Iowa Lottery Action, vo. 19, No. 5, Feb. 25-March 10, 2013

Iowa Lottery Retailer Newsletter

Iowa Lottery Action Special Ediition, June 25, 2012

Iowa Lottery Retailer Newsletter Special Edition

Iowa Lottery Action, Vol. 18, No. 18, Sept. 12-25, 2011

Iowa Lottery Retailer Newsletter

Iowa Lottery Action, Vol. 18, No. 15, July 25-Aug. 7, 2011

Iowa Lottery Retailer Newsletter

Les llengües en els òrgans centrals de l'Estat espanyol (un balanç de 25 anys de la CE)

L'article de Boix fa un balanç de les llengües en els òrgans centrals de l'Estat espanyol al llarg de 25 anys de la Constitució espanyola. L'article està bastit a partir de dos blocs: el primer és una presentació històrica de la relació entre l'Estat i les llengües, i el segon és una valoració per part del propi autor sobre les necessitats actuals de la política lingüística estatal. En el primer apartat s'aborden els aspectes que segueixen: 1) l'escassa consideració del multilingüisme a Espanya, tal com s'ha fet evident amb diferents fets històrics que s'esmenten. 2) Les divergències en les consideracions de la diversitat lingüística en la política; aquestes consideracions són el liberalisme homogeneitzador (en què la diversitat lingüística es considera equivalent a fragilitat de l'Estat) i el liberalisme comunitarista (on l'estat liberal ha de tenir en compte la promoció de la diversitat cultural i lingüística dels ciutadans). 3) El reconeixement legal de la diversitat lingüística en la transició política i

Friday Facts, April 25, 2014, Vol. 208

Bureau of Nutrition and Health Promotion part of the Iowa Department of Public Health produces of weekly newsletter about the Iowa WIC Program for the State of Iowa citizen.

Iowa Board of Nursing Newsletter, August-September-October 2006, Vol. 25, no. 3

Newsletter produced by the Iowa Board of Nursing for nurses to keep them informed to CE classes, renewals, board meetings, etc. Produced 4 times a year. Also known as Nursing Newsletter.

Iowa Board of Nursing Newsletter, November-December 2006, January 2007, Vol. 25, no. 4

Newsletter produced by the Iowa Board of Nursing for nurses to keep them informed to CE classes, renewals, board meetings, etc. Produced 4 times a year. Also known as Nursing Newsletter.

Activity-dependent phosphorylation of SNAP-25 in hippocampal organotypic cultures.

Synaptosomal-associated protein of 25 kDa (SNAP-25) is thought to play a key role in vesicle exocytosis and in the control of transmitter release. However, the precise mechanisms of action as well as the regulation of SNAP-25 remain unclear. Here we show by immunoprecipitation that activation of protein kinase C (PKC) by phorbol esters results in an increase in SNAP-25 phosphorylation. In addition, immunochemical analysis of two-dimensional sodium dodecyl sulfate-polyacrylamide gel electrophoresis gels shows that SNAP-25 focuses as three or four distinct spots in the expected range of molecular weight and isoelectric point. Changing the phosphorylation level of the protein by incubating the slices in the presence of either a PKC agonist (phorbol 12,13-dibutyrate) or antagonist (chelerythrine) modified the distribution of SNAP-25 among these spots. Phorbol 12,13-dibutyrate increased the intensity of the spots with higher molecular weight and lower isoelectric point, whereas chelerythrine produced the opposite effect. This effect was specific for regulators of PKC, as agonists of other kinases did not produce similar changes. Induction of long-term potentiation, a property involved in learning mechanisms, and production of seizures with a GABA(A) receptor antagonist also increased the intensity of the spots with higher molecular weight and lower isoelectric point. This effect was prevented by the PKC inhibitor chelerythrine. We conclude that SNAP-25 can be phosphorylated in situ by PKC in an activity-dependent manner.

IL-1β Suppresses Innate IL-25 and IL-33 Production and Maintains Helminth Chronicity.

Approximately 2 billion people currently suffer from intestinal helminth infections, which are typically chronic in nature and result in growth retardation, vitamin A deficiency, anemia and poor cognitive function. Such chronicity results from co-evolution between helminths and their mammalian hosts; however, the molecular mechanisms by which these organisms avert immune rejection are not clear. We have found that the natural murine helminth, Heligmosomoides polygyrus bakeri (Hp) elicits the secretion of IL-1β in vivo and in vitro and that this cytokine is critical for shaping a mucosal environment suited to helminth chronicity. Indeed in mice deficient for IL-1β (IL-1β(-/-)), or treated with the soluble IL-1βR antagonist, Anakinra, helminth infection results in enhanced type 2 immunity and accelerated parasite expulsion. IL-1β acts to decrease production of IL-25 and IL-33 at early time points following infection and parasite rejection was determined to require IL-25. Taken together, these data indicate that Hp promotes the release of host-derived IL-1β that suppresses the release of innate cytokines, resulting in suboptimal type 2 immunity and allowing pathogen chronicity.

EPI Update, April 25, 2014

Weekly newsletter for Center For Acute Disease Epidemiology of Iowa Department of Public Health.

20 Native Trees to Plant, January 25, 2010

If you have ever flown in an airplane over Iowa, you would see that our woodlands are scattered along the rivers and streams and areas too steep to farm. You would also see a green carpet of trees within out cities and towns. Did you know the 90% of the over 2.7 million acres of forest in Iowa is owned by over 138,000 different private owners? Or that 30% of the land cover in a typical Iowa community if covered by trees? Trees are vital for the protection of our drinking water supply, critical for wildlife habitat, and help sustain employment of over 7,000 Iowans in the wood products industry. This booklet "20 Native trees to Plant" will help you gain a greater knowledge about Iowa's trees and forests. Learn about and enjoy Iowa's trees. Consider ways that you can improve our environment by planting and caring for Iowa's trees and forests.