Can publicly available webcameras and mechanical Turks be used to evaluate physical activity policy and built environment change?

Introduction: Fewer than 50% of adults and 40% of youth meet US CDC guidelines for physical activity (PA) with the built environment (BE) a culprit for limited PA. A challenge in evaluating policy and BE change is the forethought to capture a priori PA behaviors and the ability to eliminate bias in post-change environments. The present objective was to analyze existing public data feeds to quantify effectiveness of BE interventions. The Archive of Many Outdoor Scenes (AMOS) has collected 135 million images of outdoor environments from 12,000 webcams since 2006. Many of these environments have experienced BE change. Methods: One example of BE change is the addition of protected bike lanes and a bike share program in Washington, DC.Weselected an AMOS webcam that captured this change. AMOS captures a photograph from eachwebcamevery half hour.AMOScaptured the 120 webcam photographs between 0700 and 1900 during the first work week of June 2009 and the 120 photographs from the same week in 2010. We used the Amazon Mechanical Turk (MTurk) website to crowd-source the image annotation. MTurk workers were paid US$0.01 to mark each pedestrian, cyclist and vehicle in a photograph. Each image was coded 5 unique times (n=1200). The data, counts of transportation mode, was downloaded to SPSS for analysis. Results: The number of cyclists per scene increased four-fold between 2009 and 2010 (F=36.72, p=0.002). There was no significant increase in pedestrians between the two years, however there was a significant increase in number of vehicles per scene (F=16.81, p

Single and double photoionization of Be and Mg

A new version of the time-dependent close-coupling method is used to calculate the single and double photoionization of the Be and Mg atoms. Total cross sections are calculated using an implicit time propagator with a core orthogonalization method on a variable radial mesh. The double to single photoionization cross section ratios are found to be in good agreement with experiment for both Be and Mg.

Generalized collisional radiative model for light elements. Part B: Data for the Be isonuclear sequence

A first-stage collision database is assembled which contains electron-impact excitation, ionization, and recombination rate coefficients for Be, Be+, Be2+, and Be3+. The first-stage database is constructed using the R-matrix with pseudo-states, time-dependent close-coupling, and perturbative, distorted-wave methods. A second-stage collision database is then assembled which contains generalized collisional-radiative and radiated power loss coefficients. The second-stage database is constructed by solution of collisional-radiative equations in the quasi-static equilibrium approximation using the first-stage database. Both collision database stages reside in electronic form at the ORNL Controlled Fusion Atomic Data Center and in the ADAS database, and are easily accessed over the worldwide internet. © 2007 Elsevier Inc. All rights reserved.

Inner-shell photodetachment of excited 4S° and 6S° metastable bound states of Be-

The total cross sections for photodetachment of the metastable 1s ²2p^{3 4}S° and 1s2s2p^{3 6}S° excited bound states of the negative ion of beryllium are presented for a range of initial photon energies across and beyond the 1s detachment threshold. A multichannel close-coupling R-matrix approximation is used to compute the cross sections, with sophisticated configuration-interaction wavefunctions being used to represent the initial and final states. At present there are no other theoretical or experimental data available with which to compare the cross sections for these two photodetachment processes.

Can Future Managers and Business Executives be Influenced to Behave more Ethically in the Workplace? The Impact of Approaches to Learning on Business Students’ Cheating Behavior

This study considers the potential for influencing business students to become ethical managers by directing their undergraduate learning environment. In particular, the relationship between business students’ academic cheating, as a predictor of workplace ethical behavior, and their approaches to learning is explored. The three approaches to learning identified from the students’ approaches to learning literature are deep approach, represented by an intrinsic interest in and a desire to understand the subject, surface approach, characterized by rote learning and memorization without understanding, and strategic approach, associated with competitive students whose motivation is the achievement of good grades by adopting either a surface or deep approach. Consistent with the hypothesized theoretical model, structural equation modeling revealed that the surface approach is associated with higher levels of cheating, while the deep approach is related to lower levels. The strategic approach was also associated with less cheating and had a statistically stronger influence than the deep approach. Further, a significantly positive relationship reported between deep and strategic approaches suggests that cheating is reduced when deep and strategic approaches are paired. These findings suggest that future managers and business executives can be influenced to behave more ethically in the workplace by directing their learning approaches. It is hoped that the evidence presented may encourage those involved in the design of business programs to implement educational strategies which optimize students’ approaches to learning towards deep and strategic characteristics, thereby equipping tomorrow’s managers and business executives with skills to recognize and respond appropriately to workplace ethical dilemmas.

Immune-derived PD-L1 gene expression defines a subgroup of stage II/III colorectal cancer patients with favorable prognosis that may be harmed by adjuvant chemotherapy

A recent phase 2 study of metastatic colorectal carcinoma (CRC) patients showed that mismatch repair gene status was predictive of clinical response to PD-1-targeting immune checkpoint blockade. Further examination revealed strong correlation between PD-L1 protein expression and microsatellite instability (MSI) in stage IV CRC, suggesting that the amount of PD-L1 protein expression could identify late stage patients who may benefit from immunotherapy. To assess whether the clinical associations between PD-L1 gene expression and MSI identified in metastatic CRC are also present in stage II/III CRC, we used in silico analysis to elucidate the cell types expressing the PD-L1 gene. We found a significant association of PD-L1 gene expression with MSI in early stage CRC (P < 0.001) and show that unlike in non-CRC tumors, PD-L1 is derived predominantly from the immune infiltrate. We demonstrate that PD-L1 gene expression has positive prognostic value in the adjuvant disease setting (PD-L1low v PD-L1high HR = 9.09; CI, 2.11-39.10). PD-L1 gene expression had predictive value, as patients with high PD-L1 expression appear to be harmed by standard-of-care treatment (HR = 4.95; CI,1.10-22.35). Building on the promising results from the metastatic CRC PD-1-targeting trial, we provide compelling evidence that PD-L1high/MSI/immunehigh stage II/III CRC patients should not receive standard chemotherapy. This conclusion supports the rationale to clinically evaluate this patient subgroup for PD-1 blockade treatment.

Scholarly chronographics: can a timeline be useful in historiography?

Our paper is concerned with the visualisation of historical events and artefacts in the context of time. It arises from a project bringing together expertise in visualisation, historiography and software engineering. The work is the result of an extended enquiry over several years which has included investigation of the prior history of such chronographics and their grounding in the temporal ontology of the Enlightenment. Timelines - visual, spatial presentations of chronology - are generally regarded as being too simple, perhaps too childish, to be worthy of academic attention, yet such chronographics should be capable of supporting sophisticated thinking about history and historiography, especially if they take full advantage of the capabilities of digital technologies. They should enable even professional academic historians to 'make sense' of history in new ways, allowing them insights they would not otherwise have achieved. In our paper we highlight key findings from the history of such representations, principally from the eighteenth and nineteenth centuries, and show how, in a project to develop new digital chronographics for collections of cultural objects and events, we have explored new implementations of the important ideas we have extracted about timewise presentation and interaction. This includes the representation of uncertainty, of relations between events, and the epistemology of time as a 'space' for history. We present developed examples, in particular a chronographic presentation of a large database of works by a single author, a composer, and discuss the extent to which our ambitions for chronographics have been realised in practice. Keywords: timeline, chronographics

“Should we all be on Marx’s side?” Contributions of post-marxist discourse theory to the historiography of communism

Drawing on post-marxist discourse theory inspired by the writings of Ernesto Laclau and Chantal Mouffe, this article puts the case for a literature on communism situated at the crossroads of critical theory, cultural studies and historiography. Specific illustration is provided by the author's own research on British communism and the Spanish Civil War. However, the scope of the article is much broader and it is intended as a contribution to the theoretical discussion of future possibilities for communist history-writing. The article concludes that discourse should be regarded neither as a flat surface of tightly knit signifiers nor as an impenetrable monolith of meaning systems. Rather, it should be seen as an inherently dynamic phenomenon, with its own condensations and dispersions along the historical continuum. In this lies its significance for historians of communism.

How to Be Happy: A Novel

Thesis (Master's)--University of Washington, 2013

Can illusory deviant stimuli be used as attentional distractors to record vMMN in a passive three stimulus oddball paradigm?

A passive three stimulus oddball paradigm was used to investigate Visual Mismatch Negativity (vMMN) a component of the Event Related Potential (ERP) believed to represent a central pre-attentive change mechanism. Responses to a change in orientation were recorded to monochrome stimuli presented to subjects on a computer screen. One of the infrequent stimuli formed an illusory figure (Kanizsa Square) aimed to capture spatial attention in the absence of an active task. Nineteen electrodes (10-20 system) were used to record the electroencephalogram in fourteen subjects (ten females) mean age 34.5 years. ERPs to all stimuli consisted of a positive negative positive complex recorded maximally over lateral occipital areas. The negative component was greater for deviant and illusory deviant compared to standard stimuli in a time window of 170-190 ms. A P3a component over frontal/central electrodes to the illusory deviant but not to the deviant stimulus suggests the illusory figure was able to capture attention and orientate subjects to the recording. Subtraction waveforms revealed visual discrimination responses at occipital electrodes, which may represent vMMN. In a control study with 13 subjects (11 females; mean age 29.23 years), using an embedded active attention task, we confirmed the existence of an earlier (150-170 ms) and attenuated vMMN. Recordings from an intracranial case study confirmed separation of N1 and discrimination components to posterior and anterior occipital areas, respectively. We conclude that although the illusory figure captured spatial attention in its own right it did not draw sufficient attentional resources from the standard-deviant comparison as revealed when using a concurrent active task.

Choosing to be Jews: a Sociological Reflection on American Jews Since 1950, pt. 1

The second half of the twentieth century has been a time when American Jews have experienced a minimum of prejudice and almost all domains of life have been accessible to them, but it has also been a time of assimilation, of swelling rates of inter-marriage, and of large numbers ignoring their Jewishness completely. Jews have no trouble building synagogues, but they have all sorts of trouble filling them. The quality of Jewish education is perhaps higher than ever before, and the output of Jewish scholarship is overwhelming in its scope and quality, but most American Jews receive a minimum of religious education and can neither read nor comprehend the great corpus of Jewish literature in its Hebrew (or Aramaic) original. This is a time in America when there is no shame in being a Jew, and yet fewer American Jews seem to know what being a Jew means. This book is part of a stocktaking that has been occurring among Jews as the century in which their residence in America was firmly established comes to an end. Grounded in empirical detail, it provides a concise yet analytic evaluation of the meaning of the many studies and surveys of the last four and a half decades. All those who want to know what it means and has meant to be an American Jew will find this volume of interest.

Choosing to be Jews: a Sociological Reflection on American Jews Since 1950, pt. 2

The second half of the twentieth century has been a time when American Jews have experienced a minimum of prejudice and almost all domains of life have been accessible to them, but it has also been a time of assimilation, of swelling rates of inter-marriage, and of large numbers ignoring their Jewishness completely. Jews have no trouble building synagogues, but they have all sorts of trouble filling them. The quality of Jewish education is perhaps higher than ever before, and the output of Jewish scholarship is overwhelming in its scope and quality, but most American Jews receive a minimum of religious education and can neither read nor comprehend the great corpus of Jewish literature in its Hebrew (or Aramaic) original. This is a time in America when there is no shame in being a Jew, and yet fewer American Jews seem to know what being a Jew means. This book is part of a stocktaking that has been occurring among Jews as the century in which their residence in America was firmly established comes to an end. Grounded in empirical detail, it provides a concise yet analytic evaluation of the meaning of the many studies and surveys of the last four and a half decades. All those who want to know what it means and has meant to be an American Jew will find this volume of interest.

Choosing to be Jews: a Sociological Reflection on American Jews Since 1950, pt. 3

The second half of the twentieth century has been a time when American Jews have experienced a minimum of prejudice and almost all domains of life have been accessible to them, but it has also been a time of assimilation, of swelling rates of inter-marriage, and of large numbers ignoring their Jewishness completely. Jews have no trouble building synagogues, but they have all sorts of trouble filling them. The quality of Jewish education is perhaps higher than ever before, and the output of Jewish scholarship is overwhelming in its scope and quality, but most American Jews receive a minimum of religious education and can neither read nor comprehend the great corpus of Jewish literature in its Hebrew (or Aramaic) original. This is a time in America when there is no shame in being a Jew, and yet fewer American Jews seem to know what being a Jew means. This book is part of a stocktaking that has been occurring among Jews as the century in which their residence in America was firmly established comes to an end. Grounded in empirical detail, it provides a concise yet analytic evaluation of the meaning of the many studies and surveys of the last four and a half decades. All those who want to know what it means and has meant to be an American Jew will find this volume of interest.