990 resultados para Quasi-birth-death


Relevância:

20.00% 20.00%

Publicador:

Resumo:

For some species, hereditary factors have great effects on their population evolution, which can be described by the well-known Volterra model. A model developed is investigated in this article, considering the seasonal variation of the environment, where the diffusive effect of the population is also considered. The main approaches employed here are the upper-lower solution method and the monotone iteration technique. The results show that whether the species dies out or not depends on the relations among the birth rate, the death rate, the competition rate, the diffusivity and the hereditary effects. The evolution of the population may show asymptotic periodicity, provided a certain condition is satisfied for the above factors. (c) 2006 Elsevier Ltd. All rights reserved.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Parkinson's disease is a neurodegenerative disorder of uncertain pathogenesis characterized by a loss of dopaminergic neurons in substantia nigra pars compacta, and can be modeled by the neurotoxin 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP). Oxidative stress may contribute to MPTP- and Parkinson's disease-related neurodegeneration. Fucoidan is a sulfated polysaccharide extracted from brown seaweeds which possesses a wide variety of biological activities including potent antioxidative effects. Here we investigated the effect of fucoidan treatment on locomoter activities of animals, striatal dopamine and its metabolites and survival of nigral dopaminergic neurons in MPTP-induced animal model of Parkinsonism in C57/BL mice in vivo and on the neuronal damage induced by 1-methyl-4-phenylpyridinium (MPP+) in vitro, and to study the possible mechanisms. When administered prior to MPTP, fucoidan reduced behavioral deficits, increased striatal dopamine and its metabolites levels, reduced cell death, and led to a marked increase in tyrosine hydroxylase expression relative to mice treated with MPTP alone. Furthermore, we found that fucoidan inhibited MPTP-induced lipid peroxidation and reduction of antioxidant enzyme activity. In addition, pre-treatment with fucoidan significantly protected against MPP+-induced damage in MN9D cells. Taken together, these findings suggest that fucoidan has protective effect in MPTP-induced neurotoxicity in this model of Parkinson's disease via its antioxidative activity. (C) 2009 Elsevier B.V. All rights reserved.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

本文提出一个不用 Kuhn- Tucker条件而直接搜索严格凸二次规划最优目标点的鲁棒方法 .在搜索过程中 ,目标点沿约束多面体边界上的一条折线移动 .这种移动目标点的思想可以被认为是线性规划单纯形法的自然推广 ,在单纯形法中 ,目标点从一个顶点移到另一个顶点。

Relevância:

20.00% 20.00%

Publicador:

Resumo:

为降低沉积过程的热应力,抑制成形过程中裂缝的产生,研究基板预热对激光金属沉积成形(Laser metal deposition shaping,LMDS)过程热应力的影响具有非常重要的意义。根据有限元分析中的"单元生死"思想,利用APDL(ANSYS parametric design language)编程建立多道多层激光金属沉积成形过程的数值模拟模型,深入探讨基板未预热和预热到400℃时对成形过程热应力的影响。计算结果表明,基板预热到400℃可以显著降低成形过程中试样的热应力变化波动性,试样的Von Mises热应力最大值可降低10%左右,其中x方向热应力最大值可降低8.5%左右,z方向热应力最大值可降低8.1%左右。在与模拟过程相同的条件下,利用自行研制的激光金属沉积成形设备进行了成形试验,成形试验的结果与模拟结果基本吻合。

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Background: ‘Birth Satisfaction’ is a term that encompasses a woman’s evaluation of her birth experience. The term includes factors such as her appraisal of the quality of care she received, a personal assessment of how she coped, and her reconstructions of what happened on that particular day. Her accounts may be accurate or skewed, yet correspond with her reality of how events unfolded. Objective: To evaluate properties of an instrument designed to measure birth satisfaction in a Greek population of postnatal women. Study design: We assessed factor structure, internal consistency, divergent validity and known-groups discriminant validity of the 30-item Greek Birth Satisfaction Scale – Long Form (30-item G-BSS-LF) and its revised version the 10-item Greek-BSS-Revised (10-item-G-BSS-R), using survey data collected in Athens. Participants: A convenience sample of healthy Greek postnatal women (n = 162) aged 22–46 years who had delivered between 34 and 42 weeks’ gestation. Results: The 30-item-G-BSS-LF performed poorly in terms of factor structure. The short-form 10-item-G-BSS-R performed well in terms of measurement replication of the English equivalent version as a multidimensional instrument. The short-form 10-item-G-BSS-R comprises three subscales which measure distinct but correlated domains of: (1) quality of care provision (4 items), (2) women’s personal attributes (2 items), and (3) stress experienced during labour (4 items). Key conclusions: The 10-item-G-BSS-R is a valid and reliable multidimensional psychometric instrument for measuring birth satisfaction in Greek postnatal women.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Grattan, J., Huxley, S., Karaki, L. A., Toland, H., Gilbertson, D., Pyatt, B., Saad, Z. A. (2002). 'Death . . . more desirable than life'? The human skeletal record and toxicological implications of ancient copper mining and smelting in Wadi Faynan, southwestern Jordan. Toxicology and Industrial Health, 18 (6), 297-307.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

R. Zwiggelaar and M.G.F. Wilson, 'Spectral changes in inhomogeneous media; a quasi-optical approach', Int. J. Infrared Millimeter Waves 14 (10), 2253-2259 (1993)

Relevância:

20.00% 20.00%

Publicador:

Resumo:

S.J. Cox and E. Janiaud (2008) On the structure of quasi-two-dimensional foams. Phil. Mag. Letts. 88:693-701 Philosophical Magazine Letters Volume 88, Issue 9-10, 2008 Special Issue: Solid and Liquid Foams. In commemoration of Manuel Amaral Fortes The full text will be available 12 months after publication Sponsorship: We thank K. Brakke for his development and maintenance of the Surface Evolver code, I. Cantat, N. Denkov and F. Graner for their insightful comments on this work, and the participants in the Grenoble Foam Mechanics Workshop (2008) for their suggestions. EJ thanks D. Weaire and S. Hutzler for support, and ESA (MAP AO-99-108:C14914/02/NL/SH, MAP AO-99-075:C14308/00/NL/SH) for funding. SJC thanks the British Council Alliance programme, CNRS and EPSRC (EP/D048397/1, EP/D071127/1) for financial support.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Mavron, Vassili; McDonough, T.P.; Schrikhande, M.S., (2003) 'Quasi -symmetric designs with good blocks and intersection number one', Designs Codes and Cryptography 28(2) pp.147-162 RAE2008

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Projeto de Pós-Graduação/Dissertação apresentado à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de Mestre em Medicina Dentária

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Projeto de Pós-Graduação/Dissertação apresentado à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de Mestre em Medicina Dentária

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Funeral Sermon

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Memorial Sermon.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Funeral sermon

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Memorial Sermon