996 resultados para Dámaso Alonso
Resumo:
La finalitat d’aquest projecte és l’estudi de la tecnologia fotovoltaica basada en cèl∙lules solars de colorant, adquirint coneixements dels materials que composen els dispositius i del seu funcionament per a la posterior fabricació de cèl∙lules solars de referència, sobre les quals es realitzarà la caracterització de prestacions fotovoltaiques. A partir dels resultats obtinguts amb els dispositius de referència s’investigaran i es desenvoluparan nous electròlits basats en solvents verds i/o líquids iònics.
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Il sottoscritto lavoro e ricerca è risultato di circa tre anni di ricerche presso l’Università autonoma di Barcellona ed altre università europee ed iraniane. Il tema della ricerca s’intitola “La storia del Diritto Privato e l’organizzazione giuridica nell’antica Persia” ed è stato realizzato con la gentile direzione della Professoressa Gete Alonso, cattedratica di Diritto Civile presso l’Università Autonoma di Barcellona. In questo lavoro si è parlato maggiormente di due dinastie principali dell’era antica persiana ovvero la dinastia degli achemenide ed i sassani , ovvero un periodo di tempo tra l’anno 550 a.c. ed il 651 d.c. in qui fu il culmine dell’evoluzione storica e giuridica iraniana nell’antica Persia che va a sostituirsi con l’attacco e l’invasione araba e l’inizio dell’era islamica. Questo studio ci offre una base adatta ad effettuare di un lato uno studio comparato tra un sistema giuridico mediorientale antico con altri sistemi giuridici vigenti al tempo nel mondo come l’antica Babilinia, Grecia e Roma e d'altronde creare una base per confrontare il diritto antico applicato in Persia con il diritto attuale applicato nella Repubblica Islamica dell’Iran e quindi proporre una base di studio comparato nel tempo e tra vari sistemi giuridici antichi. Spero tanto che questa ricerca possa essere utile agli studiosi interessati a conoscere vari sistemi giuridici per poi confrontarli con altri sistemi antichi ed oggigiorno vigenti in modo tale di poter migliorare giorno dopo giorno le idee giuridiche applicabili nei vari sistemi attuali.
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Desenvolupament d'un projecte de base de dades sobre Oracle, utilitzant TDD, iteracions, versionat del codi i refactorització.
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The acquisition of neuroendocrine (NE) characteristics by prostate cancer (PCa) cells is closely related to tumour progression and hormone resistance. The mechanisms by which NE cells influence PCa growth and progression are not fully understood. Macrophage migration inhibitory factor (MIF) is a pro-inflammatory cytokine involved in oncogenic processes, and MIF serum levels correlate with aggressiveness of PCa. Here, we investigated the regulation and the functional consequences of MIF expression during NE transdifferentiation of PCa cells. NE differentiation (NED) of LNCaP cells, initiated either by increasing intracellular levels of cAMP or by culturing cells in an androgen-depleted medium, was associated with markedly increased MIF release. Yet, intracellular MIF protein and mRNA levels and MIF gene promoter activity decreased during NED of LNCaP cells, suggesting that NED favours MIF release despite decreasing MIF synthesis. Adenoviral-mediated forced MIF expression in NE-differentiated LNCaP cells increased cell proliferation without affecting the expression of NE markers. Addition of exogenous recombinant MIF to LNCaP and PC-3 cells stimulated the AKT and ERK1/2 signalling pathways, the expression of genes involved in PCa, as well as proliferation and resistance to paclitaxel and thapsigargin-induced apoptosis. Altogether, these data provide evidence that increased MIF release during NED in PCa may facilitate cancer progression or recurrence, especially following androgen deprivation. Thus, MIF could represent an attractive target for PCa therapy.
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The applicability of the protein phosphatase inhibition assay (PPIA) to the determination of okadaic acid (OA) and its acyl derivatives in shellfish samples has been investigated, using a recombinant PP2A and a commercial one. Mediterranean mussel, wedge clam, Pacific oyster and flat oyster have been chosen as model species. Shellfish matrix loading limits for the PPIA have been established, according to the shellfish species and the enzyme source. A synergistic inhibitory effect has been observed in the presence of OA and shellfish matrix, which has been overcome by the application of a correction factor (0.48). Finally, Mediterranean mussel samples obtained from Rı´a de Arousa during a DSP closure associated to Dinophysis acuminata, determined as positive by the mouse bioassay, have been analysed with the PPIAs. The OA equivalent contents provided by the PPIAs correlate satisfactorily with those obtained by liquid chromatography–tandem mass spectrometry (LC–MS/MS).
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En la lectura dialógica, el significado, la comprensión y el aprendizaje se intensifican a través de las interacciones que establecen personas diferentes en relación con un texto. Este artículo se centra en el desarrollo de la lectura dialógica en las comunidades de aprendizaje,especialmente a través de las tertulias literarias dialógicas con familiares, con profesorado y con alumnado, y de las bibliotecas tutorizadas y otras prácticas de lectura compartida con familiares, con otros y otras agentes de la comunidad. Además, se analizan las transformaciones que se producen tanto personalmente como de manera colectiva y comunitaria.
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The Condemned es un juego de lucha en dos dimensiones desarrollado en Flash CS4 y ActionScript 3. El juego consta de cuatro pantallas, en cada una de ellas el jugador se enfrenta a un enemigo controlado por el ordenador a través de una inteligencia artificial. En la creación de este videojuego se ha pasado por todas las fases de desarrollo: diseño gráfico de personajes y escenarios, programación y control de errores.
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Cet article présente les résultats de la revue systématique: Garcia-Alamino JM, Ward AM, Alonso-Coello P, et al. Self-monitoring and self-management of oral anticoagulation. Cochrane Database of Systematic Reviews 2010, Issue 4. Art. No. : CD003839. DOI: 10.1002/14651858.CD003839.pub2.. PMID: 20393937.
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Aplicació d'escriptori per a gestionar l'entorn d'un artesà. Permet portar el control dels seus articles (composició d'aquestos, magatzems, imatges), els seus esdeveniments (fires exposicions), la gestió financera (compres, vendes albarans, factures), el control de notificacions (emails, pdf's), administració dels contactes, així com l'extracció d'informes (llistat d'articles, llistat vendes), en general, permet portar una gestió integral del món artesà.
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Aplicación web desarrollada en J2EE que permite generar código fuente de aplicaciones web (también basadas en J2EE y que se apoyarán en una base de datos) a todos los niveles (interfaz, lógica de negocio, acceso a datos). Soporta varios sistemas de bases de datos y genera aplicaciones para varios servidores de aplicaciones (con y sin contenedor de EJB), y permite personalizar sus características y comportamiento. Las aplicaciones que genera son completamente funcionales, pudiendo realizar operaciones de búsqueda, creación, modificación y borrado de datos.
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Phototropism, or plant growth in response to unidirectional light, is an adaptive response of crucial importance. Lateral differences in low fluence rates of blue light are detected by phototropin 1 (phot1) in Arabidopsis. Only NONPHOTOTROPIC HYPOCOTYL 3 (NPH3) and root phototropism 2, both belonging to the same family of proteins, have been previously identified as phototropin-interacting signal transducers involved in phototropism. PHYTOCHROME KINASE SUBSTRATE (PKS) 1 and PKS2 are two phytochrome signaling components belonging to a small gene family in Arabidopsis (PKS1-PKS4). The strong enhancement of PKS1 expression by blue light and its light induction in the elongation zone of the hypocotyl prompted us to study the function of this gene family during phototropism. Photobiological experiments show that the PKS proteins are critical for hypocotyl phototropism. Furthermore, PKS1 interacts with phot1 and NPH3 in vivo at the plasma membrane and in vitro, indicating that the PKS proteins may function directly with phot1 and NPH3 to mediate phototropism. The phytochromes are known to influence phototropism but the mechanism involved is still unclear. We show that PKS1 induction by a pulse of blue light is phytochrome A-dependent, suggesting that the PKS proteins may provide a molecular link between these two photoreceptor families.