995 resultados para neurite óptica
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O trabalho descreve o contexto da hospitalização vivenciado pelo acidentado no trânsito e por seu familiar-acompanhante. Com abordagem qualitativa e norteada pela pesquisa convergente assistencial, a investigação realizou-se em um hospital de emergência em Fortaleza, Ceará, em 2004, com 14 pessoas - sete pacientes com trauma musculoesquelético e sete familiares acompanhantes. Na visão dos participantes, o momento da hospitalização é permeado pela depressão, ansiedade, tristeza, medo, preocupação, desinformação, destrato da equipe de saúde ao paciente e família, sendo exacerbado pelo trauma físico, dificuldades econômicas, sociais e implicações legais. De acordo com o princípio da integralidade, o cuidado ao vitimado no trânsito deve ser ampliado aos familiares, pois esses também sofrem danos quando deparam com morte súbita, traumas graves e seqüelas em pessoas significativas.
Resumo:
Este estudo objetivou analisar o curso Técnico em Enfermagem do PROFAE, sob a perspectiva dos egressos, vislumbrando o reconhecimento dos pontos fortes e as dificuldades decorrentes do desenvolvimento do curso. Estudo descritivo-exploratório de natureza qualitativa, desenvolvido com os egressos da Escola de Saúde Pública do Ceará. Foram realizados dois grupos focais, com 21 egressos, em maio e junho de 2007. Utilizou-se a análise de conteúdo para a compreensão das falas. Evidenciou-se que o curso proporcionou aquisição de conhecimentos, transformando a vida dos participantes, passando a ser agente de mudança no contexto de trabalho. Foram analisados a qualidade do currículo, a metodologia, o material didático disponibilizado pela instituição, bem como a atuação do corpo docente. Como pontos frágeis citaram-se a limitação do campo de estágio, duração do curso e gerenciamento de ajuda de custo. Entende-se que a avaliação representa um aspecto importante para o curso, ensejando o aperfeiçoamento da proposta.
Resumo:
En la primera fase s’interconnectarien a través d’un anell de fibra òptica tres hotels d’una mateixa cadena en l’àrea del 22@ de Barcelona. S’ofereixen els serveis de: intranet, telefonia IP amb interconnexió a la PSTN, videoconferència i internet. Utilitzem VLANs per gestionar la qualitat de servei i la seguretat. El nostre model teòric inclou estimacions de tràfic, comparativa de fabricants, valoració econòmica i diagrama de Gantt d’implantació. A més, ampliem la gamma de serveis amb una xarxa Wimax al 22@ en previsió de futur ús. I augmentem la disponibilitat del servei amb un enllaç ràdio dedicat de backup des d’un dels nodes cap a la torre de Collserola, en la banda dels 18GHz, amb antenes parabòliques. Hem fet càlculs d’atenuació. En la segona i successives fases s’amplia la xarxa de FO a nivell nacional i internacional per a treballar com a operador d’empreses, amb un acurat disseny i selecció dels aparells òptics.
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Os efeitos da globalização da economia, a graduação de Cabo Verde à categoria de país de desenvolvimento médio, a entrada para a OMC, a parceria especial com a União Europeia, são acontecimentos verificados num passado próximo que vieram trazer novas exigências ao país em diversos domínios. A preparação das contas e o relato da informação pode ser considerada uma delas. De facto, o normativo contabilístico existente até então, assente num Plano Oficial de Contabilidade (PNC) aprovado por diploma legislativo datada de 1984 já não respondia a todas as necessidades de informação nos domínios da contabilidade, fiscalidade e financeira. O trabalho assenta sobretudo na adopção do SNCRF – Sistema de Normalização Contabilística e de Relato Financeiro. O objectivo é analisar o processo de adopção pela primeira vez deste sistema e os impactos que esta adopção teve na posição financeira nas empresas. Foi feito um estudo de caso para ilustrar este processo. Descrevemos como foi adoptado o SNCRF, fizemos uma apreciação a essa adopção e sugerimos melhoria que deveria ser introduzidas para que os resultados do processo incorporassem a quase totalidade dos procedimentos instituídos nos diversos documentos normativos e legais. Ao trabalho foi dado uma dimensão prática consubstanciada num estudo de caso que serviu para ilustrar o processo de transição. O estudo foi abordado numa perspectiva apreciativa tendo sido inventariadas as situações que deveriam ser salvaguardas (de acordo com o novo normativo e imperativos legais) no processo de transição / conversão e que não foram feitas. Demonstrou-se ainda (através da análise da posição financeira da entidade), que o processo de adopção implicou algumas alterações na estrutura financeira e no valor do capital próprio. A conclusão que se chegou indica que o processo não terá sido tão linear como se desejaria apesar de em, substancia, os principais requisitos terem sido cumpridos. The effects of globalization of its economy, the upgrading of Cape Verde to the category of medium development country, the entry to WTO, the special partnership with European Union, are recent events that brought new demands to the country in several areas. . Preparation of the accounts and information report are included in these new requirements. In fact, the accounting standards till then in force, based on an Official Chart of Accounts (PNC) in force after a law of 1984, didn’t meet the requirements on accounting, fiscal and financial information. This work is basically on the adoption of the new SNCRF – System of Accounting Standardization and Financial Reporting. Our aim is to review the initial adoption process of such system and the impacts this adoption has caused to the financial position of enterprises. A case study is included to illustrate this process. We describe how the SNCRF was adopted; we made an analysis of this adoption and suggested improvements to be introduced in such way that the results of the process include most of the procedures established by law. A practical dimension was attached to this work, through a case study illustrating the transition process. The study adopted an analytical approach, listing the situations that should have been (according to the new standards and legal prescriptions) but were not prevented during the transition / conversion process. The study shows (by the analysis of the financial statements of the studied entity) that the adoption process implied some changes to the financial structure and to the owners’ equity value). One arrives to the conclusion that the process was not as linear as one would expect, although essentially the main requirements were accomplished.
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El Grup de Visió per Computador i Robòtica (VICOROB) del departament d'Electrònica, Informàtica i Automàtica de la Universitat de Girona investiga en el camp de la robòtica submarina. Al CIRS (Centre d’Investigació en Robòtica Submarina), laboratori que forma part del grup VICOROB, el robot submarí Ictineu és la principal eina utilitzada per a desenvolupar els projectes de recerca. Recentment, el CIRS ha adquirit un nou sistema de sensors d' orientació basat en una unitat inercial i un giroscopi de fibra òptica. Aquest projecte pretén realitzar un estudi d' aquests dispositius i integrar-los al robot Ictineu. D' altra banda, aprofitant les característiques d’aquests sensors giroscopics i les mesures d' un sonar ja integrat al robot, es vol desenvolupar un sistema de localització capaç de determinar la posició del robot en el pla horitzontal de la piscina en temps real
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Es descriu la situació de l'edició òptica a Catalunya a partir de l'anàlisi de la producció editorial apareguda fins ara al mercat. En concret, es fa referència a la publicació de títols per anys, els editors, l'idioma de publicació, i el lloc d'edició, entre altres aspectes. També s'exposen quins són els principals problemes que afecten el sector així com les oportunitats i avantatges que pot comportar per als editors utilitzar els suports òptics.
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Thy-1 is a membrane glycoprotein suggested to stabilize or inhibit growth of neuronal processes. However, its precise function has remained obscure, because its endogenous ligand is unknown. We previously showed that Thy-1 binds directly to α(V)β(3) integrin in trans eliciting responses in astrocytes. Nonetheless, whether α(V)β(3) integrin might also serve as a Thy-1-ligand triggering a neuronal response has not been explored. Thus, utilizing primary neurons and a neuron-derived cell line CAD, Thy-1-mediated effects of α(V)β(3) integrin on growth and retraction of neuronal processes were tested. In astrocyte-neuron co-cultures, endogenous α(V)β(3) integrin restricted neurite outgrowth. Likewise, α(V)β(3)-Fc was sufficient to suppress neurite extension in Thy-1(+), but not in Thy-1(-) CAD cells. In differentiating primary neurons exposed to α(V)β(3)-Fc, fewer and shorter dendrites were detected. This effect was abolished by cleavage of Thy-1 from the neuronal surface using phosphoinositide-specific phospholipase C (PI-PLC). Moreover, α(V)β(3)-Fc also induced retraction of already extended Thy-1(+)-axon-like neurites in differentiated CAD cells as well as of axonal terminals in differentiated primary neurons. Axonal retraction occurred when redistribution and clustering of Thy-1 molecules in the plasma membrane was induced by α(V)β(3) integrin. Binding of α(V)β(3)-Fc was detected in Thy-1 clusters during axon retraction of primary neurons. Moreover, α(V)β(3)-Fc-induced Thy-1 clustering correlated in time and space with redistribution and inactivation of Src kinase. Thus, our data indicates that α(V)β(3) integrin is a ligand for Thy-1 that upon binding not only restricts the growth of neurites, but also induces retraction of already existing processes by inducing Thy-1 clustering. We propose that these events participate in bi-directional astrocyte-neuron communication relevant to axonal repair after neuronal damage.
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Fas apoptosis inhibitory molecule (FAIM) is a protein identified as an antagonist of Fas-induced cell death. We show that FAIM overexpression fails to rescue neurons from trophic factor deprivation, but exerts a marked neurite growth–promoting action in different neuronal systems. Whereas FAIM overexpression greatly enhanced neurite outgrowth from PC12 cells and sympathetic neurons grown with nerve growth factor (NGF), reduction of endogenous FAIM levels by RNAi decreased neurite outgrowth in these cells. FAIM overexpression promoted NF-κB activation, and blocking this activation by using a super-repressor IκBα or by carrying out experiments using cortical neurons from mice that lack the p65 NF-κB subunit prevented FAIM-induced neurite outgrowth. The effect of FAIM on neurite outgrowth was also blocked by inhibition of the Ras–ERK pathway. Finally, we show that FAIM interacts with both Trk and p75 neurotrophin receptor NGF receptors in a ligand-dependent manner. These results reveal a new function of FAIM in promoting neurite outgrowth by a mechanism involving activation of the Ras–ERK pathway and NF-κB.
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El artículo analiza los elementos esenciales del nuevo delito de trata de personas que incorporado al CP mediante la reforma de 2010. Asimismo explora la tipificación de la trata de personas en Derecho comparado, los compromisos internacionales adquiridos por el Estado español acerca de la incriminación de esta conducta y su nivel de cumplimiento con el nuevo delito.
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Wnt factors regulate neural stem cell development and neuronal connectivity. Here we investigated whether Wnt-3a and Wnt-3, expressed in the developing spinal cord, regulate proliferation and the neuronal differentiation of spinal cord neural precursors (SCNP). Wnt-3a promoted a sustained increase of SCNP proliferation, whereas Wnt-3 enhanced SCNP proliferation transiently and increased neurogenesis through β-catenin signaling. Consistent with this, Wnt-3a and Wnt-3 differently regulate the expression of Cyclin-dependent kinase inhibitors. Furthermore, Wnt-3a and Wnt-3 stimulated neurite outgrowth in SCNP-derived neurons through ß-catenin and TCF4-dependent transcription. GSK-3ß inhibitors mimicked Wnt signaling and promoted neurite outgrowth in established cultures. We conclude that Wnt-3a and Wnt-3 signal through the canonical Wnt/β-catenin pathway to regulate different aspects of SCNP development. These findings may be of therapeutic interest for the treatment of neurodegenerative diseases and nerve injury.
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Optical spectroscopy in the 400-1700nm wavelength range was performed on rare earth doped heavy metal fluoride (HMF) glasses. In the present work In-based fluoride glasses with a fixed 2 mol % YbF3 concentration and an ErF3 content ranging from 0 to 8 mol % were investigated. According to the experimental spectroscopic data a dependence in the absorption coefficient, the photoluminescence intensity and in the radiative lifetime could be verified as a function of the ErF3 content. In addition, at liquid nitrogen temperature, light emission corresponding to indirect transitions in the infrared energy range could be easily observed as a consequence of the low phonon frequency characteristic of this class of fluoride glasses. For all the studied compositions, strong upconversion to the green and red light was observed by pumping these Er3+- and Yb3+-doped HMF glasses with 790 and 980nm photon sources.
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The goal of this study was to evaluate the feasibility of direct introduction of clay slurries in an inductively coupled plasma optical emission spectrometer with axial view configuration. Calibration was performed using a certified reference material with a mean particle size of 13 µm (IPT-42) and the analytical curve was applied for quantification of two others reference materials (IPT-28 and IPT-32) and four samples. It was demonstrated that the analytical curve thus obtained was not completely suitable for IPT-28 and samples due to different mineralogical phases determined by X-ray diffraction. After considering this effect, it was possible for most elements to obtain results in agreement with certified values or with values obtained by a conventional technique at a 95% confidence level. It was demonstrated that the ICP-OES with axial view configuration did not present any incompatibility with the direct introduction of a complex inorganic suspension.
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A study is presented of the formation and optical properties of polymeric heterostructures from poly(p-phenylene vinylene) (PPV) and poly(o-methoxyaniline) (POMA) produced via the self-assembly technique. POMA layers were obtained in a non self-limiting process from its emeraldine salt, semiconducting form in HCl solution. Thermal conversion of PPV was performed at low temperatures with the substitution of the counter-ion Cl in the PPV precursor by a long sulfonic chain, the dodecylbenzenesulfonate (DBS) ion. The optical properties of PPV films converted in this way are not affected by POMA, which can be used as transparent electrode of PPV luminescent devices.
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In this work a closed-vessel microwave-assisted acid decomposition procedure for clays was developed. Aluminum, Ca, Fe, K, Mg, Na, Si, and Ti were determined in clay digestates by inductively coupled plasma optical emission spectrometry. The most critical parameter for total decomposition of clays was the composition of the reagent mixture. The applied power and the heating time exerted a less critical influence. Best decomposition conditions were attained using a reagent mixture containing 4 mL aqua regia plus 3 mL HF and the heating program was implemented in 12 min. The accuracy of the results was demonstrated using two standard reference materials and a paired t-test showed a good agreement between determined and certified values at a 95% confidence level.