Mental culture, or, The means of developing the human faculties /

Mode of access: Internet.

Education, the birthright of every human being : and the only scriptural preparation for the millenium : exhibiting the present imperfect state of popular instruction, and the means of rendering it effectual for the salvation of the country and the world /

Goldsmiths'-Kress no. 34397.

Immediate, not gradual abolition, or, An inquiry into the shortest, safest, and most effectual means of getting rid of West Indian slavery.

Goldsmiths'-Kress no. 24317.

An historical and practical treatise upon elemental locomotion, by means of steam carriages on common roads : showing ... the rise, progress, and description of steam carriages; the roads upon which they may be made to travel ... /

Mode of access: Internet.

Observations on the best means of propelling ships.

Mode of access: Internet.

Immediate, not gradual abolition: or, An inquiry into the shortest, safest, and most effectual means of getting rid of West Indian slavery.

First published in England, 1824.

Adam's Latin grammar, simplified, by means of an introduction: designed to facilitate the study of Latin grammar...with appropriate exercises, to impress on the memory the declensions and inflections of the parts of speech, and to exemplify and illustrate the rules of syntax.

Mode of access: Internet.

The complete cost-keeper; some original systems of shop cost-keeping or factory accounting, together with an exposition of the advantages of account keeping by means of cards instead of books.

Mode of access: Internet.

Excelsior; or, Essays on politeness, education, and the means of attaining success in life ...

pt. I. For young gentlemen, by T. E. Howard.--pt. II. For young ladies, by a lady, (R. V. R.)

Sneak circuit analysis : a means of verifying design integrity.

"July 1986."

Diarrhæa and cholera : their origin, proximate cause, and cure, through the agency of the nervous system by means of ice /

Publisher's press listings.

Non-additivity of attractive potentials in modeling of N-2 and Ar adsorption isotherms on graphitized carbon black and porous carbon by means of density functional theory

We present a new approach accounting for the nonadditivity of attractive parts of solid-fluid and fluidfluid potentials to improve the quality of the description of nitrogen and argon adsorption isotherms on graphitized carbon black in the framework of non-local density functional theory. We show that the strong solid-fluid interaction in the first monolayer decreases the fluid-fluid interaction, which prevents the twodimensional phase transition to occur. This results in smoother isotherm, which agrees much better with experimental data. In the region of multi-layer coverage the conventional non-local density functional theory and grand canonical Monte Carlo simulations are known to over-predict the amount adsorbed against experimental isotherms. Accounting for the non-additivity factor decreases the solid-fluid interaction with the increase of intermolecular interactions in the dense adsorbed fluid, preventing the over-prediction of loading in the region of multi-layer adsorption. Such an improvement of the non-local density functional theory allows us to describe experimental nitrogen and argon isotherms on carbon black quite accurately with mean error of 2.5 to 5.8% instead of 17 to 26% in the conventional technique. With this approach, the local isotherms of model pores can be derived, and consequently a more reliab * le pore size distribution can be obtained. We illustrate this by applying our theory against nitrogen and argon isotherms on a number of activated carbons. The fitting between our model and the data is much better than the conventional NLDFT, suggesting the more reliable PSD obtained with our approach.

Engineering stable peptide toxins by means of backbone cyclization: Stabilization of the alpha-conotoxin MII

Conotoxins (CTXs), with their exquisite specificity and potency, have recently created much excitement as drug leads. However, like most peptides, their beneficial activities may potentially be undermined by susceptibility to proteolysis in vivo. By cyclizing the alpha-CTX MII by using a range of linkers, we have engineered peptides that preserve their full activity but have greatly improved resistance to proteolytic degradation. The cyclic MII analogue containing a seven-residue linker joining the N and C termini was as active and selective as the native peptide for native and recombinant neuronal nicotinic acetylcholine receptor subtypes present in bovine chromaffin cells and expressed in Xerl oocytes, respectively. Furthermore, its resistance to proteolysis against a specific protease and in human plasma was significantly improved. More generally, to our knowledge, this report is the first on the cyclization of disulfide-rich toxins. Cyclization strategies represent an approach for stabilizing bioactive peptides while keeping their full potencies and should boost applications of peptide-based drugs in human medicine.

Adsorption of flexible n-alkane on graphitized thermal carbon black: analysis of adsorption isotherm by means of GCMC simulation

In this paper, we investigate the suitability of the grand canonical Monte Carlo in the description of adsorption equilibria of flexible n-alkane (butane, pentane and hexane) on graphitized thermal carbon black. Potential model of n-alkane of Martin and Siepmann (J. Phys. Chem. 102 (1998) 2569) is employed in the simulation, and we consider the flexibility of molecule in the simulation. By this we study two models, one is the fully flexible molecular model in which n-alkane is subject to bending and torsion, while the other is the rigid molecular model in which all carbon atoms reside on the same plane. It is found that (i) the adsorption isotherm results of these two models are close to each other, suggesting that n-alkane model behaves mostly as rigid molecules with respect to adsorption although the isotherm for longer chain n-hexane is better described by the flexible molecular model (ii) the isotherms agree very well with the experimental data at least up to two layers on the surface.