Investimento e financiamento: um enfoque sobre empresas de capital aberto

O objetivo do artigo é analisar os determinantes do investimento para uma amostra com 334 empresas no Brasil para o período de 1998 a 2000. As empresas foram selecionadas segundo o critério de liquidez acionário através do índice de negociabilidade de 1998 da Bolsa de Valores de São Paulo, que aponta o grau de liquidez das ações. Com isso, procuramos contribuir para o entendimento do financiamento das empresas no Brasil em condições de instabilidade macroeconômica.

Demographic determinants of survival of people living with HIV attending an outpatient reference unit in the city of Três Lagoas, state of Mato Grosso do Sul, Brazil, in the period 1984-2009

,,,,,,,,,, While the incidence of HIV infection and AIDS is increasing in small Brazilian cities, epidemiological studies are often conducted in large urban centers. ,,,,,,,,,,,,,,,,,, Our group conducted a retrospective analysis of survival determinants among 358 patients who attended a reference unit in a small city.,,,,,,,,,,,,,,,,,,,,,,,Death risk was lower among men that had sex with men, patients with an HIV-seropositive partner, and those admitted after highly active antiretroviral therapy (HAART) was available. ,,,,,,,,,,,,,,,,,, The study documents the striking beneficial effect of HAART. The finding of other groups with improved survival may aid in the development of programmatic strategies.,,,,

Molecular determinants of binding of a wasp toxin (PMTXs) and its analogs in the Na+ channels proteins

The structural specificity of alpha-PMTX, a novel peptide toxin derived from wasp venom has been studied on the neuromuscular synapse in the walking leg of the lobster. alpha-PMTX is known to induce repetitive action potentials in the presynaptic axon due to sodium channel inactivation. We synthesized 29 analogs of alpha-PMTX by substituting one or two amino acids and compared threshold concentrations of these mutant toxins for inducing repetitive action potentials. In 13 amino acid residues of alpha-PMTX, Arg-1, Lys-3 and Lys-12 regulate the toxic activity because substitution of these basic amino acid residues with other amino acid residues greatly changed the potency. Determining the structure-activity relationships of PMTXs will help clarifying the molecular mechanism of sodium channel inactivation. (C) 2000 Elsevier B.V. Ireland Ltd. All rights reserved.

Interference phenomenon for the Faddeevian regularization of 2D chiral fermionic determinants

The classification of the regularization ambiguity of a 2D fermionic determinant in three different classes according to the number of second-class constraints, including the new Faddeevian regularization, is examined and extended. We find a new and important result that the Faddeevian class, with three second-class constraints, possesses a free continuous one parameter family of elements. The criterion of unitarity restricts the parameter to the same range found earlier by Jackiw and Rajaraman for the two-constraint class. We studied the restriction imposed by the interference of right-left modes of the chiral Schwinger model (χQED2) using Stone's soldering formalism. The interference effects between right and left movers, producing the massive vectorial photon, are shown to constrain the regularization parameter to belong to the four-constraint class which is the only nonambiguous class with a unique regularization parameter. ©1999 The American Physical Society.

A new firefly luciferase with bimodal spectrum: Identification of structural determinants of spectral pH-sensitivity in firefly luciferases

Fireflies emit flashes in the green-yellow region of the spectrum for the purpose of sexual attraction. The bioluminescence color is determined by the luciferases. It is well known that the in vitro bioluminescence color of firefly luciferases can be shifted toward the red by lower pH and higher temperature; for this reason they are classified as pH-sensitive luciferases. However, the mechanism and structural origin of pH sensitivity in fireflies remains unknown. Here we report the cloning of a new luciferase from the Brazilian twilight active firefly Macrolampis sp2, which displays an unusual bimodal spectrum. The recombinant luciferase displays a sensitive spectrum with the peak at 569 nm and a shoulder in the red region. Comparison of the bioluminescence spectra of Macrolampis, Photinus and Cratomorphus firefly luciferases shows that the distinct colors are determined by the ratio between green and red emitters under luciferase influence. Comparison of Macrolampis luciferase with the highly similar North American Photinus pyralis luciferase (91%) showed few substitutions potentially involved with the higher spectral sensitivity in Macrolampis luciferase. Site-directed mutagenesis showed that the natural substitution E354N determines the appearance of the shoulder in the red region of Macrolampis luciferase bioluminescence spectrum, helping to identify important interactions and residues involved in the pH-sensing mechanism in firefly luciferases. © 2005 American Society for Photobiology.

Economic Survey of Latin America and the Caribbean 2010-2011: Internacional integration and macroeconomic policy challenges amid global economic turmoil

Includes bibliography

Macroeconomic Report on Latin America and the Caribbean. June 2012

Incluye Bibliografía

Beyond reforms: structural dynamics and macroeconomic vulnerability

Includes bibliography

Export growth in Latin America: policies and performance

Includes bibliography

From capital surges to drought: seeking stability for emerging economies

Includes bibliography