898 resultados para Heart of Darkness
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A introdução de negros submetidos ao cativeiro na Capitania de Mato Grosso decorreu da descoberta das minas de Cuiabá. A crise da mineração deslocou os capitais utilizados na mineração para outros setores, ou seja, Mato Grosso passava, no começo do século XIX, por uma fase de transição da economia mineradora para a agropastoril. Nesse período, uma onda povoadora oriunda de Minas Gerais e São Paulo, alcançou o núcleo de Sant’Ana do Paranaíba e dali se expandiu para grande parte do sudeste do antigo Mato Grosso, valendo-se amplamente do braço escravizado para suas incursões, apossamentos e desenvolvimento econômico. Este texto busca compreender as relações escravistas em Sant’Ana de Paranaíba, bem como o papel do escravo naquela sociedade.
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Pós-graduação em Letras - IBILCE
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BACKGROUND: Intervention studies have shown an increased mortality in patients who received beta-carotene. However, the mechanisms involved in this phenomenon are still unknown. OBJECTIVE: Evaluate the influence of beta-carotene on oxidative stress and the expression of connexin 43 in rat hearts. METHODS: Wistar rats, weighing approximately 100 g, were allocated in two groups: Control Group (n=30), that received the diet routinely used in our laboratory, and Beta-Carotene Group (n = 28), which received beta-carotene (in crystal form, added and mixed to the diet) at a dose of 500 mg of beta-carotene/kg of diet. The animals received the treatment until they reached 200-250g, when they were sacrificed. Samples of blood, liver and heart were collected to perform Western blotting and immunohistochemistry for connexin 43; morphometric studies, dosages of beta-carotene by high-performance liquid chromatography as well as reduced glutathione, oxidized glutathione and lipids hydroperoxides were performed by biochemical analysis. RESULTS: Beta-carotene was detected only in the liver of Beta-Carotene Group animals (288 ± 94.7 µg/kg). Levels of reduced/oxidized glutathione were higher in the liver and heart of Beta-Carotene Group animals (liver - Control Group: 42.60 ± 1.62; liver - Beta-Carotene Group: 57.40 ± 5.90; p = 0.04; heart: - Control Group: 117.40 ± 1.01; heart - Beta-Carotene Group: 121.81 ± 1.32 nmol/mg protein; p = 0.03). The content of total connexin 43 was larger in Beta-Carotene Group. CONCLUSION: Beta-carotene demonstrated a positive effect, characterized by the increase of intercellular communication and improvement of anti-oxidizing defense system. In this model, mechanism does not explain the increased mortality rate observed with the beta-carotene supplementation in clinical studies. (Arq Bras Cardiol. 2013; [online].ahead print, PP.0-0)
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Pós-graduação em Geografia - IGCE
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
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Pós-graduação em Ciência e Tecnologia Animal - FEIS
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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The heart of the insect is essentially myogenic, in others words, electrical activity and spontaneous contractions are generated by their muscle cells. However, the nature of pacemaker activity is not yet fully elucidated. One aspect that deserves attention, beyond the pacemaker activity, is the amplitude of heart contractions of the insect. For this, it is necessary that the heart to be stimulated electrically to the frequency to be controlled. In the present work, it was developed a method of stimulation (preparation and instrumentation). The contractile activity of the heart of the insect remained regular when stimulated at frequencies lightly above the spontaneous frequency. To characterize excitability of the preparation the intensity-duration curve was determined
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This project addresses the importance of Public Relations as an agent capable of working towards balance and constant search for consensus in order to minimize potential conflicts of interest concerning diversity within organizations. It aims to engage the issues of power relations, believing that they permeate the entire act in society and also for being human relationships at the heart of the work of Public Relations
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This work is the result of previous studies, such as the undergraduate research project and the “Núcleo de Ensino” project, which were based on knowledge of young residents of Presidente Prudente - SP. The present study aims to interpret and understand the ways the students experience the school and the city. To get results we studied the high school students of State School Fernando Costa, known as IE, located in the heart of the city. The research development came from the Participant Observation, after the use of questionnaires, interviews and finally the completion of a Focus Group. Finally, there is the consideration of the material collected in the practice, their school experiences and City entertainment. Following the conclusions drawn from this study
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
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In this essay, we sustain the idea that structuralist thinking is part of spontaneous criticism against the reductionisms that surround psychology. We depart from the radical split-up between the scientific viewpoint and that of metaphysics, expressed in the end-19th century scientific psychology projects. Next, we highlight the importance of the structuralist perspective in the review of the antinomic relations between the subjective and objective, operated at the heart of psychology throughout the 20th century. We show that the rejection of unilineal causality in favor of network causality curbed the advancement of unilateral or reductionist theories in psychology. Moreover, we consider the idea of structure as a point of convergence between psychology and philosophy. More than its explanatory nature, the notion of structure reveals an epistemological register capable of re-approximating psychology to the relativization of the ideal of scientific neutrality. The importance of structuralist thinking in psychology makes us consider the history of psychological knowledge as a type of research that belongs to cultural history.
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)