Lehrbuch der zoologie, von F. S. Voigt.

v. 4

Revision of Brachystethus (Heteroptera, Pentatomidae, Edessinae)

Brachystethus Laporte, 1832 is revised. Brachystethus coxalis Breddin, 1904, B. cribrus (Fabricius, 1781), B. geniculatus (Fabricius, 1787), B. improvisus Breddin, 1905, B. rubromaculatus Dallas, 1851, B. signoreti Stål, 1872, B. tricolor Bolívar, 1879, B. vexillum Breddin, 1903 and B. vicinus Signoret, 1851 are redescribed based on morphological characters, with emphasis on genitalia of both sexes. A new species, B. schuhi, from Guyana, is described, and B. discolor (Walker, 1867), incertae sedis, is removed from the genus. Illustrations and a key for species of Brachystethus are provided.

Diversidade de Pentatomoidea (Hemiptera, Heteroptera) em três fragmentos de Mata Atlântica no sul de Santa Catarina

A composição e a variação sazonal da fauna de Pentatomoidea (Hemiptera) foi avaliada entre setembro de 2005 e agosto de 2006 em três fragmentos de Mata Atlântica na região sul de Santa Catarina (Brasil): Parque Ecológico José Milanese (Criciúma, 28º41'23''S, 49º25'55''W), Parque Ecológico de Maracajá (Maracajá, 28º52'51''S, 49º27'59''W) e Balneário Morro dos Conventos (Araranguá, 28º56'05''S, 49º21'47''W). Foram realizadas coletas mensais ao longo de trilhas nas três áreas, utilizando guarda-chuva entomológico e rede de varredura para amostrar nas bordas de mata. Para um esforço amostral de 108 horas foram coletados 595 indivíduos, distribuídos em 4 famílias, 29 gêneros e 49 espécies. Pentatomidae foi a família mais abundante (82,69%) seguida de Cydnidae (15,97%), Scutelleridae (0,84%) e Tessaratomidae (0,50%). Pentatomidae também apresentou a maior riqueza com 37 espécies. As espécies mais abundantes foram Mormidea notulifera Stål, 1860, Oebalus ypsilongriseus (De Geer, 1773), Arvelius albopunctatus (De Geer, 1773), Edessa subrastrata Bergroth, 1891, Galgupha schulzii (Fabricius, 1781) e Agroecus scabricornis (Herrich-Schäffer, 1844). O período de maior captura foi entre o final da primavera e início do outono, representando 71,76% do total coletado. O Parque do Maracajá apresentou abundância e riqueza sgnificativamente maiores do que as demais áreas. Este estudo representa o primeiro inventário da diversidade de Pentatomoidea em habitats naturais no estado de Santa Catarina.

The Zariski-Lefschetz principle for higher homotopy groups of nongeneric pencils

We prove a general Zariski-van Kampen-Lefschetz type theorem for higher homotopy groups of generic and nongeneric pencils on singular open complex spaces.

Elementa botanica :genera genuina, species naturales omnium vegetabilium detectorum eorumque characteres diagnosticos ac peculiares exhibentia, secundum systema omologicum seu naturale, evulgata ...

v. 1

Elementa botanica :genera genuina, species naturales omnium vegetabilium detectorum eorumque characteres diagnosticos ac peculiares exhibentia, secundum systema omologicum seu naturale, evulgata ...

v. 2

Elementa botanica :genera genuina, species naturales omnium vegetabilium detectorum eorumque characteres diagnosticos ac peculiares exhibentia, secundum systema omologicum seu naturale, evulgata ...

v. 3

Informe de la estancia realizada en la división de neurociencias de la facultad de ciencias experimentales del Centro Andaluz de Biología del Desarrollo. Universidad Pablo de Olavide. Sevilla.

Investigación producida a partir de una estancia en la Universidad Pablo de Olavide de Sevilla entre los meses de mayo a julio del 2005. Con el objetivo de investigar la influencia de los factores neurotróficos en la patofisiología de los trastornos de ansiedad, se realizó un protocolo experimental de electrofisiología in vivo para caracterizar la formación de LTP en el hipocampo de un modelo murino de sobrexpresión del gen NTRK3. Para ello se fabricaron electrodos que fueron implantados en el cerebro de ratones mediante cirugía estereotáxica. Posteriormente se experimentó la habituación, condicionamiento y extinción de un estímulo sonoro, de un grupo de 12 ratones transgénicos NTRK3 y de 12 ratones controles durante varias sesiones. El análisis de las respuestas condicionadas reveló un problema en el aprendizaje en los ratones TgNTRK3.

Safety and immunogenicity of the M72/AS01 candidate tuberculosis vaccine in HIV-infected adults on combination antiretroviral therapy: a phase I/II, randomized trial.

OBJECTIVE: Tuberculosis (TB) is highly prevalent among HIV-infected people, including those receiving combination antiretroviral therapy (cART), necessitating a well tolerated and efficacious TB vaccine for these populations. We evaluated the safety and immunogenicity of the candidate TB vaccine M72/AS01 in adults with well controlled HIV infection on cART. DESIGN: A randomized, observer-blind, controlled trial (NCT00707967). METHODS: HIV-infected adults on cART in Switzerland were randomized 3 : 1 : 1 to receive two doses, 1 month apart, of M72/AS01, AS01 or 0.9% physiological saline (N = 22, N = 8 and N = 7, respectively) and were followed up to 6 months postdose 2 (D210). Individuals with CD4⁺ cell counts below 200 cells/μl were excluded. Adverse events (AEs) including HIV-specific and laboratory safety parameters were recorded. Cell-mediated (ICS) and humoral (ELISA) responses were evaluated before vaccination, 1 month after each dose (D30, D60) and D210. RESULTS: Thirty-seven individuals [interquartile range (IQR) CD4⁺ cell counts at screening: 438-872 cells/μl; undetectable HIV-1 viremia] were enrolled; 73% of individuals reported previous BCG vaccination, 97.3% tested negative for the QuantiFERON-TB assay. For M72/AS01 recipients, no vaccine-related serious AEs or cART-regimen adjustments were recorded, and there were no clinically relevant effects on laboratory safety parameters, HIV-1 viral loads or CD4⁺ cell counts. M72/AS01 was immunogenic, inducing persistent and polyfunctional M72-specific CD4⁺ T-cell responses [medians 0.70% (IQR 0.37-1.07) at D60] and 0.42% (0.24-0.61) at D210, predominantly CD40L⁺IL-2⁺TNF-α⁺, CD40L⁺IL-2⁺ and CD40L⁺IL-2⁺TNF-α⁺IFN-γ⁺]. All M72/AS01 vaccines were seropositive for anti-M72 IgG after second vaccination until study end. CONCLUSION: M72/AS01 was clinically well tolerated and immunogenic in this population, supporting further clinical evaluation in HIV-infected individuals in TB-endemic settings.