920 resultados para mild cognitive impairment


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Humans are profoundly affected by the surroundings which they inhabit. Environmental psychologists have produced numerous credible theories describing optimal human environments, based on the concept of congruence or “fit” (1, 2). Lack of person/environment fit can lead to stress-related illness and lack of psychosocial well-being (3). Conversely, appropriately designed environments can promote wellness (4) or “salutogenesis” (5). Increasingly, research in the area of Evidence-Based Design, largely concentrated in the area of healthcare architecture, has tended to bear out these theories (6). Patients and long-term care residents, because of injury, illness or physical/ cognitive impairment, are less likely to be able to intervene to modify their immediate environment, unless this is designed specifically to facilitate their particular needs. In the context of care settings, detailed design of personal space therefore takes on enormous significance. MyRoom conceptualises a personalisable room, utilising sensoring and networked computing to enable the environment to respond directly and continuously to the occupant. Bio-signals collected and relayed to the system will actuate application(s) intended to positively influence user well-being. Drawing on the evidence base in relation to therapeutic design interventions (7), real-time changes in ambient lighting, colour, image, etc. respond continuously to the user’s physiological state, optimising congruence. Based on research evidence, consideration is also given to development of an application which uses natural images (8). It is envisaged that actuation will require machine-learning based on interpretation of data gathered by sensors; sensoring arrangements may vary depending on context and end-user. Such interventions aim to reduce inappropriate stress/ provide stimulation, supporting both instrumental and cognitive tasks.

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Esta investigação objetiva rastrear cognitivamente as pessoas idosas que se encontram sob resposta social, Centro de Dia e Lar de Idosos, no concelho de Miranda do Corvo e utiliza como instrumentos de rastreio o Mini Mental State Examination (MMSE) e o Montreal Cognitive Assessment (MoCA). Concomitantemente esta investigação propõe-se relacionar três itens do domínio da linguagem, propostos por nós, com as habilitações. A população que frequenta as instituições investigadas, 224 pessoas com idades 65 anos, apresenta as seguintes características sociodemográficas: 179 mulheres (79,9%), média de idades de 83,76 anos ( = ±7,29) sendo que 93 (41,5%) não possuem qualquer grau de escolaridade. A avaliação efetuada, durante o período de 19 de Dezembro de 2011 a 7 de Maio de 2012, evidencia que as pessoas que frequentam/residem estas/nestas respostas sociais apresentam elevados níveis de défice cognitivo quando comparadas com a população inquirida no “Estudo do Perfil do Envelhecimento da População Portuguesa” (2010). A diferença mostrou ser estatisticamente significativa independentemente de se utilizarem as referências para cortes etários de 65, de 65-74 ou de 75 anos de idade. Segundo os resultados obtidos através da administração do MMSE verificamos que dos 144 inquiridos 55 (38,2%) têm défice cognitivo. Se acrescentarmos a estes inquiridos os restantes utentes/clientes com diagnóstico de demência reportado nos processos individuais e confirmado através de sintomatologia tanto por nós como pela equipa técnica dos equipamentos esta percentagem sobe para 135 pessoas, ou seja, 135 (60,3%) das pessoas nestas respostas sociais. Na avaliação efetuada através do MoCA verificamos que 140 (97,2%) dos idosos têm défice cognitivo. Se acrescentarmos a estes inquiridos os restantes utentes/clientes com diagnóstico de demência esta percentagem sobe para 220 pessoas, ou seja, 98,2% das pessoas nestas respostas sociais. Os resultados obtidos, independentemente da magnitude da diferença avaliativa nos dois instrumentos utilizados, facto que consideramos não ser alheio às características sociodemográficas da coorte geracional que frequenta este tipo de respostas, atestam a prevalência do défice cognitivo nas instituições que acolhem pessoas idosas. Assim, propomos que as respostas sociais implementem programas de estimulação cognitiva para a conservação e melhoria das capacidades cognitivas dos idosos. / This investigation aims to track cognitively older people who are under social response, Day Centre and Home for the Aged, in the municipality of Miranda do Corvo and used as screening tools for the Mini Mental State Examination (MMSE) and the Montreal Cognitive Assessment (MoCA). Concomitantly this research proposes three items relate domain language, proposed by us, with qualifications. The people who attend the institutions surveyed, 224 people aged ≥ 65 years, presents the following sociodemographic characteristics: 179 women (79.9%), mean age of 83.76 years (σ = ± 7.29) being 93 (41.5%) do not have any schooling. The assessment carried out during the period from 19 December 2011 to May 7 2012, shows that people who attend / they reside / these social responses show high levels of cognitive impairment when compared with the population surveyed in the "Study Profile Aging of the Population Portuguese "(2010). The difference proved to be statistically significant regardless of whether the reference to use of cuts age ≥ 65, ≥ 75 or 65-74 years old. According to the results obtained by administering the MMSE found that 55 of the 144 respondents (38.2%) had cognitive impairment. If we add to these the remaining respondents users / clients with dementia reported in individual cases and confirmed by symptoms both by us and by the technical team of equipment that percentage goes up to 135 persons, ie, 135 (60.3%) of people in these social responses. In the evaluation conducted by MoCA found that 140 (97.2%) of the elderly have cognitive impairment. If we add to these the remaining respondents users / clients diagnosed with dementia this percentage rises to 220 people, or 98.2% of the people in these social responses. The results, regardless of the magnitude of the difference in the two evaluative instruments used, that we consider not to be oblivious to the sociodemographic characteristics of the generational cohort that attends this type of answers, attest to the prevalence of cognitive impairment in institutions for elderly people. Thus, we propose that the answers implement social cognitive stimulation programs for the conservation and improvement of cognitive abilities of the elderly.

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O presente estudo teve como objectivo principal conhecer melhor aspectos relacionados com a sexualidade na 3ª idade. A escala utilizada foi construída por nós, tornando-se num elemento chave para esta pesquisa. A escala de atitudes face à sexualidade no idoso foi relacionada com algumas características sociodemográficas: género, idade, estado civil, escolaridade e religião. Da análise realizada ressaltam evidências de uma atitude conservadora face às questões da sexualidade na 3ª idade. Através de uma amostra de 120 idosos com idades compreendidas entre os 60 e os 97 anos de idade, constatámos que os homens e as mulheres distinguem-se significativamente no que respeita às atitudes face à sexualidade, exibindo os homens uma atitude global mais positiva e liberal (M = 25.82). Os resultados evidenciaram um efeito significativo da variável escolaridade sobre o nível cognitivo, revelando que quanto maior a escolaridade do idoso na nossa amostra, maior é o nível cognitivo. Relativamente ao estado civil, os casados revelaram uma atitude global mais positiva perante a sua sexualidade (M = 31.98) comparativamente aos viúvos (M = 27.26) e aos divorciados (M = 23.67). A religião apenas se mostrou associada com a escala de atitudes face ao cristianismo, evidenciando aqueles que são praticantes, uma atitude mais positiva em relação ao cristianismo. Na nossa amostra, também podémos constatar que quanto maior é o nível cognitivo, mais positiva é a atitude face à sexualidade. Com base nos pontos de corte do MMSE verificou-se que 75% dos idosos da nossa amostra não apresentava qualquer défice cognitivo. Comparados os grupos, sem e com défice cognitivo, constatou-se que o grupo de idosos sem défice cognitivo exibe uma atitude mais positiva face à sexualidade que o grupo com défice cognitivo. Pretendemos que de alguma forma este estudo contribua para dar a conhecer as atitudes dos idosos face à sua sexualidade bem como esperamos que os nossos resultados permitam uma reflexão sobre possíveis estratégias de intervenção no sentido de promover uma sexualidade bem vivida por esta faixa etária. / The present study aimed to better understand the main aspects related to sexuality in the 3rd age. The scale used was built by us, becoming a key element in this research. The scale of attitudes towards sexuality in the elderly was related to sociodemographic characteristics: gender, age, marital status, education and religion. From the analysis point out evidence of a conservative approach in relation to issues of sexuality in the 3rd age. Using a sample of 120 elderly aged 60 and 97 years old, found that men and women differ significantly with regard to attitudes towards sexuality, men showing a more positive overall attitude and liberal (M = 25.82). The results showed a significant effect on the education variable cognitive level, revealing that the higher the education of the elderly in our sample, the higher the cognitive level. With regard to marital status, married people showed a more positive overall attitude towards their sexuality (M = 31.98) compared to widowed (M = 27.26) and divorced (M = 23.67). The only religion was associated with the scale of attitudes to Christianity, showing those who are practitioners, a more positive attitude toward Christianity. In our sample, we can also see that the higher the cognitive level, the more positive attitude towards sexuality. Based on the MMSE cutoffs found that 75% of older people in our sample did not show any cognitive deficit. Comparing the groups with and without cognitive impairment, it was found that the group of elderly people without cognitive impairment display a more positive attitude towards sexuality that the group with cognitive impairment. We intend that somehow this study contributes to publicize the attitudes of the elderly compared to their sexuality and we expect our results allow a discussion on possible intervention strategies to promote a sexuality lived well by this age group.

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Parece existir uma associação entre solidão e uma pobre qualidade subjetiva do sono. Em reforço desta ideia, alguns estudos mostraram que os sentimentos de solidão se associam a uma menor satisfação do sono, mesmo que a sua duração não esteja diminuída. Outros mostraram que a solidão se associa a sintomas depressivos. Sabe-se que na institucionalização são frequentes os problemas de sono, depressão e solidão. No entanto, falta saber o que se passa nas respostas sociais portuguesas. Assim foram os nossos principais objetivos descrever a qualidade subjetiva do sono e analisar a intensidade dos sintomas depressivos e dos sintomas de solidão em idosos institucionalizados, comparar com uma subamostra de idosos não institucionalizados e analisar a relação entre estas variáveis nas duas subamostras. Cento e quarenta idosos, com 70 institucionalizados e 70 não institucionalizados foram emparelhados por idade, sexo, escolaridade, estado civil e sem défice cognitivo. A média de idades foi de 76,58 (DP = 6,10), sendo 104 mulheres e 36 homens. Como instrumentos para a análise utilizámos um Questionário Sociodemográfico, o Questionário sobre o Sono na Terceira Idade, o Inventário de Depressão Geriátrica e a Escala de Solidão da Universidade da Califórnia, Los Angeles. Verificou-se que os idosos institucionalizados apresentavam mais sentimentos de solidão do que os não institucionalizados. Contudo, não se verificaram diferenças entre as duas subamostras em relação aos sintomas depressivos e à qualidade subjetiva do sono. Através de uma análise correlacional verificou-se nas duas subamostras que quanto pior a qualidade subjetiva do sono mais sintomas depressivos se observavam e quanto mais sintomas depressivos, mais sentimentos de solidão. Concluímos que não houve diferenças na qualidade subjetiva do sono pelo tipo de resposta social ainda que haja mais sintomas depressivos e sintomas de solidão nos idosos institucionalizados. Não encontrámos também relação entre o sono e a solidão nos idosos institucionalizados. / There seems to be an association between loneliness and poor subjective sleep quality. In support of this idea, some studies have shown that feelings of loneliness are associated with less satisfaction sleep, even if your life is not diminished. Others have shown that loneliness is associated with depressive symptoms. It is known that in the institutionalization are frequent problems with sleeping, depression and loneliness. However, lack know what is happening in the Portuguese social responses. So were our main objectives describe the subjective quality of sleep and analyze the intensity of depressive symptoms and loneliness symptoms in institutionalized elderly, compared with a non-institutionalized elderly subsample and analyze the relationship between these variables in both subsamples. One hundred and forty older adults, with 70 institutionalized and 70 non-institutionalized were matched by age, sex, education, marital status and without cognitive impairment. The average age was 76.58 (SD = 6.10), including 104 women and 36 men. As tools for the analysis we used a sociodemographic questionnaire, the Questionnaire About Sleep in the Older Adults, Geriatric Depression Inventory and the Loneliness Scale of the University of California, Los Angeles. It was found that the institutionalized older adults had more feelings of loneliness than noninstitutionalized. However, there were no differences between the two subsamples in relation to depressive symptoms and subjective sleep quality. Through a correlational analysis it was found in the two subsamples that the worse the subjective sleep quality more depressive symptoms were observed and the more depressive symptoms, more feelings of loneliness. We concluded that there no differences in subjective sleep quality by the type of social response even though there are more depressive symptoms and symptoms of loneliness in the elderly. Also we did not find relationship between sleep and loneliness in the elderly.

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RESUMO Objetivos: A presente investigação teve como principais objetivos descrever a qualidade subjetiva do sono e as perturbações do sono e analisar a intensidade dos sintomas depressivos e dos sentimentos de solidão em idosos institucionalizados; comparar estes dados com um grupo de idosos não institucionalizados e analisar a relação entre estas variáveis nos dois grupos. Métodos: Este estudo insere-se no Projeto Trajetórias do Envelhecimento de Idosos em Resposta Social de onde foi retirada uma amostra de cento e quarenta idosos sem défice cognitivo, com 70 institucionalizados e 70 não institucionalizados emparelhados por idade, sexo, escolaridade e estado civil. A média de idades foi de 76,58 (DP = 6,10), incluindo 104 mulheres e 36 homens. Como instrumentos foram utilizados um Questionário Sociodemográfico, o Questionário sobre o Sono na Terceira Idade, a Escala Geriátrica de depressão e a Escala de Solidão da Universidade da Califórnia, Los Angeles. Resultados: Verificou-se que os idosos institucionalizados apresentavam mais sentimentos de solidão do que os não institucionalizados. Contudo, não se verificaram diferenças entre os dois grupos em relação aos sintomas depressivos, qualidade subjetiva do sono ou perturbações do sono, com algumas exceções: os idosos residentes na comunidade mostraram ter a perceção de demorar mais tempo a adormecer, de acordar mais cedo e de ter mais pesadelos. Através de uma análise correlacional verificou-se, na amostra global, que quanto pior a qualidade subjetiva do sono mais sintomas depressivos se observavam e quanto mais sintomas depressivos, mais sentimentos de solidão, não havendo, contudo, relação entre o sono e a solidão. Conclusões: Concluímos que a situação de institucionalização se acompanha de mais sentimentos de solidão, mas não de sintomas depressivos ou de pior qualidade de sono. Por esse motivo, sugere-se que se desenvolvam programas de intervenção dirigidos à solidão em idosos institucionalizados. ABSTRACT Aims: The main objectives of this investigation were to describe the subjective quality of sleep and sleep disorders and analyze the intensity of depressive and loneliness symptoms in institutionalized elderly people; compare these data against a non-institutionalized elderly people subsample and analyze the relationship between these variables in both subsamples. Method: This study is part of Trajectories of Elderly Aging in Social Response Project from which a sample of one hundred and forty elderly people with no cognitive impairment was taken, with 70 institutionalized and 70 non-institutionalized matched by age, sex, education, and marital status. The average age was 76.58 (SD = 6.10), including 104 women and 36 men. The tools used for this analysis were a sociodemographic questionnaire, the Questionnaire About Sleep in the Older Adults, Geriatric Depression Scale, and the Loneliness Scale of the University of California, Los Angeles. Results: The study confirmed that institutionalized elderly people had more feelings of loneliness than those non-institutionalized. However, there were no differences between the two subsamples regarding depressive symptoms and subjective sleep quality or sleep disturbances, with some exceptions: Elderly people living in the community showed to have the perception of taking more time to fall asleep, waking up earlier, and having more nightmares. Through a correlational analysis it was found, in both subsamples, that the worse the subjective sleep quality the more depressive symptoms were observed; and the more depressive symptoms, the more feelings of loneliness, despite of not existing a relation between sleep and loneliness. Conclusions: We concluded that institutionalization is linked to more feelings of loneliness but not to depressive symptoms nor to worse quality of sleep. For this reason, it is suggested that intervention programs are developed with a focus on elderly institutionalized populations.

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Purpose To examine patient-reported outcome (PRO) in a selected group of Swedish patients about to receive anti-vascular endothelial growth factor (VEGF) treatment for diabetic macular edema (DME). Material and methods In this cross-sectional study, 59 patients with diabetes mellitus, who regularly visited the outpatient eye-clinics, were included. Sociodemographic and clinical data were collected and the patients completed PRO measures before starting anti-VEGF treatment. PRO measures assessed eye-specific outcomes (NEI-VFQ-25) and generic health-related quality of life (SF-36). Results The participants consisted of 30 men and 29 women (mean age, 68.5 years); 54 (92 %) patients had type 2 diabetes; Five (9%) patients had moderate or severe visual impairment; 28 (47 %) were classified as having mild visual impairment. Some of the patients reported overall problems in their daily lives, such as with social relationships, as well as problems with impaired sight as a result of reduced distance vision. Conclusions Further studies are needed to investigate PRO factors related to low perceived general health in this patient population. It is important to increase our understanding of such underlying mechanisms to promote improvements in the quality of patient care.

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RESUMO Objetivos. O défice mnésico é uma das alterações cognitivas que mais afeta as pessoas idosas. A idade é considerada um dos fatores de relevo nas alterações de memória, inclusivamente pelas próprias pessoas idosas. A investigação tem mostrado que existem outros fatores além da idade que afetam a memória das pessoas idosas. Contudo, fica por esclarecer qual o real papel da idade sobre a memória quando é controlada a influência de outras variáveis. Assim, o presente estudo pretende analisar o impacto da idade no funcionamento mnésico de pessoas idosas e verificar se, ao controlar o papel de outras variáveis (sexo, escolaridade, profissão, situação civil, situação residencial e situação clínica), esse potencial impacto se mantém. Métodos. A amostra global foi constituída por 1126 participantes (283 homens e 843 mulheres; 226 residentes na comunidade e 900 em resposta social dirigida à população idosa) com idades compreendidas entre os 60 e os 100 anos. A avaliação foi realizada com recurso aos itens do Mini-Mental State Examination (memória de trabalho), o fator do Montreal Cognitive Assessment (memória declarativa verbal) e Figura Complexa de ReyOsterrieth (memória visuoespacial). Resultados. Globalmente, a idade, escolaridade, profissão, situação civil, residencial e clínica influenciaram a memória de forma diferenciada consoante o tipo de memória. As análises de regressão hierárquica mostraram que a idade é um fator preditivo em todos os tipos de memória. Emergiram ainda outros fatores preditivos com coeficientes de regressão superiores à idade conforme o tipo de memória (exceto na memória de trabalho). Conclusões. A idade, a escolaridade e a profissão influenciam a memória, assim como os fatores que potencialmente estimulam cognitiva e socialmente (como ter um companheiro e residir na comunidade). Os resultados apontam para a importância de intervir em pessoas em respostas sociais, mais idosas, sem companheiro, com baixa escolaridade e profissão manual. ABSTRACT Goals. Memory impairment is one of the types of cognitive impairment that most affects the elderly. Age is considered one of the major factors in memory impairment, including by the elderly themselves. Research has shown that there are other factors affecting memory of elderly persons. It remains, however, unclear what is the real impact of age in memory when controlling the influence of other variables. Thus, this study aims to analyze the impact of age on memory functioning of elderly persons and check if the potential impact remains when controlling the role of other variables (sex, education, profession, marital status, residential status, and clinical situation). Methods. The global sample comprised 1126 subjects (283 men and 843 women, 226 residents in the community and 900 institutionalized elderly) aged from 60 to 100 years. The assessment included items from the MiniMental State Examination (working memory), the Montreal Cognitive Assessment factor (verbal declarative memory), and Rey-Osterrieth Complex Figure (visuospatial memory). Results. Overall, age, education, profession, marital, residential, and clinical condition have differently influenced memory, depending on the type of memory. The hierarchical regression analysis showed that age is a predictive factor in all types of memory. However, other predictors have emerged with higher regression coefficients compared to age, according to the type of memory (except in working memory). Conclusions. Age, education and profession influence memory, as well as factors that potentially stimulate cognitively and socially (like having a partner and living in the community). The results indicate the importance of intervening, especially among institutionalized elderly, older, unmarried, with low education, and manual profession.

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Alzheimer’s disease (AD) is the most prevalent age-related neurodegenerative disease that leads to cognitive impairment and dementia. The major defined pathological hallmark of AD is the accumulation of amyloid beta (Aβ), a neurotoxic peptide, derived from beta and gamma-secretase cleavage of the amyloid precursor protein (APP). It has been described that cellular prion protein (PrPC) plays a role in the pathogenesis of Alzheimer disease. Although, the role of PrPC is still unclear, previous studies showed contradictious results. To elucidate this issue, the main objective of the present study is to investigate the influence of a knockout of the PRNP gene in 5XFAD mice, 5xFAD mice exhibited 5 mutations related to familial Alzheimer disease. These mice show an Aβ1-42 accumulation and an increased neuronal loss during aging. To create a bi-transgenic 5xFAD mice were crossed with Prnp0/0 Zurich 1 mice (prion protein knockout mice). We subjected two transgenic mice (5xFAD and Prnp0/05xFAD) at different ages (3, 9 and 12 months of age) to a battery of task to evaluate cognitive and motoric deficits and a biochemical analysis (ELISA, western blot and immunohistochemistry) to investigate the regulation and potential involvement of downstream signaling proteins in the Aβ induced toxicity process dependent of the PrPC concentration. The study revealed that the deficits induced by Aβ mediated toxicity appeared earlier in 5xFAD mice (9 months of age) than in Prnp0/05xFAD (12 months of age). Investigating the amount of amyloid beta in 5xFAD mice we observed a PrPC dependent regulation in 9 month-old animals of Aβ1−40 but not of the toxic form Aβ1−42. We did not found in Prnp0/05xFAD mice the up-regulation of P-Fyn, Fyn or Cav-1 as we found in 5xFAD mice. This suggests an important role of PrPC in Alzheimer’s disease as a promoter of toxic effect of Aβ oligomers. Our results may suggest the loss of PrPC delays the toxicity of amyloid beta. In conclusion, our data support a role of PrPC as a mediator of Aβ toxicity in AD by promoting early onset of disease.

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Introdução: as quedas são um importante problema na saúde nos idosos, apresentando os idosos institucionalizados um risco específico, determinado pela mudança de ambiente, diminuição da atividade física e alterações na independência funcional. Objetivo: estimar a prevalência e avaliar o risco de quedas nos idosos institucionalizados na ULDM – Sta Maria Maior de Miranda do Douro no período compreendido entre 02/12/2008 e 31/08/2014. Conhecer quais as estratégias de prevenção implementadas para evitar a recorrência de quedas nos idosos com histórico de quedas. Metodologia: Estudo descritivo e analítico de caráter retrospetivo, sobre uma amostra constituída por utentes com idade igual ou superior a 65 anos, internados numa Unidade de Longa Duração e Manutenção, no período compreendido entre 02/12/2008 e 31/08/2014 (N=158). Resultados: A prevalência de quedas foi de 14%. As quedas tiveram como principais fatores de risco a idade avançada, a presença de doenças crónicas, a mobilidade reduzida, défice cognitivo e polimedicação. O quarto e o WC foram os espaços físicos onde ocorreram com mais frequência. As principais causas foram, por esta ordem, a perda de apoio, episódio de desorientação/agitação e a perda de consciência. A maior parte das quedas não tiveram consequências físicas para o idoso ou limitaram-se a lesões traumáticas. As medidas de prevenção mais frequentemente aplicadas foram as medidas de apoio e a contenção física. Conclusão: nos resultados obtidos verifica-se uma prevalência de quedas muito superior quando comparada com outros estudos nesta área. Os dados apontam à necessidade de implementação de políticas institucionais de prevenção de quedas.

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Alzheimer’s disease is the most common cause of dementia which causes a progressive and irreversible impairment of several cognitive functions. The aging population has been increasing significantly in recent decades and this disease affects mainly the elderly. Its diagnostic accuracy is relatively low and there is not a biomarker able to detect AD without invasive tests. Despite the progress in better understanding the disease there remains no prospect of cure at least in the near future. The electroencephalogram (EEG) test is a widely available technology in clinical settings. It may help diagnosis of brain disorders, once it can be used in patients who have cognitive impairment involving a general decrease in overall brain function or in patients with a located deficit. This study is a new approach to improve the scalp localization and the detection of brain anomalies (EEG temporal events) sources associated with AD by using the EEG.

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Background and aims: Head injury (HI) is a cause of cognitive impairment within the homeless population (Hwang et al, 2008). One study reported that over a 30-year period, the prevalence of hospitalised HI was 5.4 times higher in the homeless than in the general population (McMillan et al, 2015). This study explores the perceptions of homeless adults who have sustained a HI and their views regarding the relevance of HI to their homeless status. Methods: Participants were seven homeless adults with a moderate or severe HI. They were asked to talk about their journey to homelessness and in particular, to reflect on any perceived links between HI and their homeless status. The data were analysed using Interpretative Phenomenological Analysis (IPA). Results and conclusions: Emerging themes included: impairment following HI; substance misuse, feeling let down by services and difficult relationships with family. Evidence for the role of HI in precipitating and maintaining homelessness was found. Despite this, co-morbid difficulties complicate the picture. Four out of seven participants viewed substance misuse as their primary difficulty. This illustrates the need for in-depth assessment within this population in order to ensure that difficulties are fully understood and that the correct supports/ interventions are offered.

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Background The prevalence of geriatric syndromes (falls, immobility, intellectual or memory impairment, and incontinence) is unknown in many resource-poor countries. With an aging population such knowledge is essential to develop national policies on the health and social needs of older people. The aim of this study was to provide a preliminary survey to explore the prevalence of falls and other geriatric syndromes and their association with known risk factors in people aged > 60 years in urban Blantyre, Malawi. Methods This was a cross-sectional, community survey of adults aged > 60 years. Subjects were recruited at home or in the waiting areas of chronic care clinics. They were interviewed to complete a questionnaire on ageassociated syndromes and comorbid problems. The Abbreviated Mental Test (AMT) and Timed Up and Go (TUG) tests were carried out. Results Ninety-eight subjects were studied; 41% reported falling in the past 12 months, 33% of whom (13% of all subjects) were recurrent fallers. Twenty-five percent reported urine incontinence, 66% self-reported memory difficulties, and 11% had an AMT score < 7. A history of falling was significantly associated with urine incontinence (p=0.01), selfreported memory problems (p=0.004) and AMT score < 7 (p=0.02). Conclusions Geriatric syndromes, including falls, appear to be prevalent in older people in Blantyre, Malawi. Falling is associated with cognitive impairment and urinary incontinence. There is an urgent need for more understanding of geriatric problems in this setting to develop national policies on health and social needs of older people. It is likely that many of the contributory factors to falls would be amenable to multifactorial interventions similar to those found to be effective in developed countries.

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Objective: To assess potentially inappropriate prescribing (PIP) using Beers (2012 version) and STOPP (2008 version) criteria in polypharmacy, community-dwelling, older patients. Methods: From the information collected in the invoicing data of the prescriptions and the electronic medical records, a sample was selected of 223 ≥ 65-year-old patients who were taking simultaneously 10 or more drugs per day. Beers and STOPP criteria were separately applied, and the results obtained with the two methods were compared. Results: A total of 141 (63.2%) patients presented at least one Beers criterion. The two most frequently observed Beers criteria independent of diagnosis were the use of benzodiazepines and the use of non-COX-2-selective non-steroidal anti-inflammatory drugs. With regard to Beers criteria considering diagnosis, the most frequent were the use of anticholinergic drugs in patients with lower urinary tract symptoms or benign prostatic hyperplasia, and the use of benzodiazepines, antipsychotics, Zolpidem or H2-antihistamines, in patients with dementia or cognitive impairment. A total of 165 (73.9%) patients had at least one PIP according to the STOPP criteria. Duplicate drug classes and long-term use of long-acting benzodiazepines were the two most frequent STOPP criteria. Discussion: Our study identified a high frequency of PIP in poly-medicated community-dwelling older patients. Simultaneous application of Beers and STOPP criteria represents a useful tool to improve prescribing in this population group.

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El 6.5% de la población ecuatoriana son adultos mayores, falleciendo alrededor de 34.000 cada año. Su bienestar constituye una preocupación política y social, pero sus derechos muchas veces son vulnerados por una sociedad que vive su cotidianidad en lucha contra el más fuerte y olvida extender la mano a los protagonistas del pasado, quienes muestran un impacto negativo en su salud integral. METODOLOGÍA: Estudio descriptivo en 40 adultos mayores de la comunidad de Maluay (95,2%) en quienes se valoró la salud integral a través del uso de formularios del MSP. También, se aplicaron técnicas documentales y de observación directa para recolección de datos. RESULTADOS La mayoría son mujeres entre 65 y 74 años, media de 69.5 años, analfabetos/as (93%), sin actividad o dedicados al trabajo de campo y no cuentan con agua potable. Sus condiciones se ven afectadas por enfermedades crónicas degenerativas que les confiere cierto grado de discapacidad. Presentan riesgo de desnutrición (73%), déficit cognitivo (65%), casi la mitad con cierta dificultad en el equilibrio y la marcha. Aunque sean independientes en las actividades básicas de la vida diaria, necesitan cierta ayuda en actividades instrumentales. Socialmente son aceptados (78%). DISCUSIÓN La calidad de vida de los adultos mayores, especialmente en sectores rurales no es apropiada pese al respaldo de políticas públicas. El conocimiento de los factores de riesgo y sus necesidades para elaborar estrategias de prevención y promoción con un enfoque holístico debe ser la prioridad en la Salud Pública, pues atravesamos una transición que se dirige a los riesgos emergentes asociados con la industrialización, la urbanización y el envejecimiento poblacional

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Se entendemos o Acidente vascular cerebral como um acontecimento incapacitante da vida dos pacientes, poderemos compreender as alterações comportamentais e emocionas que este provoca. No entanto, poucos estudos têm sido realizados acerca desta temática, tendo assim este estudo como objetivo verificar se existe uma associação clara entre a ansiedade e um determinado tipo de AVC. Aplicou-se a escala de Montereal, o State-Trait Anxiety lnventory e o Inventario Neuropsiquiátrico numa amostra constituída por pacientes que tenham sofrido AVC no período de três meses a um ano, e num grupo controlo. Os resultados mostram que não existem diferenças significativas no que respeita à ansiedade nos pacientes com AVC anterior. Conclui-se que não existe um aumento de ansiedade, mas que os défices visuo-espaciais e atencionais são mais significativos no AVC anterior. / ABSTRACT: lf we recognize Stroke as an event that can incapacitate the patients' life, we can comprehend the behaviour and emotional changes that this provokes. One of the psychiatric symptoms usually associated to Stroke is anxiety. However, few studies have been made concerning this matter, being the purpose of this study to verify if a clear association exists between anxiety and a certain type of Stroke. The Montereal Cognitiva Assessment, State-Trait Anxiety lnventory, and Neuropsychiatric lnventory were applied in a sample consisting of patients that have suffered Stroke in the period of three months to one year, and in a control group. The results show no significant differences in what regards to anxiety in patients with previous Stroke. We conclude that there is no increase in anxiety after stroke, but cognitive deficits in visual-spatial and attentional are most significant in subjects with previous stroke.