Kitāb ʻAjāyib al-makhlūqāt wa-gharāyib al-mawjūdāt : manuscript, [circa 1650-1700]

On wonders of creation.

The natural history of Aleppo: containing a description of the city, and the principal natural productions in its neighbourhood : together with an account of the climate, inhabitants, and diseases, particularly of the plague

by Alex. Russell.

Observations sur les maladies des arme'es dans les camps et dans les garnisons : avec un traite sur les substances septiques & anti-septiques ... / par M. Pringle ... ; ouvrage traduit de l'anglois sur la seconde edition ; tome second.

Mode of access: Internet.

Sermo de estructura florum, horum differentia, usuque partium eos constituentium ... et constitutio trium novorum generum plantarum ... /

Mode of access: Internet.

De quatuor signis quae apparent in vnguibus manuum /

Signatures: A-D⁸ E⁴.

Theatri machinarvm erster[-sechster] Theill : in welchem vilerley künstliche Machinae in vnterschidlichen Kupfferstücken zu sehen sindt ... /

Some plates by Andreas Bretschneider. Others by or after Henning Grossen, and some after Heinrich Zeising.

Le Missisipi ou la Louisiane dans l'Amérique septentrionale.

Hand colored.

Le Mississipi ou la Louisiane dans l'Amérique septentrionale.

Hand colored.

Ancient geography, as connected with chronology, and preparatory to the study of ancient history; accompanied with an atlas. Compiled chiefly from D'Anville, Adam, Lavoisne, Malte Brun, and other standard works. To which are added problems on the globes, and rules for the construction of maps. To accompany the modern geography by William C. Woodbridge.

Bound with Woodbridge, W.C. A system of universal geography. Hartford 1835.

Charleston Harbor, South Carolina, 1863 (Raster Image)

This layer is a georeferenced raster image of the historic paper map: Charleston Harbor and its approaches showing the positions of the Rebel-batteries, [by] U.S. Coast Survey. It was published in 1863 by Lith. of J. Bien. Scale 1:30,000. Nautical chart covering Charleston Harbor and a portion of Charleston, South Carolina. The image inside the map neatline is georeferenced to the surface of the earth and fit to the South Carolina State Plane Coordinate System (in Meters) (Fipszone 3900). All map collar and inset information is also available as part of the raster image, including any inset maps, profiles, statistical tables, directories, text, illustrations, or other information associated with the principal map. This map shows features such as roads, railroads, houses, vegetation, drainage, military batteries and fortifications, coastal features (shoals, rocks, channels, floating batteries, etc.) and more. Overprinted to show 1/4-mile concentric circles centered on St. Michaels, Charleston; positions occupied by the Union Army and Navy; "Rebel batteries in possession of National forces [and] batteries still held by the Rebels [on] Sept. 7th 1863." Union positions are based "on the authority of Maj. T.B. Brooks." Relief shown by hachures; depths shown by soundings and shading. This layer is part of a selection of digitally scanned and georeferenced historic maps of the Civil War from the Harvard Map Collection. Many items from this selection are from a collection of maps deposited by the Military Order of the Loyal Legion of the United States Commandery of the State of Massachusetts (MOLLUS) in the Harvard Map Collection in 1938. These maps typically portray both natural and manmade features, in particular showing places of military importance. The selection represents a range of regions, originators, ground condition dates, scales, and purposes.

The silk culture in the United States; embracing complete accounts of the latest and most approved modes of hatching, rearing and feeding the silk-worm, managing a cocoonery, reeling, spinning, and manufacturing the silk, &c. ... With brief historical sketches of the silk business, natural history of the silk-worm, the mulberry, &c. comp. from the most approved and reliable works ... To which is added Blydenburgh's Manual of the silk culture; statistics of silk imports, &c., &c.

"The work ... has been prepared ... with the aid of Mr. I. R. Barbour ... we have ... profited by the article on silk in Dr. Ures ... dictionary of arts and sciences, Mr. Bliss's report on silk ... to the legislature of Ohio, Mr. Colman's report to the Massachusetts legislature, &c.; while we have quoted entire The silk manual of ... Mr. Blydenburgh." Advertisement, p. [3]

Climate change and children’s health : a call for research on what works to protect children

Climate change is affecting and will increasingly influence human health and wellbeing. Children are particularly vulnerable to the impact of climate change. An extensive literature review regarding the impact of climate change on children’s health was conducted in April 2012 by searching electronic databases PubMed, Scopus, ProQuest, ScienceDirect, and Web of Science, as well as relevant websites, such as IPCC and WHO. Climate change affects children’s health through increased air pollution, more weather-related disasters, more frequent and intense heat waves, decreased water quality and quantity, food shortage and greater exposure to toxicants. As a result, children experience greater risk of mental disorders, malnutrition, infectious diseases, allergic diseases and respiratory diseases. Mitigation measures like reducing carbon pollution emissions, and adaptation measures such as early warning systems and post-disaster counseling are strongly needed. Future health research directions should focus on: (1) identifying whether climate change impacts on children will be modified by gender, age and socioeconomic status; (2) refining outcome measures of children’s vulnerability to climate change; (3) projecting children’s disease burden under climate change scenarios; (4) exploring children’s disease burden related to climate change in low-income countries, and ; (5) identifying the most cost-effective mitigation and adaptation actions from a children’s health perspective.

Early biomarkers to predict grade of encephalopathy following hypoxic ischaemic injury

The standard early markers for identifying and grading HIE severity, are not sufficient to ensure all children who would benefit from treatment are identified in a timely fashion. The aim of this thesis was to explore potential early biomarkers of HIE. Methods: To achieve this a cohort of infants with perinatal depression was prospectively recruited. All infants had cord blood samples drawn and biobanked, and were assessed with standardised neurological examination, and early continuous multi-channel EEG. Cord samples from a control cohort of healthy infants were used for comparison. Biomarkers studied included; multiple inflammatory proteins using multiplex assay; the metabolomics profile using LC/MS; and the miRNA profile using microarray. Results: Eighty five infants with perinatal depression were recruited. Analysis of inflammatory proteins consisted of exploratory analysis of 37 analytes conducted in a sub-population, followed by validation of all significantly altered analytes in the remaining population. IL-6 and IL-6 differed significantly in infants with a moderate/severely abnormal vs. a normal-mildly abnormal EEG in both cohorts (Exploratory: p=0.016, p=0.005: Validation: p=0.024, p=0.039; respectively). Metabolomic analysis demonstrated a perturbation in 29 metabolites. A Cross- validated Partial Least Square Discriminant Analysis model was developed, which accurately predicted HIE with an AUC of 0.92 (95% CI: 0.84-0.97). Analysis of the miRNA profile found 70 miRNA significantly altered between moderate/severely encephalopathic infants and controls. miRNA target prediction databases identified potential targets for the altered miRNA in pathways involved in cellular metabolism, cell cycle and apoptosis, cell signaling, and the inflammatory cascade. Conclusion: This thesis has demonstrated that the recruitment of a large cohortof asphyxiated infants, with cord blood carefully biobanked, and detailed early neurophysiological and clinical assessment recorded, is feasible. Additionally the results described, provide potential alternate and novel blood based biomarkers for the identification and assessment of HIE.