Dimensionamento e realizzazione delle pavimentazioni rigide aeroportuali. Caso di studio: interventi di riqualifica delle infrastrutture di volo dell'aeroporto "Marco Polo" di Tessera - Venezia.

Il presente elaborato ha come oggetto l’analisi e lo studio delle teorie di calcolo degli stati tensionali e deformativi delle lastre in calcestruzzo e dei metodi di progettazione delle pavimentazioni rigide aeroportuali, le quali sono state applicate al caso specifico degli interventi di riqualifica e adeguamento delle infrastrutture di volo dell’Aeroporto “Marco Polo” di Tessera – Venezia. Sono state descritte le principali fasi realizzative della pavimentazione rigida dell’Apron Sud del suddetto aeroporto ed analizzati i risultati delle prove di caratterizzazione del calcestruzzo, in fase preliminare e in corso d’opera, e delle prove di valutazione della capacità portante della sovrastruttura ultimata.

Retrospective evaluation of the effects of administration of tetrastarch (hydroxyethyl starch 130/0.4) on plasma creatinine concentration in dogs (2010-2013): 201 dogs

OBJECTIVE To determine changes in creatinine concentrations following the administration of 6% tetrastarch (hydroxyethyl starch [HES] 130/0.4) compared to crystalloids (CRYSs) in critically ill dogs. DESIGN Retrospective case series (2010-2013). SETTING University teaching hospital. ANIMALS Two hundred and one dogs admitted to the intensive care unit with initial plasma creatinine concentrations not exceeding laboratory reference intervals (52-117 μmol/L [0.6-1.3 mg/dL]) and receiving either CRYSs alone (CRYS group, n = 115) or HES with or without CRYSs (HES group, n = 86) for at least 24 hours. INTERVENTIONS None. MEASUREMENTS AND MAIN RESULTS Creatinine concentrations at admission to the intensive care unit (T0), and 2-13 days (T1) and 2-12 weeks (T2) after initiation of fluid therapy were analyzed. Creatinine concentrations were analyzed as absolute values and as the maximum percentage change from T0 to T1 (T1max%) and from T0 to T2 (T2max%), respectively. Creatinine concentrations were available for 192 dogs during T1 and 37 dogs during T2. The median cumulative dose of HES was 86 mL/kg (range, 12-336 mL/kg). No difference was detected between the groups for age, gender, body weight, and length of hospitalization. Outcome was significantly different between the HES (66% survived) and the CRYS (87% survived) groups (P = 0.014). No significant difference was detected between groups for creatinine concentrations at T0, T1, T2, T1max%, or T2max%. No significant difference was detected between the groups for T1max% creatinine in dogs subclassified as having systemic inflammatory response syndrome or sepsis. CONCLUSIONS HES administration in this canine population did not result in increased creatinine concentrations compared to administration of CRYSs. Further studies are needed to establish the safety of HES in critically ill dogs.

Drug-induced torsades de pointes in an underserved urban population. Methadone: is there therapeutic equipoise?

BACKGROUND Although it has been well established that methadone use can result in prolonged QTc/torsades de pointes (TdP) and has been labeled as one of the main drugs that cause TdP, it is still prescribed indiscriminately, and several cases of methadone-associated TdP have been seen in our community. METHODS Our objective was to determine the associated factors for prolonged QTc and the development of torsades de pointes (TdP) in our underserved patient population. We found 12,550 ECGs with prolonged QTc between 2002 and 2013. Medical records were reviewed in order to identify precipitating factors for prolonged QTc and to detect incidence of TdP. RESULTS We identified 2735 patients with prolonged QTc who met the inclusion criteria. Of these, 89 (3%) experienced TdP. There was a greater prevalence of HIV infection in the TdP group (11.2 vs. 3.7%, p < 0.001). Furosemide, hydrochlorothiazide, selective serotonin reuptake inhibitors (SSRIs), amiodarone, ciprofloxacin, methadone, haloperidol, and azithromycin were the drugs most often associated with prolonged QTc (31, 8.2, 7.6, 7.1, 3.9, 3.4 and 3.3%, respectively). However, the agents most commonly associated with TdP were furosemide (39.3%), methadone (27%), SSRIs (19.1%), amiodarone (18%), and dofetilide (9%). The medications with statistical significance in the multivariate analysis for TdP development in descending order were as follows: ranolazine (odds ratios [OR] = 53.61, 95% confidence interval [CI] 5.4-524, p < 0.001), dofetilide (OR = 25, CI 6.47-103.16, p < 0.001), voriconazole (OR = 21.40, CI 3.24-124.25, p < 0.001), verapamil (OR = 10.98, CI 2.62-44.96, p < 0.001), sotalol (OR = 12.72, 1.95-82.81, p = 0.008), methadone (OR = 9.89, CI 4.05-24.15, p < 0.001), and SSRI (OR = 2.26, CI 1.10-5.96, p < 0.001). This multivariate analysis revealed that amiodarone and HIV infection were not implicated in TdP. CONCLUSION Methadone was by far the leading medication implicated in the development of TdP and an independent predictor in both univariate and multivariate analyses despite the fact that it was not the most common QT-prolonging medication in our population.

Le antiche iscrizioni di Palermo : raccolte, e spiegate sotto gli auspizj dell' eccellentissimo Senato palermitano, grande di Spagna di prima classe.

Includes indexes.

Lo stato presente di tutti i paesi e popoli del mondo naturale, politico e morale : con nuove osservazioni e correzioni degli antichi, e moderni viaggiatori.

Mode of access: Internet.

Le rime di M. Francesco Petrarca : riscontrate con ottimi esemplari stampati, e con somma diligenza corrette, con la tavola di tutte le rime del Canzoniere ridotte coi versi interi sotto le lettere vocali.

Sonetti e canzoni di M. Francesco Petrarca in vita e in morte di M. Laura (p.1-264) ; Trionfi di M. Francesco Petrarca (p.265-324) ; Giunta d'alcune composizioni del Petrarca (p.325-373)

Rime di Torquato Tasso, di nuovo corrette ed illustrate ...

"Orazione in lode di Torquato Tasso, fatta nell' Accademia degli Alterati in Firenze da Lorenzo Giacomini Tebalducci Malespini": v. 5, p. [75]-115.

Decamerone di Messer Giovanni Boccaccio.

"Indice delle voci antiche, oscure, di più significati, &c [comp. da C. Malanima]" v. 4, p. 271-312.

I sonetti, le canzoni, et i triomphi di m. Lavra in risposta di m. Francesco Petrarcha : per le sve Rime in vita, et dopo la morte di lei /

"Quest opera fu veramente fatica, non già di Laura, ma di esso Stefano Colonna; come si leggeva in un testo a penna allegato da' postillatori del Cresimbeni (Quadrio, t. II, p. 241)"--Melzi, Dizionario di opere anonime, t. II (1852) p. 70.

Prose di Feo Belcari edite ed inedite sopra autografi e testi a penna,

Original works and translations; each work has special t.-p.

Lettere di Francesco Redi ...

"Elogio di Francesco Redi," signed Domenico Brogiani: v. 1., p. xxxviii-xlv.

Lettere di Feo Belcari.

Life and works of Feo Belcari: p. xiv-xlviii.

Istorie fiorentine di Scipione Ammirato ...

"Opere di Scipione Ammirato stampate": v. 11, p. [lx]-lxiv.

Opere di Pietro Metastasio.

Vol. 16 includes general index (p. [361]-366)

Poesie di Ossian,

Includes critical dissertations by Hugh Blair, P. L. Ginguené and the translator.