The relationship among serum levels of manganese superoxide dismutase and mitochondrial DNA 8-hydroxy-2'- deoxyguanosine, and dietary antioxidants intake in type 2 diabetes

Oxidative stress plays a key role in the development of Type 2 Diabetes (T2D). This cross-sectional study examined the relationship among serum levels of manganese superoxide dismutase (MnSOD), 8-hydroxy-2’-deoxyguanosine (8OHdG), dietary antioxidant intakes and glycemic control in African Americans (n=209) and Haitian Americans (n=234) with and without T2D. ^ African Americans had higher BMI (32.8 vs. 29.3 kg/m2), higher energy intake (2148 vs. 1770 kcal), and were more educated as compared to Haitian Americans; all variables were significant at p < .001. Serum levels of 8OHdG and MnSOD for African Americans (1691.0 ± 225.1 pg/ml, 2538.0 ± 1091.8 pg/ml; respectively) were significantly higher than for Haitian Americans (1626.2 ± 222.9, 2015.8 ± 656.3 pg/ml; respectively). 8OHdG was negatively correlated with MnSOD ( r = -.167, p < .001) in T2D. Having T2D was negatively correlated with MnSOD (r = -.337; p < .01) and positively correlated with 8OHdG (r = .500; p < .01). African Americans and Haitian Americans with T2D had fasting plasma glucose (FPG) levels of 143.0 ± 61.0 mg/dl and 157.6 ± 65.5 mg/dl, and A1C of 7.5 ± 1.8 % and 8.4 ± 2.4 %, respectively. African Americans and Haitian Americans without T2D had FPG levels of 95.8 ± 13.2 mg/dl and 98.7 ± 16.9 mg/dl, and A1C of 5.9 ± 0.4% and 6.0 ± 0.5%, respectively. Dietary intakes of vitamin C and vitamin D were negatively correlated with FPG (r = -.21; r = -.19, p < .05) respectively. Carotenoids negatively correlated with A1C (r = -.19, p < .05). Lower levels of MnSOD were associated with lower levels of zinc, r = .10, p < .05, and higher levels of carotenoids r = -.10, p < .05. Higher levels of 8OHdG were associated with lower levels of Vitamin D, r = -.14, p < .01, and carotenoids, r = -.09, p < .05. ^ The results demonstrate greater oxidative mtDNA damage in persons with T2D compared to those without T2D and in African Americans compared with Haitian Americans. The inverse relationship between dietary intake of antioxidants and oxidative stress implies a potential to reduce oxidative stress with diet. ^

Ethnicity and reaccumulation : an ecological analysis

This study looks at the process of reaccumulation of resources in Miami following Hurricane Andrew. Emphasis is on differences between four major ethnic groups: Anglos, African- Americans, Cubans and non-Cuban Hispanics. Secondary data is used to analyze measures of housing recovery on a census block group level. Results indicate that, while there are ethnic consequences on a block groups level, support for enclave hypotheses are equivocal.

Navigating the past, envisioning the future : Octavia Butler's heroines

In this thesis, I examined three novels by African American science fiction novelist Octavia Butler: Kindred (1979), Parable of the Sower (1994), Parable of the Talents (1998) and Dawn (1987). I analyzed Butler's belief that society has become too firmly attached to old customs and belief systems, initiating destructive, self-defeating cycles in our history. She looks to African American females to take up leadership roles and exact radical change to ensure society's continued survival as well as progress, acceptance and autonomy within our communities. I also established Butler's significant contributions to the African American literary canon as she examines the history of African Americans and speculates on their necessary roles of shaping the future of society.

Coretta King at International Women's Year conference

General note: Title and date provided by Bettye Lane.

Women United for Action demonstrate against high food prices at supermarkets

General note: Title and date provided by Bettye Lane.

New York Congresswoman Shirley Chisholm at the Democratic National Convention in Miami

General note: Title and date provided by Bettye Lane.

"Sexism in the Schools" conference at P.S. 41 about the changing roles of women in Africa and America

General note: Title and date provided by Bettye Lane.

Meeting at Del Prado Hotel for the Nongovernmental Organization

General note: Title and date provided by Bettye Lane.

Ella Baker, Founder of Student Nonviolent Coordinating Committee (SNCC)

General note: Title and date provided by Bettye Lane.

Ann Mentor, owner of P.R. Firm in New York

General note: Title and date provided by Bettye Lane.

Union meeting

General note: Title and date provided by Bettye Lane.

Eleanor Holmes Norton and NY delegate after abortion resolution passes

General note: Title and date provided by Bettye Lane.

Tired demonstrators at children's march for survival

General note: Title and date provided by Bettye Lane.

Black caucus at NOW conference, Houston

General note: Title and date provided by Bettye Lane.

Day care demonstration at City Hall

General note: Title and date provided by Bettye Lane.