920 resultados para Silva, Antonio José da, 1705-1739


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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

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Living organisms are constantly subjected to the action of free radicals, which are one of the causes of oxidation reactions, because they have on free electron, what makes it very reactive. They are products of organism reactions or they are produced by exogenous factors, such as tobacco. Fatty acids are the most vulnerable target, and may suffer lipid peroxidation, what affects the cell structure. Cardiovascular diseases, cancer and diseases of aging are occurrence of these reactions in the organism related. The aliments are also subjected to suffer oxidation reactions, what make them unfit for consumption and decreasing the useful life. Synthetics antioxidants are used as aliments preservatives, but they present some toxicity for the organism. Studies for the utilization of natural antioxidants have gained more importance in recent decades, due to the conservation potential and low toxicity. Phenolics compounds are largely present at the vegetable kingdom and they present high antioxidant potential due to the neutralization and kidnapping of free radicals capacity. These compounds are used by the industry at the aliments conservation, specially the phenolics acids. The consumption of aliments rich in phenolic compounds, such as teas, wines and fruits are low incidence of degenerative diseases related. This study consists in a bibliographic revision that covers these compounds importance in diet and at the food conservation, and the methodologies and difficulties in the extraction process due to variety of molecules of this group.

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A large amount of external factors that can foster the emergence of free radicals in organisms has created a imminent need for understanding and technologies that enables the search of antioxidant componds and extraction of antioxidants from natural sources. These compounds have great potential for kidnapping free radicals which are highly harmful to organisms, being the principal responsible for the decrease in the shelf life of foods, and aging. These free radicals are also related to diseases such as AIDS, arthritis, diabetes, heart disease and others. Fruits and vegetables are true mines of compounds with antioxidant potential, its vitamins and phenolic compounds present an essential role in the nutrition of living beings acting as a defense against degradation of lipids and proteins, which indicates the importance of a diet rich in these nutrients, given that part of the antioxidant defenses of the body comes from the diet. This revision study aims to put in evidence the indispensable role of antioxidants in the survival of organisms.

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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The aim of the present study was to evaluate the efficacy of peroxidase immobilized on corncob powder for the discoloration of dye. Peroxidase was extracted from soybean seed coat, followed by amination of the surface of the tertiary structure. The aminated peroxidase was immobilized on highly activated corncob powder and employed for the discoloration of bromophenol blue. Amination was performed with 10 or 50 mmol.L-1 carbodiimide and 1 mol.L-1 ethylenediamine. The amount of protein in the extract was 0.235 ± 0.011 mg.mL-1 and specific peroxidase activity was 86.06 ± 1.52 µmol min-1 . mg-1, using 1 mmol.L-1 ABTS as substrate. Ten mmol.L-1 and 50 mmol.L-1 aminated peroxidase retained 88 and 100% of the initial activity. Following covalent immobilization on a corncob powder-glyoxyl support, 10 and 50 mmol.L-1 aminated peroxidase retained 74 and 86% of activity, respectively. Derivatives were used for the discoloration of 0.02 mmol.L-1 bromophenol blue solution. After 30 min, 93 and 89% discoloration was achieved with the 10 mmol.L-1 and 50 mmol.L-1 derivatives, respectively. Moreover, these derivatives retained 60% of the catalytic properties when used three times. Peroxidase extracted from soybean seed coat immobilized on a low-cost corncob powder support exhibited improved thermal stability.

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Demographic census from the last decades of the twentieth century began to reveal a tendency concerning the increasing average age of the population. The Brazilian government began introducing ways to manage the effects and consequences of this trend, the most recent being the creation of the "Fundos do Idoso" (Funds for seniors) in the Federal, state and municipal spheres. That law allows transferring federal taxes from common citizens and companies to the funds. This article is specifically written as a critical examination of this governmental initiative towards the problem of an ageing population from the point of view as to how the law has been implemented. With the creation of the funds there will be the enlargement and improvement of services destined for seniors. However, the law mentioned above does not predict an active participation of the seniors in the management of this funds and policies that will come as result.

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Even with several technologies, politics, laws and to knowledge that looks to secure the worthiest conditions of aging, the asylum of olds still marks presence in the contemporaneousness, like a sign of the aging badly succeeded. The present work is the result of practices carried out in institutions of long permanence and, among the effects of the institutionalization of the old age, the most attention was given here to the mechanism of the regression, analyzed through the light of the psychoanalysis.

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The “Estatuto do Idoso”, is a low created from arrangements about seniors citizens contained in the “Constitution of 1988”, assumes a substantial function in the way that the old age is seen and treated in the Brazilian society. This article, a resulted from a research made by the actual researchers, had how analyses’ objective the content of the “Estatuto”, trying to identify images and senses attributed to the old age, with which the senior’s figure have been built, like a differentiated figure. Was possible to apprehend in the “Estatuto” the attempt of differentiating the seniors like citizens of rights, marked by own characteristics who demand protections, services and special benefits. However, a critical examination of the preoccupation, supports, and protection contained in the “Estatuto” allows understanding that the senior finishes being built like fragile, impotent and incompetent being to assuming the management of them lives.

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The active presence of the old ones in the society brings up discussions about the political and social participation in the advanced ages of the life. The senior citizen, like an actor of great relevance in the present time, shows their potential as scriptwriter and protagonist of their own history. However, many spaces constituted vertically, turned for this aim become artificial, abolishing, many times, the spontaneity and potential of these actors. Anyway, the important thing is to open spaces for the different expressions of social participation and that they find their legitimacy and place in the set of the protagonism that attaches life and sense to the world.

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The elders began to be highlighted in the social scene, not only by their numerical growth, but mainly for their redeployment into new social spaces and accelerating its pace of life. This article aims to analyze the specializations and the time built around the aging and trace its repercussions in the subjectivity production of the oldest. Therefore, it was taken as the object of analysis the differentiation of old age in the aging process.

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The personal experience respective is a description of an psychosocial intervention effectuated in the year of 2007 in an institution not government, in the city of Taubaté, with a group of women infected with the virus HIV. We will present in the short form our work, which happened through a therapeutic group, that had as device, the production of new process of subjectivizing with these women in the conduction of them condition of life after the infection with the virus HIV. To determine our actions use the theoretical assumptions of genealogy, of psychology and the theory of institutional operating group with emphasis on aspects of group discussion. During approximately twelve meetings with the denser group work topics such as social violence (inequality of rights, prejudice and stigma), treatment of the condition of serum positive when marked by ambivalence to treatment and the use of defense mechanisms: denial, projection and omnipotence, the weak and intense physical and mental suffering resulting from this process.We end our exhibition while presenting the discursive constructions and, consequently, the multiforms singular potentialities of the group that appeared with our psychosocial interventions.

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This article aims to generate reflections on the current Brazilian educational situation and briefly discuss the changing paradigms of post-modernity that affect it. Today's education will be discussed and questioned from the mold of traditional education institution (postulated analyzed and criticized by Paulo Freire and still present in our society) and soon to be opposed to the proposal from liberating pedagogy (teaching theoretical foundations that focus on developing of a social nature of no alienation and contribution to the formation of critical subjects of their own destiny, comes in trying to transform the current education, reinforced by the individualistic and consumerist bonds in a democratic education (teachers and students in a relationship horizontal) facing the current questions of social values.

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This article aims to portray a survey in order to see whether the established in the Practical Guide Caregiver program (Ministry of Health, established in 2008 to improve the care for the elderly), are also affecting the nursing homes of smaller towns, with reference to a city in São Paulo State, with approximately 100,000 inhabitants located in western Sao Paulo State.