Directors Meeting November 28, 1896 and By-Law No. 14 & 15

The meeting included an election of officers which resulted as follows: John Reid, President; Geo Barnes, Vice President; Geo. Barnes, Man-Director; J. Evans, Secretary. There are also two more by-laws (14 and 15) signed by both G. Barnes and J. Evans.

Annual Meeting September 1, 1898 and By-Law no.16

The meeting includes by-law no. 16 which makes payable a "dividend on the capital stock of the Ontario Grape Growing and Wine Manufacturing Co. for the year ending May 31st 1898".

Meeting Minutes July 7th, 1972

The first "business arising out of the minutes" is a protest made by Mr. W.R. Barnes concerning action taken at a previous meeting by the Directors. In the meeting in February, he had been replaced as Vice-President after 20 years in the role and 38 years as a Director. His record of attendance was called into question and would be discussed and shown at the next meeting. The second issue discussed is the "proposal with respect to purchasing the assets of the Corporation". A letter was received from F.L. Laundry Real Estate Limited with interest from a Central European client in "acquiring the assets of the Corporation, and indicating that if the circumstances warranted, a figure of 3.5 millions would not be beyond their capabilities". The offer would be explored by the solicitor. The next agenda item discusses was the Sault Ste. Marie store. Another issue discussed was the "Withdrawal from Valley Rouge Wines Limited".

Meeting Minutes September 11, 1972

The meeting begins with an amendment to a banking by-law from February 1966. The amendment would allow Miss D.M. Harwood to sign cheques. The list of business is as follows: Valley Rouge Wines Limited Final Release, G & A Holdings Incorporated offer to purchase 40 Acres, F.L. Laundry Real Estate, Purchase of Shares of Bessy Barnes Barkley Gay, Date of Annual Meeting, Retirement of Miss Goffin, Salary of Vice-President and Managing Director, Term Insurance on Vice-President and General Manager, Appointment of Vice-President, Negotiation with Dr. Peller.

The Arabidopsis NPR1 Protein Is a Receptor for the Plant Defense Hormone Salicylic Acid

Systemic Acquired Resistance (SAR) is a type of plant systemic resistance occurring against a broad spectrum of pathogens. It can be activated in response to pathogen infection in the model plant Arabidopsis thaliana and many agriculturally important crops. Upon SAR activation, the infected plant undergoes transcriptional reprogramming, marked by the induction of a battery of defense genes, including Pathogenesis-related (PR) genes. Activation of the PR-1 gene serves as a molecular marker for the deployment of SAR. The accumulation of a defense hormone, salicylic acid (SA) is crucial for the infected plant to mount SAR. Increased cellular levels of SA lead to the downstream activation of the PR-1 gene, triggered by the combined action of the Non-expressor of Pathogenesis-related Gene 1 (NPR1) protein and the TGA II-clade transcription factor (namely TGA2). Despite the importance of SA, its receptor has remained elusive for decades. In this study, we demonstrated that in Arabidopsis the NPR1 protein is a receptor for SA. SA physically binds to the C-terminal transactivation domain of NPR1. The two cysteines (Cys521 and Cys529), which are important for NPR1’s coactivator function, within this transactivation domain are critical for the binding of SA to NPR1. The interaction between SA and NPR1 requires a transition metal, copper, as a cofactor. Our results also suggested a conformational change in NPR1 upon SA binding, releasing the C-terminal transactivation domain from the N-terminal autoinhibitory BTB/POZ domain. These results advance our understanding of the plant immune function, specifically related to the molecular mechanisms underlying SAR. The discovery of NPR1 as a SA receptor enables future chemical screening for small molecules that activate plant immune responses through their interaction with NPR1 or NPR1-like proteins in commercially important plants. This will help in identifying the next generation of non-biocidal pesticides.

Modeling short-range ballistic missile defense and Israel's Iron Dome system

This paper develops a model of short-range ballistic missile defense and uses it to study the performance of Israel’s Iron Dome system. The deterministic base model allows for inaccurate missiles, unsuccessful interceptions, and civil defense. Model enhancements consider the trade-offs in attacking the interception system, the difficulties faced by militants in assembling large salvos, and the effects of imperfect missile classification by the defender. A stochastic model is also developed. Analysis shows that system performance can be highly sensitive to the missile salvo size, and that systems with higher interception rates are more “fragile” when overloaded. The model is calibrated using publically available data about Iron Dome’s use during Operation Pillar of Defense in November 2012. If the systems performed as claimed, they saved Israel an estimated 1778 casualties and $80 million in property damage, and thereby made preemptive strikes on Gaza about 8 times less valuable to Israel. Gaza militants could have inflicted far more damage by grouping their rockets into large salvos, but this may have been difficult given Israel’s suppression efforts. Counter-battery fire by the militants is unlikely to be worthwhile unless they can obtain much more accurate missiles.

Clipping from a Town Council meeting at which estimates of the costs of Railway Line no. 1 and Line no. 2 were submitted by the office of Port Dalhousie and Thorold Railway

Clipping from a Town Council meeting at which estimates of the costs of Railway Line no. 1 and Line no. 2 were submitted by the office of Port Dalhousie and Thorold Railway. The estimate was submitted by S.D. Woodruff and George Rykert, president. There is also a disclaimer in which Calvin Phelps claims to have resigned as director of the Port Dalhousie and Thorold Railway when he discovered that the company had no intention to adhere to the original plan for building and running the road, Aug. 1854.

Minutes of a meeting of the members of the Long Point Company

Minutes of a meeting of the members of the Long Point Company (1 page, printed). This has the names J.I. Mackenzie, secretary and Horatio Hathaway, chairman on the bottom of the page, Oct. 28, 1880.

Long Point Company annual meeting

Long Point Company annual meeting (1 page, printed). John I. Mackenzie, secretary-treasurer is listed on the bottom of the page, June 7, 1881.

Meeting of the special committee on new arrangements

Meeting of the special committee on new arrangements (3 copies of 1 page, printed). This has John I. Mackenzie listed on the bottom of the page. Copies 2 and 3 are torn at the bottom. This affects the text slightly, Aug. 23, 1881.

Annual consultation meeting of the Long Point Company

Annual consultation meeting of the Long Point Company (1 page, printed). The names Jos. A. Woodruff, chairman and J.I. Mackenzie, secretary are at the bottom of the page, Oct. 27, 1881.

Meeting of shareholders, yeas and nays

Meeting of shareholders, yeas and nays (1 page, printed), Nov. 18, 1881.

Annual meeting of the Long Point Company attached to a copy of the May 31, 1882 balance sheet

Annual meeting of the Long Point Company (1 page, printed) attached to a copy of the May 31, 1882 balance sheet (1 page, printed). The meeting has the name J.I. Mackenzie, assistant secretary-treasurer on the bottom and the balance sheet has the names J.I. Mackenzie, secretary treasurer and Geo. H. Gillespie, auditor on the bottom of the page, June 6, 1882.

Annual consultation meeting of the Long Point Company

Annual consultation meeting of the Long Point Company (1 page, printed). The name J.I. Mackenzie, secretary is at the bottom of the page, Oct. 26, 1882.

Annual meeting of the Long Point Company

Annual meeting of the Long Point Company (1 page, printed). The name J.I. Mackenzie, secretary is at the bottom of the page, June 5, 1883.