Alte Stadt-Augsburger, Nürnberger und Münchener Juden-Ordnungen

Karl Schaefer

Alte Stadt-Augsburger, Nürnberger und Münchener Juden-Ordnungen

Karl Schaefer

Alte Stadt-Augsburger, Nürnberger und Münchener Juden-Ordnungen

Karl Schaefer

Fragm. germ. IV 21 - Privileg für Valentin Geißler, Buchdrucker in Nürnberg, zum Druck der Nürnberger Erneuerten Reformation; Preßburg 5. November 1563. Abschrift

Vorbesitzer: Georg Kloß

Ein schön new Lied, Von der Büchenklingen im Nürnberger Wald : Im Thon: Gar lustig ist spazieren gahn

In Fraktur

Les Israélites de la Tunisie : leur condition civile et politique

par Jacques Chalom. Préface de Maurice Colin

Die Nürnberger Puppe : komische Oper in 1 Act

Musik von A. Adam. [Text] von Leuven und A. Beauplan. Dt. von Ernst Pasqué

Casement's report on the condition of the Congo state territory

Roger Casement

Frankfurt, Nürnberger Hof

R. Anheisser fec.

Ausst. 213 - Allianzwappen der Nürnberger Familien Scheurl und Geuder

Vorbesitzer: Heinrich Anton Cornill-d'Orville

Ausst. 214 - Allianzwappen der Nürnberger Familien Scheurl und Geuder

Vorbesitzer: Heinrich Anton Cornill-d'Orville

Statistical Methods for Differential Expressions of Genes Detected in Multiple-Condition Experiment of Microarray

Most studies of differential gene-expressions have been conducted between two given conditions. The two-condition experimental (TCE) approach is simple in that all genes detected display a common differential expression pattern responsive to a common two-condition difference. Therefore, the genes that are differentially expressed under the other conditions other than the given two conditions are undetectable with the TCE approach. In order to address the problem, we propose a new approach called multiple-condition experiment (MCE) without replication and develop corresponding statistical methods including inference of pairs of conditions for genes, new t-statistics, and a generalized multiple-testing method for any multiple-testing procedure via a control parameter C. We applied these statistical methods to analyze our real MCE data from breast cancer cell lines and found that 85 percent of gene-expression variations were caused by genotypic effects and genotype-ANAX1 overexpression interactions, which agrees well with our expected results. We also applied our methods to the adenoma dataset of Notterman et al. and identified 93 differentially expressed genes that could not be found in TCE. The MCE approach is a conceptual breakthrough in many aspects: (a) many conditions of interests can be conducted simultaneously; (b) study of association between differential expressions of genes and conditions becomes easy; (c) it can provide more precise information for molecular classification and diagnosis of tumors; (d) it can save lot of experimental resources and time for investigators.^

(Table 1) Body condition and plasma POP concentrations of glaucous gulls from Bjørnøya, Svalbard archipelago

Behavioural field observations are increasingly being used in ecotoxicological research to identify potential adverse effects of exposure to persistent organic pollutants (POPs). We investigated thermal conditions inside the nest and parental behaviour of glaucous gulls, Larus hyperboreus, breeding in the Norwegian Arctic in relation to the concentrations of major classes of POPs (organochlorines, brominated flame retardants and metabolically derived products) accumulated in their blood. Most notably, nest temperature was negatively correlated with the concentrations of the sum of DDT, sum of PCB and several quantitatively minor POP classes within the incubating parent. To investigate the relationship between incubation ability and parental POP exposure further, we experimentally increased the costs of incubation by artificially increasing the clutch size from two to four eggs. Clutch enlargement was followed by a decrease in nest temperature, but this drop in temperature was not associated with POP concentrations within the incubating parent. However, males, which had higher POP concentrations and lower white blood cell counts than females, seemed less able to maintain nest temperature. There was virtually no evidence to suggest that the sum of PCB or DDT were associated with changes in the time a bird spent incubating. However, there was some indication that nest site attendance by nonincubating males was negatively related to the sum of DDT, suggesting that nest protection may have been compromised. The results suggest that adverse effects of parental POP exposure may occur through suboptimal thermal conditions for embryo development and possibly increased egg predation risk.

Sediment physicochemical properties condition pollutant association : a multivariate study of polybrominated diphenyl ethers on the Mendoza River irrigation areas

This work is a multidisciplinary environmental study that provides new insights into the relationships between sediment-organic matter characteristics and polybrominated diphenyl ethers (PBDEs) concentration. The aim of the present multivariate study was to correlate factors influencing PBDEs accumulation in sediment by using principal component analysis (PCA). Organic matter studies by Fourier Transform-Infrared spectroscopy and physicochemical analyses (Total Organic Carbon, pH, electrical conductivity) of sediment samples were considered for PCA. Samples were collected from an artificial irrigation network on the Mendoza River irrigation areas. PCA provided a comprehensive analysis of the studied variables, identifying two components that explained 63% of the data variance. Those factors were mainly associated to organic matter degradation degree, which represent a new insight into the relationships between organic matter in sediments and PBDEs fate. In this sense it was possible to determine that not only the content but also the type of organic matter (chemical structure) could be relevant when evaluating PBDEs accumulation and transport in the environment. Typification of organic matter may be a useful tool to predict more feasible areas where PBDE, may accumulate, as well as sediment transportation capability.