Directives pratiques de la Société européenne d'hypertension sur la mesure de la pression artérielle à domicile [Practice guidelines of the European Society of Hypertension for home blood pressure measurement].

Self-measurement of blood pressure at home is increasingly used in the diagnostic and therapeutic approach of hypertension. This technique allows multiple measurements of blood pressure away from the clinical setting, making it possible to improve the evaluation of cardiovascular risk. Recently new guidelines on the use of self-measured blood pressure have been made available by the European Society of Hypertension, as summarized in the present paper.

Hepatic glucose sensing is required to preserve β cell glucose competence.

Liver glucose metabolism plays a central role in glucose homeostasis and may also regulate feeding and energy expenditure. Here we assessed the impact of glucose transporter 2 (Glut2) gene inactivation in adult mouse liver (LG2KO mice). Loss of Glut2 suppressed hepatic glucose uptake but not glucose output. In the fasted state, expression of carbohydrate-responsive element-binding protein (ChREBP) and its glycolytic and lipogenic target genes was abnormally elevated. Feeding, energy expenditure, and insulin sensitivity were identical in LG2KO and control mice. Glucose tolerance was initially normal after Glut2 inactivation, but LG2KO mice exhibited progressive impairment of glucose-stimulated insulin secretion even though β cell mass and insulin content remained normal. Liver transcript profiling revealed a coordinated downregulation of cholesterol biosynthesis genes in LG2KO mice that was associated with reduced hepatic cholesterol in fasted mice and reduced bile acids (BAs) in feces, with a similar trend in plasma. We showed that chronic BAs or farnesoid X receptor (FXR) agonist treatment of primary islets increases glucose-stimulated insulin secretion, an effect not seen in islets from Fxr-/- mice. Collectively, our data show that glucose sensing by the liver controls β cell glucose competence and suggest BAs as a potential mechanistic link.

Les Tropes de Dumarsais ([Reprod.]) / avec un commentaire raisonné par M. [Pierre] Fontanier,...

Collection : Archives de la linguistique française ; 132

Des principes de l'architecture, de la sculpture, de la peinture, et des autres arts qui en dépendent : avec un Dictionnaire des termes propres à chacun de ces arts (Ed. sur microfiche) / [Félibien]

Collection : Archives de la linguistique française ; 151

Principes généraux et raisonnés de la grammaire françoise : par demandes et par réponses... ([Reprod.]) / [Restaut]

Collection : Archives de la linguistique française ; 345

La comparaison de la langue et de la poësie françoise, avec la grecque et la latine... ; Et Les amours de Protée et de Physis... ([Reprod.]) / par le sieur Desmarests,...

Collection : Archives de la linguistique française ; 112

La deffense du poëme heroïque : avec quelques remarques sur les oeuvres satyriques du sieur D*** dialogues en vers et en prose ; [précédé de Esther : poëme heroïque composé et dedié au roy] ([Reprod.]) / [par le sieur de Boisval]

Collection : Archives de la linguistique française ; 113

Des Tropes ou Des diferens sens dans lesquels on peut prendre un mème mot dans une mème langue : ouvrage utile pour l'intelligence des auteurs... ([Reprod.]) / par M. Du Marsais

Collection : Archives de la linguistique française ; 131

Réponse à une critique satyrique intitulée "L'Apotheose du Dictionnaire de l'Academie françoise" ([Reprod.]) / par M. Mallement de Messange...

Collection : Archives de la linguistique française ; 255

Deffense de la langue françoise : pour l'inscription de l'arc de triomphe... ([Reprod.]) / par M. Charpentier,...

Collection : Archives de la linguistique française ; 77

Emerging paradigms and questions on pro-angiogenic bone marrow-derived myelomonocytic cells.

Cancer-related inflammation has emerged in recent years as a major event contributing to tumor angiogenesis, tumor progression and metastasis formation. Bone marrow-derived and inflammatory cells promote tumor angiogenesis by providing endothelial progenitor cells that differentiate into mature endothelial cells, and by secreting pro-angiogenic factors and remodeling the extracellular matrix to stimulate angiogenesis though paracrine mechanisms. Several bone marrow-derived myelonomocytic cells, including monocytes and macrophages, have been identified and characterized by several laboratories in recent years. While the central role of these cells in promoting tumor angiogenesis, tumor progression and metastasis is nowadays well established, many questions remain open and new ones are emerging. These include the relationship between their phenotype and function, the mechanisms of pro-angiogenic programming, their contribution to resistance to anti-angiogenic treatments and to metastasis and their potential clinical use as biomarkers of angiogenesis and anti-angiogenic therapies. Here, we will review phenotypical and functional aspects of bone marrow-derived myelonomocytic cells and discuss some of the current outstanding questions.

Logique et principes de grammaire ([Reprod.]) / par M. Du Marsais...

Collection : Archives de la linguistique française ; 130

L'apothéose du "Dictionnaire de l'Académie" et son expulsion de la région céleste : ouvrage contenant cinquante remarques critiques sur ce dictionnaire, auxquelles on en a joint cinquante autres sur divers célèbres auteurs ([Reprod.])

Collection : Archives de la linguistique française ; 80