Correlation of temperature induced conformation change with optimum catalytic activity in the recombinant G/11 xylanase A from Bacillus subtilis strain 168 (1A1)

The 1.7 angstrom resolution crystal structure of recombinant family G/11 beta-1,4-xylanase (rXynA) from Bacillus subtilis 1A1 shows a jellyroll fold in which two curved P-sheets form the active-site and substrate-binding cleft. The onset of thermal denaturation of rXynA occurs at 328 K, in excellent agreement with the optimum catalytic temperature. Molecular dynamics simulations at temperatures of 298-328 K demonstrate that below the optimum temperature the thumb loop and palm domain adopt a closed conformation. However, at 328 K these two domains separate facilitating substrate access to the active-site pocket, thereby accounting for the optimum catalytic temperature of the rXynA. (c) 2005 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.

Superstrings in 2D backgrounds with R-R flux and new extremal black holes

The hybrid formalism is used to quantize the superstring compactified to two-dimensional target-space in a manifestly spacetime supersymmetric manner. A quantizable sigma model action is then constructed for the type II superstring in curved two-dimensional supergravity backgrounds which can include Ramond-Ramond flux. Such curved backgrounds include Calabi-Yau fourfold compactifications with Ramond-Ramond flux, and new extremal black hole solutions in two-dimensional dilaton supergravity theory. These black hole solutions are a natural generalization of the CGHS model and might be possible to describe using a supergroup version of the SL(2, R)/U(1) WZW model. We also study some dynamical aspects of the new black holes, such as formation and evaporation. (C) 2001 Published by Elsevier B.V. B.V.

Ten-dimensional supergravity constraints from the pure spinor formalism for the superstring

It has recently been shown that the ten-dimensional superstring can be quantized using the BRST operator Q = philambda(alpha)d(alpha), where lambda(alpha) is a pure spinor satisfying; lambdagamma(m)lambda = 0 and dalpha is the fermionic supersymmetric derivative. In this paper, the pure spinor version of superstring theory is formulated in a curved supergravity background and it is shown that nilpotency and holomorphicity of the pure spinor BRST operator imply the on-shell superspace constraints of the supergravity background. This is shown to lowest order in alpha' for the heterotic and Type II superstrings, thus providing a compact pure spinor version of the ten-dimensional superspace constraints for N = 1 Type IIA and Type IIB supergravities. Since quantization is straightforward using the pure spinor version of the superstring, it is expected that these methods can also be used to compute higher-order alpha' corrections to the ten-dimensional superspace constraints. (C) 2002 Elsevier B.V. B.V. All rights reserved.

N=2 sigma models for Ramond-Ramond backgrounds

Using the U(4) hybrid formalism, manifestly N = (2,2) worldsheet supersymmetric sigma models are constructed for the type-IIB superstring in Ramond-Ramond backgrounds. The Kahler potential in these N = 2 sigma models depends on four chiral and antichiral bosonic superfields and two chiral and antichiral fermionic superfields. When the Kahler potential is quadratic, the model is a free conformal field theory which describes a flat ten-dimensional target space with Ramond-Ramond flux and non-constant dilaton. For more general Kahler potentials, the model describes curved target spaces with Ramond-Ramond flux that are not plane-wave backgrounds. Ricci-flatness of the Kahler metric implies the on-shell conditions for the background up to the usual four-loop conformal anomaly.

Swimming versus swinging effects in spacetime

Wisdom has recently unveiled a new relativistic effect, called spacetime swimming, where quasirigid free bodies in curved spacetimes can speed up, slow down or deviate their falls by performing local cyclic shape deformations. We show here that for fast enough cycles this effect dominates over a nonrelativistic related one, named here space swinging, where the fall is altered through nonlocal cyclic deformations in Newtonian gravitational fields. We expect, therefore, to clarify the distinction between both effects leaving no room to controversy. Moreover, the leading contribution to the swimming effect predicted by Wisdom is enriched with a higher order term and the whole result is generalized to be applicable in cases where the tripod is in large redshift regions.

Quantization of the superstring in Ramond-Ramond backgrounds

Sigma model actions are constructed for the type II superstring compactified to four-and six-dimensional curved backgrounds which can contain non-vanishing Ramond-Ramond fields. These actions are N = 2 worldsheet superconformally invariant and can be covariantly quantized preserving manifest spacetime supersymmetry. They are constructed using a hybrid Version of superstring variables which combines features of the Ramond-Neveu-Schwarz and Green-Schwarz formalisms. For the AdS(2) x S-2 and AdS(3) x S-3 backgrounds, these actions differ from the classical Green-Schwarz actions by a crucial kinetic term for the fermions. Parts of this work have been done in collaborations with M Bershadsky, T Hauer, W Siegel, C Vafa, E Witten, S Zhukov and B Zwiebach.

Teleparallel origin of the Fierz picture for spin-2 particle

A new approach to the description of a spin-2 particle in flat and curved spacetime is developed on the basis of the teleparallel gravity theory. We show that such an approach is in fact a true and natural framework for the Fierz representation proposed recently by Novello and Neves. More specifically, we demonstrate how the teleparallel theory fixes uniquely the structure of the Fierz tensor, discover the transparent origin of the gauge symmetry of the spin-2 model, and derive the linearized Einstein operator from the fundamental identity of the teleparallel gravity. In order to cope with the consistency problem on the curved spacetime, similarly to the usual Riemannian approach, one needs to include the nonminimal (torsion dependent) coupling terms.

Conformal coupling and Foldy-Wouthuysen transformation

The propagation of a free scalar field phi with mass m in a curved background is generally described by the equation (g(munu) delmudelnu + m(2) + xiR)phi = 0. There exist some arguments in the literature that seem to favor the conformal coupling to the detriment of the minimal one. However, the majority of these claims axe inconclusive. Here we show that the exact Foldy Wouthuysen transformation for spin-0 particle coupled to a wide class of static spacetime metrics exists independently of the value of. Nevertheless, if the coupling is of the conformal type, the gravitational Darwin-like term has an uncomplicated structure and it is proportional to the corresponding term in the fermionic case. In addition, an independent computation of this term, which has its origin in the zitterbewegung fluctuation of the boson's position with the mean square <(deltar)(2)> approximate to 1/m(2), gives a result that coincides with that obtained using the aforementioned exact transformation with xi = 1/6.

Consistency of superspace low energy equations of motion of 4D Type II superstring with Type II sigma model at tree-level

We derive the torsion constraints and show the consistency of equations of motion of four-dimensional Type II supergravity in superspace. with Type II sigma model. This is achieved by coupling the four-dimensional compactified Type II Berkovits' superstring to an N = 2 curved background and requiring that the sigma-model has superconformal invariance at tree-level. We compute this in a manifestly 4D N = 2 supersymmetric way. The constraints break the target conformal and SU(2) invariances and the dilaton will be a conformal, SU(2) x U(1) compensator. For Type II superstring in four dimensions, worldsheet supersymmetry requires two different compensators. One type is described by chiral and anti-chiral superfields. This compensator can be identified with a vector multiplet. The other Type II compensator is described by twist-chiral and twist-anti-chiral superfields and can be identified with a tensor hypermultiplet. Also, the superconformal invariance at tree-level selects a particular gauge, where the matter is fixed, but not the compensators. After imposing the reality conditions, we show that the Type II sigma model at tree-level is consistent with the equations of motion for Type II supergravity in the string gauge. (C) 2003 Elsevier B.V All rights reserved.

Covariant quantization of the superstring

After reviewing the Green-Schwarz superstring using the approach of Siegel, the superstring is covariantly quantized by constructing a BRST operator from the fermionic constraints and a bosonic pure spinor ghost variable. Physical massless vertex operators are constructed and, for the first time, N-point tree amplitudes are computed in a manifestly ten-dimensional super-Poincare covariant manner. Quantization can be generalized to curved supergravity backgrounds and the vertex operator for fluctuations around AdS(5) x S-5 is explicitly constructed.

Taming the b antighost with Ramond-Ramond flux

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

THERMAL RADIATION FROM A FLUCTUATING EVENT HORIZON

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Extended 2D generalized dilaton gravity theories

We show that an anomaly-free description of matter in (1+1) dimensions requires a deformation of the 2D relativity principle, which introduces a non-trivial centre in the 2D Poincare algebra. Then we work out the reduced phase space of the anomaly-free 2D relativistic particle, in order to show that it lives in a noncommutative 2D Minkowski space. Moreover, we build a Gaussian wave packet to show that a Planck length is well defined in two dimensions. In order to provide a gravitational interpretation for this noncommutativity, we propose to extend the usual 2D generalized dilaton gravity models by a specific Maxwell component, which guages the extra symmetry associated with the centre of the 2D Poincare algebra. In addition, we show that this extension is a high energy correction to the unextended dilaton theories that can affect the topology of spacetime. Further, we couple a test particle to the general extended dilaton models with the purpose of showing that they predict a noncommutativity in curved spacetime, which is locally described by a Moyal star product in the low energy limit. We also conjecture a probable generalization of this result, which provides strong evidence that the noncommutativity is described by a certain star product which is not of the Moyal type at high energies. Finally, we prove that the extended dilaton theories can be formulated as Poisson-Sigma models based on a nonlinear deformation of the extended Poincare algebra.

Gravitação semiclássica

Fazemos aqui uma breve descrição da teoria semiclássica da gravitação que tem conseguido antecipar de forma bastante robusta alguns efeitos de gravitação quântica.

The effect of cooling rate during hydrothermal synthesis of ZnO nanorods

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)