The answer of Mr. Sullivan, to the letter and mis-statements of the Hon. Cadwallader D. Colden, in his "Brief exposition" of himself as the advocate of monopoly. The unconstitutionality or limitation of the monopoly demonstrated. The bad policy and injurious effects of it on the community exposed. The legality of an extension of the term of time of a patent when for the good of a state; and the just views and claims of patentees in steam navigation fully explained.

Pages 29-34 contain "Mr. Duer's opinion on the claim of Mr. Sullivan as a patentee, to navigate with steam boats, the waters of the state of New-York."

Camp-fire and cotton-field: southern adventure in time of war. Life with the Union armies, and residence on a Louisiana plantation.

Mode of access: Internet.

History of the town of Hampton Falls, New Hampshire from the time of the first settlement within its borders.

Title varies: Vol. II has title History of Hampton Falls, N.H.

Collections concerning the church or congregation of Protestant Separatists formed at Scrooby in north Nottinghamshire, in the time of King James I : the founders of New-Plymouth, the parent-colony of New-England /

"This volume is in one sense a second edition of a tract which was printed in 1849, entitled 'Collections concerning the early history of the founders of a New Plymouth, the first colonists of New England'"--P. vii.

Civil and ecclesiastical history of the city of Exeter and its environs, from the time of the Romans to the year 1806.

Mode of access: Internet.

Thirty-one years on the plains and in the mountains, or, The last voice from the plains : an authentic record of a life time of hunting, trapping, scouting and Indian fighting in the far West /

Mode of access: Internet.

Inter arma; being essays written in time of war,

Reprinted from the Edinburgh review.

Nova Solyma, the ideal city; or, Jerusalem regained; an anonymous romance written in the time of Charles I., now first drawn from obscurity, and attributed to the illustrious John Milton.

Ascribed to Samuel Gott by S. K. Jones (in the Library, 3d ser., no. 3, v. 1, July 1910)

A complete history of the Marquis de Lafayette, major general in the army of the United States of America, in the war of the revolution : embracing an account of his late tour thorough the United States to the time of his departure, September, 1825 /

Mode of access: Internet.

Journal of Daniel Coker, : a descendant of Africa, from the time of leaving New York, in the ship Elizabeth, Capt. Sebor, on a voyage for Sherbro, in Africa, in company with three agents, and about ninety persons of colour. : The Rev. Samuel Bacon, John B. Bankson, Samuel S. Crozer. Agents. : With an appendix.

"Appendix to the Rev. D. Coker's Journal" (pages [41]-52) includes "Letter from Nathaniel Peck to his mother in Baltimore".

Sensory hypersensitivity occurs soon after whiplash injury and is associated with poor recovery

Hypersensitivity to a variety of sensory Stimuli is a feature of persistent whiplash associated disorders (WAD). However, little is known about sensory disturbances from the time Of injury until transition to either recovery or symptom persistence. Quantitative sensory testing (pressure and thermal pain thresholds, the brachial plexus provocation test), the sympathetic vasoconstrictor reflex and psychological distress (GHQ-28) were prospectively measured in 76 whiplash Subjects within 1 month of injury and then 2, 3 and 6 months post-injury. Subjects were classified at 6 months post-injury using scores on the Neck Disability Index: recovered (30). Sensory and sympathetic nervous system tests were also measured in 20 control subjects. All whiplash groups demonstrated local mechanical hyperalgesia in the cervica spine at 1 month post-injury. This hyperalgesia persisted in those with moderate/severe symptoms at 6 months but resolved by 2 months in those who had recovered or reported persistent mild symptoms. Only those with persistent moderate/severe symptoms at 6 months demonstrated generalised hypersensitivity to all sensory tests. These changes Occurred within 1 month of injury and remained Unchanged throughout the Study period. Whilst no significant group differences were evident for the sympathetic vasoconstrictor response, the moderate/severe group showed a tendency for diminished sympathetic reactivity. GHQ-28 scores of the moderate/severe group were higher than those of the other two groups. The differences in GHQ-28 did not impact on any of the sensory measures. These findings suggest that those with persistent moderate/severe symptoms at 6 months display, soon after injury, generalised hypersensitivity suggestive of changes in central pain processing mechanisms. This phenomenon did not Occur in those who recover or those with persistent mild symptoms. (C) 2003 International Association for the Study of Pain. Published by Elsevier Science B.V. All rights reserved.

Peptide quantification by matrix-assisted laser desorption ionisation time-of-flight mass spectrometry: Investigations of the cyclotide kalata B1 in biological fluids

A rapid method has been developed for the quantification of the prototypic cyclotide kalata B I in water and plasma utilizing matrix-assisted laser desorption ionisation time-of-flight (MALDI-TOF) mass spectrometry. The unusual structure of the cyclotides means that they do not ionise as readily as linear peptides and as a result of their low ionisation efficiency, traditional LC/MS analyses were not able to reach the levels of detection required for the quantification of cyclotides in plasma for pharmacokinetic studies. MALDI-TOF-MS analysis showed linearity (R-2 > 0.99) in the concentration range 0.05-10 mu g/mL with a limit of detection of 0.05 mu g/mL (9 fmol) in plasma. This paper highlights the applicability of MALDI-TOF mass spectrometry for the rapid and sensitive quantification of peptides in biological samples without the need for extensive extraction procedures. (c) 2005 Elsevier B.V. All rights reserved.

Morningness-eveningness orientation, optimal time-of-day and attitude change: Evidence for the systematic processing of a persuasive communication

This study investigates the effects of morningness-eveningness orientation and time-of-day on persuasion. In an attitude change paradigm, 120 female participants read a persuasive message that consisted of six counter-attitudinal arguments (anti-voluntary euthanasia) either in the morning (8:30 a.m.) or in the evening (7:00 p.m.). Attitude change was assessed by measuring attitudes towards the target issue before and after exposure to the message. Message processing was assessed by thought-listing and message recall tasks. Self-reported mood and arousal were monitored throughout. Participants were classified into M- and E-types according to their scores on the Horne and Ostberg (1976) MEQ questionnaire. When tested at their respective optimal time-of-day (i.e., morning for M-types/evening for E-types), M- and E-types reported higher energetic arousal, greater agreement with the message, greater message-congruent thinking, and a propensity for superior message recall compared to M- and E-types tested at their nonoptimal time-of-day (i.e., evening for M-types/morning for E-types). The attitude change in those tested at their optimal time-of-day was mediated by the level of message-congruent thinking. Results are interpreted in terms of the Elaboration Likelihood Model of persuasion. (c) 2005 Elsevier Ltd. All rights reserved.