A influência do ciclo estral no comportamento das linhagens de ratos congênica SLA16 e isogênica SHR

Several studies use only male rats in their experiments, even with all the evidence of differences between the sexes, not only in the reproductive behavior but also in the development of diseases. This absence of studies using female rats is due in part to the estrous cycle. It is known that one estrous cycle lasts four to 5 days and consists of four phases: proestrus, estrus, metestrus and diestrus. Ramos et al. (1999) identified and mapped a QTL in an F2 population derived from interbreeding of strains of SHR (spontaneously hypertensive rats) and Lewis (LEW) rats and found, on chromosome 4, the first QTL of the world related to anxiety in rats. After several backcrosses between SHR and LEW strains, it was developed a congenic strain called SLA16, to refine the study of this QTL. This QTL corresponds to a large genomic region, approximately 75 million basepairs (Mb), and was first called Ofil1 (inner open field locomotion 1). Currently it is called Anxrr16 (anxiety-related response region 16) according to the rat genome database (RGD). Izidio et al. (2011) suggested that the natural fluctuation of the hormones in the estrous cycle of female rats could influence the effects of this locus on behavior. That is, females in DP (diestrus-proestrus) present the QTL in the same genomic region that males, while females in EM (estrus-metestrus) do not present it. The effects of the estrous cycle in the SLA16 strain and its isogenic control SHR were analyzed on the elevated plus maze (EPM), black and white box and on the open field test (OF). In the open field test, the SLA16 strain had higher central locomotion (F=5.0, p <0.05) and peripheral locomotion (F=12.6, p <0.01) compared to the SHR strain. In the elevated plus maze test, the SLA16 strain had the higher number of entries (F=9.5, p <0.01) and time spent in the open arms (F=10.3, p <0.01) compared to the SHR strain. Finally, in the black and white box test, the SLA16 lineage spent more time ...

Estudo anatômico das regiões selar, seio esfenoidal e porções cavernosas das carótidas internas por meio da ressonância magnética

Pós-graduação em Bases Gerais da Cirurgia - FMB

Modelos dinâmicos simplificados, para verificação do comportamento de rede de satélites amarrados por cabos flexíveis, usando-se o método explícito das diferenças finitas

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Condição periodontal, perda dentária e diferenças socioeconômicas em adultos e idosos brasileiros

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Planejamento estratégico e operacional na pequena empresa: impactos da formalização no desempenho e diferenças setoriais

This article analyzes the results of three different field research, carried out simultaneously in small technology-based sectors, metal-mechanical industry and hotel in the city of São Carlos - SP, with goals, concepts and methods of similar research. The studies were classified as quantitative and descriptive and conducted through a survey of opinion with the main leader of the company. It were considered valid for analyses, the responses of 57 leaders, it were 33 technology-based sector, 13 of the metal-mechanic industry and 11 in the hospitality sector. The main results: the formalization of planning has not led to better performance, considering the indicator growth in sales in the three sectors studied and that the degree of formalization of the planning of the companies in the technologybased sector was higher, while the hospitality sector had a percentage smaller. The dynamic aspect of technology-based sector and stability in the hotel sector in the region studied, leads to assume that the turbulence of the environment is a predominant factor, contradicting the proposal of some authors, in which the formal planning is inappropriate for small companies that operate in environments that change quickly.

Avaliação da preocupação com a forma corporal: um desafio

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Estudo normativo do R-2: teste não verbal de inteligência para crianças

This study presents the standardization of the R-2 Non Verbal Intelligence Test for Children conducted at the city of Assis – SP, Brazil, and compares it with the São Paulo city standardization. The sample was composed by 559 children, between 5 and 11 years old, half of each sex, students from Assis city, randomly selected according to their proportion in private and public schools. Results indicate differences between ages and school types, but not between sexes. Percentile norms were established for the total sample at each age. The comparison of Assis and São Paulo city children reveals significant differences and Assis' results slightly higher. The conclusion is that R-2 Test is appropriate to cognitive assessment of Assis children, suggesting the use of new norms for this region.

P300 in individuals with sensorineural hearing loss

INTRODUCTION: Behavioral and electrophysiological auditory evaluations contribute to the understanding of the auditory system and of the process of intervention. OBJECTIVE: To study P300 in subjects with severe or profound sensorineural hearing loss. METHODS: This was a descriptive cross-sectional prospective study. It included 29 individuals of both genders with severe or profound sensorineural hearing loss without other type of disorders, aged 11 to 42 years; all were assessed by behavioral audiological evaluation and auditory evoked potentials. RESULTS: A recording of the P3 wave was obtained in 17 individuals, with a mean latency of 326.97 ms and mean amplitude of 3.76 V. There were significant differences in latency in relation to age and in amplitude according to degree of hearing loss. There was a statistically significant association of the P300 results with the degrees of hearing loss (p = 0.04), with the predominant auditory communication channels (p < 0.0001), and with time of hearing loss. CONCLUSIONS: P300 can be recorded in individuals with severe and profound congenital sensorineural hearing loss; it may contribute to the understanding of cortical development and is a good predictor of the early intervention outcome.

Territórios, multiterritorialidades e memórias dos povos Guarani e Kaiowá: diferenças geográficas e as lutas pela Des-colonização na Reserva Indígena e nos acampamentos-tekoha - Dourados/MS

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Critérios técnicos e de participação social para a recuperação florestal: quais as diferenças na definição de áreas prioritárias?

The Jararaca River Basin suffers significative environmental impacts caused by inaccurate land use. In Brazil, the areas for permanent preservation are defined and protected by the 2012 Federal Law 12.651. These areas are located in the bank side and other specific places. The objective of this paper was to analyze the results of possible alternatives in function of different procedures used in the proposal elaboration. The methodology used was the elaboration of a priority map for the recovery of these areas using the Geographic Information System with multicriterial analyses and comparing it with the guidelines from the Jararaca River Basin Management Plan. As a result, there were identified differences in the priorities defined by technical issues from the priorities defined by public consultation process.

Diferenças individuais no comportamento forrageiro de Polistes versicolor Olivier, 1872 (Vespidae, Polistinae)

Pós-graduação em Ciências Biológicas (Zoologia) - IBRC

Aquisição de densidade mineral óssea e prática de modalidades esportivas de combate em jovens

Pós-graduação em Ciências da Motricidade - IBRC

Explicação e argumentação na linguagem da criança: diferenças e intersecções em dois estudos de caso

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Estágio supervisionado no curso de pedagogia a distância: aproximações e diferenças do ensino presencial

Pós-graduação em Educação - FCT