Construction of ethics in clinical research - Clinical trials registration

Scientific development that has been achieved through decades finds in clinical research a great possibility of translating findings to human health application. Evidence given by clinical trials allows everyone to have access to the best health services. However, the millionaire world of pharmaceutical industries has stained clinical research with doubt and improbability. Study results (fruits of controlled clinical trials) and scientific publications (selective, manipulated and with wrong conclusions) led to an inappropriate clinical practice, favoring the involved economic aspect. In 2005, the International Committee of Medical Journal Editors (ICMJE), supported by the World Association of Medical Editors, started demanding as a requisite for publication that all clinical trials be registered at the database ClinicalTrials.gov. In 2006, the World Health Organization (WHO) created the International Clinical Trial Registry Platform (ICTRP), which gathers several registry centers from all over the world, and required that all researchers and pharmaceutical industries register clinical trials. Such obligatory registration has progressed and will extend to all scientific journals indexed in all worldwide databases. Registration of clinical trials means another step of clinical research towards transparency, ethics and impartiality, resulting in real evidence to the forthcoming changes in clinical practice as well as in the health situation.

Committees for ethics in research involving human subjects

In Brazil since October 1996 there have been guidelines for research involving human subjects. Now human subjects know when their treatment is part of research. Deceit is no longer tolerated. But is not enough to say we offer an explanation to the potential subject and we offer a choice before he or she is confronted with an informed consent form. As in all professional activity, scientific investigation needs social controls. In Brazil, the ultimate responsibility of an investigation lies on the investigator, but in every institution where research is carried out there is a Committee for Ethics in Research. All Committees are subordinated to the National Commission of Ethics in Research, which is submitted to the Brazilian Institute of Health. During 2005 around 17,000 protocols involving 700,000 human subjects were revised by 475 Committees distributed all over the country. Approximately 7,000 people are now working in these Committees.

Da geografia medieval às origens da geografia moderna: contrastes entre diferentes noções de natureza, espaço e tempo

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

De versos e trovas: análise de aspectos fonoestilísticos do português medieval por meio das “Cantigas de Santa Maria”

Pós-graduação em Linguística e Língua Portuguesa - FCLAR

Rumores da escrita, vestígios do passado: uma interpretação fonológica das vogais do português arcaico por meio da poesia medieval

A proposta do presente livro é oferecer ao leitor uma descrição fonológica das qualidades vocálicas vigentes na primeira fase (período trovadoresco) do português arcaico a partir da análise das rimas e da grafia das Cantigas de Santa Maria, de Afonso X, o Sábio, Rei de Leão e Castela, elaboradas na segunda metade do século XIII.

Library Classifications Criticism: Universality, Poststructuralism and Ethics

We study library classifications criticisms from a poststructuralist and pragmatist point of view that rejects the idea of universality in knowledge organization systems. From this perspective, we analize the seminal texts on library classifications criticisms and conclude that the seek of neutrality in some of these texts is not only an impossible goal but also a contradiction in the representation of different cultures. Therefore, we suggest the commitment with the goals and the recognition of bias in library classifications as an important device for achieving a transcultural ethics in knowledge organization and representation.

A misosoginia medieval e seus ecos nos Lais de Maria de França

The Lais of Marie de France are a specific type of historical record about the medieval aristocratic society and enables us to decipher the hierarchies that govern the relationship between men and women in the period. As well explains Georges Duby, medieval society tends to present coated with a male character because, among other factors, its latent misogyny. Women were placed under male authority, convinced of their natural superiority , the men despised , mocked her sex , meanwhile feared them, after all, women were Eve’s daughters. So, Lais offer female images that cannot be ignored , since it express the author women’s idea. However , as we seek to demonstrate in this article, Maria of France reflects the representations of the Christian society aristocratic. One note here that this article does not aspire to reach the actual circumstances, but the historical significance of female images present in the Lais.

A Poética do amor em O Romance da Rosa

We aim with this article to analyze the poetics of love in The Romance of the Rose. We think that Guillaume de Lorris’s conception of love is associated with the flourishing of the French courtly society of the XIII Century, and that Jean de Meun’s conception of love is a result of the decline of this same society. Behind the virtues offered by Guillaume to the medieval lover we find the notion of courtesy, of the art of living in society, the understanding of the poetry as a form of ethics, and the medieval poetic of desire – intimately associated with the religious mysticism appeared from the XI Century and with the troubadours’ poetry. Jean is more influenced by the Ovidian tradition of thinking about the causes and effects of love. In the first part of the poem, Guillaume idealizes the conquest of the Rose; in the second, Jean describes the cueillette of the Rose, which could be read as a rape, in an allegorical way. It is this tension between different conceptions of love in a same poem that makes possible a better comprehension of the ways people used to think and feel in the Middle Ages.

A Sancta Sapientia Medieval: enigma e mistério no teatro cristão de Rosvita de Ganderseheim

Within the scope of Literary Studies, theory, criticism, and historiography about the literature produced in the Middle Ages developed considerably from 1940 on, with the works of Ernst Curtius, Mikhail Bakhtin, and Erich Auerbach. In spite of the progress made, some specific aspects remain in the shadow, with incursions which were punctual though meaningful: that is the case of the critic fortunes about women‟s literary production in that period. Rosvita was a canoness and lived in the Benedictine convent of Gandersheim (Germany), in the 10th century A.D. Coming under Terence‟s influence, she wrote theater plays in Latin in which she figuratively presented theological issues in order to spread the Christian doctrine. The martyrdom issue deserved to be put in relief and was the focal point of the play Wisdom, which took place at the time of the Roman emperor Adrian. This paper analyzes that dramatic text discussing, at the end, how the categories of symbol, enigma, allegory, and mystery are organized by the author as expressive resources and structural elements.

Entre santos e demônios: a percepção do mal na teologia e hagiografias do Reino Visigodo de Toledo (séculos VI-VII)

Pós-graduação em História - FCLAS

Improving business innovation and research through the application of neuromarketing with ethics: a framework

The objective of this paper is to analyse and to discuss the ethical issues in the field of research known as neuromarketing, a tool used to improve innovation in companies. It uses techniques available to neuroscientists, both newer and more sophisticated ones along with traditional ones, but now for new purposes. From the beginning, this new area has evoked discussions about ethical aspects related to the results presented. Despite the unrestricted controversy surrounding the theme, few studies have discussed ethical issues involved in this line of research in a pragmatic manner. In this sense, this paper seeks to analyse and discuss ethical issues in neuromarketing research through a literature review and the proposal for a framework of ethical mapping. This framework revealed the ethical implications that would be most prominent in certain research situations: the purpose of utilising neuromarketing techniques, organisational type, and industrial sector, among others.

The Ethics of Implementation: Institutional Remedies and the Lawyer's Role

The issue addressed in this article is whether and to what extent a lawyer has an ethical responsibility to pursue implementation of the remedy in institutional reform litigation. Institutional reform litigation refers to cases in which an individual or class of individuals sues a large organization in order to vindicate constitutional or statutory rights. The types of cases with which this article is concerned are the "public law" type, such as school desegregation, prisoners' rights and patients' rights cases, although included under the rubric of institutional reform can be, inter alia, antitrust, reapportionment and bankruptcy cases. The implementation stage of institutional reform litigation arises after an individual or class of individuals prevails at the liability stage, or pursuant to a settlement, and a court orders the defendant organization to change in order to vindicate the plaintiffs' rights. At that point, the defendant organization, whether it be a prison, mental hospital or school district, usually has the burden of implementing the order. One conclusion drawn is that the ethical duty of the lawyer must always be consistent with the lawyer's "special responsibility for the quality of justice."