Engineering Study for Reducing Sign Vandalism Final Report Highway Research Advisory Board Projec HR 246, June 1992

Sign vandalism has traditionally been a vexing problem for Iowa counties. The extent of the cost and incidence of these acts have never been fully ascertained, but a 1990 survey indicated that they cost Iowa counties more than 1.5 million dollars annually. In 1990, the Iowa Legislature recognized the seriousness of the problem and strengthened the existing sign vandalism law by increasing the penalty for illegal possession of a traffic control device from a simple to a serious misdemeanor. However, the courts must be willing to prosecute vandals to the magnitude provided in the Iowa Code. An educational campaign begun in 1987 involving over 200 Iowa school districts to educate students on the seriousness of the problem evidently did not have the effect of dramatically reducing the overall cost of sign vandalism in Iowa. This study sought to define the scope of the problem and possibly offer some effective countermeasures to combat sign vandalism and theft in Iowa.

Les méthodes d'études de cas en psychothérapie: perspectives actuelles [Methods of psychotherapy case studies: current perspectives].

There is a renewal of interest among psychotherapy researchers and psychotherapists towards psychotherapy case studies. This article presents two paradigms that have greatly influenced this increasing interest in psychotherapy case studies : the pragmatic case study and the theory-building case study paradigm. The origins, developments and key-concepts of both paradigms are presented, as well as their methodological and ethical specificities. Examples of case studies, along with models developed, are cited. The differential influence of the post-modern schools on both paradigms are presented, as well as their contribution to the field of methods of psychotherapy case studies discussed and assessed in terms of relevance for the researcher and the psychotherapist.

Engineering tolerance into transplanted beta cell lines.

In this paper we explore the possibility of improving, by genetic engineering, the resistance of insulin-secreting cells to the metabolic and inflammatory stresses that are anticipated to limit their function and survival when encapsulated and transplanted in a type 1 diabetic environment. We show that transfer of the Bcl-2 antiapoptotic gene, and of genes specifically interfering with cytokine intracellular signaling pathways, greatly improves resistance of the cells to metabolic limitations and inflammatory stresses.

[Voyage en Italie : 1824-1830]. , [Vue présumée de la Punta Nera, port et] rue en pente à Porto Ferrajo : [deux vues perspectives, un plan d'ensemble] : [dessin] / h. L. [Henri Labrouste]

Référence bibliographique : Weigert, 106

[Voyage en Italie : 1825-1830]. , Fontaine sur la place de S. Spirito ; fontaine adossée à la prison : [deux vues perspectives, un petit plan] : [dessin] / h. L. [Henri Labrouste]

Référence bibliographique : Weigert, 153

[Voyage en Italie : 1824-1830]. , [Modèles de claustrats et de bâtiments dans une chartreuse] : [détails de huit claustras en briques, vues perspectives de deux petits bâtiments agrémentés de deux desdits modèles de claustras] : [dessin] / h. L. [Henri Labrouste]

Référence bibliographique : Weigert, 163

[Voyage en Italie : 1824-1830]. , Chiesa di S. Giacomo : [vues perspectives de la façade et de la nef] : [dessin] / h. L. [Henri Labrouste]

Référence bibliographique : Weigert, 37