais que tentam solucionar as crises ambientais que vêm ocorrendo nas últimas décadas. Este trabalho tem como objetivo analisar as relações entre os impasses identificados na concepção de Desenvolvimento Sustentável e o modelo de desenvolvimento econômico capitalista tal como está configurado pelos princípios do neoliberalismo. Partimos da hipótese da inviabilidade do Desenvolvimento Sustentável em um sistema capitalista neoliberal. Utilizamos como metodologia de análise a cartografia, por meio da qual desenhamos as paisagens emergentes na dinâmica do poder ao indicar os limites do modelo de desenvolvimento econômico. Contrapomos as deficiências do modelo de desenvolvimento econômico com as premissas do que poderiam caracterizar o Desenvolvimento Sustentável. Desenvolvemos algumas reflexões acerca da sociedade de consumo e seus impactos na natureza. Apresenta-se as linhas de pensamento ecológico que discutem as maneiras de solucionar os problemas ambientais. Exercícios educacionais podem ser usados para a formação do compromisso de cada sujeito com a construção da comunidade. Refletir apenas nas contradições sociais não resolverá completamente a pressão exercida sobre os recursos naturais. A natureza não pode ser vista como um simples objeto estático que só se realiza a partir do trabalho humano, sua dinâmica deve ser considerada em sua totalidade. A sociedade não pode continuar a desenvolver meios de produção que aumentam a exploração da natureza. Uma nova estrutura social deve ser pensada, indo além das concepções marxistas e naturalistas, que promova justiça social e ambiental

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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

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This study documents one of the slowest feeding behaviors ever recorded for a muricid gastropod in one of the most biotically rigorous regions on the planet. In Pacific Panama, Vitularia salebrosa attacks mollusks by drilling through their shells. The duration of attacks estimated by isotope sclerochronology of oyster shells collected during attacks in progress range from 90 to 230 days, while experimental observation of interactions documented one attack greater than 103 days. The prolonged nature of attacks suggests that V. salebrosa is best characterized as an ectoparasite than as a predator, which is the ancestral condition in the Muricidae. An ectoparasitic lifestyle is also evident in the unusual interaction traces of this species, which include foot scars, feeding tunnels and feeding tubes, specialized soft anatomy, and in the formation of male-female Pairs, which is consistent with protandrous hermaphroditism, as is typical in sedentary gastropods. To delay death of its host, V. salebrosa targets renewable resources when feeding, such as blood and digestive glands. A congener, Vitularia miliaris from the Indo-Pacific, has an identical feeding biology The origin and persistence of extremely slow feeding in the tropics challenges our present understanding of selective pressures influencing the evolution of muricid feeding behaviors and morphological adaptations. Previously, it has been suggested that faster feeding is advantageous because it permits predators to spend a greater proportion of time hiding in enemy-free refugia or to take additional prey, the energetic benefits of which could be translated into increased fecundity or defenses. The benefits of exceptionally slow feeding have received little consideration. In the microhabitat preferred by V. salebrosa (beneath boulders), it is possible that prolonged interactions with hosts decrease vulnerability to enemies by reducing the frequency of risky foraging events between feedings . Ectoparasitic feeding through tunnels by V. salebrosa may also reduce competitive interactions with kleptoparasites (e.g., crabs, snails) that steal food through the gaped valves of dead or dying hosts.

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An anatomical description of two semelids from Thailand is presented, based on samples from Kungkrabaen Bay, Gulf of Thailand. The species are Semele sinensis A. Adams, 1853, and S. carnicolor (Hanley, 1845), both with Indo-Pacific distributions. Morphology in these two species is typically tellinoidean, each with a long internal ligamental element (resilium), a distance between the inner fold of the mantle edge and the other two folds, long and branched gastric ducts to the digestive diverticula, and a stomach diverticulum located in the posterodorsal corner of the gastric chamber, projecting posteriorly. The main anatomical differentiation between the two species is in the character of the labial palps.

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A revision of the deep-water verticordiid genus Spinosipella is provided, based on conchological and anatomical characters. The genus is considered distinct from Verticordia (of which it was considered a subgenus) based on the strong ribs, prickly surface, reduction of lunula, relative large size, weakly spiral valve shape, and other characters. The following species are considered in the genus: (1) Spinosipella agnes new species, ranging from Florida, USA, to Rio de Janeiro, Brazil, and also including the Porcupine Abyssal Plain in the North Atlantic; (2) S. tinga new species, occurring from Rio de Janeiro to Rio Grande do Sul, Brazil; (3) S. acuticostata (Philippi, 1844), a Pliocene fossil from southern Italy; (4) S. deshayesiana (Fischer, 1862), from south and central Indo-Pacific (S. ericia Hedley, 1911, the type species of the genus, was revealed to be a new synonym of S. deshayesiana); and (5) S. costeminens (Poutiers, 1981), from the tropical west Pacific. The five species differ mainly in conchological details of the number and size of ribs, of the prickly sculpture, shape of the shell, of the hinge and the degree of convexity. Anatomical description is also provided for the two Pacific species, which differ among themselves mainly by the size of the pair of renal folds. From the standpoint of anatomical characters, the more significant are: the wide lithodesma; the elongation of the auricles, crossing the roof of pallial cavity; a tall digital fold in posterior region of supraseptal chamber; the low but wide palps; the muscular, gizzard-like stomach; the complete separation of both constituents of the hermaphroditic gonad (a ventro-posterior testicle and a centro-dorsal ovary), and a complete fusion of the visceral ganglia.

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Dactylotrochus cervicornis (= Tridacophyllia cervicornis Moseley, 1881), which occurs in Indo-Pacific waters between 73 and 852 m, was originally described as an astraeid but was later transferred to the Caryophylliidae. Assumed to be solitary, this species has no stolons and only one elongated fossa, and is unique among azooxanthellate scleractinians in often displaying extremely long thecal extensions that are septate and digitiform. Based on both molecular phylogenetic analyses (partial mitochondrial CO1 and 16S rDNA, and partial nuclear 28S rDNA) and morphological characteristics, we propose the transfer of D. cervicornis from the Caryophylliidae to the Agariciidae, making it the first extant representative of the latter family that is solitary and from deep water (azooxanthellate). The basal position of D. cervicornis within the agariciids implied by our analyses strengthens the case for inclusion of fossil species that were solitary, such as Trochoseris, in this family and suggests that the ancestor of this scleractinian family, extant members of which are predominantly colonial and zooxanthellate, may have been solitary and azooxanthellate.