Atividade antioxidante e anti-inflamatória da hesperidina glicosilada em camundongos submetidos a dieta indutora do estado pró-inflamatório

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Efeito da suplementação de erva mate (Ilex paraguariensis) sobre a capacidade antioxidante total em atletas futebolistas em teste exaustivo em esteira

Introduction: Physical exercise are related to high oxygen consumption, leading to increase on reactive oxygen species (ROS) generation and subsequent oxidative stress. Concomitantly, physical training can improve the antioxidant defense systems, reducing the deleterious activity of ROS. The yerba mate (Ilex paraguariensis) has several bioactive compounds in its composition, providing important antioxidant activity in improving defense systems and reducing the damage caused by ROS. Few studies related to yerba mate with antioxidant effects during exercise. Objective: Evaluate whether the consumption-based drink yerba mate (Ilex paraguariensis) is able to increase the total antioxidant performance (TAP) after an exhaustive test on a treadmill. Methods: The sample counted with 15 female soccers players from Botucatu-SP female soccer team with a mean age of 22.1 ± 4.2 years. For laboratory tests , it was evaluated: triglycerides (TG), total cholesterol (TC) and fractions, glucose and gamma-GT were dosed by dry chemistry (Vitros® System, Johnson & Johnson). LDL-cholesterol was obtained by Friedwald formula. Total antioxidant performance (TAP) was obtained by the method of fluorescence assay for the measurement of plasma. Weight, height and body mass index (IMC) were measured, percentage of body fat was obtained by bioeletrical impedance analysis (Biodinâmics, modelo 450, USA). Arterial blood pressure was checked by auscultatory method and cardiorespiratory fitness was determined by ergoespirometric test (Ramp Protocol). Maltodextrin was supplemented (30 g in 400 ml) 30 minutes after M0 with placebo (400 ml) or mate (5 g in 400 ml of water). Statistical analysis: ANOVA for repeated measures followed by Tukey's test set, p<0.05. Results: There was a decrease in the pH after exhaustive testing for water and tea (p<0.0001), the same was observed for bicarbonate (p<0.0001). In both groups pO₂ increased for ...

Desenvolvimento e avaliação das atividades antioxidante e despigmentante in vitro de emulsões múltiplas a/o/a contendo dipalmitato kójico

Currently, there has been a growing concern for men and women with the appearance of the face and body, driven primarily by aesthetic standards set by the media. For this, the pharmaceutical and cosmetic industries have conducted numerous research projects aiming at the development of formulations that mitigate the aging and some skin disorders such as hipercromies. One of the most frequent pathologies of skin is melasma, a manifestation of hyperpigmentation caused by hipermelanogenesis symmetrical and progressive, caused usually by hormonal irregularities, exposure to sunlight and genetic factors. In addition to sunscreen, the treatment is indicated the use of depigmenting substances, among them the kojic dipalmitate (DK), which is cleaved into kojic acid (5- hydroxy-2-hydroxy-methyl-4H-piran-4-one) by esterase after absorption by the skin cells. The kojic acid inhibits the action of tyrosinase as a chelator of ions and promotes the reduction of eumelanin and its precursor monomer. To promote a controlled release and improve the stability of the system, the DK can be incorporated into multiple emulsions, that is, complex systems composed of two emulsifications, where the two types of emulsions (W/O and O/W or O/W and W/O) exist simultaneously, forming emulsions of type W/O/W or O/W/O. This work aimed to incorporate the DK in emulsion W/O/W, physical-chemical systems obtained and to evaluate the antioxidant and depigmenting action in vitro of the developed formulations. The physico-chemical characterization was performed by microscopic analysis, quantification and size distribution, determination of pH, conductivity, zeta potential and bioadhesive test of the formulations. The droplet size in accordance with the use of light microscopy and dynamic light scattering is approximately 1μm. The pH, electrical conductivity and bioadhesion have not changed with the addition... (Complete abstract click electronic access below)

Adaptação de jogos eletrônicos para aulas de Educação Física

O ambiente virtual está cada vez mais presente na vida do ser humano e, por este motivo, não se pode negligenciar a perspectiva de que os jogos eletrônicos possam ser encampados no contexto das aulas de Educação Física, com as devidas adaptações, proporcionando novas práticas, as quais sejam atraentes, no sentido de ampliar as perspectivas de adesão ao movimento e minimizar as condições do sedentarismo. Desta forma, este trabalho, de natureza qualitativa, teve como objetivo propor a adaptação de alguns jogos eletrônicos, os quais puderam ser aplicados corporalmente, como novas possibilidades de atividades a serem vivenciadas em aulas de Educação Física, bem como, investigar os níveis de estado de ânimo e de satisfação dos alunos frente às aulas que utilizaram esses jogos eletrônicos adaptados. O estudo foi desenvolvido por intermédio da união de pesquisas bibliográfica e exploratória. Para tanto, fizeram parte deste estudo uma amostra intencional, composta por 60 alunos, de ambos os sexos, compreendendo a faixa etária de 10 a 15 anos, pertencentes a uma escola da rede oficial de ensino da cidade de Rio Claro/SP, selecionada por conveniência, a qual participou de uma aula, ministrada pela pesquisadora, composta por três jogos eletrônicos adaptados. Para se verificar o estado de ânimo dos alunos, foi aplicada a Lista de Estados de Ânimo Reduzida e Ilustrada (LEA-RI), desenvolvida por Volp (2000), antes e após as aulas. Foi aplicado, ainda, um questionário contendo perguntas abertas, com o intuito de se verificar o nível de satisfação dos alunos em relação aos jogos eletrônicos adaptados. Os dados foram analisados por meio da Técnica de Análise de Conteúdo Temático. Os resultados apontaram que os jogos eletrônicos, vinculados à aula de Educação Física, influenciam positivamente na motivação dos alunos... (Resumo completo, clicar acesso eletrônico abaixo)

Incorporação do trans-resveratrol em sistemas nanoestruturados: avaliação das ações antioxidante e despigmentante in vitro

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Proposta de um dispositivo para adaptação em uma cama hospitalar para ajuste de altura

In hospitals, health professionals may face different situations and problems. By following them, it is remarkable that one of the difficulties is related to the support provided by the facilities to carry out their work. This also affects the quality of treatment offered to patients. One of the points of improvement that could be studied is hospital beds. The Fawler's simplest hospital bed type, used in most Brazilian public hospitals, is designed with an ergonomic average height that offers a default position for analysis and treatment of patients. There is no possibility of adjusting the height of those beds, and hence there is a limitation in this regard since that height is fixed, but the physical structures of the workers and patients may vary widely and there may be a conflict when there are people too large or small involved in this process. Beyond that, studies by experts show that beds with height adjustment decreases the muscular effort and improve the movement quality of the spine of nursing staff, reducing the force on certain vertebrae and also the ergonomic risk. Of course, patient comfort is also affected accordingly. As the beds made with height adjustment are very expensive, this study aims to design a device to adapt the not adjustable beds. The project must be viable from an economic and mechanic standpoint, being able to adapt both old and new simplest Fawler hospital bed models, since their dimensions are similar. The final result shows that it is possible to adapt such beds using the designed concept at a viable cost. Furthermore, this concept could be applied in other bed types or objects that have hollow feet

Desenvolvimento de aplicativo de análise técnica e econômica para adaptação de uma roda d’água acionada por cima para geração de energia elétrica no meio rural

The steel type AISI 4130 (ultra-high strength steel) is an alloy of low carbon and its main alloying elements are chromium and molybdenum, which improves the toughness of the weld metal. It has numerous applications, especially where the need for high mechanical strength. It is widely used in equipment used by the aviation industry, such as cradle-tomotor, and this is the motivation for this study. Cots are of fundamental importance, because the engine supports and maintains balance in the fixed landing gear. This equipment is subjected to intense loading cycles, whose fractures caused by fatigue are constantly observed. Will be determined the effects caused by re-welding the structure of aeronautical equipment, and will also study the microstructure of the metal without welding. The studies will be done on materials used in aircraft, which was given to study. The results provide knowledge of microstructure to evaluate any type of fracture that maybe caused by fatigue. Fatigue is a major cause of aircraft accidents and incidents occurred, which makes the study of the microstructure of the metal, weld and re-solder the knowledge essential to the life of the material. The prevention and control of the process of fatigue in aircraft are critical, since the components are subjected to greater responsibility cyclic loading

Avaliação da estabilidade e atividade antioxidante da Vitamina C em preparações cosméticas

Não possui

Avaliação da atividade antioxidante, fotoprotetora e antiglicação dos extratos de folhas e frutos de espécies da família Annonaceae

Pós-graduação em Biociências - FCLAS

Avaliação do potencial antioxidante, citotóxico e fotoprotetor de extratos de Hymenaea courbaril L. e Hymenaea stigonocarpa Mart. ex Hayne

Pós-graduação em Biociências - FCLAS

Determinação de compostos bioativos e capacidade antioxidante em sucos frescos e pasteurizados de laranja

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Efeitos da ingestão aguda do suco de laranja na resposta glicêmica e insulínica, níveis séricos de leptina e adiponectina, consumo energético e atividade antioxidante

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Congelação de células espermáticas provenientes de epidídimo de gatos domésticos contendo antioxidante no meio diluidor

Pós-graduação em Medicina Veterinária - FCAV

Fipronil e produtos de degradação: adaptação de método analítico e caracterização de amostras de água, solo e sedimento da Bacia Hidrográfica do Turvo/Grande

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Sementes de pitanga (Eugenia uniflora L.): potencial antioxidante e perfil de ácidos graxos

The purpose of the present investigation was to characterize the pitanga seeds on centesimal composition, and also to evaluate its antioxidant potential and fatty acid profile. For obtaining the extract, the dehydrated and ground seeds were treated with ethyl alcohol for 30 minutes, at a proportion of 1:3 of seeds:ethyl alcohol, under continuous agitation at room temperature. Afterwards, the mixture was filtered and the supernatant was placed into a rotoevaporator at 40ºC for determining the extract’s dry matter yield, by direct weighing. According to the results, the seeds of cherry showed high amounts of carbohydrates, and offer relevant content and antioxidant activity of phenolic compounds. In the seed oil, cherry high lighted a higher percentage of unsatured fatty acids, oleic being the main component.