927 resultados para institutional (re)organization


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En este artículo se analiza el resurgimiento de talleres de costura clandestinos en grandes ciudades del centro y la periferia mundial, para entender los cambios dados en la industria de la moda durante las últimas cuatro décadas y sus consecuencias sobre los trabajadores. Para ello se realizaron dos estudios de caso: uno en la ciudad de Buenos Aires y otro en la provincia de Prato (Italia). Los resultados de esta investigación demuestran que este sector fue pionero en los procesos de reorganización industrial en la época neoliberal. En ambos estudios de caso, el cierre de fábricas y la utilización masiva de subcontratación a talleres urbanos informales tuvieron como consecuencias una significativa concentración de capital por un lado, y un marcado deterioro de las condiciones de trabajo por el otro. De hecho, la existencia de trata de personas y reducción a la servidumbre de miles de trabajadores inmigrantes es fundamental para el funcionamiento de esta industria

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En este artículo se analiza el resurgimiento de talleres de costura clandestinos en grandes ciudades del centro y la periferia mundial, para entender los cambios dados en la industria de la moda durante las últimas cuatro décadas y sus consecuencias sobre los trabajadores. Para ello se realizaron dos estudios de caso: uno en la ciudad de Buenos Aires y otro en la provincia de Prato (Italia). Los resultados de esta investigación demuestran que este sector fue pionero en los procesos de reorganización industrial en la época neoliberal. En ambos estudios de caso, el cierre de fábricas y la utilización masiva de subcontratación a talleres urbanos informales tuvieron como consecuencias una significativa concentración de capital por un lado, y un marcado deterioro de las condiciones de trabajo por el otro. De hecho, la existencia de trata de personas y reducción a la servidumbre de miles de trabajadores inmigrantes es fundamental para el funcionamiento de esta industria

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Water exchange between the Black Sea and the Mediterranean Sea has been a major focus of the paleohydrography of the eastern Mediterranean. Glacial melt water released from the Black Sea is a potential factor in the formation of sapropel S1, an organic-rich sediment layer that accumulated during the Early Holocene. A high-resolution study done on sediments from the Marmara Sea, the gateway between the Mediterranean and the Black Sea, sheds light on the Holocene exchange processes. Past sea surface temperature and sea surface salinity (SSS) were derived from stable oxygen isotope ratios (delta18O) of foraminiferal calcite and alkenone unsaturation ratios (Uk'37). Heavy delta18O values and high SSS in the Marmara Sea suggest absence of low salinity water from the Black Sea during S1. The comparison with data from the Levantine Basin and southern Aegean Sea outlines gradients of freshening in the eastern Mediterranean Sea, whereby the major sources of freshwater were closer to the Levantine Basin. It is thus concluded that the Black Sea was not a major freshwater source contributing to formation of S1. Given the absence of a low salinity layer, the deposition of organic-rich sediments corresponding to S1 in the Marmara Sea is likely the result of the global transgression and the concomitant re-organization of biogeochemical cycles, leading to enhanced productivity as shown by Globigerina bulloides.

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A Região do Grande ABCD Paulista destaca-se por abrigar o mais significativo pólo industrial brasileiro. No entanto, muitas indústrias da região têm se retirado ocasionando desta forma, mudanças na estrutura social e econômica. Observa-se então que as cooperativas da Região do Grande ABCD Paulista começam a ganhar vitalização. As cooperativas neste momento de globalização se destacam em vários países, sendo elas, em essência associações de pessoas reunidas por um ou mais objetivos comuns. As principais perguntas que norteiam esta pesquisa são a representatividade dos ramos das cooperativas na Região do Grande ABCD Paulista, e suas contribuições sociais para a região. A natureza da pesquisa é exploratória, apresentando revisão bibliográfica desde o surgimento do cooperativismo até os dias atuais, fundamentada em um estudo de caso de uma cooperativa do ramo de transporte. Os dados foram coletados em base documental e entrevistas com cooperados, funcionários e diretores. No caso da cooperativa pesquisada o estudo proporcionou evidências significativas da melhoria de vida de seus cooperados, bem como a expansão da própria cooperativa, principalmente pela aquisição de sua sede própria., além do posicionamento como referência da sua logo marca no nicho de mercado em que atua.(AU)

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A Região do Grande ABCD Paulista destaca-se por abrigar o mais significativo pólo industrial brasileiro. No entanto, muitas indústrias da região têm se retirado ocasionando desta forma, mudanças na estrutura social e econômica. Observa-se então que as cooperativas da Região do Grande ABCD Paulista começam a ganhar vitalização. As cooperativas neste momento de globalização se destacam em vários países, sendo elas, em essência associações de pessoas reunidas por um ou mais objetivos comuns. As principais perguntas que norteiam esta pesquisa são a representatividade dos ramos das cooperativas na Região do Grande ABCD Paulista, e suas contribuições sociais para a região. A natureza da pesquisa é exploratória, apresentando revisão bibliográfica desde o surgimento do cooperativismo até os dias atuais, fundamentada em um estudo de caso de uma cooperativa do ramo de transporte. Os dados foram coletados em base documental e entrevistas com cooperados, funcionários e diretores. No caso da cooperativa pesquisada o estudo proporcionou evidências significativas da melhoria de vida de seus cooperados, bem como a expansão da própria cooperativa, principalmente pela aquisição de sua sede própria., além do posicionamento como referência da sua logo marca no nicho de mercado em que atua.(AU)

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Paper submitted to the 44th European Congress of the European Regional Science Association, Porto, 25-29 August 2004.

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A study has been performed on the Cretaceous to Early Miocene succession of the Vrancea Nappe (Outer Carpathians, Romania), based on field reconstruction of the stratigraphic record, mineralogical-petrographic and geochemical analyses. Extra-basinal clastic supply and intra-basinal autochthonous deposits have been differentiated, appearing laterally inter-fingered and/or interbedded. The main clastic petrofacies consist of calcarenites, sub-litharenites, quartzarenites, sub-arkoses, and polygenic conglomerates derived from extra-basinal margins. An alternate internal and external provenance of the different supplies is the result of the paleogeographic re-organization of the basin/margins system due to tectonic activation and exhumation of rising areas. The intra-basinal deposits consist of black shales and siliceous sediments (silexites and cherty beds), evidencing major environmental changes in the Moldavidian Basin. Organic-matter-rich black shales were deposited during anoxic episodes related to sediment starvation and high nutrient influx due to paleogeographic isolation of the basin caused by plate drifting. The black shales display relatively high contents in sub-mature to mature, Type II lipidic organic matter (good oil and gas-prone source rocks) constituting a potentially active petroleum system. The intra-basinal siliceous sediments are related to oxic pelagic or hemipelagic environments under tectonic quiescence conditions although its increase in the Oligocene part of the succession can be correlated with volcanic supplies. The integration of all the data in the “progressive reorientation of convergence direction” Carpathian model, and their consideration in the framework of a foreland basin, led to propose some constrains on the paleogeographic-geodynamic evolutionary model of the Moldavidian Basin from the Late Cretaceous to the Burdigalian.

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A Região do Grande ABCD Paulista destaca-se por abrigar o mais significativo pólo industrial brasileiro. No entanto, muitas indústrias da região têm se retirado ocasionando desta forma, mudanças na estrutura social e econômica. Observa-se então que as cooperativas da Região do Grande ABCD Paulista começam a ganhar vitalização. As cooperativas neste momento de globalização se destacam em vários países, sendo elas, em essência associações de pessoas reunidas por um ou mais objetivos comuns. As principais perguntas que norteiam esta pesquisa são a representatividade dos ramos das cooperativas na Região do Grande ABCD Paulista, e suas contribuições sociais para a região. A natureza da pesquisa é exploratória, apresentando revisão bibliográfica desde o surgimento do cooperativismo até os dias atuais, fundamentada em um estudo de caso de uma cooperativa do ramo de transporte. Os dados foram coletados em base documental e entrevistas com cooperados, funcionários e diretores. No caso da cooperativa pesquisada o estudo proporcionou evidências significativas da melhoria de vida de seus cooperados, bem como a expansão da própria cooperativa, principalmente pela aquisição de sua sede própria., além do posicionamento como referência da sua logo marca no nicho de mercado em que atua.(AU)

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This paper takes a practice perspective on organizing, re-conceptualizing coordination mechanisms as dynamic activities that are under continuous construction and modification in order to socially accomplish intra-organizational relationships and activities. The paper is based on the case of Servico, an organization undergoing a major reorganization of its value chain in response to a change in government regulation. We examine the specific performances through which the ostensive and abstract character of a coordination mechanism, ‘end-to-end management’, is defined and refined into a set of activities that actors can use to effect the re-organization of relationships between two divisions during the delivery of a critical regulatory goal. We find six cycles of iteration between the ostensive and performative nature of end-to-end, which progressively help to organize three phases in the reorganization of Servico; absence, presence and formalization. The discussion examines the processual evolution of these cycles and phases and their implications for the way that reorganization occurred. We draw these findings together in a process model that makes contributions to the literature on organizing, on ostensive and performative routines, and on organizational restructuring.

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This paper takes a practice perspective on organizing, re-conceptualizing coordination mechanisms as dynamic activities that are under continuous construction and modification in order to socially accomplish intra-organizational relationships and activities. The paper is based on the case of Servico, an organization undergoing a major reorganization of its value chain in response to a change in government regulation. We examine the specific performances through which the ostensive and abstract character of a coordination mechanism, ‘end-to-end management’, is defined and refined into a set of activities that actors can use to effect the re-organization of relationships between two divisions during the delivery of a critical regulatory goal. We find six cycles of iteration between the ostensive and performative nature of end-to-end, which progressively help to organize three phases in the reorganization of Servico; absence, presence and formalization. The discussion examines the processual evolution of these cycles and phases and their implications for the way that reorganization occurred. We draw these findings together in a process model that makes contributions to the literature on organizing, on ostensive and performative routines, and on organizational restructuring.

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Under conditions of hypoxia, most eukaryotic cells undergo a shift in metabolic strategy, which involves increased flux through the glycolytic pathway. Although this is critical for bioenergetic homeostasis, the underlying mechanisms have remained incompletely understood. Here, we report that the induction of hypoxia-induced glycolysis is retained in cells when gene transcription or protein synthesis are inhibited suggesting the involvement of additional post-translational mechanisms. Post-translational protein modification by the small ubiquitin related modifier-1 (SUMO-1) is induced in hypoxia and mass spectrometric analysis using yeast cells expressing tap-tagged Smt3 (the yeast homolog of mammalian SUMO) revealed hypoxia-dependent modification of a number of key glycolytic enzymes. Overexpression of SUMO-1 in mammalian cancer cells resulted in increased hypoxia-induced glycolysis and resistance to hypoxia-dependent ATP depletion. Supporting this, non-transformed cells also demonstrated increased glucose uptake upon SUMO-1 overexpression. Conversely, cells overexpressing the de-SUMOylating enzyme SENP-2 failed to demonstrate hypoxia-induced glycolysis. SUMO-1 overexpressing cells demonstrated focal clustering of glycolytic enzymes in response to hypoxia leading us to hypothesize a role for SUMOylation in promoting spatial re-organization of the glycolytic pathway. In summary, we hypothesize that SUMO modification of key metabolic enzymes plays an important role in shifting cellular metabolic strategies toward increased flux through the glycolytic pathway during periods of hypoxic stress. © 2011 by The American Society for Biochemistry and Molecular Biology, Inc.

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Background & Aims - Hepatitis C virus (HCV) infection leads to progressive liver disease, frequently culminating in fibrosis and hepatocellular carcinoma. The mechanisms underlying liver injury in chronic hepatitis C are poorly understood. This study evaluated the role of vascular endothelial growth factor (VEGF) in hepatocyte polarity and HCV infection. Methods - We used polarized hepatoma cell lines and the recently described infectious HCV Japanese fulminant hepatitis (JFH)-1 cell culture system to study the role of VEGF in regulating hepatoma permeability and HCV infection. Results - VEGF negatively regulates hepatocellular tight junction integrity and cell polarity by a novel VEGF receptor 2–dependent pathway. VEGF reduced hepatoma tight junction integrity, induced a re-organization of occludin, and promoted HCV entry. Conversely, inhibition of hepatoma expressed VEGF with the receptor kinase inhibitor sorafenib or with neutralizing anti-VEGF antibodies promoted polarization and inhibited HCV entry, showing an autocrine pathway. HCV infection of primary hepatocytes or hepatoma cell lines promoted VEGF expression and reduced their polarity. Importantly, treatment of HCV-infected cells with VEGF inhibitors restored their ability to polarize, showing a VEGF-dependent pathway. Conclusions - Hepatic polarity is critical to normal liver physiology. HCV infection promotes VEGF expression that depolarizes hepatoma cells, promoting viral transmission and lymphocyte migration into the parenchyma that may promote hepatocyte injury.

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Purpose: To establish and sustain their KM programs organizations need to establish mechanisms to ensure their governance. KM programs require business integration, senior management involvement and decision making authority. The present research investigates the KM governance mechanisms organizations use to guide and control their KM programs. The research seeks to contribute to a better understanding of the governance of KM and to support organizations in the development of their KM programs. Methodology: The study employs multiple case research methodology to analyze the KM governance arrangements of twelve international organizations and identify patterns in their governance configurations. Findings: The analysis identifies a range of structural, process and relational mechanisms that are critical for governing an organizational KM program. Different patterns among the KM governance mechanisms are identified which lead to the development of generic KM governance typologies. Research implications: The development of the KM governance framework allows future research to systematically investigate the KM governance phenomenon. As the present study is based on a configurational analysis future research should particularly target the performance implications of different KM governance configurations. Practical implications: The research provides insights into the diversity of KM governance mechanisms and their impact on a KM program. The KM governance framework can assist managers in reviewing their present and prospective KM programs and thereby support benchmarking or re-organization efforts. Originality: Building on prior research that has focused on individual KM governance aspects, the present study adopts a comprehensive perspective integrating structural, process and relational governance mechanisms.

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Up to January 2011 authoritarian political regimes in the Middle East had widely been considered stable due to the armed forces, the underdeveloped political institutions, the economic embeddedness of the regimes, the neo-patrimonial structure of the Arab societies and, eventually the characteristics of Islam. Middle Eastern political systems are often considered to belong to a special sub-group of non-democratic regimes called “liberalized autocracies”. The 2011 events show that there is a new, as yet non-defined political structure emerging. Although there are different interpretations of the developments, there is a consensus on the determinant role of the Islamist organizations in the development of the new political structure. The results of the Egyptian and Tunisian parliamentary elections show that the secular political parties could not attract the public, while in Tunisia the long forbidden Hizb an-Nahda could form a government. In Egypt Hizb al-Hurriya established by the Muslim Brotherhood in 2011 won almost half of the parliamentary mandates, and to a great surprise, the Salafi Hizb an-Nour also received 24.3% of the votes. On the basis of the above developments the thesis of the Islamist re-organization of the Middle East, i.e. of a new wave of Islamism was elaborated, according to which the main political winners of the revolts in the Arab countries are the Islamist organizations, which could step in and fill in the political vacuum. While some speak of an Islamist autumn or Islamist winter as the result of the Arab Spring, others prefer the term Islamic revolutions.

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Recent proxy measurements reveal that subglacial lakes beneath modern ice sheets periodically store and release large volumes of water, providing an important but poorly understood influence on contemporary ice dynamics and mass balance. This is because direct observations of how lake drainage initiates and proceeds are lacking. Here we present physical evidence of the mechanism and geometry of lake drainage from the discovery of relict subglacial lakes formed during the last glaciation in Canada. These palaeo-subglacial lakes comprised shallow (<10 m) lenses of water perched behind ridges orientated transverse to ice flow. We show that lakes periodically drained through channels incised into bed substrate (canals). Canals sometimes trend into eskers that represent the depositional imprint of the last high-magnitude lake outburst. The subglacial lakes and channels are preserved on top of glacial lineations, indicating long-term re-organization of the subglacial drainage system and coupling to ice flow.