Analysis of phasic and tonic electromyographic signal characteristics: electromyographic synthesis and comparison of novel morphological and linear-envelope approaches

The pattern of tonic and phasic components in an EMG signal reflects the underlying behaviour of the central nervous system (CNS) in controlling the musculature. One avenue for gaining a better understanding of this behaviour is to seek a quantitative characterisation of these phasic and tonic components. We propose that these signal characteristics can range between unvarying, tonic and intermittent, phasic activation through a continuum of EMG amplitude modulation. In this paper, we present two new algorithms for quantifying amplitude modulation: a linear-envelope approach, and a mathematical morphology approach. In addition we present an algorithm for synthesising EMG signals with known amplitude modulation. The efficacy of the synthesis algorithm is demonstrated using real EMG data. We present an evaluation and comparison of the two algorithms for quantifying amplitude modulation based on synthetic data generated by the proposed synthesis algorithm. The results demonstrate that the EMG synthesis parameters represent 91.9% and 96.2% of the variance of linear-envelopes extracted from lumbo-pelvic muscle EMG signals collected from subjects performing a repetitive-movement task. This depended, however, on the muscle and movement-speed considered (F=4.02, p<0.001). Coefficients of determination between input and output amplitude modulation variables were used to quantify the accuracy of the linear-envelope and morphological signal processing algorithms. The linear-envelope algorithm exhibited higher coefficients of determination than the most accurate morphological approach (and hence greater accuracy, T=8.16, p<0.001). Similarly, the standard deviation of the coefficients of determination was 1.691 times smaller (p<0.001). This signal processing algorithm represents a novel tool for the quantification of amplitude modulation in continuous EMG signals and can be used in the study of CNS motor control of the musculature in repetitive-movement tasks.

Multiple days of heat exposure on firefighters' work performance and physiology

This study assessed the accumulated effect of ambient heat on the performance of, and physiological and perceptual responses to, intermittent, simulated wildfire fighting tasks over three consecutive days. Firefighters (n = 36) were matched and allocated to either the CON (19°C) or HOT (33°C) condition. They performed three days of intermittent, self-paced simulated firefighting work, interspersed with physiological testing. Task repetitions were counted (and converted to distance or area) to determine work performance. Participants were asked to rate their perceived exertion and thermal sensation after each task. Heart rate, core temperature (Tc), and skin temperature (Tsk) were recorded continuously throughout the simulation. Fluids were consumed ad libitum. Urine volume was measured throughout, and urine specific gravity (USG) analysed, to estimate hydration. All food and fluid consumption was recorded. There was no difference in work output between experimental conditions. However, significant variation in performance responses between individuals was observed. All measures of thermal stress were elevated in the HOT, with core and skin temperature reaching, on average, 0.24 ± 0.08°C and 2.81 ± 0.20°C higher than the CON group. Participants' doubled their fluid intake in the HOT condition, and this was reflected in the USG scores, where the HOT participants reported significantly lower values. Heart rate was comparable between conditions at nearly all time points, however the peak heart rate reached each circuit was 7 ± 3% higher in the CON trial. Likewise, RPE was slightly elevated in the CON trial for the majority of tasks. Participants' work output was comparable between the CON and HOT conditions, however the performance change over time varied significantly between individuals. It is likely that the increased fluid replacement in the heat, in concert with frequent rest breaks and task rotation, assisted with the regulation of physiological responses (e.g., heart rate, core temperature).

Fluctuations of redox conditions across the Permian–Triassic boundary : new evidence from the GSSP section in Meishan of South China

Oceanic anoxia has long been considered as one of the main causes for the end-Permian mass extinction. However, the results obtained by different researchers are rather divergent from different sections, or even on the same section using the same redox proxy. This study aims to examine the causes for some of these divergent results using high-resolution pyrite framboid sampling at the Meishan GSSP section in South China. Detailed microfacies analysis shows that the uppermost Late Permian strata comprises two significantly different sedimentary facies: one characterized by silicious muddy limestone and recognized as representing autochthonous background sediments; the other distinguished by bioclastic grainstone, interpreted to be allochthonous in origin and have been transported from the nearby platform margin. These two different sedimentary facies represent two distinctly different redox conditions. Together with the facies analysis, a statistical analysis of pyrite framboids was carried out to evaluate the redox evolution across the Permian-Triassic boundary. Abundant framboids with average diameters of about 6μm are found in background sediments beneath the extinction boundary, indicating generally anoxic bottom water conditions. But this condition was punctuated by transient intervals of rapid oxygenation interpreted to have been caused by intrusion of intermittent turbidity flows. Our study also showed that anoxic conditions persisted into the immediate aftermath of the mass extinction, thereafter it was quickly followed by a relatively long period of oxic conditions (with rare framboids). However, the redox conditions returned to anoxia (with abundant pyrite framboids averaging about 5μm in diameter), accompanied by a rapid global transgression. The oxygenation manifested near the Permian-Triassic boundary coincides with the negative excursion of carbon isotope. This would imply that, contrary to previous interpretations, this great δ13C negative excursion was probably not caused by the upwelling of anoxic deep ocean waters.

An improved stochastic modeling of opportunistic routing in vehicular CPS

Vehicular Cyber-Physical System (VCPS) provides CPS services via exploring the sensing, computing and communication capabilities on vehicles. VCPS is deeply influenced by the performance of the underlying vehicular network with intermittent connections, which make existing routing solutions hardly to be applied directly. Epidemic routing, especially the one using random linear network coding, has been studied and proved as an efficient way in the consideration of delivery performance. Much pioneering work has tried to figure out how epidemic routing using network coding (ERNC) performs in VCPS, either by simulation or by analysis. However, none of them has been able to expose the potential of ERNC accurately. In this paper, we present a stochastic analytical framework to study the performance of ERNC in VCPS with intermittent connections. By novelly modeling ERNC in VCPS using a token-bucket model, our framework can provide a much more accurate results than any existing work on the unicast delivery performance analysis of ERNC in VCPS. The correctness of our analytical results has also been confirmed by our extensive simulations.

Establishing trust relationships in OppNets using Merkle trees

Opportunistic Networks (OppNets) are exposed to a variety of attacks, among them are packet dropping attacks. The security challenges in OppNets is to effectively and securely forward data and guarantee their delivery without any loss. Security and trust in OppNets have gained popularity in research because of their inherent features, including frequent partitions, long delays and intermittent connectivity. This paper presents an efficient malicious path and malicious node detection technique against selective packet dropping attacks. In our algorithm we have developed a solid detection mechanism using the Merkle tree hashing technique. The result of malicious path detection is used to build trust by destination nodes for each path, the built trust value of nodes is then used to detect malicious nodes. Simulation results show that the technique accurately detects malicious paths. The results also show that with the increase of simulation time, node detection accuracy also increases as intermediate nodes have more time to establish trust with destination nodes.

Metabolic power method underestimates energy expenditure in field sport movements using a GPS tracking system

The purpose of this study was to assess the validity of a GPS tracking system to estimate energy expenditure (EE) during exercise and field sport locomotor movements. Twenty-seven participants each completed one 90 minute exercise session on an outdoor synthetic futsal pitch. During the exercise session participants wore a 5 Hz GPS unit interpolated to 15 Hz (SPI HPU, GPSports Pty Ltd, Australia) and a portable gas analyser (Metamax® 3B, Cortex Pty Ltd, Germany) which acted as the criterion measure of EE. The exercise session was comprised of alternating five minute exercise bouts of randomised walking, jogging, running or a field sport circuit (x3) followed by 10 minutes of recovery. One-way ANOVA showed significant (p<0.01) and very large underestimations between GPS metabolic power derived EE and VO2 derived EE for all field sport circuits (% difference ≈ -44%). No differences in EE were observed for the jog (7.8%) and run (4.8%) while very large overestimations were found for the walk (43.0%). The GPS metabolic power EE over the entire 90 minute session was significantly lower (p<0.01) than the VO2 EE, resulting in a moderate underestimation overall (-19%). The results of this study suggest that a GPS tracking system using the metabolic power model of EE does not accurately estimate EE in field sport movements or over an exercise session consisting of mixed locomotor activities interspersed with recovery periods; however is able to provide a reasonably accurate estimation of EE during continuous jogging and running.

Acumulação de competências tecnológicas e os processos subjacentes de aprendizagem na indústria Mmtal - mecânica : o caso da empresa AGCO comércio e indústria LTDA em Santa Rosa - RS

This dissertation enfoca the relationship between technological competences accumulation and the learning underlying processes. This relationship is examined in the company AGCO Comércio and Indústria Ltda, during the period of 1970 to 2000. It is of a company metal-mechanics, agricultural machines manufacturer. In other words, the dissertation examines the processes technological learning implications for aA technological competences accumulation in the company in study. The dissertation enfoca the competences accumulation for three technological functions: processes and organization, products and equipments. The learning processes are examined to the light of four characteristic: variety, intensity, operation and interaction, from the structure existing analysis use in the literature. Based on study of individual case, this study found that the technological competences ways to accumulation in the studied company are associates to the several processes used to acquire technological knowledge and converts him in organizacional. Ademais, the simple incidence of these processes in the company didn't guarantee in the company a positive implication for the technological competences accumulation. The company accumulated level middleman-superior technological competence (level 6) to accomplish production and function products function processes and organization activities, and intermediary level (level 5) to accomplish function equipments activities. In haves to characteristic key, the learning processes introduce an oscillation differentiated along time: the variety oscillated of moderated the several; the intensity of intermittent the continuous; the operation of bad the good; and the interaction of weak the strong. Through the existing structure use in the literature, however applied to a previous studies different industry, this dissertation suggests that must there be an organized , continuous effort and integrated for the knowledge generation and sowing in every company in order to the technological training accumulation be accelerated in the company.

Resposta urodinamica ao cateterismo vesical intermitente e cloreto de oxibutinina em crianças com mielomeningocele

Examinamos urodinamicamente 46 crianças com mielomeningocele que foram classificadas em pressão de perda do detrusor maior de 40 cmH2O (33 pacientes) ou menor de 40 cmH2O (13 pacientes). As variáveis estudadas foram: idade, sexo, pressão intravesical, complacência vesical, contrações vesicais não-inibidas, capacidade vesical, tipo de esfíncter, hidronefrose, refluxo vesicoureteral e cicatriz renal. Os pacientes com pressão de perda do detrusor maior de 40 cmH2O foram tratados com cateterismo vesical intermitente limpo 4 x/dia e cloreto de oxibutinina na dose de 0,2 mg/kg/dose 3 x/dia. Após 30 dias de tratamento, avaliamos a resposta urodinâmica da pressão intravesical, complacência vesical, contrações vesicais não-inibidas e capacidade vesical. A idade dos pacientes com pressão de perda alta é significativamente maior. O sexo não foi significativamente diferente entre os dois grupos. A pressão intravesical e contrações vesicais não-inibidas são significativamente maiores nos pacientes com pressão de perda alta e a complacência vesical é significativamente menor nestes casos. Não houve correlação significativa entre capacidade vesical e pressão de perda. Também não houve correlação significativa entre o tipo de esfíncter e a capacidade vesical, contrações não-inibidas e pressão intravesical. Os pacientes com dissinergia apresentam significativamente menor complacência vesical e aqueles com sinergia apresentam significativamente maior complacência vesical. A dissinergia esteve significativamente associada aos pacientes com pressão de perda alta. Os pacientes com hidronefrose apresentam significativamente maior capacidade vesical e estão correlacionados significativamente com dissinergia e cicatriz renal. Não houve correlação significativa entre hidronefrose e pressão intravesical, complacência vesical, contrações vesicais não-inibidas e pressão de perda.Também não houve correlação significativa entre refluxo vesicoureteral e capacidade vesical, pressão intravesical, complacência vesical, contrações vesicais não-inibidas, tipo de esfíncter e pressão de perda, mas houve associação significativa com hidronefrose e cicatriz renal. Os pacientes com cicatriz renal apresentam significativamente maior capacidade vesical, mas não houve correlação significativa entre cicatriz renal e pressão intravesical, complacência vesical, contrações vesicais não-inibidas, tipo de esfíncter e pressão de perda. A média da pressão intravesical inicial era 60,5 cmH2O e diminuiu significativamente para 50,2 cmH2O após o tratamento. A complacência vesical média era 2,8 ml/cmH2O inicialmente e aumentou significativamente para 5,2 ml/cmH2O. A média das contrações vesicais não-inibidas inicial era 37 cmH2O e diminuiu significativamente para 11,4 cmH2O. A capacidade vesical média inicial era 133,9 ml e aumentou significativamente para 215,3 ml. Houve significativa melhora nos parâmetros urodinâmicos com o tratamento que, contudo, não conseguiu atingir valores considerados normais. Isto pode ser explicado pelas alterações viscoelásticas que já tenham ocorrido nestas bexigas e pela provável presença de outros neurotransmissores envolvidos na neurofisiologia patológica. Este trabalho deixa em aberto a possibilidade de que doses mais elevadas de cloreto de oxibutinina usadas por períodos mais prolongados possam ter efeitos benéficos adicionais aos aqui demonstrados.

A (semi-)parametric functional coefficient autoregressive conditional duration model

In this paper, we propose a class of ACD-type models that accommodates overdispersion, intermittent dynamics, multiple regimes, and sign and size asymmetries in financial durations. In particular, our functional coefficient autoregressive conditional duration (FC-ACD) model relies on a smooth-transition autoregressive specification. The motivation lies on the fact that the latter yields a universal approximation if one lets the number of regimes grows without bound. After establishing that the sufficient conditions for strict stationarity do not exclude explosive regimes, we address model identifiability as well as the existence, consistency, and asymptotic normality of the quasi-maximum likelihood (QML) estimator for the FC-ACD model with a fixed number of regimes. In addition, we also discuss how to consistently estimate using a sieve approach a semiparametric variant of the FC-ACD model that takes the number of regimes to infinity. An empirical illustration indicates that our functional coefficient model is flexible enough to model IBM price durations.

Theta-associated high-frequency oscillations (110–160 Hz) in the hippocampus and neocortex

TORT, A. B. L. ; SCHEFFER-TEIXEIRA, R ; Souza, B.C. ; DRAGUHN, A. ; BRANKACK, J. . Theta-associated high-frequency oscillations (110-160 Hz) in the hippocampus and neocortex. Progress in Neurobiology , v. 100, p. 1-14, 2013.

Prevalence of strabismus among students in Natal-RN - Brazil

To estimate the prevalence of strabismus in Natal, Brazil, among elementary and high school students of the public and private educational systems, in addition to detecting etiological factors. Methods: 1024 students were randomly selected and submitted to a questionnaire and a complete ophthalmologic examination, by professors and resident physicians in Ophthalmology at the Federal University of Rio Grande do Norte. Results: Of 1024 students, 1015 were examined; 29 were found to have strabismus (2.9%), 20 of whom had manifest exotropia (2%), 2 had intermittent exotropia (0.2%), 6 had esotropia (0.6%) and 1 had V anisotropies (0.1%). Conclusions: The strabismus prevalence of the student population of Natal falls within the range of the worldwide population. There was ocular lesion in only one student (retinochoroiditis scar on the posterior pole in both eyes) related to strabismus

Variação temporal da Comunidade de macroinvertebrados bentônicos em um riacho intermitente do semiárido brasileiro

In Brazilian semiarid region, the majority of water bodies are temporary and the biodiversity in these ecosystems is poorly known. The goal of this study was to describe the temporal variation of benthic macroinvertebrates in an intermittent stream in the Brazilian semiarid region. From March to July of 2009, surveys of benthic macroinvertebrates and water physiochemical parameters were done in a first order stream located at Piranhas-Açu River basin. 25 macroinvertebrates families were found, 21 belonging to Insecta class. The chironomids were the most abundant group during all study period and were represented by 19 genus. The largest densities and taxonomic richness were seen in the drying phase of the stream while the smallest values were found in the period with the heaviest rainfalls ( wet phase ). Only the families Chironomidae and Ceratopogonidae were found during all study period, suggesting that these groups have better adaptations to support floods and droughts. Furthermore, these two groups seemed to be pioneering in this stream. Among the chironomids, Paratendipes dominated the period of floods while Tanytarsus were more abundant in the drying phase . This study showed that hydrological fluctuation is the main force influencing the macroinvertebrate community in this stream, therefore, efforts seeking the conservation and management of Brazilian semiarid water bodies should consider this high natural variability in flow regime

Atividade antimalárica de plantas medicinais da biorregião do Araripe-CE em modelo murino - Plasmodium berghei

Malaria, also popularly known as maleita , intermittent fever, paludism, impaludism, third fever or fourth fever, is an acute infectious febrile disease, which, in human beings, is caused by four species: Plasmodium falciparum, P. vivax, P. malariae and P. ovale. Malaria, one of the main infectious diseases in the world, is the most important parasitoses, with 250 million annual cases and more than 1 million deaths per year, mainly in children younger than live years of age. The prophylactic and therapeutic arsenal against malaria is quite restricted, since all the antimalarials currently in use have some limitation. Many plant species belonging to several families have been tested in vivo, using the murine experimental model Plasmodium berghei or in vitro against P. falciparum, and this search has been directed toward plants with antithermal, antimalarial or antiinflammatory properties used in popular Brazilian bolk medicine. Studies assessing the biological activity of medicinal plant essential oils have revealed activities of interest, such as insecticidal, spasmolytic and antiplasmodic action. It has also been scientifically established that around 60% of essential oils have antifungal properties and that 35% exhibit antibacterial properties. In our investigation, essential oils were obtained from the species Vanillosmopsis arborea, Lippia sidoides and Croton zethneri which are found in the bioregion of Araripe-Ceará. The chemical composition of these essential oils was partially characterized and the presence of monoterpenes and sesquiterpenes. The acute toxicity of these oils was assessed in healthy mice at different doses applied on a single day and on four consecutive days, and in vitro cytotoxicity in HeLa and Raw cell lines was determined at different concentrations. The in vivo tests obtained lethal dose values of 7,1 mg/Kg (doses administered on a single day) and 1,8 mg/Kg (doses administered over four days) for 50% of the animals. In the in vitro tests, the inhibitory concentration for 50% of cell growth in Hela cell lines was 588 μg/mL (essential oil from C. zethneri after 48 h), from 340-555 μg/mL (essential oil from L. sidoides, after 24 and 48 h). The essential oil from V. arborea showed no cytotoxicity and none of the essential oils were cytotoxic in Raw cell lines. These data suggest a moderate toxicity in the essential XVIII oils under study, a finding that does not impede their testing in in vivo antimalarial assays. Was shown the antimalarial activity of the essential oils in mice infected with P. berghei was assessed. The three species showed antimalarial activity from 36%-57% for the essential oil from the stem of V. arborea; from 32%-82% for the essential oil from the leaves of L. sidoides and from 40%-70% of reduction for the essential oil from the leaves of C. zethneri. This is the first study showing evidence of antimalarial activity with these species from northeast Brazil. Further studies to isolate the active ingredients of these oils are needed to determine if a single active ingredient accounts for the antimalarial activity or if a complex integration of all the compounds present occurs, a situation reflected in their biological activity

Enraizamento de estacas de Caesalpinia echinata Lam. em hidroponia

This study aimed to determine the indole-3-butyric acid (IBA) requirement and proper concentration for Caesalpinia echinata rooting in a hydroponic system for plantlet production. The experiment was conducted in a greenhouse of the 'Faculdade de Ciencias Agrarias e Veterinarias', UNESP, in Jaboticabal, São Paulo state. The vegetal material consisted of 160 stem cuttings that were 11 to 12 cm in length with two pairs of leaves, prepared from young seedlings. The cutting bases were treated by slow immersion in 5% ethanol solution containing 0, 100, 200 and 400 mg L-1 of IBA during 14 hours and by fast immersion in 50% ethanol solution containing 0, 1000, 3000 and 5000 mg L-1 of IBA during 5 seconds. The cuttings were maintained in the hydroponic system for 90 days and, for additional 90 days in plastic bags containing substrate (Plantmax (R)) under intermittent mist. After 90 and 180 days of rooting, the percentage of cuttings that survived, the rooting percentage and the number and length of adventious root were evaluated. Cuttings should be treated with IBA at 100 mg L-1 for 14 hours and placed to root in a hydroponic system.