764 resultados para Race equity


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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Objective. To evaluate the potential effects of race on clinical characteristics, extent of disease, and response to chemotherapy in women with postmolar low-risk gestational trophoblastic neoplasia (GTN).Methods. This non-concurrent cohort study was undertaken including patients with FIGO-defined postmolar low-risk GTN treated with comparable doses and schedules of chemotherapy at the New England Trophoblastic Disease Center (NETDC) between 1973 and 2012. Racial groups investigated included whites, African American and Asians. Information on patient characteristics and response to chemotherapy (need for second line chemotherapy, reason for changing to an alternative chemotherapy, number of cycles/regimens, need for combination chemotherapy, and time to hCG remission) was obtained.Results. Of 316 women, 274 (86.7%) were white, 19 (6%) African American, and 23 (7.3%) Asian. African Americans were significantly younger than white and Asian women (p = 0.008). Disease presentation, and extent of disease, including antecedent molar histology, median time to persistence, median hCG level at persistence, rate of D&C at persistence, presence of metastatic disease, and FIGO stage and risk score were similar among races. Need for second line chemotherapy (p = 0.023), and median number of regimens (p = 0.035) were greater in Asian women than in other races.Conclusions. Low-risk GTN was more aggressive in Asian women, who were significantly more likely to need second line chemotherapy and a higher number of chemotherapy regimens to achieve complete remission than women of African American and Asian descent. Further studies involving racial differences related to clinical, biological and environmental characteristics are needed. (C) 2015 Published by Elsevier Inc.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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Suppliers of water and energy are frequently natural monopolies, with their pricing regulated by governmental agencies. Pricing schemes are evaluated by the efficiency of the resource allocation they lead to, the capacity of the utilities to capture their costs and the distributional effects of the policies, in particular, impacts on the poor. One pricing approach has been average cost pricing, which guarantees cost recovery and allows utilities to provide their product at relatively low prices. However, average cost pricing leads to economically inefficient consumption levels, when sources of water and energy are limited and increasing the supply is costly. An alternative approach is increasing block rates (hereafter, IBR or tiered pricing), where individuals pay a low rate for an initial consumption block and a higher rate as they increase use beyond that block. An example of IBR is shown in Figure 1 (on next page), which shows a rate structure for residential water use. With the rates in Figure 1, a household would be charged $0.46 and $0.71 per hundred gallons for consumption below and above 21,000 gallons per month, respectively.

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Cooperatives differ from other businesses in that they are owned by their patrons and net margins are distributed to patrons on the basis of use instead of capital investment. For financing, cooperatives often rely on allocated equities from retained patronage refunds. Retained patronage refunds are noncash allocations of net margins reinvested in a cooperative by patrons. Under an ideal program of equity formation, equity is held by patrons in proportion to patronage. Each patron’s share of financing the cooperative is equal to the share of benefits received. Equities of former patrons are retired as active patrons take on more of the responsibility of financing the organization.

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Using theoretical applications, the authors present an overview of theories that highlight approaches for teaching culturally sensitive content, personal experiences as educator and colleague in a predominantly white college campus and strategies for addressing culturally insensitive experiences in and outside the classroom. Presenters focus on the recruitment and retention of people of color and stress the need for today's predominantly white institutions to become more knowledgeable, tolerant and sensitive about their environments in an effort to make them more accepting.

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In this paper the precautionary principle is reviewed alongside the process of international implementation. Adoption of the precautionary principle is advocated to deal with energy choices as a mechanism to account for potential climate change impacts, notwithstanding the debate on scientific uncertainty on the links between solar activity, greenhouse gas concentration and climate. However, it is also recognized that the widespread application of the precautionary principle to energy choices does not seem to be taking place in the real world. Relevant concrete barriers are identified stemming from the intrinsic logic governing the hegemonic economic system, driving the energy choices by economic surplus and rent generation potential, the existence of social asymmetries inside and among societies as well as by the absence of democratic global governance mechanisms, capable of dealing with climate change issues. Such perception seems to have been reinforced by the outcome of the United Nations Climate Change Conference, held in Copenhagen in December 2009. (c) 2010 Elsevier Ltd. All rights reserved.

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Objectives To analyse the profile of tuberculosis (TB) among Bolivian immigrants, investigate the impact that this population has on the trends of TB and assess equity in access to TB treatment, in the city of Sao Paulo, Brazil. Methods Descriptive study of the epidemiological profile of TB in four city districts with large Bolivian populations, comparing cases among Brazilians and Bolivians, during the 19982008 period was carried out. We used logistic regression to adjust the treatment outcome for potential confounders. Results We identified 2056 new TB cases: 65.7% in Brazilians, 32.1% in Bolivians and 2.2% among other nationalities. Although TB incidence remained stable (high) over the study period, the annual proportion of cases among Bolivians increased from 15.0% to 53.0%. In comparison with the Brazilians, the Bolivians were younger (median age, 24 vs. 40 years; P < 0.0001) and presented a lower unemployment rate (3.1%vs. 11.6%; P < 0.0001), a lower rate of HIV co-infection (1.5%vs. 28.5%; P < 0.001), a higher proportion of individuals receiving supervised treatment (81.5%vs. 62.0%; P < 0.0001) and a higher proportion of cures (71.6%vs. 63.2%; P < 0.0001). After having been adjusted for potential confounder, cure after treatment was not associated with nationality. Conclusions Bolivian immigrants influenced the incidence but not the trends of TB among Brazilians in the study area. We found no significant differences between Bolivians and Brazilians regarding healthcare access or treatment outcome. Guaranteed universal health care access for all, including undocumented individuals, contributes to health equity. Specific intervention strategies are warranted for immigrants with tuberculosis.

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This paper addresses equity in health and health care in Brazil, examining unjust disparities between women and men, and between women from different social strata, with a focus on services for contraception, abortion and pregnancy. In 2010 women's life expectancy was 77.6 years, men's was 69.7 years. Women are two-thirds of public hospital services users and assess their health status less positively than men. The total fertility rate was 1.8 in 2011, and contraceptive prevalence has been high among women at all income levels. The proportion of sterilizations has decreased; lower-income women are more frequently sterilized. Abortions are mostly illegal; women with more money have better access to safe abortions in private clinics. Poorer women generally self-induce abortion with misoprostol, seeking treatment of complications from public clinics. Institutional violence on the part of health professionals is reported by half of women receiving abortion care and a quarter of women during childbirth. Maternity care is virtually universal. The public sector has fewer caesarean sections, fewer low birth weight babies, and more rooming-in, but excessive episiotomies and inductions. Privacy, continuity of care and companionship during birth are more common in the private sector. To achieve equity, the health system must go beyond universal, unregulated access to technology, and move towards safe, effective and transparent care. (C) 2012 Reproductive Health Matters

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Obiettivo del presente lavoro è approntare un’analisi interpretativa dell’operatività dalle Finanziarie regionali, valutarne gli investimenti in capitale di rischio e, in particolare, l’attività di private equity, evidenziando le tendenze in atto, i possibili percorsi evolutivi e le eventuali criticità. La metodologia adottata ha previsto un’articolazione del lavoro lungo due principali direttive: un’analisi di tipo quantitativo sui bilanci di sette esercizi (dal 2002 al 2008), con la finalità di indagare nel dettaglio gli aspetti economici, finanziari e patrimoniali delle Finanziarie regionali attive sul territorio italiano; un’analisi qualitativa basata su un’approfondita rassegna della letteratura internazionale e su interviste mirate ad un campione ampiamente rappresentativo della popolazione osservata. I risultati raggiunti fanno ragionevolmente supporre che sia in atto una profonda ristrutturazione dell’intero sistema delle Finanziarie, che ha visto innanzitutto aumentare il controllo pubblico nella compagine sociale. L’indagine contabile ha permesso di identificare la presenza di due modelli di business ben differenziati: alcune Finanziarie sono orientate ad attività con forte contenuto di intermediazione finanziaria; altre invece sono focalizzate sull’attività di erogazione di servizi sia finanziari di consulenza che reali. L’investimento in capitale di rischio costituisce un attività centrale per le Finanziarie regionali; l’analisi dedicata a tali impieghi ha permesso di individuare, tra esse, alcune realtà tipiche del merchant banking, e più di frequente, del modello di holding. Complessivamente le Finanziarie campionate detengono oltre 400 partecipazioni per un valore che supera 1,7 miliardi di euro; prevalentemente concentrati su una ristretta cerchia di realtà spesso con impatto strategico sul territorio, ovvero strumentali. Segnatamente all’attività di private equity, è stato possibile rilevare come la politica d’investimento delle Finanziarie regionali sia complementare rispetto a quella mediamente espressa dal mercato domestico, anche se restano critici, anche per le Finanziarie, gli investimenti su imprese target con fatturato compreso tra 2 e 10 milioni di euro. Le evidenze circa la struttura dei contratti segnalano una parziale conformità alla best practice individuata dalla letteratura internazionale. In particolare l’uso limitato dello stage financing, la bassa partecipazione alla gestione sono le principali criticità individuate. Infine, della fase di riorganizzazione che pare interessare il sistema delle Finanziarie, si trova conferma nella percezione dei suoi operatori. Interpellati sul futuro dell’attività di investimento in capitale di rischio, hanno fornito indicazioni che consentono di concludere l’esistenza di una polarizzazione delle Finanziarie su due gruppi: da un lato quelle che implementeranno, più o meno, l’attività di private equity, dall’altro quelle che, viceversa, abbandoneranno tale strumento. La normativa sulle società a partecipazione pubblica regionale e la scarsa autonomia nella gestione delle misure affidate sono ritenute, dalle Finanziarie “interessate”, il principale fattore di freno alla loro crescita nel mercato del private equity.

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Abstract (US) Composite material components design and production techniques are discussed in the present graduation paper. In particular, this paper covers the design process and the production process of a carbon-fiber composite material component for a high performance car, more specifically, the Dallara T12 race car. This graduation paper is split in two. After a brief introduction on existing composite materials (their origins and applications), the first part of the present paper covers the main theoretical concepts behind the design of composite material components: particular focus will be given to carbon-fiber composites. The second part of the present paper covers the whole design and production process that the candidate carried out to create the new front mainplane of the Dallara T12 race car. This graduation paper is the result of a six-months-long internship that the candidate conducted as Design Office Trainee inside Dallara Automobili S.p.A. Abstract (ITA) La presente tesi di laurea discute le metodologie progettuali e produttive legate alla realizzazione di un componente in materiale composito. Nello specifico, viene discussa la progettazione e la produzione di un componente in fibra di carbonio destinato ad una vettura da competizione. La vettura in esame è la Dallara T12. Il lavoro è diviso in due parti. Nella prima parte, dopo una breve introduzione sull’origine e le tipologie di materiali compositi esistenti, vengono trattati i concetti teorici fondamentali su cui si basa la progettazione di generici componenti in materiale composito, con particolare riguardo ai materiali in fibra di carbonio. Nella seconda parte viene discusso tutto il processo produttivo che il candidato ha portato a termine per realizzare il nuovo alettone anteriore della Dallara T12. La presente tesi di laurea è il risultato del lavoro di progettazione che il candidato ha svolto presso l’Ufficio Tecnico di Dallara Automobili S.p.A. nel corso di un tirocinio formativo di sei mesi.

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Die Winden-Glasflügelzikade Hyalesthes obsoletus (Cixiidae, Glasflügelzikaden) nutzte in Deutschland ursprünglich die Ackerwinde Convolvulus arvensis als Wirtspflanze, allerdings nahm in den letzten zwei Dekaden die Abundanz auf der Großen Brennnessel Urtica dioica stark zu, zusammen mit der Inzidenz der Schwarzholzkrankheit Bois noir auf Weinreben. Bois noir wird durch ein Phytoplasma verursacht, das durch H. obsoletus von C. arvensis und U. dioica auf Weinreben übertragen wird. Es stellte sich daher die Frage, ob H. obsoletus Wirtsrassen entwickelt hat, die möglicherweise die Bois noir-Epidemiologie beeinflussen. In der vorliegenden Studie wurden folgende Fragestellungen bearbeitet: rn(1) Gibt es in Deutschland und Europa genetisch unterscheidbare Wirtsrassen von H. obsoletus auf den beiden Wirtspflanzen C. arvensis und U. dioica? Es wurden sieben Mikrosatellitenmarker entwickelt und etabliert, um H. obsoletus Populationen aus Deutschland und Europa genetisch zu analysieren. Es zeigte sich eine deutliche Differenzierung zwischen Populationen von beiden Wirtspflanzen in Deutschland, jedoch nicht in den historischen Ursprungsgebieten der deutschen Populationen, in der Schweiz, Italien oder Slovenien.rn(2) Wo sind die deutschen Wirtsrassen von H. obsoletus entstanden? Eine Einwanderung von südlichen, bereits an U. dioica angepassten Individuen stand einer lokalen Wirtsrassenevolution gegenüber. Die engere genetische Verwandtschaft der deutschen Population auf U. dioica zu denen auf C. arvensis, im Vergleich zu den übrigen Populationen auf U. dioica, impliziert einen lokalen Prozess im nördlichen Verbreitungsgebiet. Eine Immigration südlicher Tiere scheint nicht zur Diversifizierung beigetragen zu haben, führte aber möglicherweise einen U. dioica-spezifischen Phytoplasma-Stamm ein. Durch Wirtsrassenevolution entwickelten sich spezifische, vektorbasierte epidemiologische Kreisläufe der Schwarzholzkrankheit Bois noir. rn(3) Welche Präferenzen zeigen die beiden Wirtsrassen von H. obsoletus für die Wirtspflanzen C. arvensis und U. dioica und unterscheiden sich diese? Die Präferenz von H. obsoletus aus beiden deutschen Wirtsrassen in Bezug auf den Geruch der Wirtspflanzen wurde in einem Y-Olfaktometer untersucht, zusätzlich wurden beide Pflanzen direkt zur Wahl gestellt. Bei beiden Untersuchungen zeigte die Population von C. arvensis eine signifikante Präferenz für ihre native Wirtspflanze. Die Population von U. dioica wies dagegen keine Präferenz für den Geruch einer Wirtspflanze auf, bevorzugte im direkten Test jedoch signifikant ihre native Wirtspflanze. Dies weist darauf hin, dass die Anpassung an den „neuen“ Wirt noch nicht vollständig ist.rn

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In the following thesis I present the book The Space Race from South African author Alex Latimer and my translation of some chapters, from English into Italian. Alex Latimer is an illustrator and author based in Cape Town, known mostly for his picture books for children, although his works also appear in magazines and advertisements. The Space Race is his first novel, but it immediately had a good reception amongst readers and critics. The author, his work and his novel The Space Race will be presented in depth in Chapter 1 of the thesis. Then, an overview on the South African fictional production will follow in Chapter 2, focusing mainly on the contemporary trends and trying to understand if and how The Space Race fits. Before presenting my translation and my reflections on the translating process itself, I will outline in Chapter 3 my general approach to the text and its translation, as well as explain the reasons why I chose those specific parts of the book. The original texts and their translations are presented in Chapter 4, preceded by a short introduction to better understand the position of the chapter in the plot and the elements of interests contained in it. A commentary on the translating process will follow in Chapter 5, about problems or just remarks on aspects of interest; also, further elements of complication in the text are described and my solutions presented. The thesis ends with a conclusion on the work done.