Effects of diclofenac and dexamethasone on horse experimental endotoxemia

Quinze eqüinos machos, da raça Mangalarga, com idades entre dois e três anos, foram utilizados para se avaliar os possíveis efeitos clínicos benéficos da administração de dexametasona ou diclofenaco sódico durante a endotoxemia experimental em eqüinos. Os animais foram divididos em três grupos de cinco animais cada: controle (C), diclofenaco sódico (SD) e dexametasona (DM). Todos os grupos receberam 0,1µg/kg de lipopolissarídeo de Escherichia coli 055:B5, durante 15 minutos, por via intravenosa mais: grupo SD - 2,2mg/kg de SD, por via oral, 60 minutos antes da infusão da endotoxina; grupo DM - 1,1mg/kg, por via intravenosa, 30 minutos antes da endotoxina; grupo C - 20ml de NaCl 0,9%, por via intravenosa, 30 minutos antes da endotoxina. O SD não preveniu a leucopenia, neutropenia e linfopenia ocorridas três horas após a indução da endotoxemia, porém a DM atenuou essas alterações. As taxas de proteínas plasmática e peritoneal, a concentração de glicose e de fósforo inorgânico e a contagem de células nucleadas totais peritoneais mantiveram-se inalteradas. O diclofenaco foi eficaz na prevenção da febre e alterações nos borborigmos intestinais enquanto que a dexametasona bloqueou as alterações no número de células inflamatórias em relação ao grupo controle.

Virulência de Aphanocladium album (Preuss) Gams e Verticillium lecanii (Zimm.) Viégas (Deuteromycotina: Hyphomycetes) para o Percevejo-de-renda da seringueira, Leptopharsa heveae (Drake & Poor) (Hemiptera: Tingidae)

The lace bug, Leptopharsa heveae is an insect that causes serious damage on rubber trees. In laboratory condition, the strains of Verticillium lecanii (ARSEF 6430, 6431 e 6432) and Aphanocladium album (ARSEF 6433) were tested on third-and fifth-instar nymphs and adults of L. heveae to evaluate their virulence using 2.4 x 10(5) and 2.4 x 10(7) conidia/mL. The bioassays were carried out using Petri dishes whose inner bottoms were covered with damp filter papers. Each Petri dish contained five insects and one rubber tree leaflet. The plates were covered with PVC film to provide high relative humidity, maintained at 26 +/- 0.5 degrees C and a photophase of 14 hours. The Probit analysis was calculated from mortality date of insects killed by fungi. In the highest concentrations, ARSEF 6430 was more virulent for third instar nymphs, and the LT50 was 1.9 days. For the fifth instar, the strains ARSEF 6430, 6433 and 6432 showed similar virulence with LT50 of 2.6, 2.6 and 3.2 days, respectively. For adults, ARSEF 6431 was the most virulent strain with the LT50 recorded at 2.0 days. The smallest concentration did not always cause more than 50% mortality.

A elasticidade do ligamento colateral medial da articulação do cotovelo de cão não advém de elastina

A literatura relata que ligamentos consistem de tecido conjuntivo denso, composto por água, colágeno tipos I e III, diversas proteoglicanas, pouca elastina e várias outras substâncias. Além disso, os ligamentos, quando testados in vitro com tensão longitudinal e unidirecional, apresentam um comportamento mecânico não-linear, ou seja, as fibras colágenas são alongadas aos poucos, perdendo seu padrão ondulado, até que todas estejam no limite máximo de tração e iniciem o rompimento. Portanto, no presente estudo avaliou-se a presença de fibras elásticas (elastina) no ligamento colateral medial do cotovelo de cães adultos para ponderar se a elasticidade do referido ligamento deve-se à presença de fibras elásticas ou às propriedades elásticas do colágeno ou à combinação de ambas. Foram utilizadas quatro articulações, de machos e fêmeas em igual proporção, das quais foram adquiridas as amostras das porções médias dos ligamentos colaterais mediais para a rotina histológica. Os cortes foram corados pela técnica de Weigert, e não foi observada a presença de fibras elásticas, detectável por esta técnica à microscopia de luz. Concluiu-se que a elasticidade do ligamento colateral medial do cotovelo de cão deve-se, principalmente, ao padrão ondulado das fibras colágenas, devido à quantidade ínfima ou até à inexistência de fibras elásticas nesta estrutura.

Custo social de oportunidade na trajetória de acesso ao ensino superior: o caso dos ingressantes na UFRN nos vestibulares de 2006 a 2010

Access is a problem of higher education in Brazil that has existed since the formalization of this has occurred since the installation of the Portuguese court in Brazil in 1808. Only 10% of young people between 18 and 24 years of age attending this level of education in 2000, arriving in 2010 just 15%, far from that determined the National Education Plan in 2001, triple that percentage by the year 2010. In addition, a majority of seats of public HEIs is populated by students from the private network, especially in high-demand courses. In this context, this study aims to identify the costs related to the trajectories of students who were successful in the vestibular UFRN editions from 2006 to 2010. Presents an overview of higher education in Brazil, a brief history of vestibular, as well as new forms of access, and some of the policies to expand such access, highlighting the argument Inclusion UFRN. Focusing on the theme of the paper presents the concepts of opportunity costs and social. After collecting data through a questionnaire and consultation of databases COMPERVE was developed to search for a descriptive and analytical, with the participation of 3,995 students, of whom 1642 (41.1%) had completed secondary education in schools public, and 2,078 (52%) in private schools. The profile indicates that 90% are single, about 50% are 21 years of age, are white and female. In the course of preparation for college entrance exams, 80% chose the course during or after completion of the last year of high school, and almost 70% said they had started preparing at that time. Findings related to the costs involved with this preparation indicate that, in most cases there were school fees and disbursements and workshops, and the purchase of books and other materials, with parents primarily responsible for this cost, the amount disbursed each month was up $ 300 for 64% of respondents and only 7% of them exceeded $ 1,000, the major non-financial costs were characterized by the following resignations: job opportunities (24%) or temporary work (20%) courses of languages (26%), leisure activities (48%), leisure travel (43%), and parties and / or shows (54%). Of social investments by the government, stand out in the tax waiver scholarships for study in private institutions, grant exemption from the registration fee of vestibular, the preparatory courses UFRN, and seminars by COMPERVE / UFRN with networks of high school. From the junction of the opportunity costs (private costs) and social costs (public costs), a new concept: the social opportunity cost, which measures the combined efforts of families and government to finance the opportunity to access higher education of an individual. This concept can and should be incorporated as a strategic vector for the sake of democratic university, which reflects the social model that is sought

Utilização de medidas biométricas para predizer características da carcaça de cabritos Saanen

Foram determinadas medidas biométricas de caprinos leiteiros com o objetivo de estimar equações que permitam predizer o peso e as características da carcaça de animais sob diferentes condições nutricionais. Realizou-se um experimento em duas fases, utilizando-se 27 cabritos machos da raça Saanen em cada uma, distribuídos nos tratamentos: alimentação à vontade, 30 e 60% de restrição. O peso vivo (PV) inicial foi de 5 kg na Fase 1 e 20 kg na Fase 2, abatendo-se os animais ao atingirem 20 e 35 kg de PV, respectivamente. Foram determinadas as medidas biométricas e avaliada a condição corporal no animal vivo e, após o abate e resfriamento de 24 horas, as medidas da carcaça. Estimaram-se o peso em jejum (PJ), o peso da carcaça fria (PCF) e a compacidade da carcaça, em função das medidas biométricas. O perímetro torácico e o comprimento corporal foram as medidas biométricas que apresentaram melhor ajuste para estimar o PJ, o PCF e a compacidade da carcaça e, por isso, são recomendados, por serem precisos, práticos e de fácil execução.

Uma abordagem histórica para o ensino do princípio da inércia

Placed in the field of Didactic of Science, this paper proposes an approach to the introduction of the History of Science in science education, at high school level. It was designed and implemented a series of activities regarding the history of the Principle of Inertia. The aim of this approach was to give more meaning to scientific education, while opening new avenues for a better understanding of the processes of construction of scientific knowledge. The preparation of the activities involved a study of the historical development of the concept of motion, from the Aristotelian physics through physical movement concepts at medieval period, from Galileo, Gassendi, Descartes, until the first law of Newton. The strategy of teaching was applied to three classes of high school (night period) of a state public school at the city of Natal (RN). The results indicated the difficulty of overcoming alternative conceptions about movement by students. Nevertheless, we consider that the implementation of this strategy of teaching both represented gains for the learning of students, and contributed to the resizing of pedagogical practices of the teacher-researcher

A dialética do amor em pigmaleão, de G. B. Shaw.

Pygmalion (1913), by George Bernard Shaw (1856-1950), has many studies in literary criticism. However, this study brings a new interpretation to Shaw s play based on Harold Bloom s theory and methodology, that is, the anxiety of influence and the dialectic of revisionism. Through the analysis of poetic influence and the dialectic of love, we can see that Pygmalion represents an apophrades in relation to William Shakespeare s The Taming of the Shrew (1593) and Ovid s myth of Pygmalion and Galatea in Metamorphosis (c. 14), which creates a family romance between the three stories. Shaw s play surpasses The Taming of the Shrew when it shows the possibility of the relation between this parent poem and Ovid s myth, which it is also its parent poem, and because it represents a strong misreading of Shakespeare s play as well as of Ovid s myth.

Development and validation of a new and rapid HPLC for determination of lyophilized teicoplanin

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Performances da escrita

Este artigo aponta as características de uma escrita performática a partir do cruzamento entre o discurso ficcional, o discurso filosófico e o discurso crítico como formas equivalentes de experiência. Busca-se compreender os diferentes contextos em que a performance, como campo de experimentação, invade a área dos estudos literários, produzindo efeitos de deslocamento do cânone e seus modos de legitimidade, bem como visa a problematizar os lugares determinados do emissor e do receptor do texto; do artista, do filósofo e do crítico

Climate and acute/subacute paracoccidioidomycosis in a hyper-endemic area in Brazil

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Ascorbic acid degradation kinetics in tomatoes at different drying conditions

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Kinematics of a spacetime with an infinite cosmological constant

A solution of the sourceless Einstein's equation with an infinite value for the cosmological constant L is discussed by using Inonu-Wigner contractions of the de Sitter groups and spaces. When Lambda --> infinity, spacetime becomes a four-dimensional cone, dual to Minkowski space by a spacetime inversion. This inversion relates the four-cone vertex to the infinity of Minkowski space, and the four-cone infinity to the Minkowski light-cone. The non-relativistic limit c --> infinity. is further considered, the kinematical group in this case being a modified Galilei group in which the space and time translations are replaced by the non-relativistic limits of the corresponding proper conformal transformations. This group presents the same abstract Lie algebra as the Galilei group and can be named the conformal Galilei group. The results may be of interest to the early Universe Cosmology.

De Sitter Relativity: a New Road to Quantum Gravity?

The Poincar, group generalizes the Galilei group for high-velocity kinematics. The de Sitter group is assumed to go one step further, generalizing Poincar, as the group governing high-energy kinematics. In other words, ordinary special relativity is here replaced by de Sitter relativity. In this theory, the cosmological constant I > is no longer a free parameter, and can be determined in terms of other quantities. When applied to the whole universe, it is able to predict the value of I > and to explain the cosmic coincidence. When applied to the propagation of ultra-high energy photons, it gives a good estimate of the time delay observed in extragalactic gamma-ray flares. It can, for this reason, be considered a new paradigm to approach the quantum gravity problem.

Superfluid Bose-Fermi mixture from weak coupling to unitarity

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Quantum mechanics versus equivalence principle

We consider the scattering of a photon by a weak gravitational field, treated as an external field, up to second order of the perturbation expansion. The resulting cross section is energy dependent which indicates a violation of Galileo's equivalence principle (universality of free fall) and, consequently, of the classical equivalence principle. The deflection angle theta for a photon passing by the sun is evaluated afterward and the likelihood of detecting Delta theta/theta(E) theta-theta(E)/theta(E) (where theta(E) is the value predicted by Einstein's geometrical theory for the light bending) in the foreseeable future, is discussed.