Cau Oliveros, Miguel Angel: Cerámica tardorromana de cocina de las Islas Baleares, estudio arqueométrico, BAR International Series 1182, 2003.

La sensació que un té quan acaba de llegir el llibre Cerámica tardorromana de cocina de las Islas Baleares. Estudio arqueométrico, de Miguel Angel Cau Ontiveros, és la d'haver llegit diversos libres en un de sol. No sé si hi ha intencionalitat en aquest fet o simplement és fruit d'una preocupa ció més amplia que l'estrictament proposada pel títol de l'obra. Per una part, el propi estudi arqueometric, on les referencies arqueologiques es prenen d'estudis previs fets per altres autors, a excepció deljaciment de Sa Mesquida (Calvia, Mallorca), amb una finalitat clarament historica, la caracterització d'una serie de ceramiques, totes atribuIble s a l'ambit de la cuina en una epoca concreta, per tal de poder determinar basicament el grau d'autosuficiencia d'uns espais insulars.

Epibulbar osseous choristomaa clinicopathological case series and review of the literature

Background:¦Choristomas are benign, congenital tumours composed of normal tissue in an¦abnormal location. Osseous choristomas represent the rarest form of epibulbar choristomas,¦with now 65 cases reported in the literature. We did a retrospective clinicopathological study¦of all patients with epibulbar osseous choristoma observed at our institution since 1982 and¦updated the last review of the literature.¦History and Signs:¦Three Caucasian male patients, aged between 3 months and 11 years,¦were identified. All osseous choristomas were located under the superotemporal bulbar¦conjunctiva of the right eye.¦Therapy and Outcome:¦All lesions were managed with surgical excision. Histopathology¦revealed the presence of lamellar bone in all cases, one of which was associated with a¦dermolipoma.¦Conclusions:¦We report a small rare case series of 3 epibulbar osseous choristomas and did a¦review of the literature. In one patient, the osteoma was associated with a dermolipoma,¦corresponding to the fourth reported complex choristoma of this type, in an otherwise normal¦eye, in the literature.

Expression of MYC, IgM, As Well As Non-Germinal Centre B-Cell Like Immunophenotype and Positive Immunofish Index Predict a Worse Progression Free Survival and Overall Survival in a Series of 670 De Novo Diffuse Large B-Cell Lymphomas Included in Clinical Trials: A GELA Study of the 2003 Program

Introduction: Diffuse large B-cell lymphomas (DLBCL) represent a heterogeneous disease with variable clinical outcome. Identifying phenotypic biomarkers of tumor cells on paraffin sections that predict different clinical outcome remain an important goal that may also help to better understand the biology of this lymphoma. Differentiating non-germinal centre B-cell-like (non-GCB) from Germinal Centre B-cell-like (GCB) DLBCL according to Hans algorithm has been considered as an important immunohistochemical biomarker with prognostic value among patients treated with R-CHOP although not reproducibly found by all groups. Gene expression studies have also shown that IgM expression might be used as a surrogate for the GCB and ABC subtypes with a strong preferential expression of IgM in ABC DLBCL subtype. ImmunoFISH index based on the differential expression of MUM-1, FOXP1 by immunohistochemistry and on the BCL6 rearrangement by FISH has been previously reported (C Copie-Bergman, J Clin Oncol. 2009;27:5573-9) as prognostic in an homogeneous series of DLBCL treated with R-CHOP. In addition, oncogenic MYC protein overexpression by immunohistochemistry may represent an easy tool to identify the consequences of MYC deregulation in DLBCL. Our aim was to analyse by immunohistochemistry the prognostic relevance of MYC, IgM, GCB/nonGCB subtype and ImmunoFISH index in a large series of de novo DLBCL treated with Rituximab (R)-chemotherapy (anthracyclin based) included in the 2003 program of the Groupe d'Etude des Lymphomes de l'Adulte (GELA) trials. Methods: The 2003 program included patients with de novo CD20+ DLBCL enrolled in 6 different LNH-03 GELA trials (LNH-03-1B, -B, -3B, 39B, -6B, 7B) stratifying patients according to age and age-adjusted IPI. Tumor samples were analyzed by immunohistochemistry using CD10, BCL6, MUM1, FOXP1 (according to Barrans threshold), MYC, IgM antibodies on tissue microarrays and by FISH using BCL6 split signal DNA probes. Considering evaluable Hans score, 670 patients were included in the study with 237 (35.4%) receiving intensive R-ACVBP regimen and 433 (64.6%) R-CHOP/R-mini-CHOP. Results: 304 (45.4%) DLBCL were classified as GCB and 366 (54.6%) as non-GCB according to Hans algorithm. 337/567 cases (59.4%) were positive for the ImmunoFISH index (i.e. two out of the three markers positive: MUM1 protein positive, FOXP1 protein Variable or Strong, BCL6 rearrangement). Immunofish index was preferentially positive in the non-GCB subtype (81.3%) compared to the GCB subtype (31.2%), (p<0.001). IgM was recorded as positive in tumor cells in 351/637 (52.4%) DLBCL cases with a preferential expression in non-GCB 195 (53.3%) vs GCB subtype 100(32.9%), p<0.001). MYC was positive in 170/577 (29.5%) cases with a 40% cut-off and in 44/577 (14.2%) cases with a cut-off of 70%. There was no preferential expression of MYC among GCB or non-GCB subtype (p>0.4) for both cut-offs. Progression-free Survival (PFS) was significantly worse among patients with high IPI score (p<0.0001), IgM positive tumor (p<0.0001), MYC positive tumor with a 40% threshold (p<0.001), ImmunoFISH positive index (p<0.002), non-GCB DLBCL subtype (p<0.0001). Overall Survival (OS) was also significantly worse among patients with high IPI score (p<0.0001), IgM positive tumor (p=0.02), MYC positive tumor with a 40% threshold (p<0.01), ImmunoFISH positive index (p=0.02), non-GCB DLBCL subtype (p<0.0001). All significant parameters were included in a multivariate analysis using Cox Model and in addition to IPI, only the GCB/non-GCB subtype according to Hans algorithm predicted significantly a worse PFS among non-GCB subgroup (HR 1.9 [1.3-2.8] p=0.002) as well as a worse OS (HR 2.0 [1.3-3.2], p=0.003). This strong prognostic value of non-GCB subtyping was confirmed considering only patients treated with R- CHOP for PFS (HR 2.1 [1.4-3.3], p=0.001) and for OS (HR 2.3 [1.3-3.8], p=0.002). Conclusion: Our study on a large series of patients included in trials confirmed the relevance of immunohistochemistry as a useful tool to identify significant prognostic biomarkers for clinical use. We show here that IgM and MYC might be useful prognostic biomarkers. In addition, we confirmed in this series the prognostic value of the ImmunoFISH index. Above all, we fully validated the strong and independent prognostic value of the Hans algorithm, daily used by the pathologists to subtype DLBCL.

Prenatal diagnosis of urinary malformations: results in a series of 93 consecutive cases.

OBJECTIVE: To evaluate the pertinence of prenatal diagnosis in cases of congenital uropathy. STUDY DESIGN: Retrospective evaluation over a period of 6.5 years. METHOD: 93 cases were involved in the comparison of prenatal ultrasonographic diagnosis with neonatal findings, autopsy results, and follow-up data. RESULTS: 33 fetuses had renal parenchymal lesions, 44 had excretory system lesions, and 6 had bladder and/or urethral lesions. Seventy-three pregnancies lead to live births. Eighteen terminations of pregnancy were performed on the parents' request for extremely severe malformations. Two intrauterine deaths were observed, and two infants died in the postnatal period. Prenatal diagnosis was obtained at an average of 27 weeks gestation. Diagnostic concordance was excellent in 82% and partial in 12% of cases with renal parenchymal lesions; the false-positive rate was 6%. For excretory system lesions, concordance was excellent in 87% and partial in 7.4% of cases, with a false-positive rate of 5.6%. Finally, concordance was excellent in 100% of cases of bladder and/or urethral lesions. The overall rate of total concordance was 86%. Partial concordance cases consisted of malformations different from those previously diagnosed, but prenatal diagnosis nevertheless lead to further investigations in the neonatal period and to proper management. The false-positive diagnoses (5.4%) never lead to termination of pregnancy. CONCLUSION: Prenatal diagnosis of congenital uropathy is effective. A third-trimester ultrasonographic examination is necessary to ensure proper neonatal management, considering that the majority of cases are diagnosed at this gestational age.

Inverse metamorphic zonation in very low-grade Tibetan zone series of SE Zanskar and its tectonic consequences (NW India, Himalaya)

The metamorphism of the carbonate rocks of the SE Zanskar Tibetan zone has been studied by `'illite crystallinity'' and calcite-dolomite thermometry. The epizonal Zangla unit overlies the anchizonal Chumik unit. This discontinuous inverse zonation demonstrates a late to post-metamorphic thrust of the first unit over the second. The studied area underwent a complex tectonic history: - The tectonic units were stacked from the NE to the SW, generating recumbent folds, NE dipping thrusts and the regional metamorphism. The compressive movements were active under lower temperature conditions, resulting in late thrusts that disturbed the metamorphic zonation. The discontinuous inverse metamorphic zonation dates from this phase. - A NE vergent backfolding phase occurred at lower temperature conditions. It caused the uplift of more metamorphic levels. - A late extensional phase is revealed by the presence of NE dipping low angle normal faults, and a major high angle fault, the Sarchu fault. The low angle normal faults locally run along earlier thrusts (composite tectonic contacts). Their throw has been sufficient to reset a normal stratigraphic superposition (young layers overlying old ones), but insufficient to erase the inverse metamorphic relationship. However, the combined action of backfolding and normal faulting can locally lessen, or even cancel, the inverse metamorphic superposition. After deduction of the normal fault translation, the vertical component of the original thrust displacement through stratigraphy is 400 m, which is a value far too low to explain the temperature difference between the two units. The horizontal component of displacement is therefore far more important than the vertical one. The regional distribution of metamorphism within the Zangla unit points out to an anchizonal front and an epizonal inner part. This fact is in agreement with nappe tectonics.

Highly diverse T cell recognition of a single Plasmodium berghei peptide presented by a series of mutant H-2Kd molecules.

We have tested 21 independent CTL clones for recognition of a single peptide derived from the Plasmodium berghei circumsporozoite protein in the context of 13 mutants of the murine MHC class I molecule H-2Kd. In this series of Kd mutants, amino acid residues located on the upper surface of the alpha-helices were individually substituted by alanine. Remarkably, most clones displayed individual recognition patterns on the Kd mutants. We had previously found that this series of CTL clones was likewise highly diverse in terms of both TCR primary structure and peptide fine specificity. Our data thus reinforce the concept that multiple T cell epitopes are available on the surface of a single peptide-MHC class I complex for recognition by specific TCR.

Lag-one autocorrelation in short series: Estimation and hypothesis testing

In the first part of the study, nine estimators of the first-order autoregressive parameter are reviewed and a new estimator is proposed. The relationships and discrepancies between the estimators are discussed in order to achieve a clear differentiation. In the second part of the study, the precision in the estimation of autocorrelation is studied. The performance of the ten lag-one autocorrelation estimators is compared in terms of Mean Square Error (combining bias and variance) using data series generated by Monte Carlo simulation. The results show that there is not a single optimal estimator for all conditions, suggesting that the estimator ought to be chosen according to sample size and to the information available of the possible direction of the serial dependence. Additionally, the probability of labelling an actually existing autocorrelation as statistically significant is explored using Monte Carlo sampling. The power estimates obtained are quite similar among the tests associated with the different estimators. These estimates evidence the small probability of detecting autocorrelation in series with less than 20 measurement times.

Uso de los modelos de 'series temporales' como técnicas de análisi s de los diseños conductuales

El propósito de este escrito es plantear la posible alternativa, a nivel metodológico, al diseño experimental clásico. A continuación se analizan las principales propiedades que presentan 1os análisis basados en las series temporales y se hace una descripción del modelo ARIMA (0,0,1) como ejemplo de posible análisis de los diseños de base temporal.

Les competències ètiques en la formació musical dels mestres d'educació infantil a la Universitat de Barcelona: avaluació i propostes curriculars

Podeu consultar el document de les jornades completes a: http://hdl.handle.net/2445/42655

Salsa Brava: nómada en Barcelona. Escenarios y métodos de estudio de un estilo musical y bailable

La salsa brava es un estilo musical que surge en Nueva York a cargo de la diáspora latinoamericana, a finales de los años 1960 y principios de 1970. Contemporáneamente a estos años la salsa viajó a ciudades latinoamericanas y, desde hace una década, su trayecto se hace, relativamente, notorio en Barcelona, entre otras ciudades de Europa. En Barcelona, la salsa brava coexiste con otros estilos salseros y se caracteriza por ser usada, festiva y de forma itinerante, en espacios concebidos para otras músicas o fines. Su nomadismo, también es notable a través del desdoblamiento que experimentan las personas que hacen parte de esta escena, incluida la propia autora de esta investigación. El motivo de este artículo es aproximarse de forma histórica, conceptual y etnográfica a diversos momentos de la trayectoria salsera brava, así como a una de sus estrategias metodológicas o bien al hecho de como una música nómada sugiere un método nómada para su estudio.

Titulats en Mestre d'Educació Musical a la Universitat de Barcelona dels cursos 2005 a 2008: estudi d'inserció laboral.

Aquest estudi pretén esbrinar la coherència de la formació rebuda pels mestres d'educació musical que han estudiat a la UB respecte als requeriments necessaris per a la seva inserció laboral. S'ha dut a terme un estudi descriptiu ex post facto per enquesta que ha donat com a resultats un perfil definit de titulat que indica un alt grau d'inserció laboral i un temps d'espera mínim, principalment a les escoles públiques i mitjançant oposicions o borses d'interins. Aquests mestres estan satisfets de la seva feina, i la motivació per aprendre, la capacitat de treball, la comunicació oral, la vocació, la responsabilitat o les habilitats socials són algunes de les competències professionals que creuen que han estat determinants a l'hora de ser contractats. Per tot això es conclou que les persones que han cursat els estudis de Mestre d'Educació Musical de la UB tenen un alt grau d'inserció i satisfacció laboral, i que la formació inicial coincideix en gran part amb les competències de la professió detectades en aquest estudi.

L'educació musical, la formació dels mestres i l'ensenyament obligatori. Panorama històric

En el presente artículo se traza un recorrido de los distintos avatares que ha sufrido la educación musical en España en la enseñanza obligatoria y en la formación de los maestros, desde la creación de la primera escuela normal de Magisterio hasta nuestros días. El proceso seguido por las reglamentaciones ministeriales y algunas experiencias pedagógico-musicales que se han desarrollado a través de los años y que han culminado con la aplicación de la LOGSE, la creación del maestro especialista en educación musical y la normalización de esta parcela educativa dentro de la enseñanza obligatoria.

Titulats en Mestre d'Educació Musical de la Universitat de Barcelona

Aquest estudi pretén esbrinar la coherència de la formació rebuda pels mestres d'educació musical que han estudiat a la UB respecte als requeriments necessaris per a la seva inserció laboral. S'ha dut a terme un estudi descriptiu ex post facto per enquesta que ha donat com a resultats un perfil definit de titulat que indica un alt grau d'inserció laboral i un temps d'espera mínim, principalment a les escoles públiques i mitjançant oposicions o borses d'interins. Aquests mestres estan satisfets de la seva feina, i la motivació per aprendre, la capacitat de treball, la comunicació oral, la vocació, la responsabilitat o les habilitats socials són algunes de les competències professionals que creuen que han estat determinants a l'hora de ser contractats. Per tot això es conclou que les persones que han cursat els estudis de Mestre d'Educació Musical de la UB tenen un alt grau d'inserció i satisfacció laboral, i que la formació inicial coincideix en gran part amb les competències de la professió detectades en aquest estudi.

Estudi dels models de veu cantada de l'alumnat de mestre en Educació Musical

Desde el año 1992, en que se crea la nueva diplomatura de maestro en Educación Musical, las escuelas y facultades de formación del profesorado empiezan a formar a los especialistas responsables de impartir la educación musical en la escuela primaria. Partiendo de la hipótesis de que el ejemplo de voz cantada que presenta el alumnado de la nueva diplomatura no es el más apropiado para ser imitado por niños y niñas de la escuela primaria, el autor de este artículo nos describe el estudio exploratorio practicado al alumnado que finaliza la diplomatura de maestro en educación musical en la Facultat de Formació del Professorat de la Universitat de Barcelona. Este estudio, que ha contado con dos instrumentos de recogida de la información, una observación y un cuestionario, plantea como objetivo principal detectar las dificultades básicas planteadas por el alumnado, y al mismo tiempo conocer las causas que las originan. Una vez analizados en profundidad los datos y las informaciones recogidas, el autor aporta soluciones encaminadas a resolver las problemáticas, así como a mejorar el ejemplo de voz cantada de los futuros maestros.